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Research Article

Synthetic Activation of Endogenous PI3K and Rac Identifies an AND-Gate Switch for Cell Polarization and Migration

  • Takanari Inoue mail,

    tobias1@stanford.edu (TM); jctinoue@jhmi.edu (TI)

    Affiliation: Chemical and Systems Biology, Bio-X Program, Stanford University, Stanford, California, United States of America

    Current address: Department of Cell Biology, School of Medicine, Institute of Basic Biomedical Sciences, Center for Cell Dynamics Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Tobias Meyer mail

    tobias1@stanford.edu (TM); jctinoue@jhmi.edu (TI)

    Affiliation: Chemical and Systems Biology, Bio-X Program, Stanford University, Stanford, California, United States of America

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  • Published: August 27, 2008
  • DOI: 10.1371/journal.pone.0003068

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