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Research Article

Two Multiplex Assays That Simultaneously Identify 22 Possible Mutation Sites in the KRAS, BRAF, NRAS and PIK3CA Genes

  • Irene Lurkin,

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Robert Stoehr,

    Affiliation: Institute of Pathology, University of Erlangen, Erlangen, Germany

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  • Carolyn D. Hurst,

    Affiliation: Cancer Research UK Clinical Centre, Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, United Kingdom

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  • Angela A. G. van Tilborg,

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Margaret A. Knowles,

    Affiliation: Cancer Research UK Clinical Centre, Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, United Kingdom

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  • Arndt Hartmann,

    Affiliation: Institute of Pathology, University of Erlangen, Erlangen, Germany

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  • Ellen C. Zwarthoff mail

    e.zwarthoff@erasmusmc.nl

    Affiliation: Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands

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  • Published: January 21, 2010
  • DOI: 10.1371/journal.pone.0008802

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