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Physiological Mouse Brain Aβ Levels Are Not Related to the Phosphorylation State of Threonine-668 of Alzheimer's APP

  • Yoshitake Sano ,

    Contributed equally to this work with: Yoshitake Sano, Tadashi Nakaya

    Affiliation RIKEN, Brain Science Institute, Behavioral Genetics, Wako, Japan

  • Tadashi Nakaya ,

    Contributed equally to this work with: Yoshitake Sano, Tadashi Nakaya

    Affiliation Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan

  • Steve Pedrini,

    Affiliation Farber Institute for Neurosciences of Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

  • Shizu Takeda,

    Affiliation RIKEN, Brain Science Institute, Behavioral Genetics, Wako, Japan

  • Kanae Iijima-Ando,

    Affiliations Farber Institute for Neurosciences of Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

  • Koichi Iijima,

    Affiliations Farber Institute for Neurosciences of Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

  • Paul M. Mathews,

    Affiliation Dementia Research Program, The Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America

  • Shigeyoshi Itohara,

    Affiliation RIKEN, Brain Science Institute, Behavioral Genetics, Wako, Japan

  • Sam Gandy ,

    To whom correspondence should be addressed. E-mail: samgandy@earthlink.net (SG); tsuzuki@pharm.hokudai.ac.jp (TS)

    Affiliation Farber Institute for Neurosciences of Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

  • Toshiharu Suzuki

    To whom correspondence should be addressed. E-mail: samgandy@earthlink.net (SG); tsuzuki@pharm.hokudai.ac.jp (TS)

    Affiliation Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan

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