Non-Syndromic Tooth Agenesis in Two Chinese Families Associated with Novel Missense Mutations in the TNF Domain of EDA (Ectodysplasin A)

Shufeng Li; Jiahuang Li; Jian Cheng; Bingrong Zhou; Xin Tong; Xiangbai Dong; Zixing Wang; Qingang Hu; Meng Chen; Zi-Chun Hua

doi:10.1371/journal.pone.0002396

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Peer-reviewed

Research Article

Non-Syndromic Tooth Agenesis in Two Chinese Families Associated with Novel Missense Mutations in the TNF Domain of EDA (Ectodysplasin A)

Shufeng Li ,

Contributed equally to this work with: Shufeng Li, Jiahuang Li, Jian Cheng, Bingrong Zhou, Xin Tong

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Jiahuang Li ,

Contributed equally to this work with: Shufeng Li, Jiahuang Li, Jian Cheng, Bingrong Zhou, Xin Tong

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Jian Cheng ,

Contributed equally to this work with: Shufeng Li, Jiahuang Li, Jian Cheng, Bingrong Zhou, Xin Tong

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Bingrong Zhou ,

Contributed equally to this work with: Shufeng Li, Jiahuang Li, Jian Cheng, Bingrong Zhou, Xin Tong

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Xin Tong ,

Contributed equally to this work with: Shufeng Li, Jiahuang Li, Jian Cheng, Bingrong Zhou, Xin Tong

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Xiangbai Dong,

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Zixing Wang,

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Qingang Hu,

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Meng Chen,

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯
Zi-Chun Hua

* E-mail: zchua@nju.edu.cn

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China
⨯

Non-Syndromic Tooth Agenesis in Two Chinese Families Associated with Novel Missense Mutations in the TNF Domain of EDA (Ectodysplasin A)

Shufeng Li,
Jiahuang Li,
Jian Cheng,
Bingrong Zhou,
Xin Tong,
Xiangbai Dong,
Zixing Wang,
Qingang Hu,
Meng Chen,
Zi-Chun Hua

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Published: June 11, 2008
https://doi.org/10.1371/journal.pone.0002396

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Teeth
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Point mutation
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Dentition
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X-linked traits
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Mutation detection
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Missense mutation
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Molars
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