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Research Article

Distinct Methylation Changes at the IGF2-H19 Locus in Congenital Growth Disorders and Cancer

  • Adele Murrell mail,

    amm207@cam.ac.uk

    Affiliation: Department of Oncology, University of Cambridge, CRUK Cambridge Research Institute, Cambridge, United Kingdom

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  • Yoko Ito equal contributor,

    equal contributor Contributed equally to this work with: Yoko Ito, Gaetano Verde

    Affiliation: Department of Oncology, University of Cambridge, CRUK Cambridge Research Institute, Cambridge, United Kingdom

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  • Gaetano Verde equal contributor,

    equal contributor Contributed equally to this work with: Yoko Ito, Gaetano Verde

    Affiliation: Dipartimento di Scienze Ambientali, Seconda Università di Napoli, Caserta, Italy

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  • Joanna Huddleston,

    Affiliation: Department of Oncology, University of Cambridge, CRUK Cambridge Research Institute, Cambridge, United Kingdom

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  • Kathryn Woodfine,

    Affiliation: Department of Oncology, University of Cambridge, CRUK Cambridge Research Institute, Cambridge, United Kingdom

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  • Margherita Cirillo Silengo,

    Affiliation: Dipartimento di Scienze Pediatriche e dell'Adolescenza, Università di Torino, Torino, Italy

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  • Filippo Spreafico,

    Affiliation: Pediatric Oncology Unit, Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy

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  • Daniela Perotti,

    Affiliation: Department of Experimental Oncology and Laboratories, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy

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  • Agostina De Crescenzo,

    Affiliations: Dipartimento di Scienze Ambientali, Seconda Università di Napoli, Caserta, Italy, Institute of Genetics and Biophysics “A. Buzzati Traverso”, Consiglio Nazionale delle Ricerche (CNR), Naples, Italy

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  • Angela Sparago,

    Affiliations: Dipartimento di Scienze Ambientali, Seconda Università di Napoli, Caserta, Italy, Institute of Genetics and Biophysics “A. Buzzati Traverso”, Consiglio Nazionale delle Ricerche (CNR), Naples, Italy

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  • Flavia Cerrato,

    Affiliations: Dipartimento di Scienze Ambientali, Seconda Università di Napoli, Caserta, Italy, Institute of Genetics and Biophysics “A. Buzzati Traverso”, Consiglio Nazionale delle Ricerche (CNR), Naples, Italy

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  • Andrea Riccio

    Affiliations: Dipartimento di Scienze Ambientali, Seconda Università di Napoli, Caserta, Italy, Institute of Genetics and Biophysics “A. Buzzati Traverso”, Consiglio Nazionale delle Ricerche (CNR), Naples, Italy

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  • Published: March 26, 2008
  • DOI: 10.1371/journal.pone.0001849

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