Comprehensive Biostatistical Analysis of CpG Island Methylator Phenotype in Colorectal Cancer Using a Large Population-Based Sample

• Katsuhiko Nosho ,

  Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

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• Natsumi Irahara ,

  Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

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• Kaori Shima ,

  Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

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• Shoko Kure ,

  Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

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• Gregory J. Kirkner,

  Affiliation Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Eva S. Schernhammer,

  Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Ludwig Boltzmann-Institute for Applied Cancer Research, and Applied Cancer Research – Institute for Translational Research, Vienna, Austria, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Aditi Hazra,

  Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• David J. Hunter,

  Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• John Quackenbush,

  Affiliations Department of Biostatistics, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Donna Spiegelman,

  Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Edward L. Giovannucci,

  Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Charles S. Fuchs,

  Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Shuji Ogino

  * E-mail: shuji_ogino@dfci.harvard.edu

  Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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