Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal

• Catherine Dostert,

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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• Greta Guarda ,

  Contributed equally to this work with: Greta Guarda, Jackeline F. Romero

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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• Jackeline F. Romero ,

  Contributed equally to this work with: Greta Guarda, Jackeline F. Romero

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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• Philippe Menu,

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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• Olaf Gross,

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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• Aubry Tardivel,

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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• Mario-Luca Suva,

  Affiliation Division of Experimental Pathology, Institute of Pathology, CHUV, Lausanne, Switzerland

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• Jean-Christophe Stehle,

  Affiliation Division of Experimental Pathology, Institute of Pathology, CHUV, Lausanne, Switzerland

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• Manfred Kopf,

  Affiliation Institut Integrative Biologie, ETH, Zürich, Switzerland

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• Ivan Stamenkovic,

  Affiliation Division of Experimental Pathology, Institute of Pathology, CHUV, Lausanne, Switzerland

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• Giampietro Corradin,

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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• Jurg Tschopp

  * E-mail: jurg.tschopp@unil.ch

  Affiliation Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

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