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Research Article

The INT6 Cancer Gene and MEK Signaling Pathways Converge during Zebrafish Development

  • Michal Grzmil,

    Affiliation: Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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  • Danny Whiting,

    Affiliation: Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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  • John Maule,

    Affiliation: MRC Human Genetics Unit and University of Edinburgh Cancer Research Centre, Western General Hospital, Edinburgh, United Kingdom

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  • Corina Anastasaki,

    Affiliation: MRC Human Genetics Unit and University of Edinburgh Cancer Research Centre, Western General Hospital, Edinburgh, United Kingdom

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  • James F. Amatruda,

    Affiliation: Departments of Pediatrics, Internal Medicine and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Robert N. Kelsh,

    Affiliation: Centre for Regenerative Medicine, Developmental Biology Programme, Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom

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  • Chris J. Norbury,

    Affiliation: Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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  • E. Elizabeth Patton mail

    To whom correspondence should be addressed. E-mail: epatton@staffmail.ed.ac.uk

    Affiliations: Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom, MRC Human Genetics Unit and University of Edinburgh Cancer Research Centre, Western General Hospital, Edinburgh, United Kingdom

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  • Published: September 26, 2007
  • DOI: 10.1371/journal.pone.0000959

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