1. Novel Bespoke Models of Consumption and Production

Additive manufacturing techniques offer the promise of cheap, local, low volume production. One of the expectations of this technology is that it could allow consumers to design, customise and manufacture personalised items, creating an industry for bespoke manufacturing and open source design [24]. While 3 D printers could potentially follow the PC in moving from industry to the home [25], there is a real opportunity for businesses to create local manufacturing services to support this new model of consumption. The technology also offers enhancement of consumer choice through making items available in the long tail [26], [27] of low demand products at low cost to the consumer compared to standard manufacturing. Additive manufacturing could offer sustainability benefits by reducing energy used in distribution by shrinking distribution chains and limiting waste from warehousing and overproduction. It could also avoid some of the waste inherent in subtractive manufacturing processes. However, the powders and polymers used in additive processes are often hazardous, come with embedded energy and require their own distribution networks, and users may print unneeded items on a whim, creating a new waste stream. Concerns arise about controlling the standard of items manufactured from blueprints available on the web, and where liability rests in the case of product failure. Controlling intellectual property presents a challenge when items can easily be rendered in CAD blueprints from a picture; as will controlling the manufacture of illegal or controlled items or their parts [28].

Science and technology challenges:

• Assessing the net impact of bespoke manufacturing on the economy, employment and length of the supply chains
• Conceiving new models for resource use efficiency, including the reduction of waste after use and during production, and minimisation of embedded energy and raw materials
• Developing appropriate Intellectual Property Rights and standards
• Understanding possible changes in digital retail and manufacturing, including issues such as liability and safety
• Understanding localised mass customisation and the actual effect on business models

2. Innovation: The Role of Government

A key function of government is correcting market failures, with respect to which, an important activity is to generate an environment that encourages innovation to the benefit of businesses, consumers and society. Government needs to work in concert with both industry and academia to stimulate, support and maintain a framework for innovation, including the innovations sought to deliver public as well as private goods [29], [30]. The exploitation of public data and greater dissemination of the results of publicly funded research also have an important role to play. In particular, while private sector R&D can drive incremental and sometimes radical innovation, Government investment in research is essential to support transformational innovation [31]. Silicon Valley’s apparently joined-up innovation ecosystem, involving clusters of related industries, seems to exemplify a successful model, but the UK is not California and we need our people to understand and support the conditions for successful innovation here. Governments cannot create new clusters [32], but can encourage new collaboration and remove the obstacles that inhibit clusters from growing.

Science and technology challenges:

• Communicating the benefits and risks of innovations, to achieve wide understanding and informed choice
• Understanding, developing and refining national systems of innovation, including a framework and standards for promoting innovation and Government procurement
• Ensuring innovation systems support societal as well as private objectives and deliver on issues such as ICT and social inclusion, the protection of ecosystem services, carbon reduction and antibiotic resistance
• Ensuring innovation systems accelerate radical as well as incremental innovation
• Developing a greater understanding of what delivers transformational change

3. Energy Resilience and Low Carbon Industry

The electricity regulator Ofgem estimates that £200 billion of investment in energy infrastructure will be required over the coming decade, to decarbonise the electricity grid and transform energy use [33]. Historically, the UK has invested in large-scale centralised electricity supply, with fewer than sixty large power stations. This is however changing. A large-scale supply will still be needed, which is likely to include offshore wind and nuclear power. However, renewable energy is often at smaller scales and more distributed (e.g. building-integrated solar photovoltaics and renewable heat grids) and energy networks will increasingly mesh with IT networks, through smart metering and other information technology [34]. Web-based crowd-funding platforms could transform energy investment models, opening up the energy market to new entrants, including co-operatives and community schemes (e.g. Abundance Generation https://www.abundancegeneration.com/and Trillion Fund http://www.trillionfund.com). Meeting carbon targets will require a fundamental look at how we use energy too, with transport networks and land-use planning influenced by the need to make smarter use of energy [35]. Encouraging this shift requires changing government policy, including better incentives for innovation in microgeneration networks as well as generation technologies; a more strategic land-use planning system for energy infrastructure; a move beyond energy efficiency to incentivise demand management measures in transport, housing and industry; and the encouragement of new entrants into energy investment, including local authorities, co-operatives and the ICT sector.

Science and technology challenges:

• Incentivising low carbon technologies and production
• Presenting the case for planning permission/consent for energy infrastructure
• Promoting interdependency in decision making with other areas, e.g. transport, housing
• Incentivising investment in the demonstration of technologies
• Accommodating both centralised energy systems and distributed generation (see also next section)

4. Policies for Whole Energy Systems

As an era of dependence on fossil fuels gives way to emerging efforts to transition to a low carbon economy [36] (also see previous section), energy systems are becoming more distributed and interconnected [37] and such trends stand to increase substantially over the next few decades. Centralised energy supply from large power plants is increasingly accompanied by smaller scale production (e.g. renewables, micro-generation) and storage. Energy demand reduction and efficiency measures need to be taken more seriously, giving a wider range of actors (including consumers and households) and technologies (e.g. smart devices) a more active role [38]. There must also be more focus on demand shifting to allow better use of the dynamic supply created by renewable energy sources [39]. Energy security, once a predominately national concern, becomes one of interdependencies between nation states. Under these conditions a compartmentalised policy approach – that focuses on specific energy technologies, sectors, and parts of the system in isolation – becomes outmoded. Secure, affordable and environmentally sustainable energy futures require a systems approach to energy policy, and a policy for the whole UK energy system covering generation, transmission, distribution and use. This will involve integrated and joined-up policies that account for interconnections across the system and scales of decision-making. This in turn depends on developing whole systems energy science that understands system-wide interconnections and interdependencies through linking physical, engineering and social scientific analyses [40].

Science and technology challenges:

• Developing capabilities in interdisciplinary whole systems energy science, including new methods, approaches and analytical tools
• Understanding the implications of a whole systems approach for structuring, governing, regulating and managing the energy system and low carbon transitions
• Devising mechanisms to facilitate integrated grid management systems and utilise SMART technologies
• Determining the economic dimensions and market implications of a more distributed energy system
• Developing and harnessing robust evidence of the social and political dynamics of energy transitions in tackling difficult decisions around energy systems

5. Energy and Transport Infrastructure for Changing Work and Living Patterns

Work and living patterns are changing due to increased usage of information and communications technologies (ICT). Individuals now have more flexibility over where they live and work. These changing patterns, and how they impact on energy and transport infrastructure, need to be better understood to inform policy decisions. Benefits of these changes range from reducing peak demand in capacity-stricken transport systems, reducing associated negative environmental impacts [41], [42], more efficient business organisation and improved work-life balance for workers. However, these shifting patterns could significantly change the expected demand for services provided by energy, transportation and also ICT infrastructure. This is an issue for the UK as it has many infrastructure challenges to tackle in the coming decades, particularly with regard to climate change [43]. Emissions may shift from transport to home energy demand or may re-emerge in other parts of the system. More robust quantification of these changing patterns are needed. The ‘behavioural turn’ in policy making [44], suggests that policy responses will be more effective if they incorporate understanding of the drivers that influence behavioural change [45], coupled with understanding of the long-term evolution of energy, transport and ICT systems, and their changing relationships to the environment, the economy and society.

Science and technology challenges:

• Measuring, understanding and quantifying infrastructure demand changes on energy, transport and ICT
• Identifying opportunities that could arise from changes in infrastructure demand, such as in ICT reducing transportation demand
• Understanding the interactions of the energy, transport, ICT and social systems and how they influence the evolution of the systems
• Understanding how changes in energy, transport and ICT systems affect total emissions
• Identifying drivers that will influence long-term behaviour change, utilising them for societal advantage

6. Feeding a Larger and Wealthier Global Population Sustainably and Equitably

Today nearly a billion people suffer from calorie hunger and a further billion are malnourished [46]. Food demand will increase dramatically driven both by growing population but also by higher average wealth leading to demands for more resource intensive diets. Possibly 60–70% more food will be needed by mid-century to avoid politically destabilising food price increases [46]. Addressing famine and malnutrition are ethical priorities as well as essential for politico-economic stability. Food production is also threatened by greater competition for water, land, energy and other inputs, and well as the effects of climate change. Agriculture is already a major agent of environmental degradation, undermining our future capacity to feed the global population, as well as a significant driver of land use change, nitrate pollution and greenhouse gas emissions. There is an urgent need to make food production more environmentally sustainable; enhancing and not degrading natural capital. The magnitude of the challenges ahead strongly suggests that action is required simultaneously on all parts of the food system – to produce more food, consume less resource-intensive food types, reduce waste and improve the governance and efficiency of the food system [47]. Though bringing more land into agriculture would increase food production, the advantages are outweighed by its major environmental consequences (including greenhouse gas emissions and loss of biodiversity) [48]. Sustainably increasing productivity (sustainable intensification) is thus a key response [49].

Science and technology challenges:

• Reducing waste and improving efficiency in storage and distribution
• Producing more food from the same area of land with fewer negative environmental effects
• Increasing the efficiency with which water, energy, fertiliser and other agricultural inputs are used whilst also increasing agricultural outputs
• Addressing the food needs of “mega-cities”, especially in the tropics
• How choice of diets could be influenced towards those with less environmental (and health) impact
• Creating governance frameworks for the global food system to promote food security

7. Sudden Environmental Change

There are growing concerns about the accelerating rate of environmental change as a result of continuing population growth and resource consumption [50] Climate change represents an unprecedented and sudden change relative to climate variability over the last 12000 years, posing considerable challenges for risk management and public action with a consequent need for transformational adaptation [51]. How we rapidly and deliberately transform systems and society in order to avoid the long-term negative consequences of sudden environmental change, however, remains a considerable challenge [52]. Changes in the climate system are occurring at the same time as other environmental changes, such as biodiversity loss and ocean acidification. A range of planetary boundaries has therefore been proposed [53] that define the ‘safe operating space’ for humanity with respect to the Earth system. There is, in addition, an increasing awareness that once a critical point is reached, positive feedbacks in the system may propel change towards an alternative state [54]. A number of such critical points, sometimes referred to as tipping points, have been identified, including the loss of Arctic summer sea-ice, reorganisation of the Atlantic thermohaline circulation and dieback of the Amazon forest. The risks and economic consequences (and potential benefits) of such tipping points remain difficult to assess [55].

Science and technology challenges:

• Identifying when we should respond to the risk or opportunity of extreme environmental changes
• Developing an appropriate policy approach for low probability but high impact events
• Learning from past high impact singular events and examine whether they were predicted by models in use at the time
• Understanding public perception of risks and how these can be taken into account in decision-making
• Encouraging researchers to accept more openly the limitations of their research and models, and enhancing capability in communicating uncertainty, ambiguity, complexity and ignorance

8. Climate Change Adaptation

Societies adapt pragmatically to variations in current weather. But climate change presents adaptation challenges of a different order as extreme events become more frequent and widespread. Building resilience to climate change requires actions across every sector – from agriculture to health, from business to infrastructure – and the interactions between them. Actions are likely to have a net cost, compounded by the fact that there is no defined adaptation end point. This creates a significant institutional and societal challenge, locally and nationally [56], [57] with an outstanding need to build appropriate governance systems and supporting analysis at different scales. The UK Climate Projections [58] provide readily accessible probabilistic projections for future climate. But the first Climate Change Risk Assessment [59] illustrates the problems of dealing with endemic uncertainty and complexity not least in terms of the interrelationship between on-going environmental, economic, and societal changes and climate change; see also the National Adaptation Programme [60]. There remains an urgent need for institutions to build adaptive capacity into every element of their responsibilities with a cross-sectoral approach to policymaking and implementation [56]. Effective institutional responses will build flexibility into decisions such that future as yet unknown climate outcomes can be responded to in a timely and cost-effective manner while maintaining a positive contribution to ecosystem services.

Science and technology challenges:

• Identifying governance system options that could enable effective local and national adaptation responses
• Identifying and defining climate adaptation priorities, e.g. temperature extremes or longer-term temperature changes
• Analysing the full range of the local impacts of climate hazards and their interaction across different sectors to support planning at the local level
• Understanding the potential consequences of series of different climate related hazards
• Applying broader and more sophisticated systems thinking to analysis and policy-making that reflect the complex interactions between and within environmental, economic and social systems

9. Climate Geo-engineering and Climate Change

Geo engineering [61] refers to deliberate, large-scale intervention in the global natural systems that determine climatic patterns. Concerns about whether we can mitigate climate change through emission reduction sufficiently fast, or adapt to temperature changes in the higher of predicted levels, have led to consideration of such technologies as an alternative approach to mitigation of climate change effects. Currently identified possible interventions [61] include direct atmospheric modification (such as increasing cloud formation, thereby raising planetary albedo), atmospheric/oceanic (ocean fertilisation) or atmospheric/land surface (surface albedo modification) interactions, as well as manipulation of the earth’s incoming solar irradiance in outer space. A subset of climate engineering is the so-called Negative Emissions Technologies [61], [62]; NETs are intended to remove significant amounts of radiative forcing gases (usually CO₂) from the atmosphere and include such diverse methodologies as ocean fertilisation and the large-scale pyrolysis of vegetable matter, with CO₂ capture from the flue gases, followed by its geological sequestration and the burial of the remaining char in soils, which can lock up its contained carbon for many years. All geo-engineering technologies need to be assessed in terms of energy use, economic costs, social acceptability and environmental consequences; they may exacerbate climate risks rather than reducing them if not carefully managed [63]. In consequence, a set of principles for undertaking research into geoengineering options [64] was discussed and endorsed by the House of Commons in a recent report [65] calling for

1: Geoengineering to be regulated as a public good

2: Public participation in geoengineering decision-making

3: Disclosure of geoengineering research and open publication of results

4: Independent assessment of impacts

5: Governance before deployment

Making these principles operable will require research and testing.

Science and technology challenges:

• Identifying the potential impacts and unintended consequences of the various technologies
• Identifying and addressing the implications for international agreements
• Assessing the scalability, rollout potential, effectiveness and reversibility issues associated with each of the technologies
• Identifying the social impact and acceptability of the price of carbon that is required to ensure that these approaches are cost effective
• Dual use dilemma and other risks, but also whether these technologies could provide opportunities for other public benefits

10. Integrated (Multi-functional) Land-use Planning

Robust land use policies and delivery mechanisms are vital to the economy, for food, commodity and energy production and for the use of land for infrastructure, housing, tourism and recreation. UK approaches have traditionally focussed on single purposes, often to enhance delivery of one ecosystem service, such as food provision, to the detriment of others [66]. From the late 1940s, the UK focussed on maximising production, but while productivity increased other ecosystem services declined, particularly biodiversity and the quality of air, water and soil [67]. Population increase, climate change and economic growth, taken with the finite nature of land and natural resources, present a growing concerns for policy makers as to the continued delivery of a range of ecosystem services [68]. The food, energy, environment “trilemma” for land use, if poorly handled, may lead to further ecosystem degradation, increasing energy consumption and missed opportunities (e.g. to introduce lower carbon feedstocks, optimise food production at less ecosystem detriment or incorporate biofuels into land allocation strategies to reduce fossil fuel use [69]). ‘Multi-functional’ approaches to land use propose balancing competing demands across wide areas (landscape scale) to ensure multiple ecosystem services are delivered. Emerging new methodologies to measure and value benefits provided by environmental assets could improve policy decisions about species, habitat and ecosystem conservation or conversion [70]. Such evaluations bring social & personal, as well as economic, values into focus, necessitating new approaches to engaging the public about their environment and in how it is used.

Science and technology challenges:

• Assessing the validity and usability of different approaches to valuing ecosystem services
• Developing scenarios for addressing the land use ‘trilemma’
• Evaluating approaches to trading off and optimising between ecosystem services in resource allocation decisions
• Improving the ability to analyse risk and opportunity in resource and service allocation decisions
• Developing and testing methods to support resource allocation conflict resolution

11. Novel Substances in the Environment

As technologies develop there is a need to effectively identify and assess previously unidentified risks [71]. Communication and regulatory challenges are complicated by incomplete evidence bases and the need to balance opportunity and caution when the impact of, or exposure to, a substance is unknown [72], [73]. Development should be socially responsible and use appropriate regulatory tools [74]. Governments rely on methods (e.g. PESTLE analysis, considering the Political, Environmental, Societal, Technological, Legal and Economic impacts) to support responsible decision-making [75], but in industry less encompassing approaches are used. Technological advances mean that the impacts of new substances (or technologies) may not be characterised until they are in widespread use [76], further complicating regulatory decisions, e.g. nanoparticles used to scavenge soil contaminants are now known to have additional effects. Normally assessors use a dose-response to identify hazards, but this may be misleading without understanding how the target organism processes the substance (e.g. accumulation, metabolism or excretion). Researchers may assume a linear or threshold response and design experiments accordingly, thereby missing non-standard (e.g. U shaped) responses [77]. Some adverse effects may not be identified by standard test regimes if they occur at low doses but may be of concern where receptors are exposed to the substance by many routes or when a number of substances have similar affects (e.g. endocrine disrupting chemicals [78]). Such limitations affect the appropriateness of adopting governance principles, such as ‘substantive equivalence’ or ‘precautionary principle’.

Science and technology challenges:

• Establishing timely risk identification and effective management responses to emerging novel substances, also determining the acceptable levels of risk
• Developing and promoting a balanced, adaptive, responsible approach to the governance of innovation which considers both risks and benefits of technological advances
• Identifying opportunities for the exploitation of novel substances, such as the use of scavenging nanoparticles in remediation
• Understanding and measure dose response curves in analysis, and deal with the consequences when things go wrong
• Explaining and ensuring the context specific, appropriate application of risk frameworks

12. Meeting Long-term Skills Requirements

Concerns about meeting long-term skills requirements have been persistent; underpinned, first, by difficulties in predicting and anticipating demand, and second, by challenges to meeting demand through UK-based education and training as well as absorption of skills available from other countries. In the first case, predicting and anticipating demand for skills is beset by inherent uncertainties: it is difficult to know what skills sets will be needed by society in future production or in the provision of future services, and how these skills sets might be changed (or even eliminated) by advances in technology. In the second case, meeting demand for skills through education, training and absorption is no less difficult, requiring greater understanding about and enhancement of learning, skills development, and national absorptive capacity. Alongside cultivating and maintaining high levels of scientific literacy at national level, individuals should also be supported in ‘learning to learn’ [79] (i.e. learning through applying knowledge and skills flexibly in a variety of roles, and treating learning as a life-long endeavour) and be empowered to make proactive careers decisions. This is likely to require even closer collaboration between government, industry and the education sector, working through formal and informal channels of education. In relation to the last, more strategic research and systematic evaluation of initiatives are required to help build on knowledge that is being generated from experience [80].

Science and technology challenges:

• Improving methods for anticipating demand,
• Developing enabling frameworks to help individuals to make proactive careers decisions coupled with improving individual capacity for learning and acquisition of skills
• Understanding and enhancing national absorptive capacity for skills from elsewhere
• Maintaining long-term scientific literacy (at national and individual level)
• Providing a strategic evaluation of interventions

13. New Means of Delivering Learning

The delivery of education using the Internet promises to bring learning opportunities to more people than ever before, potentially drawing new audiences from across the world, whilst also enabling learners to have greater control over when and how they learn. Massive open online courses (MOOCs), in particular, are growing rapidly in popularity. This expansion in e-education, however, is not without challenges. On a practical level, sustainable business models for commercialising MOOCs, encompassing systems for verification of credentials, assessment and certification, have yet to be developed [81]. Whilst it is hoped that specially-prepared lectures and online content may drive improvements in teaching and ensure a high quality learning experience for more learners, issues around quality assurance and ways of accessing reliably-verified information have yet to be resolved. Research is also needed to help understand the potential of e-education within both formal and informal education contexts, and how this can be exploited to enhance learning. As yet, development of good practice is unsystematic. Little is known about the relative efficacy of widespread e-education, particularly as it relates to the social engagement of learners, which is thought to be valuable in its own right as well as being an important factor underpinning motivation and performance [82], [83]. Widespread access itself is also predicated on the deployment of super-high-speed broadband. The challenge of providing this necessary technological infrastructure poses questions for democratic access to information and learning.

Science and technology challenges:

• Providing reliable verification of information (quality assurance) and access to reliably-verified information
• Developing systems for verification of credentials, assessment and certification, particularly for distance learning
• Developing sustainable business models for MOOCs and other novel approaches
• Presenting scientific information in ways that are accessible and intelligible to non-scientific audiences
• Understanding social engagement through educational practises and how its benefits may be captured in e-learning contexts

14. Assessing the State of the Nation

Whilst policy-makers’ desire to assess the overall “state” of the nation is not in itself novel, many workshop attendees felt, in light of a persistent lack of economic growth, that the coming years would witness a renewed imperative to find more comprehensive measures of ‘success’ than simple Gross Domestic Product (GDP). According to a 2012 House of Commons Public Administration Select Committee Report [84], the incumbent UK Government has itself identified six ‘strategic aims’ as crucial to the advancement of the national interest: (1) “a free and democratic society, properly protected from its enemies”; (2) “a strong, sustainable and growing economy”; (3) “a healthy, active, secure, socially cohesive, socially mobile, socially responsible and well-educated population”; (4) “a fair deal for those who are poor or vulnerable”; (5) “a vibrant culture”; and (6) “a beautiful and sustainable built and natural environment”. This policy issue is therefore concerned with finding robust and appropriate measures (such as of wellbeing and happiness; see [85], [86]) of the extent to which such strategic aims are being met [see also entry 25 below – on the use of happy life expectancy as a criterion for resource allocation decisions by government]. At a more fundamental level however, it also pertains to the question of what exactly Government should be seeking to measure in the first place. Recent efforts in this direction include the UK National Ecosystem Assessment [67] and the on-going work of the Natural Capital Committee, for example their The State of Natural Capital report [70] to the Chancellor of the Exchequer.

Science and technology challenges:

• Comparing the relative strengths and weaknesses of different measures of success, productivity, happiness, wellbeing and other desirable attributes in society today
• Criteria for choosing appropriate and robust metric(s) for the measurement of national success that go beyond simple GDP
• Developing research tools and methodologies that are able to capture this/these metrics accurately
• Allocating fiscal and other resources between and within Government departments in ways that enhance the “state of the nation”
• Developing evaluative tools that will enable policy-makers to respond to data concerning the state of the nation promptly and effectively

15. System-level Vulnerabilities and Increasing Complexity

Policy has to deal with numerous multi-faceted complex issues where evidence is often fragmented, highly uncertain and comes from a range of sources [87], [88]. These situations are also notable by the many highly interrelated aspects and contested issues that arise and where deep-seated conflicts around purposes, goals and values are common. Complexity and interdependence give rise to often unpredictable ‘emergent’ outcomes, belying the single-point forecasting approaches traditionally used in developing and implementing policy and creating vulnerabilities for decision-making [89]–[91]. Yet, in the face of such profound and ubiquitous complexity and interdependency, policy still seeks to promote positive outcomes for society, the economy and the environment [87]. While systems-theory and complexity science are developing fields [88], [92], they are not widespread in policy or practice, requiring tailor-made approaches [89], [93]. Exploratory and experimental attitudes and tool-kits are required that allow us to adapt as we learn from practice and experience across many domains [90], [92]. The application of science to policy requires integration of (a) Different sources and forms of knowledge (natural science, social science and humanities, practice-based knowledge, lay knowledge, etc.) [87], [89], [93]; (b) a range of processes for acquiring, making sense of and using this evidence [91], [92]; and (c) a range of different perspectives and approaches (e.g. [94]).

Science and technology challenges:

• Developing applications of systems thinking and complexity theory for policy making
• Applying systems approaches across disciplines
• Identifying conditions under which systems may be vulnerable to failure and understanding the resilience of systems
• Understanding how to allocate resources to high impact but low probability events
• Understanding non-linear systems within a policy context (e.g. the electronically connected world)

16. National Infrastructure in a Localised and Interconnected World

Historically, the implementation of each individual infrastructure project has been treated as an isolated technical challenge, with only sufficient integration to meet the project aims. The Council for Science and Technology [95], however, recognise that, in reality, national infrastructure is better considered as a network of networks. This is reflected in the National Infrastructure Plan of 2011 and subsequent updates [43], [96] which noted that the UK’s approach to infrastructure had thus far been fragmented, adding that “opportunities to maximise infrastructure’s potential as systems of networks have not been exploited”. These infrastructure interdependencies can be physical, digital, locational or organisational and such complex systems can suffer from common mode failures or precipitate failures that ‘cascade’ from one sector to another. Planning and managing these interdependencies can increase system resilience and save engineering costs, but can concentrate risks. Reliance on digital and organisational interdependencies for the continued safe delivery of services by national infrastructure networks introduces a number of common mode failure possibilities and new vulnerabilities to attack. A balance must be struck between security and the higher levels of efficiency that smart systems allow. The emergent behaviour of complex, interconnected and interdependent systems (especially open complex adaptive systems) cannot be adequately modelled or always predicted following perturbations to any component of the system. Planning, management and policy responses therefore need to be flexible and adaptive.

Science and technology challenges:

• Enabling efficient and effective public engagement and access to information
• Understanding incentivisation, including the science of offsetting
• Improving contextualisation (science input) to inform high level decision making
• Improving understanding of how to identify at an early stage and manage emergent properties of complex systems
• Enhancing government understanding and evaluation of the validity and value of different forms of knowledge

17. Public Sector Capacity to be an Intelligent Customer of Scientific Advice

This is a different kind of issue from others addressed in this paper, but its importance comes from the way in which it addresses the effectiveness with which other issues are handled. It is also driven by the observed difficulty in having open and objective debates on the evidence surrounding socially and ethically sensitive issues, such as recreational drugs [97]. It has never been the case that all scientific advice and evidence is generated within Government. In the current context, with the current Civil Service Reform plans, and the move to open policy making [98], it is even more imperative that the public sector has the capacity and expertise to be a commissioner and customer for scientific advice, and to ensure that the scientific aspects of an issue are weighed in the balance with others. Further, the open policy making agenda will put an even higher premium on the ability to moderate an open discussion on difficult issues, where the pressure from the media is sometimes liable to drive a more knee-jerk approach. With respect to the use of scientific advice in policy making, and the development of the Science and Engineering profession in Government [99], important issues include the challenge of retaining knowledge when officials move post, and its impact on understanding; the importance of an active and reliable network of contacts in the scientific world, when an urgent issue (such as foot and mouth disease) needs to be handled; and handling the research commissioning process. Similarly, it is critical to build capability in scientists, and policy-makers (and wider constituencies) to recognise, characterise, take account of and communicate inherent uncertainties, ambiguities, complexities and knowledge gaps inherent in science and evidence.

Science and technology challenges:

• Re-evaluating the effectiveness of current structures for obtaining advice and for investing in future evidence provision through research, including whether they are understood, sufficient, and appropriate
• Developing the foresight to identify research needs of government departments (as opposed to the Research Councils & Higher Education sectors)
• Identifying an appropriate range of policy evaluation approaches and methodologies (including working outside of policy and discipline silos)
• Creating capacity for more creative thinking about ‘wicked problems’
• Developing methods for assessing the value and validity of, and for valorising, non-scientific evidence in policy making

18. Using Public Engagement to Improve Government Decision-making

Within the UK Civil Service Reform agenda [98], government is trying to develop better ways of bringing public opinion and public views into the early stages of policy development [100]. This requires a shift in the culture to empower civil servants to put forward genuine questions at an early stage for resolution to the wider public, rather than simply offering pre-prepared solutions for validation by the more usual 6–12 week public consultation process. Civil Service Reform has signalled [101] the need to change the traditional policymaking cycle in order to encompass public/stakeholder participation earlier, and to foster a greater understanding of how to frame questions that will encourage input that is relevant and timely, and therefore useable. This has highlighted the need for improved capability among policymakers in analysing and interpreting the public responses. Automated analysis tools are low in resource terms but not always deployed effectively. New dashboards are currently being rolled out in a number of Departments to monitor social intelligence, but the value of the data is often not maximised to support decision-making. Currently it is used more as a horizon-scanning tool to predict the likely reception of Departmental policies and so to inform their communications plans. There is a gap in political and social science analytical skills at the cutting edge of public engagement, most especially when social media channels are in use. This has created a risk that the dialogue and data capture methods now available are outstripping the analytical capability.

Science and technology challenges:

• Understanding how to interpret and have confidence in evidence and outcomes from public engagement
• Determining when (and when not) to engage the public
• Using crowdsourcing and social media technologies to gather public opinion and generate public discussion
• Understanding and developing responses to the internal mechanisms of policy-making that make action on social intelligence 'difficult' for policy-makers and politicians, through applying political science to develop and trial new approaches
• Developing new methodologies for government to monitor social intelligence

19. Democracy in the Digital Age

Technology is changing the way that all engagement between institutions and citizens is undertaken [102]. The first generation of digital engagement often just replicated paper forms on a website, but second-generation models are more social, more flexible and more conversational [103]. The UK Government’s Open Policymaking programme [98] has recognised this and is seeking to change practice in Whitehall and beyond. A digital approach can support good policy development in two ways: first, online engagement around policies involving science and technology will increase the ability of the public to participate in democratic discussion. Secondly, where specific exercises are planned, digital methods can expand the footprint, involving more people and broadening the conversation. However, digital routes can quickly spread misinformation that distorts or oversimplifies information, thereby undermining related policy debate. Similarly, digital media can exacerbate the problem of over-simplifying complex technological points, and can also be used to present a baseline of opinion rather than knowledge. Looking to the future, many see digital technology as much more than an alternative delivery mechanism; it is a culture and an approach. Digital media is seen as increasingly likely to dominate engagement in science policy, perhaps even becoming the primary portal for debate rather than an electronic reflection of offline activities.

Science and technology challenges:

• Identifying the issues involved in balancing the individual’s right to privacy with the use of data (public or private) for public good and approaches to resolution
• Developing criteria for balancing participation (access issue and control issue) and inclusivity (e.g. with respect to interest groups vs. other stakeholders)
• Identifying the hidden implications of search algorithms and filtering of knowledge (the geography of internet control) and finding approaches to manage them transparently
• Understanding perceptions and intentions of “transparency” and “open decision making” and how to achieve them
• Providing sufficient but not excess access to reliable information that meets the needs of individuals and social entities

20. Managing Extreme Events: Public and Private Sector Roles

Individual national governments no longer have exclusive ownership of the infrastructure and delivery mechanisms that previously provided resilience in times of environmental or social emergencies [104]. The water, food, power and transport systems are all owned by private, often global, entities that may not always share national or domestic community imperatives. The solutions to food shortages, flooding, energy outages are traditionally dependent on the co-ordinated delivery of support services and emergency plans. Since these are now effectively outsourced to private sector companies - who may need to respond to market requirements rather than urgent local needs – how can governments continue to provide the necessary duty of care to its citizens? Incidents that require manpower are still relatively simple to resolve using employees within the public sector, e.g. the army are deployed to support flood evacuations; Local Government employees can man the farm quarantine areas during animal outbreaks. Emergencies whose solution is expected to involve distribution of now privately owned assets or service delivery (e.g. energy, water, fuel) require a different form of contingency planning [105]. If the emergency is one that impacts the priority customers of the asset owners, then the two agendas are aligned. The question arises when – in the event of a collective failure, perhaps linked to an extreme weather event (sunspots, flooding and volcanic ash) – the global company has to select the countries to which it prioritises resources.

Science and technology challenges:

• Identifying social, economic and technical barriers to engagement and collaboration between organisations in the response to extreme events, especially public and private organisations, and ways to overcome them
• Identifying the distribution of collective and individual responsibilities and liabilities for emergency response and contingency planning between public and private organisations and means to share them equitably
• Assessing whether insurers could provide mechanisms for cost and benefit sharing, especially in relation to low incidence high damage emergencies
• Evaluate the implications of cost and benefit distribution for investment in infrastructure provision
• Investigate alternative business models for private sector companies which could enable them to address their responsibilities for planning for and responding to disaster situations

21. Emerging Diseases

The threats from emerging diseases across the plant and animal kingdoms are an ever-present worry with increasing human populations, increasing intensity of crop and livestock production, pressures on scarce resources, climate change and the international mobility of man, animals, plants and organic materials [106]. Just as threats to human health may come from zoonotic infections or from infectious agents that jump the species’ barriers, so might threats to the environment come from transmission of disease from domesticated to wild populations [107]. The threat is on a global scale; greater mobility, combined with changes in environment, threatens each nation. We need to understand and to anticipate the effect of environmental changes that have seen the recent appearances in the UK for example of the Schmallenberg virus or the emergence and relatively rapid spread of Chalara fraxinea as the causal agent of dieback of Ash trees in Europe [108]). We need to understand the complexities and dependencies of systems (such as agriculture and trade), looking for commonalities as well as the specificities of approaches to complex problems including better computer modelling, increased understanding of the fundamental principles of infection, transmission and species barriers, genetic and environmental factors affecting susceptibility and triggers for emergence or resurgence of disease threats. We need to make use of novel research tools both for surveillance [109], imparting information and also crowdsourcing afforded by the globalisation of access to electronic media [108], understanding not only the challenges, but also the opportunities this brings.

Science and technology challenges:

• Identifying and prioritising disease threats in plants and animals (including humans) and the effects they have on the different ecosystems (including services)
• Improve institutional risk analysis & management systems to enable better integration of early-warnings into priority setting and resource allocation within business-planning
• Understanding the mechanisms that enable diseases to jump the species barrier and how they emerge in populations
• Developing better models for understanding disease spread and control, and feed that through to the decision making process in a timely fashion
• Determining the role of social media in identifying disease outbreaks and influencing public action and perception

22. Antimicrobial Resistance and Infectious Diseases

The UK Chief Medical Officer has identified antimicrobial resistance as one of the greatest threats to modern health [110], a view shared by the World Health Assembly [111]. Antimicrobial resistance in pathogens that affect human health is an unsurprising evolutionary consequence of the prevalence of antimicrobials in human and animal populations. The rate of its development is a function of how widely they are used and to what degree in any domain where dangerous pathogens are present. The science and technology challenges related to this issue, therefore, are to be understood in the broader context of how human societies respond to any infectious disease, since pathogens will always sit in a dynamic and evolving relationship to the species they infect. Antimicrobial resistance represents a distinct policy challenge [112] only because of our failure to take account of evolutionary processes in the conduct of medical practice and the wider use of antimicrobials. This is exacerbated by trade and travel affecting the global circulation of resistant organisms. A two pronged approach is required that addresses not only the scientific, technical and industrial agenda for the prevention of infection, promotion of immunity and facilitation of diagnosis and cure, but also political, social and economic issues [113] that are fundamental to the translation of scientific discoveries into effective and sustainable practices

Science and technology challenges:

• Resolving the tension between public health requirements and personal preference
• Identifying and promote measures that prevent people from getting infectious diseases, for example avoidance and vaccinations
• Monitoring and understanding the emergence of novel infectious agents
• Identifying and promote behavioural change (misuse of antimicrobiotics) and improved diagnostics (input of genomics and proteomics) that will reduce infectious diseases
• Identifying methods to incentivise the development of novel therapeutics

23. Effective Health Systems within Finite Budgets

With an ageing population and the increase in chronic conditions like diabetes, demand for healthcare looks certain to increase [114]–[116]. Patients’ expectations of the quality of service and support that they receive will continue to be high. Scientific developments in pharmaceuticals, medical devices, imaging technologies, diagnostics and improved ICT systems will generate opportunities for improved care that are important for patients, and are areas where the UK life science community is looking to advance research and commercialisation of new products [117]. However, fiscal constraints on government spending [118] mean that budget limitations will continue to constrain what can be offered to patients via the NHS. Other types of innovation to reduce utilisation of services through better self-care or home care may generate opportunities for efficiency gains [119]. Adoption of low-cost technologies and approaches piloted around the world may also create new ways to strip out costs from current modes of service delivery. Understanding the emerging technical opportunities for healthcare innovation and the social factors that will drive future demand and utilisation of health services will be essential to allow the UK to meet its long-term policy objectives of improving health outcomes and generating a world-leading life sciences sector within a context of fiscal probity.

Science and technology challenges:

• Developing better tools for self-management for (chronic) diseases
• Improving the balance between prevention and treatment
• Understanding and managing demands for healthcare from the public
• Developing technologies that have high impact but may have low market value or relate to unfashionable areas of research
• Developing or borrowing useful low-tech solutions from around the world

24. Demographic Change

One of the most powerful levers affecting future policy is demography. It affects the provision of resources, such as food and water, services, such as health care and pensions, and has profound effects on the economy. However, the importance of demographics is frequently underestimated [120] and the accuracy of predictions often overestimated; UK demographic models from the 1980s-2000s predicted significantly lower populations in 2020 and beyond, than more recent models [121]. This, in part, is what has led to recent controversial changes to retirement and pensions planning. Several questions emerge around our concept of retirement, our knowledge of the economics and geography of changing demographics, and the role that management design and technology can play in a world where a higher proportion of older people expect to and are expected to make on-going economic contributions, possibly in part time or less heavily loaded positions [122]. There is also a growing demand on the grandparental cohort to support their working age children through babysitting and other family services, which will have important consequences for the labour force and the economy. There are challenges here for policy makers, who will have tough choices to make in the coming years.

Science and technology challenges:

• Identifying whether we should change our concepts of career structures and retirement
• Establishing whether we can accurately predict the economics of future demographic structures
• Developing technologies to enable integration of all age groups in society
• Identifying how patterns of work change as age structures change
• Identifying the impact of changing demographics on where people live

25. ‘Happy’ Life Expectancy and Government Resource Allocation Decisions

There has been increasing interest in subjective measures of health and wellbeing. Evidence showed that self-rated health predicted the likelihood of dying within a given time period [123], and also measured health in a positive sense [124]. Increased healthy life expectancy, as measured in this way, is one of the overarching outcomes in the Public Health Outcomes Framework, which sets out the government’s vision for the new public health system [125]. A utilitarian would argue that the aim of all government policies, and the organised efforts of society as a whole, should be to maximise positive wellbeing for the maximum number of people for the greatest possible length of time. Such an outcome (which for convenience could be summarised as maximising “happy life expectancy” where “happy” 'is used as a short hand for subjective wellbeing) could be measured in an analogous way to healthy life expectancy by combining population indicator(s) of wellbeing with those of life expectancy. Examples of such indicators have recently been developed by the UK Office for National Statistics (ONS), and the Organisation for Economic Co-operation and Development (OECD) recently produced a guide to measuring subjective wellbeing [126]. A measure of happy life expectancy based on this type of work could be used as a “common currency” across government, and across sectors, to compare the impact of apparently disparate policies and to inform decisions about resource allocation and prioritisation (see also section 14 above on the use wellbeing measures to assess the “State of the Nation”).

Science and technology challenges:

• Establishing the best ways for Governments to act, including to allocate public resources and encourage private action, to maximise wellbeing
• Identifying whether such policy tools would be sustainable/ethically acceptable
• Identifying how wellbeing policy objectives could be applied in different sectors of governments
• Determining which measures of wellbeing best represent actual wellbeing reliably
• Determining how to build social and political understanding and consensus around wellbeing metrics

26. Decision Making by Autonomous Systems

Technologies that operate with little or distant human control are ever more common [127]. Software that helps machines learn from their environment is rapidly increasing the intelligence of autonomous systems. These technologies promise great benefits, taking on mundane, dangerous and precise tasks. The range of applications is wide, from driverless vehicles, to automated financial trading systems, to autonomous surgical robots. Each of these applications offers diverse benefits and the challenges posed by the technology will vary between sectors [128]. The UK government promised £35 m of extra funding to this area in Autumn 2012, focusing on autonomous robot machines [129]. The UK is a global leader in the development of algorithmic software and has just finished a five-year, £50 m evaluation of opportunities in unmanned airborne vehicles. As a nation at the forefront of the development of these technologies; it is time to lead a much broader public debate about the value of these developments.

Science and technology challenges:

• Coordinating and communicating technological assessment of the resilience and safety (human, social, economic) of autonomous systems
• Exploring the social factors that enable trust and or support trustworthiness of autonomous systems, particularly in respect of health, social care and financial systems
• Identifying context-specific factors that affect the reliability of a system
• Identifying the principles and criteria to establish clear instructions for when and how humans should intervene in autonomous systems
• Identify means to enable public discussion of the ethical and technical issues involved in automating decisions

27. Managing Demand for Motorised Personal Road Transport

Road transport plays a key role in economic, health and environmental aspects of society. Improving its infrastructure and demand management will result in an increase in road safety and transport efficiency, as well as in a reduction of travel times, congestion, transport costs and carbon emissions [130], [131]. The development of Intelligent Transport Systems (ITS) will provide drivers with real-time information to improve decision-making and facilitate road network management [132], [133]. Examples of such real-time communication could include congestion reports, route guidance, lane departure warnings, blind spot warnings and adaptive cruise control. While most of the technology required for the implementation of traveller information systems already exists, more research is needed on how road users will react to the information and adapt their travel behaviour. Alongside the development and implementation of ITS technology and information delivery systems, economic incentives, such as road pricing schemes, taxes and subsidies could be introduced to improve road network management. However, one of the key implementation challenges remains at the level of public acceptability. In addition, as most of the world’s population now lives in cities, factors affecting urban mobility should also be equally considered: e.g. car sharing schemes and the localised intensification of mass transport.

Science and technology challenges:

• Determining how air pollution through road transport can be reduced
• Determining how road-pricing schemes can be implemented efficiently
• Assessing the relative benefits of mass transport vs. individual transport, in terms of accessibility as well as ownership
• Assessing implications of autonomous systems, such as driverless cars
• Encouraging smart network management to reduce emissions and traffic congestion

28. Digital Privacy and the Individual

Personal privacy in the digital realm lacks a specific and practical definition, yet it impacts most socio-technical interactions. This gap between knowledge, research and policy needs to be bridged, and consequently a cross-disciplinary research agenda focusing on the balance of technical feasibility and legislative capabilities for digital personal privacy in an international context is required. Important issues include understanding of the impact that growing data repositories (i.e. big data) and potential step changes in computer power (e.g. quantum computing) might have on privacy and both personal and national security [134]; and the impact that human understanding of privacy can have on the behaviour of an individual and mechanisms for communicating privacy [135]. The end goal is establishing and communicating a unified understanding of and potential policy framework for data ownership to augment proposed legislative frameworks [136].

Science and technology challenges:

• Identifying mechanisms that enable effective utilisation of available data by private and public entities for commercial and/or national interests
• Understanding the impact growing data repositories and step changes in computer power might have on privacy and on personal and national security
• Assessing the benefits and risks of cloud computing
• Identifying regulatory, industrial and social discrepancies in definitions of digital privacy and their impact on privacy-related threats
• Investigating the potential for mitigating threats through behavioural change and improved public understanding of digital privacy

29. Changes in the Technology of Warfare

The means by which war is fought, and the means by which many wider security goals are achieved, are always changing. Throughout history advances in science and technology, or the innovative use of existing technology, have been major factors in those changes. Armed conflict is set within an international legal, moral and ethical framework [137], [138]. These ethical, moral, and legal frameworks also apply to the ways in which war is conducted. Recent technological advances have introduced new paradigms in warfare and national security matters that challenge the existing interpretation of the agreed international legal and ethical norms. Advances in autonomous vehicle use, such as “drone strikes”, have been widely debated with different interpretations [139], [140]. Cyber attacks challenge traditional interpretations of “combatants” and non-combatants” and even what defines war [141]–[143]. There are conflicting views and interpretations across the international community, and a common set of norms needs to be agreed to avoid all actions being judged after the event.

Science and technology challenges:

• Developing technical defences to disruption of the interconnectedness of automated and networked modern life
• Identifying and addressing the novel ethical and practical issues that affect the rules of international conflict, particularly in relation to Cyber/AI/Automation/Drones
• Identifying the factors that are changing the nature of deterrence and how this will affect the type and likelihood of attack
• Identifying and developing features that lead to improved resilience
• Determining how technology can contribute towards detection, attribution and response

30. Resource Frontiers and Geopolitics

Competition for resources has long been considered as a contributing factor in the cause of war or instability [144]. Access to resources can act as a source of funding and enrichment to the participants, providing personal wealth and thus acting as an incentive to continuing the conflict [145]. New global pressures, most notably climate change, population growth and the need to sustainably manage the world’s rapidly growing demand for energy and water have the potential to create a ‘perfect storm’ of global events [146]. Technology developments over recent decades have re-defined the resources that have strategic importance, and a new era of competition for “economically important raw materials which are subject to a higher risk of supply interruption” (as defined by the EU [147]) is underway. Many nations have set in place, or are developing, resource security strategies, including efficient use, waste minimisation, and resource substitution; the actual approach taken is nation specific. Some States have developed international policy towards ensuring access to strategic resources, such as China’s policy on engagement with Africa [148], [149]; others have focused on harnessing scientific developments to find alternative sources, such as bio-diesel, and fracking [150]. The UK Government has developed an Action Plan on resource security [151].

Science and technology challenges:

• Assessing likely future drivers of resource driven interests between countries and regions
• Assessing how Science and Technology could drive alternative technologies that replace current demands
• Determining how extraction technologies might change and the implications for resource availability
• Assess how the capability to exploit new forms of resources or new regional sources might change (e.g. exploitation of the Arctic region)
• Evaluating how can technology and geopolitics interact