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Research Article

Limitations of Ab Initio Predictions of Peptide Binding to MHC Class II Molecules

  • Hao Zhang equal contributor,

    equal contributor Contributed equally to this work with: Hao Zhang, Peng Wang, Nikitas Papangelopoulos

    Affiliation: Center for Biological Sequence Analysis, Department for Systems Biology, Technical University of Denmark, Lyngby, Denmark

    X
  • Peng Wang equal contributor,

    equal contributor Contributed equally to this work with: Hao Zhang, Peng Wang, Nikitas Papangelopoulos

    Affiliation: La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America

    X
  • Nikitas Papangelopoulos equal contributor,

    equal contributor Contributed equally to this work with: Hao Zhang, Peng Wang, Nikitas Papangelopoulos

    Affiliation: San Diego Supercomputer Center and Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, San Diego, California, United States of America

    X
  • Ying Xu,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Bioinformatics, University of Georgia, Athens, Georgia, United States of America

    X
  • Alessandro Sette,

    Affiliation: La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America

    X
  • Philip E. Bourne,

    Affiliation: San Diego Supercomputer Center and Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, San Diego, California, United States of America

    X
  • Ole Lund,

    Affiliation: Center for Biological Sequence Analysis, Department for Systems Biology, Technical University of Denmark, Lyngby, Denmark

    X
  • Julia Ponomarenko,

    Affiliation: San Diego Supercomputer Center and Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, San Diego, California, United States of America

    X
  • Morten Nielsen,

    Affiliation: Center for Biological Sequence Analysis, Department for Systems Biology, Technical University of Denmark, Lyngby, Denmark

    X
  • Bjoern Peters mail

    bpeters@liai.org

    Affiliation: La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America

    X
  • Published: February 17, 2010
  • DOI: 10.1371/journal.pone.0009272

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