Quantitative Deep Sequencing Reveals Dynamic HIV-1 Escape and Large Population Shifts during CCR5 Antagonist Therapy In Vivo

• Athe M. N. Tsibris,

  Affiliations Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Bette Korber ,

  Contributed equally to this work with: Bette Korber, Ramy Arnaout

  Affiliations Los Alamos National Laboratories, Los Alamos, New Mexico, United States of America, Santa Fe Institute, Santa Fe, New Mexico, United States of America

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• Ramy Arnaout ,

  Contributed equally to this work with: Bette Korber, Ramy Arnaout

  Affiliations Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Program for Evolutionary Dynamics, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Carsten Russ,

  Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Chien-Chi Lo,

  Affiliation Los Alamos National Laboratories, Los Alamos, New Mexico, United States of America

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• Thomas Leitner,

  Affiliation Los Alamos National Laboratories, Los Alamos, New Mexico, United States of America

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• Brian Gaschen,

  Affiliation Los Alamos National Laboratories, Los Alamos, New Mexico, United States of America

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• James Theiler,

  Affiliation Los Alamos National Laboratories, Los Alamos, New Mexico, United States of America

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• Roger Paredes,

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Fundacions irsiCaixa i Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Catalonia, Spain

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• Zhaohui Su,

  Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Michael D. Hughes,

  Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Roy M. Gulick,

  Affiliation Weill Medical College, Cornell University, New York, New York, United States of America

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• Wayne Greaves,

  Affiliation Schering-Plough Research Institute, Kennilworth, New Jersey, United States of America

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• Eoin Coakley,

  Affiliation Monogram Biosciences, South San Francisco, California, United States of America

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• Charles Flexner,

  Affiliation Johns Hopkins University, Baltimore, Maryland, United States of America

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• Chad Nusbaum,

  Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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•  [ ... ],
• Daniel R. Kuritzkes

  * E-mail: dkuritzkes@partners.org

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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