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Research Article

Cell Cycle Re-Entry and Mitochondrial Defects in Myc-Mediated Hypertrophic Cardiomyopathy and Heart Failure

  • Hyoung-gon Lee mail,

    hyoung-gon.lee@case.edu (HgL); mark.smith@case.edu (MAS)

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Qun Chen,

    Affiliation: Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Julie A. Wolfram,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Sandy L. Richardson,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Anna Liner,

    Affiliations: Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America

    X
  • Sandra L. Siedlak,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Xiongwei Zhu,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Nicholas P. Ziats,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Hisashi Fujioka,

    Affiliation: Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Dean W. Felsher,

    Affiliation: Division of Oncology, Department of Medicine and Pathology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Rudy J. Castellani,

    Affiliation: Department of Pathology, University of Maryland, Baltimore, Maryland, United States of America

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  • Maria L. Valencik,

    Affiliation: Department of Biochemistry, University of Nevada Reno, Reno, Nevada, United States of America

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  • John A. McDonald,

    Affiliation: Department of Biochemistry, University of Nevada Reno, Reno, Nevada, United States of America

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  • Brian D. Hoit,

    Affiliations: Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America

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  • Edward J. Lesnefsky,

    Affiliations: Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, Louis Stokes Cleveland DVAMC, Cleveland, Ohio, United States of America

    Current address: Department of Medicine, Division of Cardiology, Virginia Commonwealth University, and McGuire DVAMC, Richmond, Virginia, United States of America

    X
  • Mark A. Smith mail

    hyoung-gon.lee@case.edu (HgL); mark.smith@case.edu (MAS)

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Published: September 25, 2009
  • DOI: 10.1371/journal.pone.0007172

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