LINE-1 Hypomethylation in Cancer Is Highly Variable and Inversely Correlated with Microsatellite Instability

• Marcos R.H. Estécio,

  Affiliation Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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• Vazganush Gharibyan,

  Affiliation Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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• Lanlan Shen,

  Affiliation Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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• Ashraf E.K. Ibrahim,

  Affiliation Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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• Ketan Doshi,

  Affiliation Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Rong He,

  Affiliation Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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• Jaroslav Jelinek,

  Affiliation Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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• Allen S. Yang,

  Affiliation Department of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Pearlly S. Yan,

  Affiliation Human Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America

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• Tim H-M. Huang,

  Affiliation Human Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America

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• Eloiza H. Tajara,

  Affiliation Department of Molecular Biology, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, São Paulo, Brazil

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• Jean-Pierre J. Issa

  *To whom correspondence should be addressed. E-mail: jissa@mdanderson.org

  Affiliation Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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