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Research Article

Constitutive Phosphorylation of Aurora-A on Ser51 Induces Its Stabilization and Consequent Overexpression in Cancer

  • Shojiro Kitajima equal contributor,

    equal contributor Contributed equally to this work with: Shojiro Kitajima, Yasusei Kudo

    Affiliation: Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan

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  • Yasusei Kudo equal contributor mail,

    equal contributor Contributed equally to this work with: Shojiro Kitajima, Yasusei Kudo

    To whom correspondence should be addressed. E-mail: ykudo@hiroshima-u.ac.jp (YK); ttakata@hiroshima-u.ac.jp (TT)

    Affiliation: Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan

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  • Ikuko Ogawa,

    Affiliation: Center of Oral Clinical Examination, Hiroshima University Hospital, Hiroshima, Japan

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  • Masaaki Tatsuka,

    Affiliation: Department of Regulatory Radiobiology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan

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  • Hidehiko Kawai,

    Affiliation: Department of Regulatory Radiobiology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan

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  • Michele Pagano,

    Affiliation: Department of Pathology, New York University Cancer Institute, New York University School of Medicine, New York, New York, United States of America

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  • Takashi Takata mail

    To whom correspondence should be addressed. E-mail: ykudo@hiroshima-u.ac.jp (YK); ttakata@hiroshima-u.ac.jp (TT)

    Affiliation: Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan

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  • Published: September 26, 2007
  • DOI: 10.1371/journal.pone.0000944

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