Angiotensin II Reduces Cardiac AdipoR1 Expression through AT1 Receptor/ROS/ERK1/2/c-Myc Pathway

Li Li; Zhi-Guo Zhang; Hong Lei; Cheng Wang; Li-Peng Wu; Jin-Yu Wang; Feng-Ying Fu; Wei-Guo Zhu; Li-Ling Wu

doi:10.1371/journal.pone.0049915

Loading metrics

Open Access

Peer-reviewed

Research Article

Angiotensin II Reduces Cardiac AdipoR1 Expression through AT1 Receptor/ROS/ERK1/2/c-Myc Pathway

Li Li ,

Contributed equally to this work with: Li Li, Zhi-Guo Zhang

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China
⨯
Zhi-Guo Zhang ,

Contributed equally to this work with: Li Li, Zhi-Guo Zhang

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China
⨯
Hong Lei,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China
⨯
Cheng Wang,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China
⨯
Li-Peng Wu,

Affiliation Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
⨯
Jin-Yu Wang,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China
⨯
Feng-Ying Fu,

Affiliation Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Beijing, China
⨯
Wei-Guo Zhu,

Affiliation Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
⨯
Li-Ling Wu

* E-mail: pathophy@bjmu.edu.cn

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China
⨯

Angiotensin II Reduces Cardiac AdipoR1 Expression through AT1 Receptor/ROS/ERK1/2/c-Myc Pathway

Li Li,
Zhi-Guo Zhang,
Hong Lei,
Cheng Wang,
Li-Peng Wu,
Jin-Yu Wang,
Feng-Ying Fu,
Wei-Guo Zhu,
Li-Ling Wu

x

Published: January 22, 2013
https://doi.org/10.1371/journal.pone.0049915

Viewed

Cited

Saved

Discussed

Powered by Altmetric

Questions or concerns about usage data? Please let us know.

Print

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Adiponectin
Is the Subject Area "Adiponectin" applicable to this article?

Thanks for your feedback.
Cardiomyocytes
Is the Subject Area "Cardiomyocytes" applicable to this article?

Thanks for your feedback.
Cardiac hypertrophy
Is the Subject Area "Cardiac hypertrophy" applicable to this article?

Thanks for your feedback.
Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
Heart
Is the Subject Area "Heart" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.