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Open Access

Peer-reviewed

Research Article

The Special Neuraminidase Stalk-Motif Responsible for Increased Virulence and Pathogenesis of H5N1 Influenza A Virus

  • Hongbo Zhou,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Zhengjun Yu,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Yong Hu,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Jiagang Tu,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Wei Zou,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Yaping Peng,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Jiping Zhu,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Yongtao Li,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Anding Zhang,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Ziniu Yu,

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Zhiping Ye,

    Affiliation Laboratory of Pediatric and Respiratory Viral Diseases, Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America

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  • Huanchun Chen ,

    chenhch@mail.hzau.edu.cn (HC); jinmeilin@mail.hzau.edu.cn (MJ)

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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  • Meilin Jin

    chenhch@mail.hzau.edu.cn (HC); jinmeilin@mail.hzau.edu.cn (MJ)

    Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China

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