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Research Article

A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme—A Preclinical and Phase I Investigation

  • David Aviezer,

    Affiliation: Protalix Biotherapeutics, Science Park, Carmiel, Israel

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  • Einat Brill-Almon,

    Affiliation: Protalix Biotherapeutics, Science Park, Carmiel, Israel

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  • Yoseph Shaaltiel,

    Affiliation: Protalix Biotherapeutics, Science Park, Carmiel, Israel

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  • Sharon Hashmueli,

    Affiliation: Protalix Biotherapeutics, Science Park, Carmiel, Israel

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  • Daniel Bartfeld,

    Affiliation: Protalix Biotherapeutics, Science Park, Carmiel, Israel

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  • Sarah Mizrachi,

    Affiliation: Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Hospital, Jerusalem, Israel

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  • Yael Liberman,

    Affiliation: Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Hospital, Jerusalem, Israel

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  • Arnold Freeman,

    Affiliation: Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Hospital, Jerusalem, Israel

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  • Ari Zimran,

    Affiliation: Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem, Israel

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  • Eithan Galun mail

    eithang@hadassah.org.il

    Affiliation: Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Hospital, Jerusalem, Israel

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  • Published: March 11, 2009
  • DOI: 10.1371/journal.pone.0004792

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