Vitamin D Status Is Positively Correlated with Regulatory T Cell Function in Patients with Multiple Sclerosis

Joost Smolders; Mariëlle Thewissen; Evelyn Peelen; Paul Menheere; Jan Willem Cohen Tervaert; Jan Damoiseaux; Raymond Hupperts

doi:10.1371/journal.pone.0006635

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Open Access

Peer-reviewed

Research Article

Vitamin D Status Is Positively Correlated with Regulatory T Cell Function in Patients with Multiple Sclerosis

Joost Smolders ,

* E-mail: j.smolders@mumc.nl

Affiliations School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands, Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Mariëlle Thewissen,

Affiliation Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Evelyn Peelen,

Affiliations School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands, Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Paul Menheere,

Affiliation Department of Clinical Chemistry, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Jan Willem Cohen Tervaert,

Affiliations School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands, Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Jan Damoiseaux,

Affiliation Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Raymond Hupperts

Affiliations School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands, Department of Neurology, Orbis Medical Center, Sittard, The Netherlands
⨯

Vitamin D Status Is Positively Correlated with Regulatory T Cell Function in Patients with Multiple Sclerosis

Joost Smolders,
Mariëlle Thewissen,
Evelyn Peelen,
Paul Menheere,
Jan Willem Cohen Tervaert,
Jan Damoiseaux,
Raymond Hupperts

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Published: August 13, 2009
https://doi.org/10.1371/journal.pone.0006635

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Regulatory T cells
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T cells
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Vitamin D
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Multiple sclerosis
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Interferons
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Autoimmune diseases
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T helper cells
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Inflammatory diseases
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