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Correction: Zonisamide Enhances Neurite Elongation of Primary Motor Neurons and Facilitates Peripheral Nerve Regeneration In Vitro and in a Mouse Model

  • Hideki Yagi,
  • Bisei Ohkawara,
  • Hiroaki Nakashima,
  • Kenyu Ito,
  • Mikito Tsushima,
  • Hisao Ishii,
  • Kimitoshi Noto,
  • Kyotaro Ohta,
  • Akio Masuda,
  • Shiro Imagama,
  • Naoki Ishiguro,
  • Kinji Ohno
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Fig 4 is incorrect. The authors have provided a corrected version here.

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Fig 4. Zonisamide rescues cell death due to oxidative stress.

Primary motor neurons in DMEM/F12 with 0.5% FBS were treated with variable concentrations of zonisamide. After 1 h, cells were exposed to 100 μM hydrogen peroxide (H2O2) for 24 h. The number of viable cells was estimated by the MTS assay and was normalized to that without H2O2 (control). Mean and SE are indicated (n = 6). *p < 0.05 by one-way ANOVA followed by Tukey HSD.

https://doi.org/10.1371/journal.pone.0148470.g001

Reference

  1. 1. Yagi H, Ohkawara B, Nakashima H, Ito K, Tsushima M, Ishii H, et al. (2015) Zonisamide Enhances Neurite Elongation of Primary Motor Neurons and Facilitates Peripheral Nerve Regeneration In Vitro and in a Mouse Model. PLoS ONE 10(11): e0142786. pmid:26571146