Live Imaging of Cysteine-Cathepsin Activity Reveals Dynamics of Focal Inflammation, Angiogenesis, and Polyp Growth

• Elias Gounaris,

  Affiliations Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America, Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Robert Lurie Comprehensive Cancer Center, Chicago, Illinois, United States of America

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• Ching H. Tung,

  Affiliations Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas, United States of America

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• Clifford Restaino,

  Affiliation Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• René Maehr,

  Affiliations Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Cambridge, Massachusetts, United States of America

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• Rainer Kohler,

  Affiliation Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• Johanna A. Joyce,

  Affiliation Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Hidde L. Plough,

  Affiliation Whitehead Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Terrence A. Barrett,

  Affiliation Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Robert Lurie Comprehensive Cancer Center, Chicago, Illinois, United States of America

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• Ralph Weissleder,

  Affiliation Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• Khashayarsha Khazaie

  * E-mail: khazaie@northwestern.edu

  Affiliations Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America, Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Robert Lurie Comprehensive Cancer Center, Chicago, Illinois, United States of America

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