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Correction: Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats

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There are errors in the title and legend of Fig. 1. The title should read “Weight gain in rats during dietary supplementation period.” In the legend, “(63 ± 4 g initial weight)” should read “(140 ± 11.35 g initial weight).” Please view the correct Fig. 1 title and legend here.

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Fig 1. Weight gain in rats during dietary supplementation period.

Growth during a 16-day period in rats (140 ± 11.35 g initial weight) fed equivalent daily amounts of a lactalbumin control diet with no added cholesterol (CNC); a lactalbumin control diet with 2% added cholesterol (CC); a diet containing 50% protein from cooked sea cucumber meal (CS50); one containing 50% protein from oven-cooked sea cucumber (OS50); or one containing 50% protein from lyophilized washed sea cucumber meal (LWS50). Values are means ± SD, N = 5.

https://doi.org/10.1371/journal.pone.0118525.g001

Additionally, the following information is missing in the legend for Fig. 2: Lowercase “a” with an arrow indicates example of steatosis. Please view the complete, correct Fig. 2 legend here.

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Fig 2. Photomicrographs (A-O) of livers from rats fed control cholesterol-free [CNC] or cholesterol supplemented [CC] diets or cholesterol supplemented experimental diets containing sea cucumber (I. badionotus) meal [LWS50, CS50, OS50] for 16 days.

Sections A, D, G, J and M were stained with hematoxylin / eosin (H&E); B, E, H, K and N were stained with periodic acid-Schiff stain (PAS) and C, F, I, L and O were stained with Oil Red O. Magnification was 40X for H&E and PAS and 10X for Oil Red O. Consumption of sea cucumber limited the effects of dietary cholesterol on liver lipid deposition. CNC (A, B & C), no steatosis; CC (D, E & F), severe microvesicular steatosis; LWS50 (G. H & I), minor steatosis; CS50 (J, K & L) severe microvesicular steatosis; OS50 (M,N & O) minor steatosis with scattered lipid microvesicles. Lowercase "a" with an arrow indicates example of steatosis.

https://doi.org/10.1371/journal.pone.0118525.g002

There are two errors in the footnotes for Table 3. For footnote 2, “CC = Control with 1% cholesterol” should read “CC = Control with 2% cholesterol.” For footnote 4, “Initial weight = 140±1135 g wet weight” should read “Initial weight = 140±11.35 g wet weight.” Please view the corrected Table 3 here.

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Table 3. Growth performance in rats fed diets containing sea cucumber meals during a 16-day experimental period.

https://doi.org/10.1371/journal.pone.0118525.t001

Additionally, there is an error in the footnotes of Tables 4, 5, 7, and 8. “CC = Control with 1% cholesterol” should read “CC = Control with 2% cholesterol.” Please view the corrected Tables 4, 5, 7, and 8 here.

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Table 4. Serum total triglycerides (Tg), total cholesterol (TC) and lipoproteins (LDL and HDL) levels, and the atherogenic index (AI) in rats fed a control or experimental diet containing sea cucumber (I. badionotus) meal.

https://doi.org/10.1371/journal.pone.0118525.t002

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Table 5. Liver total triglycerides (Tg), total cholesterol (TC) and total lipids (TL) levels in rats fed a control or experimental diet containing sea cucumber (I. badionotus) meal.

https://doi.org/10.1371/journal.pone.0118525.t003

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Table 7. Fatty acid methyl ether (FAME) concentration in livers from rats fed control and experimental diets.

https://doi.org/10.1371/journal.pone.0118525.t004

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Table 8. Degree of steatosis in the livers of rats fed a control or experimental diet containing sea cucumber (I. badionotus) meal.

https://doi.org/10.1371/journal.pone.0118525.t005

Reference

  1. 1. Olivera-Castillo L, Davalos A, Grant G, Valadez-Gonzalez N, Montero J, Barrera-Perez HAM, et al. (2013) Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats. PLoS ONE 8(11): e79446. pmid:24260223