@article{10.1371/journal.pone.0040988, doi = {10.1371/journal.pone.0040988}, author = {Rocha, Maria Gabrielle de Lima AND Faria, Fabio Lopes AND Gonçalves, Leonor AND Souza, Maria do Carmo M. AND Fernandes, Paula Ávila AND Fernandes, Ana Paula}, journal = {PLOS ONE}, publisher = {Public Library of Science}, title = {Prevalence of DNA-HPV in Male Sexual Partners of HPV-Infected Women and Concordance of Viral Types in Infected Couples}, year = {2012}, month = {07}, volume = {7}, url = {https://doi.org/10.1371/journal.pone.0040988}, pages = {1-7}, abstract = {Investigation of HPV infection in men remains important due to its association with genital warts and anorectal cancer, as well as to the role men play in HPV transmission to their female sexual partners. Asymptomatic men (n = 43), whose sexual partners had presented cervical HPV infection, were enrolled in this study. Among the 43 men, 23 had their female partner included and tested for HPV-DNA, totaling 23 couples. HPV-DNA was detected by PCR. Type specific PCR to detect HPV 16, 18, 31, 33, 45 and 6/11 was performed. At least one type of HPV was detected in 86.0% (37/43) of the male patients and more than one HPV type was identified in 39.5% (17/43) of the samples, including high and low risk HPV. HPV-16 proved to be the most prevalent viral type in both male and female samples. Concordance of at least one viral type was observed in 56.5% (13/23) of the couples. Among couples that have shown concordance of viral types, 84.6% (11/13) of the men had the same high risk viral type presented by the female sexual partner. These data suggest that HPV infected men is an important reservoir, contributing to a higher transmission to women and maintenance of infection, and consequently, a higher risk of developing cervical cancer. HPV vaccination in men will protect not only them but will also have implications for their sexual partners.}, number = {7}, }