Peripheral Nerve Injury Is Associated with Chronic, Reversible Changes in Global DNA Methylation in the Mouse Prefrontal Cortex

• Maral Tajerian ,

  Contributed equally to this work with: Maral Tajerian, Sebastian Alvarado

  Affiliations Alan Edwards Centre for Research on Pain, Faculty of Medicine, McGill University, Montreal, Canada, Department of Neurology and Neurosurgery, McGill University, Montreal, Canada

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• Sebastian Alvarado ,

  Contributed equally to this work with: Maral Tajerian, Sebastian Alvarado

  Affiliations Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada, Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, Canada

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• Magali Millecamps,

  Affiliations Alan Edwards Centre for Research on Pain, Faculty of Medicine, McGill University, Montreal, Canada, Faculty of Dentistry, McGill University, Montreal, Quebec, Canada

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• Pascal Vachon,

  Affiliation University of Montreal, Department of Veterinary Biomedicine, St-Hyacinthe, Quebec, Canada

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• Cecilia Crosby,

  Affiliations Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada, Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, Canada

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• M. Catherine Bushnell,

  Affiliations Alan Edwards Centre for Research on Pain, Faculty of Medicine, McGill University, Montreal, Canada, Department of Anesthesiology, McGill University, Montreal, Canada, Department of Neurology and Neurosurgery, McGill University, Montreal, Canada, Faculty of Dentistry, McGill University, Montreal, Quebec, Canada

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• Moshe Szyf ,

  * E-mail: moshe.szyf@mcgill.ca (MS); laura.s.stone@mcgill.ca (LS)

  Affiliations Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada, Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, Canada

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• Laura S. Stone

  * E-mail: moshe.szyf@mcgill.ca (MS); laura.s.stone@mcgill.ca (LS)

  Affiliations Alan Edwards Centre for Research on Pain, Faculty of Medicine, McGill University, Montreal, Canada, Department of Anesthesiology, McGill University, Montreal, Canada, Department of Neurology and Neurosurgery, McGill University, Montreal, Canada, Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada, Faculty of Dentistry, McGill University, Montreal, Quebec, Canada

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