Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies

• Ilja M. Nolte,

  Affiliation Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

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• Chris Wallace,

  Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

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• Stephen J. Newhouse,

  Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

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• Daryl Waggott,

  Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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• Jingyuan Fu,

  Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

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• Nicole Soranzo,

  Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Department of Twin Research and Genetic Epidemiology Unit, St Thomas' Campus, King's College London, St Thomas' Hospital, London, United Kingdom

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• Rhian Gwilliam,

  Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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• Panos Deloukas,

  Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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• Irina Savelieva,

  Affiliation Cardiological Sciences, Division of Cardiac and Vascular Sciences, St George's University of London, London, United Kingdom

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• Dongling Zheng,

  Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

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• Chrysoula Dalageorgou,

  Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

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• Martin Farrall,

  Affiliation Department of Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

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• Nilesh J. Samani,

  Affiliation Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom

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• John Connell,

  Affiliation BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kindom

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• Morris Brown,

  Affiliation Clinical Pharmacology and the Cambridge Institute of Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

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• Anna Dominiczak,

  Affiliation BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kindom

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• Mark Lathrop,

  Affiliation Centre National de Genotypage, Evry, France

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• Eleftheria Zeggini,

  Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

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• Louise V. Wain,

  Affiliation Departments of Health Sciences & Genetics, University of Leicester, Leicester, United Kingdom

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• for the The Wellcome Trust Case Control Consortium ,

  ¶^aFor the full author list see Appendix S1.

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• The DCCT/EDIC Research Group ,

  ¶^bA complete list of investigators and members of the DCCT/EDIC Research Group appears in N Engl J Med 2005; 353(25):2643–53.

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• Christopher Newton-Cheh,

  Affiliations Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, NHLBI's Framingham Heart Study, Framingham, Massachusetts, United States of America

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• Mark Eijgelsheim,

  Affiliation Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

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• Kenneth Rice,

  Affiliation Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

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• Paul I. W. de Bakker,

  Affiliations Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School-Partners HealthCare Center for Genetics and Genomics, Boston, Massachusetts, United States of America

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• for the QTGEN consortium ,

  ¶^cA complete list of investigators and members of the QTGEN consortium appears in Appendix S1.

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• Arne Pfeufer,

  Affiliations Institute of Human Genetics, Technical University Munich, Munich, Germany, Institute of Human Genetics, Helmholtz Center Munich, Munich, Germany

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• Serena Sanna,

  Affiliation Istituto di Neurogenetica e Neurofarmacologia, CNR, Monserrato, Cagliari, Italy

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• Dan E. Arking,

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

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• for the QTSCD consortium ,

  ¶^dA complete list of investigators and members of the QTSCD consortium appears in Appendix S1.

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• Folkert W. Asselbergs,

  Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

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• Tim D. Spector,

  Affiliation Department of Twin Research and Genetic Epidemiology Unit, St Thomas' Campus, King's College London, St Thomas' Hospital, London, United Kingdom

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• Nicholas D. Carter,

  Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

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• Steve Jeffery,

  Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

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• Martin Tobin,

  Affiliation Departments of Health Sciences & Genetics, University of Leicester, Leicester, United Kingdom

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• Mark Caulfield,

  Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

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• Harold Snieder,

  Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Department of Twin Research and Genetic Epidemiology Unit, St Thomas' Campus, King's College London, St Thomas' Hospital, London, United Kingdom

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• Andrew D. Paterson,

  Affiliation Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Patricia B. Munroe ,

  Contributed equally to this work with: Patricia B. Munroe, Yalda Jamshidi

  Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

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•  [ ... ],
• Yalda Jamshidi

  Contributed equally to this work with: Patricia B. Munroe, Yalda Jamshidi

  * E-mail: y.jamshidi@sgul.ac.uk

  Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

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