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Research Article

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

  • Patrick M. Loerch equal contributor,

    equal contributor Contributed equally to this work with: Patrick M. Loerch, Tao Lu

    Affiliations: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Biostatistics, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • Tao Lu equal contributor,

    equal contributor Contributed equally to this work with: Patrick M. Loerch, Tao Lu

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Kelly A. Dakin,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • James M. Vann,

    Affiliation: Department of Genetics and Medical Genetics, University of Wisconsin, Madison, Wisconsin, United States of America

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  • Adrian Isaacs,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Chengiz Geula,

    Affiliation: Cognitive Neurology and Alzheimer's Disease Center, Northwestern University, Chicago, Illinois, United States of America

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  • Jianbin Wang,

    Affiliation: Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Ying Pan,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Dana H. Gabuzda,

    Affiliation: Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Cheng Li,

    Affiliation: Department of Biostatistics, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts, United States of America

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  • Tomas A. Prolla,

    Affiliation: Department of Genetics and Medical Genetics, University of Wisconsin, Madison, Wisconsin, United States of America

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  • Bruce A. Yankner mail

    bruce_yankner@hms.harvard.edu

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: October 02, 2008
  • DOI: 10.1371/journal.pone.0003329

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