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Open Access

Correction

Correction: Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells

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There is an error in in Figure 3. Incorrect pictures were erroneously used in Figure 3A. Please see the corrected Figure 3 here.

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Figure 3. Inhibition of ERK phosphorylation or FOXM1 significantly decreased both migration and invasion of GRB7-overexpressing ovarian cancer cells.

OVCA433 cells with stable expression of GFP/GRB7 (OVCA433-GRB7) were treated with DMSO as control, Thiostrepton (20 µM), PD98059 (20 µM) and U0126 (10 µM) for 6 hours and were analyzed by (A) Transwell cell migration assay. The representative pictures and bar chart showed significant reduction in the number of migratory cells through Matrigel-coated membrane in OVCA433-GRB7 cells treated with Thiostrepton, PD98059 and U0126 than DMSO control (*P<0.02, Student t-test) at 8-hour; (B) Transwell cell invasion assay. The representative pictures and bar chart showed significant reduction in the invasion rate in OVCA433-GRB7 cells treated with Thiostrepton, PD98059 and U0126 when compared with DMSO control (*P<0.05, Student t-test) at 15-hour.

https://doi.org/10.1371/journal.pone.0110304.g001

Reference

  1. 1. Chan DW, Hui WWY, Cai PCH, Liu MX, Yung MMH, et al. (2012) Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells. PLoS ONE 7(12): e52578

Citation: The PLOS ONE Staff (2014) Correction: Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells. PLoS ONE 9(10): e110304. https://doi.org/10.1371/journal.pone.0110304

Published: October 6, 2014

Copyright: © 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.