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Research Article

In Vitro Priming Recapitulates In Vivo HIV-1 Specific T Cell Responses, Revealing Rapid Loss of Virus Reactive CD4+ T Cells in Acute HIV-1 Infection

  • Rachel Lubong Sabado,

    Affiliation: New York University School of Medicine, New York, New York, United States of America

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  • Daniel G. Kavanagh,

    Affiliation: Partners AIDS Research Center (PARC), Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

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  • Daniel E. Kaufmann,

    Affiliation: Partners AIDS Research Center (PARC), Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

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  • Karlhans Fru,

    Affiliation: Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

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  • Ethan Babcock,

    Affiliation: New York University School of Medicine, New York, New York, United States of America

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  • Eric Rosenberg,

    Affiliation: Partners AIDS Research Center (PARC), Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

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  • Bruce Walker,

    Affiliation: Partners AIDS Research Center (PARC), Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

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  • Jeffrey Lifson,

    Affiliation: SAIC Fredrick, Inc., National Cancer Institute, Fredrick, Frederick, Maryland, United States of America

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  • Nina Bhardwaj,

    Affiliation: New York University School of Medicine, New York, New York, United States of America

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  • Marie Larsson mail

    marla@imk.liu.se

    Affiliation: Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

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  • Published: January 23, 2009
  • DOI: 10.1371/journal.pone.0004256

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