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Dynamical Systems Analysis of Mitochondrial BAK Activation Kinetics Predicts Resistance to BH3 Domains

  • Claire Grills,

    Affiliation School of Applied Mathematics and Theoretical Physics, Queens University Belfast, Belfast, Northern Ireland

  • Nyree Crawford,

    Affiliation Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, Northern Ireland

  • Alex Chacko,

    Affiliation Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, Northern Ireland

  • Patrick G. Johnston,

    Affiliations Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, Northern Ireland, Northern Ireland Cancer Centre, Belfast, Northern Ireland

  • Francesca O'Rourke,

    Affiliations School of Applied Mathematics and Theoretical Physics, Queens University Belfast, Belfast, Northern Ireland, Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, Northern Ireland

  • Dean A. Fennell

    d.fennell@qub.ac.uk

    Affiliations Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, Northern Ireland, Northern Ireland Cancer Centre, Belfast, Northern Ireland

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