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Aquaporin-1 Translocation and Degradation Mediates the Water Transportation Mechanism of Acetazolamide

  • Jianzhao Zhang ,

    Contributed equally to this work with: Jianzhao Zhang, Yu An

    Affiliations State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China, Institute of Systems Biomedicine, Peking University, Beijing, China

  • Yu An ,

    Contributed equally to this work with: Jianzhao Zhang, Yu An

    Affiliations State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China, Institute of Systems Biomedicine, Peking University, Beijing, China

  • Junwei Gao,

    Affiliation State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China

  • Jing Han,

    Affiliations State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China, Institute of Systems Biomedicine, Peking University, Beijing, China

  • Xueyang Pan,

    Affiliations State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China, Institute of Systems Biomedicine, Peking University, Beijing, China

  • Yan Pan,

    Affiliations State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China, Institute of Systems Biomedicine, Peking University, Beijing, China

  • Lu Tie,

    Affiliations State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China, Institute of Systems Biomedicine, Peking University, Beijing, China

  • Xuejun Li

    lixj@bjmu.edu.cn

    Affiliations State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China, Institute of Systems Biomedicine, Peking University, Beijing, China

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