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The Y271 and I274 Amino Acids in Reverse Transcriptase of Human Immunodeficiency Virus-1 Are Critical to Protein Stability

  • Hao-Jie Zhang ,

    Contributed equally to this work with: Hao-Jie Zhang, Yong-Xiang Wang

    Affiliation Department of Microbiology, the University of Hong Kong, Hong Kong SAR, People's Republic of China

  • Yong-Xiang Wang ,

    Contributed equally to this work with: Hao-Jie Zhang, Yong-Xiang Wang

    Affiliation Key Laboratory of Medical Molecular Virology, Institute of Medical Microbiology, Shanghai Medical College, Fudan University, Shanghai, China

  • Hao Wu,

    Affiliation Department of Microbiology, the University of Hong Kong, Hong Kong SAR, People's Republic of China

  • Dong-Yan Jin,

    Affiliation Department of Biochemistry, the University of Hong Kong, Hong Kong SAR, People's Republic of China

  • Yu-Mei Wen ,

    ymwen@shmu.edu.cn (YMW); bzheng@hkucc.hku.hk (BJZ)

    Affiliation Key Laboratory of Medical Molecular Virology, Institute of Medical Microbiology, Shanghai Medical College, Fudan University, Shanghai, China

  • Bo-Jian Zheng

    ymwen@shmu.edu.cn (YMW); bzheng@hkucc.hku.hk (BJZ)

    Affiliation Department of Microbiology, the University of Hong Kong, Hong Kong SAR, People's Republic of China

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