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Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

  • Patricia Spilman,

    Affiliation The Buck Institute for Age Research, Novato, California, United States of America

  • Natalia Podlutskaya,

    Affiliations Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

  • Matthew J. Hart,

    Affiliation Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

  • Jayanta Debnath,

    Affiliation Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

  • Olivia Gorostiza,

    Affiliation The Buck Institute for Age Research, Novato, California, United States of America

  • Dale Bredesen,

    Affiliation The Buck Institute for Age Research, Novato, California, United States of America

  • Arlan Richardson,

    Affiliations The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Geriatric Research, Education and Clinical Center and Research Service, South Texas Veterans Health Care System, San Antonio, Texas, United States of America

  • Randy Strong,

    Affiliations The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Geriatric Research, Education and Clinical Center and Research Service, South Texas Veterans Health Care System, San Antonio, Texas, United States of America

  • Veronica Galvan

    galvanv@uthscsa.edu

    Affiliations Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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