CK2-Mediated Hyperphosphorylation of Topoisomerase I Targets Serine 506, Enhances Topoisomerase I–DNA Binding, and Increases Cellular Camptothecin Sensitivity

Open Access

Peer-reviewed

Research Article

Keya Bandyopadhyay,

Affiliation Torrey Pines Institute for Molecular Studies, San Diego, California, United States of America
⨯
Pingchuan Li,

Affiliation Torrey Pines Institute for Molecular Studies, San Diego, California, United States of America
⨯
Ruth A. Gjerset

* E-mail: rgjerset@tpims.org

Affiliation Torrey Pines Institute for Molecular Studies, San Diego, California, United States of America
⨯

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Phosphorylation
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Serine
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Breast cancer
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Lung and intrathoracic tumors
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Prostate cancer
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Cancer treatment
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Head and neck cancers
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Cancers and neoplasms
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