Oncogenic Kit Triggers Shp2/Erk1/2 Pathway to Down-Regulate the Pro-Apoptotic Protein Bim and to Promote Apoptosis Resistance in Leukemic Cells

Open Access

Peer-reviewed

Research Article

Dorothée Selimoglu-Buet,

Affiliation Institut Curie, Inserm-U830, Paris, France
⨯
Isabelle Gallais,

Affiliation Institut Curie, Inserm-U830, Paris, France
⨯
Nicole Denis,

Affiliation Institut Curie, Inserm-U830, Paris, France
⨯
Christel Guillouf,

Affiliation Institut Curie, Inserm-U830, Paris, France
⨯
Françoise Moreau-Gachelin

* E-mail: framoreau@curie.fr

Affiliation Institut Curie, Inserm-U830, Paris, France
⨯

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Apoptosis
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Leukemia
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Phosphorylation
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Cancer treatment
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Oncogenic signaling
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Flow cytometry
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Signal inhibition
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Antibody therapy
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