Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population

• Michele Mishto ,

  * E-mail: michele.mishto@charite.de

  Affiliations Department of Experimental Pathology, University of Bologna, Bologna, Italy, Interdepartmental Center for Studies on Biophysics, Bioinformatics and Biocomplexity ‘L. Galvani’ (CIG), Bologna, Italy, Institute of Biochemistry, Medical Faculty Charité, Berlin, Germany

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• Elena Bellavista,

  Affiliation Interdepartmental Center for Studies on Biophysics, Bioinformatics and Biocomplexity ‘L. Galvani’ (CIG), Bologna, Italy

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• Claudia Ligorio,

  Affiliation Department of Hematology and Oncology, Section of Anatomic Pathology, University of Bologna and Bellaria Hospital, Bologna, Italy

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• Kathrin Textoris-Taube,

  Affiliation Institute of Biochemistry, Medical Faculty Charité, Berlin, Germany

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• Aurelia Santoro,

  Affiliations Department of Experimental Pathology, University of Bologna, Bologna, Italy, Interdepartmental Center for Studies on Biophysics, Bioinformatics and Biocomplexity ‘L. Galvani’ (CIG), Bologna, Italy

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• Mara Giordano,

  Affiliation Department of Medical Sciences and IRCAD (Interdisciplinary Research Center of Autoimmune Diseases), University of Eastern Piedmont, Novara, Italy

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• Sandra D'Alfonso,

  Affiliation Department of Medical Sciences and IRCAD (Interdisciplinary Research Center of Autoimmune Diseases), University of Eastern Piedmont, Novara, Italy

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• Florinda Listì,

  Affiliation Department of Biopathology & Biomedical Methodologies, University of Palermo, Palermo, Italy

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• Benedetta Nacmias,

  Affiliation Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy

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• Elena Cellini,

  Affiliation Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy

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• Maurizio Leone,

  Affiliation Clinica Neurologica, Ospedale Maggiore della Carità, Novara, Italy

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• Luigi M.E. Grimaldi,

  Affiliation U.O. Neurologia Fondazione, Istituto San Raffaele “G.Giglio” di Cefalù, Cefalù (PA), Italy

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• Chiara Fenoglio,

  Affiliation Department of Neurological Sciences, University of Milan, IRCCS Fondazione Ospedale Maggiore Policlinico, Milan, Italy

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• Federica Esposito,

  Affiliation Institute of Experimental Neurology (INSPE), and Department of Neurology, San Raffaele Scientific Institute, Milan, Italy

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• Filippo Martinelli-Boneschi,

  Affiliation Institute of Experimental Neurology (INSPE), and Department of Neurology, San Raffaele Scientific Institute, Milan, Italy

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• Daniela Galimberti,

  Affiliation Department of Neurological Sciences, University of Milan, IRCCS Fondazione Ospedale Maggiore Policlinico, Milan, Italy

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• Elio Scarpini,

  Affiliation Department of Neurological Sciences, University of Milan, IRCCS Fondazione Ospedale Maggiore Policlinico, Milan, Italy

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• Ulrike Seifert,

  Affiliation Institute of Biochemistry, Medical Faculty Charité, Berlin, Germany

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• Maria Pia Amato,

  Affiliation Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy

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• Calogero Caruso,

  Affiliation Department of Biopathology & Biomedical Methodologies, University of Palermo, Palermo, Italy

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• Maria P. Foschini,

  Affiliation Department of Hematology and Oncology, Section of Anatomic Pathology, University of Bologna and Bellaria Hospital, Bologna, Italy

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• Peter M. Kloetzel,

  Affiliation Institute of Biochemistry, Medical Faculty Charité, Berlin, Germany

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•  [ ... ],
• Claudio Franceschi

  Affiliations Department of Experimental Pathology, University of Bologna, Bologna, Italy, Interdepartmental Center for Studies on Biophysics, Bioinformatics and Biocomplexity ‘L. Galvani’ (CIG), Bologna, Italy

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