#Contains_Novel_or_Only_Known(Annotated)_Junctions as_event_type gene_name chr strand exclusion_junctions inclusion_junctions exclusion_exons inclusion_exons intron-exon_junctions neighboring_constitutive_exons LAML-TCGA-AB-2803-Tumor LAML-TCGA-AB-2805-Tumor LAML-TCGA-AB-2806-Tumor LAML-TCGA-AB-2807-Tumor LAML-TCGA-AB-2808-Tumor LAML-TCGA-AB-2810-Tumor LAML-TCGA-AB-2811-Tumor LAML-TCGA-AB-2812-Tumor LAML-TCGA-AB-2813-Tumor LAML-TCGA-AB-2814-Tumor LAML-TCGA-AB-2815-Tumor LAML-TCGA-AB-2816-Tumor LAML-TCGA-AB-2817-Tumor LAML-TCGA-AB-2818-Tumor LAML-TCGA-AB-2819-Tumor LAML-TCGA-AB-2820-Tumor LAML-TCGA-AB-2821-Tumor LAML-TCGA-AB-2822-Tumor LAML-TCGA-AB-2823-Tumor LAML-TCGA-AB-2824-Tumor LAML-TCGA-AB-2825-Tumor LAML-TCGA-AB-2826-Tumor LAML-TCGA-AB-2828-Tumor LAML-TCGA-AB-2830-Tumor LAML-TCGA-AB-2832-Tumor LAML-TCGA-AB-2833-Tumor LAML-TCGA-AB-2834-Tumor LAML-TCGA-AB-2835-Tumor LAML-TCGA-AB-2836-Tumor LAML-TCGA-AB-2837-Tumor LAML-TCGA-AB-2838-Tumor LAML-TCGA-AB-2839-Tumor LAML-TCGA-AB-2840-Tumor LAML-TCGA-AB-2841-Tumor LAML-TCGA-AB-2842-Tumor LAML-TCGA-AB-2843-Tumor LAML-TCGA-AB-2844-Tumor LAML-TCGA-AB-2845-Tumor LAML-TCGA-AB-2846-Tumor LAML-TCGA-AB-2847-Tumor LAML-TCGA-AB-2848-Tumor LAML-TCGA-AB-2849-Tumor LAML-TCGA-AB-2851-Tumor LAML-TCGA-AB-2853-Tumor LAML-TCGA-AB-2854-Tumor LAML-TCGA-AB-2855-Tumor LAML-TCGA-AB-2856-Tumor LAML-TCGA-AB-2857-Tumor LAML-TCGA-AB-2858-Tumor LAML-TCGA-AB-2859-Tumor LAML-TCGA-AB-2860-Tumor LAML-TCGA-AB-2861-Tumor LAML-TCGA-AB-2862-Tumor LAML-TCGA-AB-2863-Tumor LAML-TCGA-AB-2865-Tumor LAML-TCGA-AB-2866-Tumor LAML-TCGA-AB-2867-Tumor LAML-TCGA-AB-2868-Tumor LAML-TCGA-AB-2869-Tumor LAML-TCGA-AB-2870-Tumor LAML-TCGA-AB-2871-Tumor LAML-TCGA-AB-2872-Tumor LAML-TCGA-AB-2873-Tumor LAML-TCGA-AB-2874-Tumor LAML-TCGA-AB-2875-Tumor LAML-TCGA-AB-2877-Tumor LAML-TCGA-AB-2879-Tumor LAML-TCGA-AB-2880-Tumor LAML-TCGA-AB-2881-Tumor LAML-TCGA-AB-2882-Tumor LAML-TCGA-AB-2884-Tumor LAML-TCGA-AB-2885-Tumor LAML-TCGA-AB-2886-Tumor LAML-TCGA-AB-2887-Tumor LAML-TCGA-AB-2888-Tumor LAML-TCGA-AB-2889-Tumor LAML-TCGA-AB-2890-Tumor LAML-TCGA-AB-2891-Tumor LAML-TCGA-AB-2895-Tumor LAML-TCGA-AB-2896-Tumor LAML-TCGA-AB-2897-Tumor LAML-TCGA-AB-2898-Tumor LAML-TCGA-AB-2899-Tumor LAML-TCGA-AB-2900-Tumor LAML-TCGA-AB-2901-Tumor LAML-TCGA-AB-2903-Tumor LAML-TCGA-AB-2904-Tumor LAML-TCGA-AB-2908-Tumor LAML-TCGA-AB-2909-Tumor LAML-TCGA-AB-2910-Tumor LAML-TCGA-AB-2911-Tumor LAML-TCGA-AB-2912-Tumor LAML-TCGA-AB-2913-Tumor LAML-TCGA-AB-2914-Tumor LAML-TCGA-AB-2915-Tumor LAML-TCGA-AB-2916-Tumor LAML-TCGA-AB-2917-Tumor LAML-TCGA-AB-2918-Tumor LAML-TCGA-AB-2919-Tumor LAML-TCGA-AB-2920-Tumor LAML-TCGA-AB-2921-Tumor LAML-TCGA-AB-2924-Tumor LAML-TCGA-AB-2925-Tumor LAML-TCGA-AB-2927-Tumor LAML-TCGA-AB-2928-Tumor LAML-TCGA-AB-2929-Tumor LAML-TCGA-AB-2930-Tumor LAML-TCGA-AB-2931-Tumor LAML-TCGA-AB-2932-Tumor LAML-TCGA-AB-2933-Tumor LAML-TCGA-AB-2934-Tumor LAML-TCGA-AB-2935-Tumor LAML-TCGA-AB-2936-Tumor LAML-TCGA-AB-2937-Tumor LAML-TCGA-AB-2938-Tumor LAML-TCGA-AB-2939-Tumor LAML-TCGA-AB-2940-Tumor LAML-TCGA-AB-2941-Tumor LAML-TCGA-AB-2942-Tumor LAML-TCGA-AB-2943-Tumor LAML-TCGA-AB-2944-Tumor LAML-TCGA-AB-2946-Tumor LAML-TCGA-AB-2948-Tumor LAML-TCGA-AB-2949-Tumor LAML-TCGA-AB-2950-Tumor LAML-TCGA-AB-2952-Tumor LAML-TCGA-AB-2954-Tumor LAML-TCGA-AB-2955-Tumor LAML-TCGA-AB-2956-Tumor LAML-TCGA-AB-2959-Tumor LAML-TCGA-AB-2963-Tumor LAML-TCGA-AB-2964-Tumor LAML-TCGA-AB-2965-Tumor LAML-TCGA-AB-2966-Tumor LAML-TCGA-AB-2967-Tumor LAML-TCGA-AB-2969-Tumor LAML-TCGA-AB-2970-Tumor LAML-TCGA-AB-2971-Tumor LAML-TCGA-AB-2972-Tumor LAML-TCGA-AB-2973-Tumor LAML-TCGA-AB-2975-Tumor LAML-TCGA-AB-2976-Tumor LAML-TCGA-AB-2978-Tumor LAML-TCGA-AB-2979-Tumor LAML-TCGA-AB-2980-Tumor LAML-TCGA-AB-2981-Tumor LAML-TCGA-AB-2982-Tumor LAML-TCGA-AB-2983-Tumor LAML-TCGA-AB-2984-Tumor LAML-TCGA-AB-2985-Tumor LAML-TCGA-AB-2986-Tumor LAML-TCGA-AB-2987-Tumor LAML-TCGA-AB-2988-Tumor LAML-TCGA-AB-2990-Tumor LAML-TCGA-AB-2991-Tumor LAML-TCGA-AB-2992-Tumor LAML-TCGA-AB-2993-Tumor LAML-TCGA-AB-2994-Tumor LAML-TCGA-AB-2995-Tumor LAML-TCGA-AB-2996-Tumor LAML-TCGA-AB-2998-Tumor LAML-TCGA-AB-2999-Tumor LAML-TCGA-AB-3000-Tumor LAML-TCGA-AB-3001-Tumor LAML-TCGA-AB-3002-Tumor LAML-TCGA-AB-3005-Tumor LAML-TCGA-AB-3006-Tumor LAML-TCGA-AB-3007-Tumor LAML-TCGA-AB-3008-Tumor LAML-TCGA-AB-3009-Tumor LAML-TCGA-AB-3011-Tumor LAML-TCGA-AB-3012-Tumor set1_med set2_med delta_val raw_pval corrected_pval K cassette ACAD8 chr11 + chr11:134126543-134128408 chr11:134126543-134126981;chr11:134127152-134128408 chr11:134126982-134127151 NA 100 57.89 100 100 NA 76.19 100 100 NA 100 NA 100 100 100 100 100 100 100 NA 100 NA 100 74.14 100 NA NA 75 69.23 77.27 100 100 NA 100 100 43.75 100 74.29 69.23 73.68 100 100 100 100 NA NA 79.17 100 66.67 78.38 100 61.9 70.83 100 100 100 NA 100 100 76.47 100 NA 73.91 100 75.86 100 78.79 100 100 58.33 100 100 75.68 76.47 100 72.73 75.86 100 80 82.35 100 100 100 80.77 100 NA 100 100 70 72.97 100 21.43 100 NA 61.11 NA NA 73.68 100 100 73.17 100 79.49 71.43 100 100 77.14 87.27 76.47 100 100 100 100 NA 100 100 74.29 100 NA 100 100 78.95 100 100 100 100 100 NA 76.47 NA 100 NA 100 100 100 100 100 NA 100 NA NA 55.56 NA 76.09 100 70.97 100 62.5 NA 100 NA 100 100 100 80 100 100 78.12 82.5 52.17 100 100 68.75 100 68.18 NA 80.56 80.95 82.35 100 100 100 100 55.25 -44.75 0.000008 0.000552 K cassette ACSF3 chr16 + chr16:89178655-89187208 chr16:89178655-89180746;chr16:89180896-89187208 chr16:89180747-89180895 100 100 100 100 100 100 82 100 100 100 100 100 100 100 100 100 100 89.13 84.62 100 82.76 100 100 100 100 100 100 100 100 100 100 100 100 100 100 70.37 100 100 100 100 78.12 69.7 100 100 76.74 100 100 89.58 100 88.37 100 100 100 100 100 100 100 100 100 100 100 77.27 100 100 100 100 100 100 100 91.23 100 100 100 100 82.05 100 100 100 86.84 100 100 89.8 100 100 100 100 100 94.62 100 100 100 72.22 100 100 100 100 100 100 100 100 100 87.5 100 100 100 100 100 100 100 100 100 87.04 90.57 100 100 100 100 81.48 100 86.59 86.54 100 100 91.36 100 100 100 73.33 100 65.62 100 100 100 100 100 100 100 58.82 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 81.08 73.33 78.05 100 100 100 81.82 91.23 100 100 100 100 100 100 100 82.28 -17.72 0.000956 0.02249 K cassette AKAP13 chr15 + chr15:86199019-86207793 chr15:86199019-86201767;chr15:86201822-86207793 chr15:86201768-86201821 NA 78.57 74.19 70 70.37 NA 70.59 100 63.06 68.89 75 100 70.18 76.92 55.17 46.67 69.39 100 60.42 42.31 72.82 100 79.79 77.27 66.67 100 77.08 71.05 82.72 80 75.93 61.54 100 70 69.39 84.38 81.25 58.97 67.8 100 77.59 0 69.81 42.86 75 44.07 70.59 74.19 61.9 70 58.54 100 NA 52.78 71.43 77.55 65.62 72 58.33 73.61 66.67 NA 82.73 100 53.12 50 100 64.86 80 75.68 64.29 61.4 76 67.92 83.05 65.91 84.31 56.25 72.41 100 50 60.61 67.92 66.67 67.12 30 48.39 84.85 69.77 74.07 71.88 100 58.82 66.67 66.67 68.79 75.76 65.62 64.29 72.22 74.19 71.93 69.44 83.87 71.43 67.27 64.52 63.83 79.69 75.44 75.32 53.85 69.57 NA 100 100 77.42 74.42 100 78.95 52.08 80.43 67.68 100 56.52 71.79 63.93 100 74.55 71.19 74.14 NA 80 100 78.05 65.52 100 77.94 NA 66.25 52.94 67.74 NA 62.96 100 78 100 84.38 NA 66.67 NA 75 46.67 NA 54.05 72.46 72.73 68.29 100 84.78 55.36 NA 57.14 76.47 57.14 100 50 58.33 56.67 76.92 41.18 68.18 71.12 92.39 21.27 0.002541 0.046671 N cassette ANAPC1 chr2 - chr2:112630986-112636386 chr2:112630986-112631189;chr2:112631242-112636386 chr2:112631190-112631241 NA 100 100 63.64 100 NA NA 100 86.49 77.59 100 NA 79.41 80 76.19 100 86.57 84.38 81.48 100 100 NA 100 100 100 100 100 100 83.33 83.87 100 80.82 100 100 100 100 100 80 86.79 70.83 100 100 100 81.25 100 83.33 100 89 100 83.05 83.78 74.19 100 100 88.89 100 100 88.71 100 82.69 82.72 76.19 100 90.77 91.57 100 84 84 83.33 77.19 85.37 85.19 88.89 82.35 82.14 100 100 85.11 84.62 89.47 100 100 77.42 100 92.31 100 100 100 83.52 76.32 58.82 70.91 100 100 77.78 100 84.62 93.06 88.89 79.71 100 87.5 100 100 87.95 71.64 100 88.31 100 100 76.47 100 85.71 100 73.08 79.49 82.5 80.65 100 78.48 73.91 86.79 100 87.88 100 75 100 100 82.81 100 90.91 100 100 100 100 100 100 100 100 100 83.33 100 100 87.93 100 100 100 100 100 100 NA 100 87.5 100 100 100 84.13 100 86.59 74.58 100 100 82.22 85.71 88.14 100 87.14 86.27 88.89 100 83.33 100 100 74.38 -25.62 0.001548 0.032373 N cassette ANAPC10 chr4 - chr4:145916756-146002811 chr4:145916756-145985723;chr4:145985845-146002811 chr4:145985724-145985844 100 100 100 100 100 NA 100 100 100 100 100 NA 100 100 100 100 100 82.76 100 100 100 100 100 100 100 100 100 100 100 100 76.67 100 100 100 100 100 100 86.36 100 68.09 100 100 80.65 100 100 100 100 88.64 100 100 100 78.57 100 100 100 100 100 100 100 100 80.77 100 100 100 100 100 100 NA 100 66.67 100 100 100 100 100 100 100 100 100 85 100 100 100 100 100 100 100 100 100 88.37 100 100 100 100 100 100 100 100 100 100 80 85.29 100 100 100 77.14 86.96 100 100 100 70 100 100 100 100 84.38 100 100 100 100 81.4 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 65.22 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 72.41 82.76 100 100 100 100 65.38 100 100 100 100 100 100 100 75.49 -24.51 0.000009 0.000653 N alternative_acceptor ANAPC5 chr12 - chr12:121766262-121768385;chr12:121766277-121768385 chr12:121766301-121768385 chr12:121766262-121766276;chr12:121766277-121766300 chr12:121766261-121766262;chr12:121766276-121766277 44.63 50.88 56.83 58.33 52.31 52.78 49.13 52.89 50.81 57.14 58.06 98.41 51.88 44.85 55.49 46.28 73.12 55.37 40.89 45.68 53.69 59.42 56.8 49.08 47.49 57.26 48.74 51.33 51.66 50 55.63 45 58.54 53.88 45.45 38.66 44.71 51.25 53.3 37.57 44.66 55.79 50.34 48.41 57.26 59.49 42.59 52.11 50 50 53.33 39.39 51.12 55.78 53.7 52.48 56.84 53.19 45.05 55.56 52.17 60.94 52.78 57.98 51.82 51.27 41.96 56.52 47.54 39.8 50 54.24 54.3 53.08 58.21 56.25 42.11 53.18 43.81 47.42 47.74 50 59.52 52.08 43.36 56.25 41.3 47.18 43.93 44.7 51.95 43.01 44.36 51.19 56.45 47.62 70 32.65 50.46 48.42 40.52 48.77 40.75 46.89 49.75 67.42 42.67 37.94 49.07 68.09 47.88 55.81 59.3 54.84 61.75 51.67 55.73 58.43 53.16 48.73 67.42 51.64 55.32 42.4 49.52 57.28 45.65 49.41 45.79 60.81 46.38 37.7 44.14 60.27 62.3 54.61 50.43 55.84 57.04 73.08 53.93 51.15 60 44.64 58.71 52.71 53.77 58.26 9.52 61.33 51.19 57.81 48.82 43.18 55.43 54.9 57.14 52.41 56.71 34.62 49.3 46.82 62.36 53.09 60.66 40.83 45.19 47.5 55.08 44.7 52.55 53.48 52.08 39.02 -13.05 0.0001 0.008111 N alternative_acceptor ANKHD1 chr5 + chr5:139815843-139818078;chr5:139815843-139818087 chr5:139815843-139818045 chr5:139818046-139818078;chr5:139818079-139818087 chr5:139818078-139818079;chr5:139818087-139818088 96 81.61 87.5 46.32 84.62 75.61 98.53 88.04 80.65 98.61 85.53 NA 80 86.67 80.28 78.46 89.62 84.29 79.8 81.48 81.82 58.62 89.47 91.67 83.33 98.18 98.33 82.35 78.82 86.52 81.97 98.28 97.56 96.88 88.66 65.08 80 80.77 98.9 49.57 97.78 86.27 90.36 80.56 97.67 80.72 80.49 68.75 90.77 86.59 82.26 70 97.37 69.23 77.42 84.31 78.26 85.19 98.57 81.73 91.11 82.61 80.95 80 86.14 77.08 75.31 93.18 89.36 35.11 87.84 75 85.71 86.54 75.32 86.42 81.82 79.73 85.07 98 90.62 92 77.65 88.89 82.35 80 95.65 96.77 82 80.68 66.67 54.9 98.11 98.55 79.35 98.28 73.58 86.42 88.89 92.86 98.21 77.98 82.26 98.44 81.93 41.43 82.11 75 98.11 86.67 86.96 97.3 69.12 95 69.88 78.72 87.84 81.95 71.15 87.88 38.36 84.04 60.19 88.64 85.53 96.77 80.36 89.47 81.25 98.44 84.09 83.33 88.75 98.15 77.61 67.92 87.5 82 98.28 62.5 96.43 98.15 97.92 98.15 98 90.32 96.97 89.25 93.75 98.25 97.96 98.75 86.25 65.12 98.57 84.21 79.22 83.56 73.29 50.46 89.19 97.67 85.11 79.45 56.47 84.78 81.18 85.9 87.36 83.15 83.08 98.59 85.15 52.68 -32.47 0.000084 0.007032 K cassette ANKRD36B chr2 - chr2:96525823-96542186 chr2:96525823-96533187;chr2:96533330-96542186 chr2:96533188-96533329 100 83.13 100 82.76 100 86.27 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.1 100 100 100 100 100 100 100 100 100 94.19 100 100 100 100 100 100 91.95 100 82.76 100 94.3 100 91.75 100 93.2 83.33 100 65.15 100 100 87.8 100 100 100 100 100 100 85.15 100 100 97.1 100 100 100 100 94.57 100 100 87.88 100 96.09 94.85 100 100 100 100 100 100 96.15 100 100 100 100 94.9 100 100 100 95.21 100 100 87.9 92.5 100 91.94 100 91.13 93.94 100 100 100 100 100 100 93.93 94.35 100 89.06 100 100 100 100 89.44 100 91.26 100 100 89.21 100 100 89.68 100 84.29 95.41 100 100 100 100 96.23 83.18 89.29 100 100 100 100 100 82.24 94.51 100 100 100 100 100 100 100 100 100 94.32 100 100 100 100 100 91.15 100 100 95.45 100 87.6 84.85 100 100 93.15 100 75.81 100 100 92.25 100 100 100 100 100 87.84 -12.16 0.000298 0.010858 N cassette ANKRD36B chr2 - chr2:98177324-98196924 chr2:98177324-98195368;chr2:98195507-98196924 chr2:98195369-98195506 100 100 90.16 70 77.14 100 NA 100 100 100 65.62 NA 100 100 100 62.96 64.15 82.14 83.33 NA 100 NA 100 100 100 100 100 100 57.89 100 81.25 87.8 100 NA 100 50 100 100 77.78 68.18 100 86.08 73.68 100 100 84.85 100 100 70 100 69.23 NA NA 70.45 100 100 100 100 78.57 100 82.76 78.12 100 100 86.57 100 63.41 100 100 75 100 67.35 74.19 76.27 100 100 76.32 84.21 84.62 82.5 100 86.49 100 100 87.93 60 62.22 100 87.5 54.55 100 70.45 100 85.71 100 100 72.09 61.54 75.44 76.47 100 100 NA 100 85.05 75 85.71 72.92 100 100 73.33 68.63 80.49 62.07 100 87.23 100 63.27 100 92.5 100 80 100 84.44 100 100 100 67.5 85.06 84.44 86.49 100 100 100 100 NA 62.16 100 67.21 100 60.87 73.47 100 64 100 NA 100 100 100 NA NA NA 77.42 100 75.76 79.41 64.56 100 69.05 62.07 100 100 77.42 100 75 84.21 75 80.77 74.19 68.63 92.11 100 100 68.18 -31.82 0.001142 0.02572 K cassette ANLN chr7 + chr7:36455494-36458852 chr7:36455494-36456688;chr7:36456800-36458852 chr7:36456689-36456799 NA 71.43 82.05 62.5 100 NA NA 100 80.56 NA 85.71 NA NA 100 100 NA 100 100 78.26 100 100 100 85.45 100 NA 100 85.71 87.8 100 100 100 100 100 100 82.73 66.67 82.76 80 72 73.91 100 100 NA 100 62.86 46.67 100 83.87 100 NA 82.02 78.95 NA 75.38 NA 100 100 100 100 72.41 NA 100 75 78.26 100 64.29 NA 72.22 100 NA 100 NA 100 100 100 80 NA 76.47 NA NA NA 100 75.56 100 80.56 NA 100 100 NA 75.36 100 79.59 100 100 100 NA 66.67 76 100 NA 100 100 100 100 NA NA 100 100 100 100 NA 100 100 NA 70.69 100 79.55 100 100 100 NA 62.86 67.44 100 76.09 NA 100 NA 84.09 100 81.48 100 100 NA 100 100 100 100 100 NA NA 100 NA 100 77.14 NA NA 100 NA 100 NA NA 100 82.35 100 82.46 100 72.22 78.12 72.34 74.24 NA 85.29 100 100 NA 100 66.67 86.49 100 100 100 100 73.91 -26.09 0.002002 0.039269 K cassette AP1AR chr4 + chr4:113182019-113186164 chr4:113182019-113184143;chr4:113184243-113186164 chr4:113184144-113184242 NA 100 100 86.84 100 NA NA 100 83.33 100 100 NA 100 100 100 NA 100 100 100 NA 100 100 100 100 100 100 100 81.48 100 100 100 100 NA 100 100 100 100 100 82.14 77.27 NA 100 100 100 100 100 100 86.49 100 100 100 72.41 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 80.77 100 100 100 83.87 100 100 100 90.2 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 78.38 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 NA 100 100 100 100 100 NA NA NA 100 100 100 100 100 100 100 100 76.32 100 100 100 80.77 65.22 100 100 100 100 100 100 100 100 88.63 -11.37 0.000165 0.00708 N alternative_acceptor AP1G2 chr14 - chr14:24032512-24032588;chr14:24031788-24032588;chr14:24031803-24032588 chr14:24032492-24032588 chr14:24031788-24031802;chr14:24031803-24032491;chr14:24032492-24032511 chr14:24031787-24031788;chr14:24031802-24031803;chr14:24032491-24032492 50 68.67 48.28 56.44 61.48 44.06 34.93 53.85 52.14 54.34 61.08 28.03 40 53.11 23.91 44.68 57.31 55.34 43.82 15 48.7 63.89 55.79 44.88 22.4 65 58.39 35.56 52.1 55.74 47.68 41.73 45.61 52.3 58.26 67.57 46.34 41.15 45.4 65.31 47.74 56.96 41.25 52.13 32.67 45.77 33.83 42.22 50.88 47.14 49.66 66.24 40.96 55.48 49.24 56.09 51.16 54.23 53.85 44.44 43.87 55.56 46.95 44.59 44.04 47.46 50.39 42.29 48.04 51.35 48.18 49.07 54.12 48.61 56.7 46.12 43.6 47.01 43.98 49.09 41.67 58.14 44.63 41.32 49.7 53.66 73.83 46.67 46.75 47.06 48.07 82.5 55.81 27.03 38 53.75 76.47 42.68 45.71 31.4 49.13 53.7 39.92 44.2 47.41 31.98 51.33 45 46.44 60 44.16 43.53 59.51 60.64 39.19 45.77 41.43 57.86 61.54 43.78 15.49 44.05 59.22 48.33 47.67 35.63 41.48 55.1 40.1 69.61 50 21.31 63.04 61.21 26.37 48.57 57.14 60.71 51.39 59.86 66.85 54.74 61.7 34.89 53.06 48.26 52.78 25.87 25.86 50.39 19.18 45.07 48.33 53.18 41.61 57.06 50 47.43 45.05 73.2 45.28 48.32 48.51 50.89 48.62 44.26 49.04 42.69 37.56 42.02 40.54 39.82 48.07 66.91 18.84 0.000377 0.023757 K cassette AP2B1 chr17 + chr17:33984811-33998772 chr17:33984811-33997875;chr17:33997918-33998772 chr17:33997876-33997917 35 50.94 33.33 48.21 32.5 58.33 52.17 29.23 45.07 45.83 30.61 21.51 41.67 35.63 25.64 36.79 33.91 39.64 39.91 45.53 40.82 66.67 24.27 46.88 41.9 54.17 32.88 33.97 33.55 33.06 41.51 37.76 100 47.22 46.22 52.5 34.07 30.08 31.97 55.56 66.67 26.56 32.52 23.31 37.18 19.81 43.44 43.39 34.58 38.64 34.02 56.92 49.06 42.55 46.48 54.65 43.33 51.38 36.36 35.77 38.57 37.5 40.21 34.04 41.75 33.33 30.65 41.83 37.09 42.11 36.79 26.46 30.07 42.5 37.93 35.12 46.85 51.97 38.64 33.12 43.84 48.15 50 39.58 43.24 35.56 34.38 48.75 45.36 47.1 21.43 50 47.76 46.55 39.11 24.64 33.68 13.73 36 48.98 39.92 37.11 40.94 38.57 45.87 45.73 43.26 33.13 31.07 45.83 33.57 37.5 49.44 35.19 48.96 45.74 30.72 24.15 25 57.89 49.36 40.67 40 32 34.93 41.88 25 36.36 35.58 55.36 31.33 38.84 34.51 38.55 41.57 33.75 46.25 36.84 37.36 39.62 29.67 38.37 36.52 40 26.35 32.73 37.5 32 NA 30.49 0 42.31 37.23 43.75 45.98 35.37 34.75 40.74 39.55 50.76 43.95 35.29 42.11 40.58 55.14 55.56 33.7 47.96 39.21 39.13 43.75 43.7 38.74 51.63 12.89 0.001142 0.02572 N alternative_acceptor API5 chr11 + chr11:43357545-43363977;chr11:43357545-43363982 chr11:43357545-43360790 chr11:43360791-43363977;chr11:43363978-43363982 chr11:43363977-43363978;chr11:43363982-43363983 61.29 21.62 22.48 39.24 26.73 NA 11.54 34.62 25 23.96 26.88 28.33 21.15 27.47 19.79 21.9 29.25 23.85 30.68 13.33 13.27 34.33 20.34 22.86 15.79 30.65 26.6 14.71 29.23 23.53 18.69 28.05 34.62 38.24 20.93 35.29 29.47 33.72 22.34 44.59 30.23 34.88 25.35 21.55 29.69 14.56 11.11 19.47 22.89 33.33 21.85 36.73 37.5 23.24 28.07 27.42 28.99 23.91 19.74 17.35 23.38 48.94 17.39 23.33 20.21 18.18 20.41 20.93 23.75 44 22.99 17.11 29.21 18.39 27.71 18.45 30.43 16.46 20.97 26.83 42.5 21.88 20.48 18 19.82 35.37 32.26 20.9 28.77 19.7 38.89 48.84 31.25 30.59 20 33.75 42.7 22.45 28.36 21.28 20.51 18.75 15.25 34 21.51 18.48 25.84 19.78 20 39.39 29.85 22.62 31.87 23.81 20.88 20.51 23.33 28.09 38.46 21.08 21.25 26.25 31.63 38.6 31.25 12 24.53 37.5 22.55 45.78 21.77 28.05 28.41 22.83 29.31 18.46 30.3 56.41 25.64 40.48 27.08 26.67 32.84 18.42 37.78 19.15 45.71 40.96 31.25 20.83 18.75 21.43 25 35.8 28.57 21.69 37.14 34.43 30.39 44.33 21.05 50.91 20.65 25 42.55 26.67 24.24 33.85 19.39 23.81 40 23.73 24.38 44.16 19.78 0.000371 0.023455 K alternative_acceptor ARHGAP11A chr15 + chr15:32921964-32925263 chr15:32921964-32925179 chr15:32925180-32925263 chr15:32925263-32925264 NA 100 100 100 100 NA 100 100 100 100 100 NA 100 100 100 NA 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 75 100 100 100 100 100 100 100 100 100 100 100 84.91 100 89.36 100 100 100 100 100 78.57 100 100 100 100 100 100 100 100 100 80 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 83.82 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 NA NA 100 100 100 100 70.59 NA 100 NA 100 100 NA 100 100 NA 100 100 NA 82.76 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 84.36 -15.64 0 0 K cassette ARHGAP27 chr17 - chr17:43481463-43481810 chr17:43481463-43481634;chr17:43481701-43481810 chr17:43481635-43481700 NA 51 41.38 40.2 54.05 41.67 38.4 33.33 40.71 100 36.19 40 54.44 44.57 54.55 45.07 34.31 53.7 51.92 34.15 59.68 52.83 57.5 55.56 57.81 36.79 46.15 30.61 61.36 58.43 56.79 40.43 47.62 68 47.37 28.42 39.44 38.04 40 29.41 41.18 32 43.52 53.57 39.13 25.23 46.77 34.92 42.86 48.48 45.16 26.19 33.33 29.17 43.69 64.58 27.27 49.02 74.29 42.94 39.68 37.5 37.31 35.85 34.69 36.67 59.26 39.71 50.62 40.58 36.67 31.76 45 53.85 47.97 54.29 40.52 29.41 60.87 56 28 54 23.02 46.67 57.14 NA 40.91 57.78 46.34 50.63 39.74 18.75 48.72 37.84 37.76 32.29 33.33 52.22 51.92 50 51.69 50.52 50 43.36 55.41 42.15 54.55 58.33 42.79 35.53 56.25 34.85 43.62 51.85 47.37 66.35 37.8 36.67 45.45 58.33 43.59 37.25 48.05 37.14 56.52 44 49.54 27.27 48.75 39.53 50 NA 36.67 100 35.85 52 43.55 51.61 50 54.67 36.84 41.67 100 52.73 47.62 46.2 35 54.76 8 42.45 0 42.11 55.26 48.57 31.91 51.09 37.14 39.71 52.94 31.91 45.9 9.09 36.59 37.93 35 47.06 52.38 36.67 44.59 56.67 37.21 34.62 44.58 28.91 -15.66 0.001037 0.02406 K cassette ARID1B chr6 + chr6:157256711-157405795 chr6:157256711-157357968;chr6:157358011-157405795 chr6:157357969-157358010 38.71 42.61 35.77 37.87 34.38 72.97 85.71 38.83 46.94 40.24 57.14 0 41.46 56 25.71 46.23 50.3 42.31 37.04 36.51 69.64 40.48 67.39 51.69 66.1 53.57 54.55 70.18 45.98 54.05 50.62 33.75 20 40 63.49 61.04 41.75 45.54 56.94 62.2 48.98 38.71 50.7 50.42 41.67 42.2 33.33 48.31 40.86 39.87 43.04 68.75 33.33 53.33 36.84 50 58.23 57.83 37.93 39.13 38.1 42.68 65.22 38.93 42.54 50 36.24 33.67 39.08 54.37 42.11 37.6 38.95 40.6 57.69 47.56 50.72 53.01 42.76 40.3 30 32.08 35.94 48.53 49.52 33.33 26.25 45.35 48.84 58.21 44.12 54.93 33.33 34.92 50 61.4 37.7 48.84 36.36 53.38 43.75 61.62 52 49.4 35.82 57.97 45.7 41.23 59.79 53.03 55.74 27.85 27.45 39.84 53.09 45.03 46.25 28.49 34.78 54.12 51.09 47.15 53.27 45.99 37 42.03 49.21 45.61 60.94 28.76 54.21 43.58 37.08 33.33 51.61 45.65 44.32 54.39 36.76 100 40.54 40.74 28.7 38.97 29.63 50.88 29.55 38.82 29.41 40 15.62 60.53 46.79 50.62 32.86 35.29 49.58 46.94 28.34 63.36 45.45 32.76 38.17 37.65 36.36 48.39 41.33 34.83 49.7 27.18 42.4 38.78 42.61 61.62 19.01 0.000538 0.014969 K cassette ARID1B chr6 + chr6:157495252-157502102 chr6:157495252-157495980;chr6:157496140-157502102 chr6:157495981-157496139 100 61 54.09 51.94 46.15 43.64 28.21 43.92 34.72 50 49.28 100 42.86 44.44 58.82 61.74 40.48 54.73 50.44 61.54 50.91 51.85 58.75 40 45.56 45.07 58.06 39.08 49.15 50.65 43.14 50 46.67 32.47 41.56 66.67 53.28 43.8 46.79 60.87 31.75 60.99 37.93 47.89 35.29 75.78 40.68 57.6 63.21 54.7 45.97 52.94 46.25 43.87 52.76 45.92 50.77 47.17 46.81 52.8 50.25 47.44 49.06 50.75 51.7 56.12 60 47.12 50.55 64.52 33.33 36.47 78.12 44.67 39.06 54.65 36.27 42.48 47.83 38.31 37.04 50.74 48.77 44.87 66.09 53.98 41.98 32.73 43.28 43.02 56.45 85.94 52.76 64.29 41.55 54.29 62.03 31.25 49.3 50.6 45.58 42.14 63.08 47.79 44.79 49.72 45.22 43.36 48.03 50.72 59.74 41.46 47.76 71.96 44.17 39.51 56.72 54.03 27.63 59.18 48.77 43.41 49.28 41.18 60.54 51.02 54.05 63.04 55.84 64.46 49.72 47.78 56.79 61.95 56.36 54.55 52.53 64.91 60.31 40 54.12 53.85 58.73 55.41 52.38 41.67 40.35 53.85 45.21 60.98 44.68 50 45.45 56.67 47.79 50.63 37.97 30.51 65.47 70.25 42.53 38.55 53.21 49.75 41.5 54.72 43.85 41.94 51.13 44.19 44 45.95 49.15 65.59 16.45 0.000672 0.017353 N alternative_acceptor ARMC8 chr3 + chr3:138003369-138007889 chr3:138003369-138006473 chr3:138006474-138007889 chr3:138007889-138007890 19.35 18.52 19.75 18.87 17.7 38.89 29.31 22.22 17.39 9.3 16.07 NA 15 13.33 15.52 13.89 18.18 26.42 7.84 7.32 8.33 19.44 11.76 17.5 10.64 17.24 17.07 16.67 9.68 11.11 9.88 24.39 11.76 14.04 11.54 25.93 11.76 9.56 12.31 31.75 24.39 28.57 8.33 16 26.47 5.48 8.06 12.21 7.14 7.89 6.56 33.33 6.52 20 14 14.49 26.67 16 10.26 11.29 13.33 21.74 14.75 11.32 11.27 34.88 16.67 11.39 17.65 32.58 12.94 12.5 10.53 13.43 13.04 10.53 28.12 11.11 12.96 7.69 20.59 22.41 14.29 19.15 12.24 14.93 20 13.33 17.54 8.33 19.61 36.36 17.02 15.38 11.39 12.31 27.94 13.46 19.75 23.08 8.65 18.18 9.46 35.29 34.88 16.28 16.67 8.7 17.24 34.15 10.45 17.74 17.5 26.67 10.14 18.75 10 14.44 18.52 14.43 15.69 15.08 20.93 19.74 15.52 15.79 15.62 25.64 9.41 28 17.91 20.37 16.13 17.19 31.25 11.76 14.49 22.22 26.09 13.04 45.16 20 15.87 8.65 14.52 10.99 16.22 19.15 NA 16.67 11.76 16.13 10 28.3 20.83 15.52 19.23 26.92 9.64 31.37 11.11 16.67 7.69 12.5 17.86 10 9.23 16.67 11.7 13.33 15.69 15 15.52 32.16 16.64 0.000166 0.012505 K cassette ARRB1 chr11 - chr11:74980004-74983938 chr11:74980004-74982744;chr11:74982769-74983938 chr11:74982745-74982768 20.83 40.62 13.17 42.86 23.58 26.58 12.33 16.39 19.07 29.8 19.12 24.79 15.91 14.15 28.32 31.28 18.42 23.33 20.29 0 18.58 32.11 14.62 26.81 39.39 29.17 26.56 27.45 27.24 32.07 17.85 25.41 11.43 16.53 27 9.89 16.81 25 16.56 9.09 12.59 18.67 20.33 19.35 33.33 28.68 25.11 20.21 20.21 23.5 16.54 13.64 22.48 28.19 40.43 28.41 23.02 33.62 22.81 19.82 22.64 11.7 24.03 15.44 18.65 18.58 19.39 25 18.18 8.37 11.59 16.07 26.5 15.24 15.28 17.42 20 23.38 14.05 16.19 30.85 23.88 26.92 21.21 20.53 34.62 16.97 29.37 17.93 30.13 14.62 5.08 23.23 19.51 25.29 27.13 45.78 11.94 18.5 25.53 29.21 22.64 21.4 24.3 15.81 23.95 35.67 19.49 29.13 45.68 26.56 15.15 44.97 14.17 29.63 18.37 27.15 12.27 28.95 33.14 24.85 23.77 36.69 20.27 29.27 19.78 22.88 27.71 23.73 39.24 35.29 33.68 32.63 19.79 36.51 27.43 21.5 19.57 31.37 18.09 31.88 22.79 36.67 21.74 22.73 26.67 28.95 22.43 17.54 27.83 16.44 37.65 21.35 29.82 14.14 17.32 19.57 11.65 18.04 14.86 15.38 21.92 26.47 21.53 50 24.27 18.54 28.7 25.42 17.42 11.85 16.2 22.81 9.49 -13.32 0.000103 0.004929 K cassette ARRB2 chr17 + chr17:4614040-4619267 chr17:4614040-4618307;chr17:4618339-4619267 chr17:4618308-4618338 100 66.24 66.67 87.21 81.93 77.78 70.91 83.33 51.37 71.7 72.15 62.37 69.51 64.03 80 88.89 87.3 87.26 63.19 59.09 42.03 57.47 60.16 60.14 63.41 59.23 55.45 56.83 62.27 60.95 62.5 79.55 64.29 71.37 51.92 46.07 66.67 67.52 66.88 47.37 58.67 100 48.87 75 58.69 65.62 47.71 70.83 72.73 63.33 53.42 56.41 66.67 82.76 69.64 66.06 76.77 69.57 70.49 61.19 83.33 100 55.99 76.92 75.27 100 100 67.21 65.54 55.67 57.71 72.07 71.25 78.81 59.64 64.43 70.21 78.48 71.79 72.88 76.09 75.76 43.75 72.55 75 100 73.33 63.51 77.66 62.35 55.49 48.51 75.76 59.26 60.33 45.98 72.22 51.82 74.17 66.43 63.82 62.28 56.86 70.55 88.04 77.14 73.55 78.7 60.42 60.32 64.77 58.12 76.6 74.81 34.29 71.51 62.22 76.92 67.93 62.69 74.16 58.03 55.47 62.89 56.82 58.46 55.42 83.67 53.11 100 72.22 62.86 61.9 81.48 56.1 61.83 70.89 54.17 78.57 68.98 60 65.91 66.99 71.53 60.61 56.63 71.11 75.56 77.91 60.4 76.25 60.83 68.97 81.11 69.84 60.54 73.68 56.76 70.77 40 60.58 100 59.06 64.81 74.44 68.75 59.32 62.9 71.43 81.25 85.71 60 66.99 47.94 -19.05 0.000174 0.007394 K cassette ASPH chr8 - chr8:62557192-62563608 chr8:62557192-62559308;chr8:62559438-62563608 chr8:62559309-62559437 100 56.31 92.44 90.72 72.31 68.42 100 100 80 93.48 82.42 100 100 73.08 86.84 62.5 84.13 92.37 69.71 100 77.46 80.6 81.82 89.04 100 71.83 50 73.4 64.81 78.26 86.4 82.58 80 73.53 89.52 65.85 76.19 83.17 81.82 55.81 78.85 NA 95.24 81.4 88.52 52.5 72.73 80.22 100 81.93 80.77 70.75 88.89 83.38 75.86 93.02 94.64 80.23 85.37 73.64 91.57 73.58 76.87 76.79 84.62 88.41 79.73 72.06 81.97 73.2 90.7 78.41 73.49 87.5 68.04 77.88 NA 67.53 86.89 79.34 86.21 100 NA 83.72 85.04 71.43 100 91.94 86.05 75.38 62.75 69.11 88.98 87.13 66.2 72.55 66.67 59.86 88.17 86.15 73.26 82.31 100 83.33 87.41 50 81.11 85.86 71.88 86.36 78.05 67.47 86.67 100 78.38 86.11 65.22 56.94 93.88 86.27 62.12 79.17 83.33 91.18 83.67 76.92 85.11 82.46 77.05 100 85.26 100 77.61 87.5 88.24 75.56 70.31 89.55 100 100 71.7 77.42 100 65.96 80.81 80 80.77 70 100 68.18 100 70.83 83.64 82.61 88.28 84.34 86.67 64.13 82.46 61.47 77.54 100 67.9 78.99 78.99 77.14 82.42 85.55 80 NA 86.79 85.19 82.31 67.48 -14.83 0.000897 0.02168 K cassette ATF2 chr2 - chr2:175945494-175957788 chr2:175945494-175957270;chr2:175957345-175957788 chr2:175957271-175957344 NA 6.25 7.69 33.33 15.62 NA 54.29 29.63 13.33 4.55 12.5 NA 20 11.36 22.22 23.08 28.07 18.75 17.74 0 2.94 15 2.3 16.22 27.78 3.57 5.26 27.03 2.56 9.09 10.64 12.77 8.33 18.75 8.7 28 14.29 20 17.65 41.38 35 25 13.51 12 NA 16.67 12 37.5 4.88 3.17 4.88 57.14 0 17.65 5.45 4.35 12.5 14.63 2.99 7.27 18 48.15 35.9 20 18.64 25 2.9 33.33 27.27 23.26 11.76 29.79 0 14.89 11.43 8.33 27.27 13.64 2.22 26.67 40.74 11.36 2.33 17.65 11.76 11.11 12.9 25 30 13.73 15.38 62.86 8.11 11.11 12.7 12.82 14.81 13.64 10 37.04 12.5 16.33 10.53 23.08 38.98 21.67 8.33 12.5 18.18 NA 9.3 26.47 13.51 15 2.78 11.29 7.27 26.67 12.9 9.09 27.12 35.71 12.96 34.62 15.28 8 2.7 45 15.79 9.3 5.66 17.02 5 15.15 10.26 0 2.04 20.83 18.75 14.29 23.08 14.29 0 20.59 11.11 22.5 45 5.88 21.74 0 0 NA 30.23 5 27.69 21.82 29.41 41.38 15.38 28 14 12.5 2 15.69 26.09 7.41 4.35 19.64 27.27 8.33 25.93 18.75 14 34.69 20.69 0.00059 0.015834 N alternative_acceptor ATR chr3 - chr3:142169394-142171969;chr3:142168445-142171969 chr3:142169445-142171969 chr3:142168445-142169393;chr3:142169394-142169444 chr3:142168444-142168445;chr3:142169393-142169394 11.36 11.63 13.79 13.04 12.5 23.08 35.56 16.67 14.29 10.42 9.76 NA 15.15 25.64 13.04 13.89 20 12.82 6.25 5.71 8.33 7.14 16.13 10 17.74 NA 6.67 21.74 14.29 11.9 17.95 9.3 12.9 17.14 9.68 30 16.22 15.07 15.38 37.5 17.95 20.59 7.69 24.44 32.61 8 13.64 19.57 5.88 11.36 14.04 33.33 6.38 14.93 10.34 8.82 NA 13.89 23.21 15.79 23.81 11.76 18.18 10.26 19.57 20 17.39 13.21 17.86 32.14 10.71 8.33 18.03 15.91 19.44 11.9 16.67 13.51 19.64 11.11 22.86 36.36 23.53 34.78 10.53 10 10.53 24.32 20 13.56 NA NA 8.82 20 14.29 10 17.39 9.26 27.03 25 12.71 19.51 15.52 21.15 16.98 23.91 26.23 9.86 18.75 13.04 8.06 12.31 23.91 NA 6.45 21.95 5.36 3.7 19.05 34.29 12.5 19.23 18.87 19.61 6.78 19.35 11.11 24.53 5.13 12.5 25.58 16.67 11.11 21.43 11.11 NA 8 38.89 13.79 NA 13.64 13.04 15.15 21.95 15.79 12.28 16.22 12.5 5 10.34 7.69 13.33 15.15 17.72 11.11 12.5 20.37 10.71 25 53.33 7.14 10.17 5.56 10.71 5.26 16.22 7.69 10.26 7.27 12.24 12.96 18.18 13.79 33.33 19.54 0.000296 0.019997 N cassette ATRX chrX - chrX:76944418-76952064;chrX:76944421-76952064 chrX:76944418-76949312,chrX:76944421-76949312;chrX:76949427-76952064 chrX:76949313-76949426 NA 67.86 68.52 81.08 76.6 NA NA 66.23 56.67 80.28 58.46 NA 61.67 64.15 82.05 61.4 69.44 72.28 66.18 100 50 100 82.81 81.67 60.87 100 100 55.26 48.89 65.12 68.6 66.67 100 NA 40.24 55.17 64.15 63.04 55.77 54.79 100 57.02 55.56 73.97 100 43.55 NA 61.4 55.74 61.04 68.83 53.33 70 65.31 70.97 47.06 57.81 70.51 62.22 57.61 71.25 59.38 57.78 65.12 56.58 81.48 62.12 55.71 61.19 50.6 72.73 62.16 65.31 72.83 63.1 59.42 67.06 67.31 71.83 62.16 59.38 65.31 62.86 55.17 64.29 100 100 100 57.65 39.29 72.22 55.56 65.62 69.51 56.58 44.29 72.41 60 62.96 100 57.14 66.67 64 60 60.91 57.45 56.52 64.15 46.43 81.82 48.28 64.58 77.55 100 68.69 72.73 60.56 55.71 100 73.17 64.91 64.37 56.25 63.4 64.71 72.73 53.7 75 50 62.5 51.47 100 100 70.43 76 NA 53.73 66.67 66.67 66.67 100 100 65.45 69.23 100 69.23 100 52.24 NA 100 NA 75 79.71 58.14 100 63.64 71.05 57.89 68.22 52.22 66 100 62.35 82 61.76 60 71.26 66.67 72 72.13 67.5 75 65.81 54.06 -11.75 0.000576 0.01556 K cassette BAZ1A chr14 - chr14:35255208-35261980 chr14:35255208-35255331;chr14:35255428-35261980 chr14:35255332-35255427 73.73 100 74.17 100 86.39 86.21 72.66 76.6 71.28 78.12 73.17 100 79.17 63.5 85.52 80 45.68 72.41 88.17 69.86 74.29 91.21 72.58 80 59.26 100 80.57 77.4 70.64 68.87 70.14 72.07 100 100 56.52 86 78.91 79.69 77.05 100 84.13 72.6 64.37 60.91 83.84 67.82 77.54 85.33 76.35 73.24 76.26 100 83.87 74.79 85.26 86.27 79.07 54.74 77.22 73.28 77.97 85.65 76.97 73.68 86.82 78.49 82.43 87.21 74.49 100 78.63 83.82 80.6 74.14 75.56 71.93 84.75 80.65 71.43 88.89 82.69 61.62 78.08 76.92 84.72 83.87 78.95 76.47 77.88 84.38 100 100 73.68 80 66.67 78.79 100 78.29 63.04 100 83.9 65.64 65.47 71.7 91.25 81.18 79.41 87.5 67.3 93.24 68.07 89.53 82.89 100 57.72 74.19 72 84.62 100 66.67 80.82 76.72 78.57 78.95 80.81 84.62 73.68 78 76.47 100 67.55 85.44 74.39 69.23 60.66 71.25 83.33 100 83.53 68.63 77.78 67.09 100 88.71 81.25 82.39 70.45 84.38 NA 77.19 75.56 78.4 80.26 89.01 78.33 75.28 82.35 81.08 86.54 92.86 74 80 81.25 70.31 100 79.89 78.12 79.37 78.12 82.14 70 73.61 78.44 100 21.56 0.000419 0.013484 K alternative_acceptor BCOR chrX - chrX:39923104-39923588 chrX:39923206-39923588 chrX:39923104-39923205 chrX:39923103-39923104 27.78 14.29 42.5 38.71 31.43 NA 76.56 58.33 42.86 23.08 29.17 NA 36 27.27 17.86 26.67 37.21 52.5 30 40.62 33.33 NA 20 31.91 37.14 NA 36.36 46 37.93 33.33 28.57 36.84 18.18 20 29.33 4.17 31.82 40 54.17 27.4 58.33 NA 31.11 35.9 16.67 31.25 30.56 63.33 25.71 37.25 21.82 26.53 33.33 41.3 30 35.9 100 32.35 26.09 27.27 45.71 48.72 40 39.02 31.25 48.39 34 41.18 26.92 20 45.71 52.94 36.84 26.09 32.43 26.83 46.81 36.17 26.67 50 66.67 39.29 28.12 48 41.86 21.95 39.47 45.71 48.89 37.96 39.29 11.54 46.88 31.58 33.33 36.67 45.71 32.5 34.69 28.33 23.19 52.08 35.19 50 47.37 26.32 30.91 39.13 47.37 34.62 18.18 44.12 33.33 28.57 27.78 28 13.56 42.11 31.43 28.57 48.15 58.33 32.2 58.06 40 33.33 42.31 14.81 29.55 100 29.17 35 35.14 29.63 24.24 24 41.54 62.5 43.55 20.59 40.62 39.29 25.93 37.04 33.33 39.29 26.67 26.09 23.08 31.03 100 NA 44.83 55.26 45.83 43.33 28.21 54.84 26.92 20 34.29 41.18 38.18 36 45.71 19.64 35.9 35.29 30.36 31.43 53.57 45.71 35.9 20 -15.9 0.00046 0.026105 K alternative_last_exon BPTF chr17 + chr17:65972075-65978367 chr17:65972075-65977551 chr17:65978368-65980493 chr17:65977552-65977876 33.33 41.41 45.19 35.9 40.3 25 18.37 41.98 50.75 46.71 38.71 56.72 49.44 39.13 36.89 45.76 33.33 39.39 40.62 46 51.52 35.29 55.74 42.42 41.86 40.96 35.65 44.59 38.89 47.06 45.45 45.22 47.78 46.27 42.38 49.28 42.97 35.38 43.33 51.7 48.39 41.28 42.47 40.79 45.38 45.45 36.49 47.17 36.8 46.02 43.94 56.79 40.26 32.46 37.1 45 44 36.17 43.3 38.1 50.57 44.19 43.4 35.9 45.24 32.11 33.33 41.46 34.57 47.59 41.57 40.91 42.74 32.11 41.11 41.46 45.26 54.13 38.1 36.76 45.83 37.33 44.16 36.36 38.75 27.63 39.33 35.16 33.71 41.77 39.22 54.47 46.96 41.05 44.83 50.75 36.4 35.48 36.5 37.31 31.65 49.32 39.58 38.61 36.76 44.06 40.26 33.81 37.08 47.58 42.22 40.35 34.65 47.92 37.23 30.36 44.17 32.39 49.07 42.05 48.18 44.23 45.83 35.19 42.4 43.64 41.38 35.29 36.67 37.29 43.07 38.83 48.39 35.84 49.37 44.87 43.95 47.52 43.36 52.63 44.29 46.85 39.06 40.24 44.92 37.31 42.11 48.59 29.33 34.41 37.04 38.96 36.99 30.91 38.71 43.55 43.33 41.27 37.11 54.64 33.78 33.13 38.38 41.76 45.21 44.93 38.95 36.47 41.75 40.82 35.29 40.82 41.05 53.09 12.04 0.000123 0.021773 N cassette BPTF chr17 + chr17:65871137-65887959;chr17:65871861-65887959 chr17:65871137-65882243,chr17:65871861-65882243;chr17:65882433-65887959 chr17:65882244-65882432 60 83.12 56.52 76.56 71.43 70.59 NA 62.2 57.14 67.74 81.13 100 70.59 82.93 100 77.78 59.76 61.76 73 40 72.22 100 57.81 67.74 75 100 100 65.85 65.67 69.84 64.52 64.77 100 56 65.75 47.06 76.12 69.23 74.14 53.4 55.81 73.29 76.92 82.61 59.52 79.31 48 75.82 73.68 75 75 63.64 57.45 77.53 64.79 72.34 60.47 61.9 65.91 69.23 61.39 81.13 63.27 69.41 68.09 78 66.67 57.14 62.03 62.22 66.04 64.89 82.57 73.83 58.93 71.15 63.16 63.86 68.92 72.86 78.38 81.97 79.41 70 73.91 75.4 66.67 61.54 64.6 84 72.92 49.49 79.78 74.12 58.67 69.64 77.42 54.67 72.62 76.79 71.67 66.18 66.67 84.78 75.65 75 73.5 66.13 100 70.09 87.93 62.22 80.36 100 80.9 55.06 72.29 49.28 58.97 70.73 78.85 59.57 76.67 68.29 83.33 43.9 73.33 63.51 72.34 82.98 62.5 75 77.03 84.04 78.05 100 72.5 61.54 57.78 55.17 72.41 68.75 100 71.79 100 74.42 80.65 79.52 100 58.54 29.73 72.5 55.84 79.59 55.74 74.67 78.48 58.33 76.11 40.91 57.33 59.76 65.15 52.5 70.69 65.52 56.57 77.03 65.71 68.75 62.32 66 70.64 51.45 -19.2 0.000978 0.022868 K coord_cassette BPTF chr17 + chr17:65871137-65887959 chr17:65871137-65871671;chr17:65871861-65882243;chr17:65882433-65887959 chr17:65871672-65871860;chr17:65882244-65882432 42.86 75.93 36.17 70.59 56.86 NA NA 38 51.61 77.05 72.22 100 76.6 82.5 100 54.84 61.64 55.17 64.91 37.5 74.36 100 41.38 56.25 68 100 100 51.72 65.62 76.74 67.31 53.73 100 42.11 73.02 6.25 63.64 58.21 59.46 36.92 34.48 45.57 76.32 74.19 43.33 65.71 35 70.91 69.23 74.07 41.18 28.57 59.38 78.72 68.42 61.76 46.88 72.88 55.77 67.39 56.9 78.72 63.27 75.34 65.52 78.43 71.74 55.56 56 63.77 71.43 58.73 72.06 82.61 60 72.73 52.94 72.22 62.5 50 77.78 100 72.73 75 70 55.07 69.81 56.52 40 81.4 59.38 35.71 70.21 62.07 42.11 71.67 76.77 65 75.44 79.37 64.52 57.14 64.29 75 87.5 71.43 59.68 61.25 100 65.62 83.33 18.75 72.58 100 66 55.88 63.27 34.78 56.76 53.85 71.19 62.69 66.67 67.27 76.56 18.18 75.76 60.87 69.77 74.19 55.81 44.12 68.52 85.92 75 100 58.49 16.67 44.12 57.78 63.64 65.52 100 63.33 100 71.05 80 70.18 100 46.88 16.13 62.07 38.18 68.75 40.54 80.88 68.52 48.28 79.01 42.65 53.06 63.49 57.41 49.21 60.47 68.42 45.1 72.58 56.6 62.03 48.84 70.83 65.52 36.31 -29.2 0.001461 0.035321 K cassette BRCC3 chrX + chrX:154319115-154344331 chrX:154319115-154327589;chrX:154327665-154344331 chrX:154327590-154327664 NA 18.46 21.21 10.71 13.64 NA NA 0 8.33 5.88 17.07 NA 0 5.88 31.82 23.08 9.52 0 40 0 15.79 9.09 28.12 15.38 17.39 12.9 NA 8.33 22.73 32 18.52 0 NA 22.73 6.56 40 8.33 17.65 8.11 24.39 10 3.03 10.71 9.09 10.53 9.09 9.52 20 12 7.41 22.64 32 0 17.65 16.28 17.65 0 9.52 17.86 20 11.11 NA 33.33 11.11 38.71 5.88 11.11 11.11 10 27.78 9.09 20.83 18.18 13.79 10.87 9.68 26.67 16.67 5.26 14.29 10 0 0 16.67 5 6.67 NA 30.77 14.29 21.74 NA 50 4 0 7.32 10 5.56 26.53 5.88 0 2.27 20 13.64 0 8.82 25 16.28 12.5 25 NA 0 6.67 11.76 NA 32 11.76 23.53 7.14 10 10.26 18.42 12.5 12.96 10.53 25 3.7 9.09 NA 15.94 11.76 2.22 0 18.75 0 4.76 6.9 0 0 7.14 NA NA 5.26 13.04 17.86 5.56 4 NA 6.67 NA 0 NA 5.26 15.62 5.56 6.25 10 18.18 0 4.35 27.78 25 NA 10.71 17.65 21.05 6.67 15.62 0 26.09 12.5 15.38 0 10.62 29.89 19.27 0.000137 0.006249 K cassette BTBD3 chr20 + chr20:11899250-11900365 chr20:11899250-11899733;chr20:11899825-11900365 chr20:11899734-11899824 NA NA 80 59.68 100 NA 100 45.16 44 76.47 NA NA 62.86 72 62.5 48.28 50 47.22 65.52 NA 57.14 NA NA 100 55.56 NA NA 73.68 71.43 54.17 80 75.61 100 61.54 56.25 38.89 70.97 63.33 100 42.86 45 100 68 62.86 NA 37.5 50 53.12 69.23 55.88 42.42 45.45 62.5 54.29 62.5 56.25 NA 75.76 72.97 65 86.11 62.96 65 54.55 73.53 70.37 77.08 68 100 57.14 71.43 82.05 60 70.83 NA 59.09 70 52.63 78.95 69.57 55 66.67 NA 57.89 63.64 100 NA 56.25 100 42.86 NA NA 69.44 100 48.39 NA 66.67 63.27 72.73 100 69.44 71.88 52.17 68.75 79.27 79.17 76.67 65.17 72.41 NA 73.08 62.75 62.96 NA 44 69.77 60 68.6 100 61.54 57.69 46.67 66.67 100 70.83 74.19 46.67 100 51.06 NA 65.38 100 100 100 NA NA 100 59.09 64.29 NA 100 100 NA 60.61 100 55.56 NA 50 NA NA NA NA 59.46 100 51.72 100 66.67 100 62.07 43.48 66.67 NA 72 62.5 50 61.11 67.35 73.91 69.57 67.86 45.83 45 66.67 43.48 -23.19 0.001102 0.024961 K alternative_acceptor BUB3 chr10 + chr10:124922345-124924562 chr10:124922345-124923335 chr10:124923336-124924562 chr10:124924562-124924563 64.75 61.45 70.07 76.69 63.32 50 75 74.84 42.77 79.78 61.76 41.74 50.43 62.99 62.65 56.67 41.22 75 51.98 33.06 45.97 40.19 65.92 60.98 42.19 46.26 53.67 44.26 46.43 50 49.31 65.24 54.5 63.44 52.86 25.19 58.61 47.01 54.05 29.88 49.43 81.48 53.77 58.26 59.13 48 40.77 60.94 53.11 58.82 57.94 30.25 45.04 70.48 42.7 47.14 72.22 65 58.33 49.14 58.62 67.29 59.55 44.59 63.4 42.21 60.87 66.96 53.49 58.2 56.72 49.54 67.65 50 56.02 58.27 56.31 42.94 71.15 58.96 54.95 58.25 42.57 52.73 61.5 51.8 71.3 61.64 66.09 48.6 57.33 44.55 70.92 60.16 53.49 59.46 63.92 61.08 54.82 60 61.89 61.48 41.33 55.31 64.92 48.63 59.02 79.76 50.64 48.39 51.8 50.32 55.86 70.97 48.17 53.85 42.79 60.29 59.15 61.63 53.02 64.2 49.31 65.79 56.7 44.88 44 67.95 52.23 61.22 64.77 69.93 57.39 80.24 53.72 53.97 62.46 72.34 64.12 71.43 58.16 64.8 63.41 60.27 53.27 62.73 48.28 63.7 51.55 27.17 51.11 66.67 54.88 48.41 52.38 56.69 62.12 48.15 63.43 28.41 51.43 62.11 45.95 59.22 50 36.46 57.65 51.85 57.21 73.37 42.86 56.64 57.33 30.06 -27.27 0.00117 0.047929 N alternative_acceptor BX538254 chr2 + chr2:179291233-179295496 chr2:179291233-179295421 chr2:179295422-179295496 chr2:179295496-179295497 100 100 87.23 100 100 100 NA 100 66.67 88.37 78.38 100 100 85.96 100 61.54 100 100 90.2 NA 100 100 100 76.67 100 100 100 100 100 78.79 81.48 100 100 85 83.93 NA 86.36 75.44 100 58.82 100 100 78.57 100 100 82.35 73.33 100 83.33 100 100 73.91 84.09 83.78 100 100 100 100 78.72 100 100 85.71 NA 81.58 83.67 100 87.27 70.27 100 66.67 100 75.86 82.69 67.86 100 71.88 100 100 81.63 75.61 100 100 100 77.42 100 72.46 100 70.97 80 81.82 100 66.67 100 100 72 100 100 76.79 84.85 75 81.43 81.43 81.48 100 84.44 70.45 85.45 80.26 70.83 100 76.47 100 100 100 80 70.18 71.43 100 100 100 71.79 81.63 82.14 72.73 100 100 100 100 84.44 100 100 100 82.14 100 100 100 100 100 100 NA 100 78.57 100 75.56 81.4 100 100 100 100 100 100 NA 74.29 100 78.57 100 87.93 100 80 65.38 85.96 100 66.67 83.67 100 100 86.11 87.5 84.09 71.05 100 100 100 66.67 -33.33 0.000101 0.00815 K cassette BZRAP1 chr17 - chr17:56402364-56403653 chr17:56402364-56402894;chr17:56403075-56403653 chr17:56402895-56403074 100 73.27 NA 79.17 100 NA 54.55 100 100 NA 100 100 76.47 NA 100 NA 71.67 67.44 69.57 NA NA NA 62.5 84.85 75 56.9 31.25 NA 73.91 100 57.38 75.86 68.83 57.14 NA 59.81 69.57 76.92 66.67 59.38 46.15 48.72 100 NA 58.33 81.48 NA 75 75 NA 63.64 NA 72.45 65.5 100 NA 56 70.44 NA 100 83.91 74.7 NA 78.69 68.75 68 100 61.76 100 57.58 NA 66.67 74.74 70.83 70 75.68 NA 70 NA NA 74.07 64.42 59.14 NA 75.93 NA 61.9 65.22 72.34 NA NA 45.83 79.55 NA 65 100 NA NA 58.82 74.71 100 69.86 NA 83.78 82.86 NA 60.71 NA NA 63.33 100 62.07 72.46 61.11 NA 73.24 NA NA 100 75 NA 82.98 54.17 65.62 80.7 63.83 76.19 NA 100 64.58 100 NA NA 100 NA NA 78.12 100 75 100 100 100 58.33 79.79 64.29 NA 63.11 78.09 NA 100 NA NA 76.79 74.07 65.37 69.81 NA 64.15 75 59.2 62.5 69.82 84.71 58.62 65.67 100 100 71.83 68.97 64.21 NA 59.38 73.91 59.2 -14.71 0.001967 0.039079 K cassette C11orf30 chr11 + chr11:76164433-76169226 chr11:76164433-76165792;chr11:76165835-76169226 chr11:76165793-76165834 NA 23.53 51.52 47.37 13.04 NA NA 54.55 28.89 31.91 37.14 NA 51.61 28.57 27.27 48.28 22.22 NA 33.33 14.81 36.67 0 57.89 43.48 46.67 0 30.77 14.29 29.73 18.75 46.67 36.84 NA 42.31 42.11 50 47.62 44.44 28.12 61.54 7.41 50 37.5 43.48 27.78 35 NA 37.68 44.44 41.18 28.33 73.91 50 60 29.41 9.52 NA 45.95 44.83 30.56 30 48.57 37.5 44.44 37.21 27.78 25 52.17 25.81 53.66 15 43.06 52.17 40.35 28 41.67 35 28.57 38.71 40.48 62.5 26.32 34.21 NA 25.49 27.27 36.76 32.14 40.74 36 34.29 44.12 37.04 44.44 32.43 47.06 52.38 18.75 25.49 45.16 42.31 35.9 28 25 45.24 32.35 37.14 30.77 0 47.37 18.42 25.71 18.84 61.11 6.67 46.67 32.35 45.83 63.16 40 38.89 41.18 30.43 44.44 40 23.81 11.11 42.31 29.79 18.42 42.11 25 16.67 48.39 31.25 NA 30.56 29.03 NA 25.93 NA 30.3 35.48 35.71 29.03 25 37.5 33.33 13.33 NA NA 27.27 48.28 20 35 27.66 41.18 25 37.74 59.46 28 14.29 51.85 30.43 36.36 40 28.57 26.32 40.74 37.25 32.35 43.48 35 56.56 21.56 0.000301 0.010892 K cassette C12orf11 chr12 - chr12:27067062-27068934 chr12:27067062-27067340;chr12:27067512-27068934 chr12:27067341-27067511 100 100 93.24 100 100 100 77.55 100 82 100 100 100 100 100 100 100 100 93.2 92.04 100 100 100 100 90.38 100 100 100 100 100 100 90.24 100 100 100 100 52.5 89.66 100 100 75.76 100 100 100 94.53 100 100 100 94.32 89.02 100 91.82 70.59 85.71 91.03 100 100 100 87.18 100 87.1 91.67 100 100 94.25 82.89 100 91.57 88.89 92.05 78.41 100 100 100 89.06 100 83.54 84.62 100 100 100 100 100 100 100 86.3 100 100 88.76 91.03 86.21 100 100 90.79 100 92.54 100 91.07 87.93 100 100 90.22 90.38 100 75.61 100 100 100 100 100 100 100 100 100 100 92.47 100 93.67 100 100 100 100 100 84.31 100 90.11 100 100 100 100 100 90.13 100 100 100 100 100 100 100 85.71 100 100 100 100 100 100 100 100 100 100 100 100 100 92.86 92.41 89.86 100 100 100 100 67.44 100 90 94.25 93.15 76.32 100 90.7 88.18 100 87.5 100 87.95 100 73.18 -26.82 0.00017 0.007265 K alternative_acceptor C17orf45 chr17 + chr17:16342729-16342973;chr17:16342729-16342894 chr17:16342729-16342841 chr17:16342842-16342894;chr17:16342895-16342973 chr17:16342894-16342895;chr17:16342973-16342974 50 63.85 42.57 54.02 48.45 50.86 42.55 53.23 75.71 31.88 38.97 NA 49.7 47.29 44.32 53.33 40 34.67 54.34 91.07 53.93 38.57 47.24 51.94 52.78 37.9 47.22 62.07 75.44 50.7 54.49 34.29 62.07 62.87 32.26 32.43 55 41.9 41.44 19.47 44.26 26.47 36.54 46.79 51.67 70.27 42.75 54.39 35.63 36.03 94.55 42.06 42.91 35.32 68.52 43.48 62.13 52.63 50.43 46.39 45.5 42.86 55.7 26.22 58.25 52.43 51.62 49.57 53.39 20.78 44.97 51.38 48.86 50.87 21.31 57.51 65.85 49.78 36.07 38.55 49.66 41.32 35.42 49.66 50.27 64.68 35.25 54.55 39.31 54.42 32.1 21.8 31.55 54.37 47.62 55.56 13.21 48.61 46.72 65.75 46.98 46.55 54.66 64.71 40.18 40.82 41.7 48.25 47.75 49.23 56.96 63.03 34.78 35.42 41.1 41.48 48.72 45.58 50 49.15 46.77 46.88 32.82 44.78 45.15 41.67 50 19.23 48.84 41.46 40.53 36.9 56.68 37.97 50.81 51.83 53.64 32.89 34.47 88 44.93 34.2 38.16 48.48 59.87 65.52 46.61 42.38 34.96 90.7 44.84 61.4 40.14 47.79 53.98 46.6 39.35 82.05 29.71 33.05 52.38 34.23 45.61 44.2 40 36.26 46.67 50.12 44 43.97 61.02 39.9 47.45 27.12 -20.34 0.000481 0.026453 K alternative_last_exon C20orf43 chr20 + chr20:55043823-55048356 chr20:55043823-55045655 chr20:55048357-55048451 chr20:55045656-55046003 12 3.81 5.32 4.31 6.67 6.45 11.03 4.29 6.84 5.41 3.88 2.78 5.26 4.26 2.88 7.14 10 5.56 3.4 2.5 3.49 4.26 5.17 4.4 6.9 2.34 8.7 2.86 6.06 5.26 5.56 3.66 14.29 10.91 5.49 13.79 8.51 2.86 7.89 19.12 9.68 9.72 4.67 7.55 10 8.7 1.98 5.66 5.56 2.5 8.66 16.42 3.57 5.83 5.06 1.79 1.04 6.67 3.57 3.75 4.41 9.8 7.32 8.82 3.97 6.12 5.41 3.96 5.31 18.1 6.45 7.5 4.49 7.61 9.09 3.33 14.06 4.71 3.39 3.91 6.76 16.85 5.88 5.06 11.43 5.17 15.32 8.47 5.07 2.41 12.33 14.89 4.84 4.55 7.34 3.85 5.68 7.56 11.24 11.61 2.53 6.29 3.5 5.33 10.99 4.55 5.38 1.35 4.43 4.29 7.03 7.69 12.04 6.9 1.41 7.3 6.85 10.32 9.88 5.3 3.39 3.55 5.92 7.1 5.21 7.34 5.26 13.64 1.89 7.89 4.55 0 3.25 5.19 4.23 3.52 4.2 11.27 7.07 10.59 6.58 4.6 4.12 7.01 7.95 5.75 4.35 3.17 14.29 11.94 1.22 10.53 5.43 9.09 7.69 22.54 3.39 7.41 6.85 20.75 4.04 14.86 4.4 7.14 6.59 3.12 2.9 4.71 4.3 11.54 16.67 5.48 5.49 17.26 11.77 0.000065 0.021773 K alternative_acceptor C3orf17 chr3 - chr3:112730013-112731580 chr3:112730254-112731580 chr3:112730013-112730253 chr3:112730012-112730013 100 100 100 87.5 100 NA 100 100 100 100 100 NA 100 100 100 100 100 100 80.49 100 100 100 100 100 100 100 100 100 100 83.87 100 100 100 100 100 76 100 100 100 84.85 100 100 100 100 100 100 100 100 100 90.38 100 100 100 100 83.87 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.64 100 100 100 100 100 85.42 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 85.19 100 100 100 100 100 100 100 100 100 100 86.27 90.2 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 84.21 100 100 100 100 100 84.62 100 100 100 100 100 100 100 100 100 100 100 100 100 86.75 -13.25 0 0.000021 N alternative_acceptor C3orf23 chr3 + chr3:44403011-44409023;chr3:44403011-44403911 chr3:44403011-44408947 chr3:44403912-44408947;chr3:44408948-44409023 chr3:44408947-44408948;chr3:44409023-44409024 NA 16.67 39.02 5.26 34.62 NA NA 10.81 27.27 40.54 48.57 NA 11.11 8.33 15.38 NA 31.58 25 29.73 NA 16.67 NA 30.23 10 38.46 15.79 52.63 NA 15.38 15.79 16.67 17.39 NA 13.04 27.78 0 12.12 31.03 38.89 10.53 NA 20 21.43 33.33 NA 10 27.27 44.44 11.54 15.79 NA 0 12 31.58 18.75 21.43 NA 17.86 37.21 29.03 25 20 27.78 25.81 28.12 7.14 14.89 13.33 36.36 9.38 38.89 NA 12.12 13.64 20 30.77 25 30.77 37.14 21.43 21.05 11.76 43.75 NA 16.67 10.71 NA NA 25 29.63 NA NA 40.48 35.9 20 NA NA 28.21 26.67 NA 32.43 13.64 40 18.18 25 30.43 33.33 34.48 NA NA 30.3 21.43 0 NA 21.05 25.71 28 NA 15 18.75 28.12 39.29 14.29 29.41 25.64 NA 21.05 12 26.92 10.53 10.81 19.44 21.74 13.64 NA 33.33 19.05 15.79 NA NA 15.79 NA NA NA 17.39 0 NA 19.05 NA NA NA NA 26.67 12.5 33.33 0 29.17 15.38 30.77 12.5 30.43 32 27.27 28.57 0 20 30.77 13.51 29.03 29.03 21.43 34.78 21.74 9.38 -12.36 0.001032 0.043622 K alternative_acceptor C3orf63 chr3 - chr3:56657595-56658506 chr3:56657872-56658506 chr3:56657595-56657871 chr3:56657594-56657595 100 87.18 91.73 100 94.57 100 100 100 100 100 91.67 100 100 94.12 84.11 92.42 88.24 100 100 100 92 100 100 92.31 86.84 100 100 90.36 100 100 88.33 100 100 100 90.42 74.51 93.26 90.57 93.07 84.29 100 96.24 100 91.2 89.87 100 100 89.29 100 83.13 77.92 79.03 100 100 100 90.41 100 100 100 92.54 100 100 92.96 100 100 100 91.78 89.19 100 90.91 100 100 88.89 91.75 100 92.68 93.98 89.74 91.55 88.51 100 100 100 100 100 100 100 90 95 89.04 100 84.21 91.76 100 92.55 100 100 90.54 92.63 100 92.06 92.66 91.03 100 100 86.61 91.96 91.96 90.2 100 90.36 88.61 100 100 100 100 87.06 90.32 100 100 94.38 93.27 100 100 90.65 100 100 100 90.52 91.84 92.31 85.33 80.77 100 86.11 100 100 100 100 100 100 90.36 100 100 90.36 94.62 100 90.1 100 100 100 100 87.95 100 90.38 100 100 100 92.68 87.14 100 91.67 100 100 100 78.21 91 100 91.26 100 91.94 100 100 84.25 -15.75 0.000056 0.005042 K alternative_acceptor C3orf63 chr3 - chr3:56667872-56672733 chr3:56667995-56672733 chr3:56667872-56667994 chr3:56667871-56667872 100 84.95 78.02 85.48 77.19 NA NA 79.01 92.06 91.67 71.43 100 75 79.71 82.98 80.28 92.75 86.25 75.68 100 82.14 60 86.76 72.46 72.97 100 68 70.97 72.22 83.58 83.08 76.39 100 100 69.83 60.78 88.89 78.31 80.28 63.24 80.49 75.82 63.93 77.27 80 78.57 70.37 79.22 68.49 81.33 87.04 75.56 78.12 79.69 67.53 68.09 100 79.1 73.33 75 80.6 84.31 80.88 67.27 72.15 68.75 75 66.67 71.88 63.22 79.69 74.36 82.61 73.56 70.37 76.92 83.87 72.22 78.12 67.95 100 86.49 86 69.77 71.21 100 100 67.74 73.21 80.33 100 53.49 65.22 78.12 74.29 84.13 100 85.71 70.77 100 69.88 70.53 100 74.42 82.54 84.38 73.68 63.72 67.65 78.33 80.6 67.47 77.27 100 70.89 83 83.13 100 100 77.38 81.72 74.19 80 76.25 73.81 75.44 84.44 72.31 73.81 80.72 77.65 100 78 89.23 78.12 100 82.02 85.19 85.14 82.14 100 100 100 77.46 83.33 76.29 80.77 84.93 100 100 100 82.35 81.08 86.54 84.44 77.27 70.67 79.17 83.33 57.33 78.87 77.55 85.53 67.27 67.21 83.02 79.73 69.09 69.57 69.44 69.64 83.67 79.17 62 -17.17 0.000246 0.017525 K cassette C3orf75 chr3 - chr3:47545939-47552637 chr3:47545939-47551673;chr3:47551745-47552637 chr3:47551674-47551744 100 100 85.37 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.1 100 100 100 100 100 100 100 100 85.29 100 100 75.86 100 100 100 100 100 100 100 100 100 82.76 100 82.76 87.8 100 100 100 100 100 83.33 100 100 100 100 100 100 100 82.14 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 52.63 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.24 89.58 100 100 100 100 100 100 89.58 100 100 100 NA 100 100 100 100 100 79.31 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 87.76 100 100 100 100 100 100 100 100 100 84.85 100 100 100 100 100 76 100 100 100 100 100 100 100 100 100 100 70.59 100 100 79.38 -20.62 0.000001 0.000076 N cassette C4orf29 chr4 + chr4:128905579-128930074;chr4:128910977-128930074 chr4:128910977-128922870,chr4:128905579-128922870;chr4:128922916-128930074 chr4:128922871-128922915 NA 23.08 13.33 21.74 0 NA 0 25.71 9.3 25 6.98 NA 28 0 12.9 7.41 37.5 6.38 18.42 0 11.54 0 20 17.95 18.18 0 0 10.34 30.77 13.33 37.5 12.9 0 0 9.09 28.57 0 0 11.76 34.62 23.08 22.22 12.9 0 NA 13.51 NA 17.86 0 18.18 29.55 33.33 0 8.16 13.79 16.67 0 8.82 12.82 0 20.51 20.37 18.92 25.93 30.77 0 17.39 15 0 15.38 27.03 29.63 13.51 28.89 26.67 18.52 8.33 16.67 22.86 11.11 20 17.5 8.82 0 20.83 0 NA 23.53 14.29 5 0 19.05 0 30.77 19.35 0 11.54 0 24.24 21.43 20 26.09 20 27.78 27.27 12.82 0 8.2 14.81 0 14.29 20.69 8.82 0 9.3 8.33 24 4.41 17.65 20 25 11.11 24.24 24.53 6.67 0 0 31.25 19.05 22.22 11.11 18.18 0 0 0 0 0 0 0 0 13.64 17.86 NA 0 0 12.5 0 0 0 NA NA 0 10.53 22.5 28 8.33 11.43 11.76 5.26 41.46 8 14.29 0 25 0 NA 10 7.41 17.24 10.26 12.5 11.54 11.76 30.95 19.19 0.001593 0.033035 K cassette C5orf37 chr5 - chr5:74970404-74981031 chr5:74970404-74973598;chr5:74973776-74981031 chr5:74973599-74973775 100 100 100 100 100 100 60.98 100 100 100 100 100 100 100 100 100 82.86 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92 86.11 100 100 100 100 100 100 100 100 100 100 100 100 80 100 100 100 100 100 100 100 100 100 82.5 100 100 87.5 100 100 100 100 90.67 84 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 86.27 100 81.48 100 100 100 100 100 85.29 100 NA 100 100 100 100 100 79.07 87.5 100 100 100 100 100 100 100 100 100 100 100 100 100 100 91.07 100 100 100 89.13 100 100 86.49 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 84.21 100 100 100 100 100 100 100 100 100 100 100 100 100 87.44 -12.56 0.000001 0.000071 K alternative_acceptor C6orf89 chr6 + chr6:36867410-36870055 chr6:36867410-36869996 chr6:36869997-36870055 chr6:36870055-36870056 100 100 100 100 100 NA 100 100 91.53 72.55 100 100 100 100 100 100 78.95 100 100 100 90.91 100 100 86 100 100 100 100 100 100 100 87.18 100 100 100 80.56 100 100 100 100 100 100 100 100 100 100 100 92.75 100 100 86.11 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 80.49 89.13 100 100 100 100 100 100 100 100 100 100 100 100 100 73.53 100 100 91.07 85.71 100 100 71.88 100 100 100 100 100 100 86.49 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 91.78 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92.19 100 100 100 100 100 100 100 100 100 100 76.19 100 NA 100 100 100 83.33 73.33 100 100 100 100 89.58 87.27 100 100 100 100 100 100 100 100 88.37 74.07 100 100 100 83.91 -16.09 0.000087 0.007196 N cassette CAPN7 chr3 + chr3:15282361-15283684 chr3:15282361-15282959;chr3:15283096-15283684 chr3:15282960-15283095 NA 55.77 75.68 60.71 56.52 NA NA 100 74.29 69.39 60.98 NA 61.11 57.89 100 78.26 62.16 66.67 70.59 58.06 53.66 100 52.94 75 55 38.89 61.54 75 67.86 58.14 63.41 65 100 100 64.44 41.67 57.14 59.46 71.43 36.67 51.85 51.72 65.62 100 33.33 71.43 68 68.85 76.19 59.52 58.21 41.18 54.17 76.19 68.75 56.25 42.11 65.79 51.22 54.55 51.28 50 54.29 61.76 79.17 36.36 60 61.54 66.67 55.81 56.25 53.33 61.76 57.14 69.7 64.52 51.43 61.9 66.67 63.16 46.67 56.67 77.42 72 56.67 100 100 70.27 100 57.78 28.57 35.71 43.18 100 45.95 35.29 54.05 43.59 60.53 53.12 68 57.78 57.14 43.33 68.75 69.7 72.41 71.7 57.45 52.94 47.37 67.65 63.89 NA 70.59 65.22 65.52 77.14 100 49.21 58.33 65.22 75 51.43 51.61 75 70.59 75 55.81 56.41 100 100 72.22 100 100 100 43.75 51.72 62.86 50 100 54.29 NA 69.23 51.28 61.22 61.11 57.14 NA 100 NA 100 56 72 53.12 51.43 63.33 64.29 43.75 54.55 51.72 100 62.86 62.16 63.64 71.43 81.48 67.65 66.67 68.42 58.82 62.5 62.68 41.42 -21.26 0.001049 0.024203 N cassette CARD10,MFNG chr22 - chr22:37876338-37881960;chr22:37876338-37881985;chr22:37876338-37881953 chr22:37876338-37876758;chr22:37876808-37881953,chr22:37876808-37881985,chr22:37876808-37881960 chr22:37876759-37876807 100 91.43 100 100 100 92.98 90.29 100 95.02 95.27 100 100 100 100 100 94.41 82.69 89.69 100 100 95.48 100 100 95.71 100 95.68 100 97.4 95 100 94.37 100 100 100 100 84 100 94.22 95.65 76.43 100 100 92.42 91.15 100 90.65 97.44 92.35 94.21 95.06 95.36 93.9 100 100 93.33 95.24 100 100 95.87 96.13 100 100 100 100 96.12 90 91.75 96.55 100 83.08 95.59 96.17 100 92.99 93.6 96.24 100 100 91.78 95.35 100 100 88.54 100 94.95 88.89 86.71 97.35 95.65 97.22 100 87.72 100 100 87.63 100 100 95.57 100 93.16 100 92.39 95.83 93.97 90.26 91.71 97.73 91.82 93.02 90 94.67 89.47 87.86 97.74 82.51 97.48 94.49 92.57 100 94.09 95.45 94.27 95.41 90.15 95.58 94.15 95.3 100 100 88.57 92.13 100 100 100 100 100 100 100 100 100 100 93.41 85.56 97.92 100 95.28 100 100 94.2 100 100 100 100 85.85 100 100 100 100 92.17 88.17 84.21 100 94.84 100 94.02 95.24 100 100 96.3 94.7 80.3 100 97.4 85.86 -11.54 0.000112 0.005287 N alternative_acceptor CARD8 chr19 - chr19:48745902-48752779;chr19:48749639-48752779 chr19:48744321-48752779 chr19:48744321-48745901;chr19:48745902-48749638 chr19:48744320-48744321;chr19:48745901-48745902 71.43 58.14 52.38 78.12 68.48 90 86.96 56.25 60.44 57.32 65.17 61.22 54.32 52.48 73.81 70.87 70.15 45.74 71.08 78.79 59 67.74 55.26 77.78 54.55 82.69 56.25 81.36 74.26 65.35 70 54.81 63.77 79.75 60.92 48.48 64.44 76.85 58.33 31.37 59.76 54.84 68.09 62.64 72.86 65.79 80 73.64 70.11 64.81 75.31 52.63 70.91 72.73 82.81 71.76 75.47 74.19 61.8 79.75 64.66 61.43 54.37 67.86 70.42 68.33 65.43 69.01 67.05 42.64 68.18 60.23 62.04 48.84 77.69 75 56.12 61.11 47.22 73 67.39 61.11 72.84 66.13 67.41 74.67 61.8 72.29 75.68 61.54 55.88 19.28 60 68.14 55.32 52.69 66.35 67.24 55.75 58.9 69.23 65.66 72.97 61.73 63.16 45.39 63.21 63.33 67.24 64.52 70.65 58.33 66.34 43.1 68.82 58.64 72.73 48.58 66.67 62.18 63.06 71.43 75.82 73.33 68.54 64.03 63.64 55.74 66.67 60.32 69.51 78 56 62.39 40.82 78.31 62.86 80.88 63.33 39.66 68.42 41.18 70.59 87.96 67.8 72.07 66.67 53.54 70.69 50 NA 88.89 56.18 80.77 79.69 65.93 64.1 65.22 83.65 40.62 62.5 64.52 68 74.32 88.46 69.23 70.1 59.43 62.9 67.5 62.3 75 66.51 41.63 -24.88 0.000068 0.005926 K alternative_acceptor CASP8 chr2 + chr2:202098836-202131209 chr2:202098836-202131183 chr2:202131184-202131209 chr2:202131209-202131210 NA 100 76 100 77.27 NA 100 100 100 100 100 100 100 100 100 NA 100 100 100 NA 100 100 NA NA NA 100 NA NA NA NA 100 100 100 65.22 100 NA 100 83.78 100 40.91 NA 100 100 100 100 61.11 NA 66.67 100 100 100 53.85 NA 100 NA 100 NA 100 100 100 100 NA 100 NA 100 NA NA 100 100 48.39 100 100 69.57 100 100 NA 100 NA 100 100 NA 100 NA NA 100 100 100 100 100 NA 100 NA 100 100 100 100 100 100 100 100 73.33 100 100 100 65 100 76.92 68.09 100 NA 77.42 100 100 100 100 100 NA 100 100 100 77.42 84.62 100 100 100 NA NA NA 100 100 100 100 100 100 100 NA 100 100 83.33 100 100 100 100 100 NA 100 NA 100 100 NA NA 100 75 NA NA NA 100 NA 100 57.14 100 100 100 NA 100 NA 75 100 74.07 NA NA 100 100 51.12 -48.88 0 0.000076 K cassette CBWD1 chr9 - chr9:175785-178815 chr9:175785-177722;chr9:177821-178815 chr9:177723-177820 15.28 17.44 26.83 12.5 19.35 26.15 23.33 19.53 18.26 38.33 17.78 100 23.76 18.68 11.96 17.5 29.3 22.67 11.59 34.21 21.83 20.65 14.55 26.4 37.23 7.53 17.42 19.42 27.56 26.19 22.71 19.69 20.62 20 19.83 27.12 21.98 22.18 25.19 36.54 23.21 18.82 38.97 31.63 22.22 20.25 20.91 18.34 17.78 39.36 15.14 33.91 21.5 17.68 13.16 31.06 12.86 35.82 25.22 20.96 28 28.7 26.21 22.76 15.44 15.73 30.63 20.57 22.11 33.33 23.31 23.12 23.24 30 16.86 24.11 19.27 15.74 28.21 21.47 24.07 26.37 25.98 22.3 22 9.52 18.71 26.82 23.33 13.44 38.57 33.33 15.22 15.52 16.94 17.54 23.96 15.07 16.54 41.28 24.69 22.54 21.91 24.81 19.89 17.88 21.95 20.61 22.22 16.25 21.66 16.08 20.25 14.81 17.33 31.74 27.59 9.09 23.47 36.27 15.79 25.15 19.29 18.05 15.46 20.26 19.08 24.6 31.28 18.99 21.01 13.39 21.43 29.03 18.29 18.6 17.44 31.82 18.87 17.39 13.49 17.27 17.86 20.45 6.92 25.22 20 27.07 9.09 21.19 9.68 30 29.49 19.89 18.94 26.83 23.75 14.58 38.3 30.89 22.42 14.39 25.13 20.95 8.57 19.8 18.23 15.51 21.18 26.04 31.03 17.59 20.91 33.33 12.42 0.000429 0.013647 K cassette CBWD1,CBWD2 chr2 + chr2:114195600-114198927 chr2:114195600-114196596;chr2:114196695-114198927 chr2:114196597-114196694 19.05 33.78 32.61 26.67 23.53 25 19.67 25 18.52 52.54 19.75 NA 27.59 30 17.7 13.51 33.73 29.73 10.32 45.95 26.39 27.08 12.96 31.51 46.34 6.1 12.5 22.13 40 36.36 27.59 31.67 20.45 20.9 21.13 30.56 27 24.4 36.36 50 29.79 19.61 39.76 29.51 32.89 23.75 24.14 27.27 21.92 46.81 19.05 36.84 27.59 18.45 18.31 34.57 22.22 40.96 25 28.57 32.2 32.47 30.91 18.75 19.67 15.52 37.93 21.43 34.55 38.81 26.83 28.16 24.44 37.88 22.97 30.91 16.67 15.13 33.85 20.37 23.88 27.78 35.48 27.85 26.32 16.67 21.36 28.7 26.67 13.79 35.48 42.03 16.42 17.91 17.78 19.12 23.81 16.94 17.86 40.98 26.77 30.11 25 29.58 20.16 18.09 21.65 24.3 23.57 16.67 25 16.18 22.68 28.57 17.78 36.96 30.77 11.27 29.31 40.5 16.22 23.42 21.95 19.12 18.28 25.74 23.61 26.92 34.51 34.29 20.55 18.31 25.61 42.86 28.95 30.26 18.81 31.67 28.57 11.63 11.54 21.05 10.71 19.28 5.75 29.94 27.27 26.51 12.77 16.39 10.53 33.33 34.02 21.74 24.24 33.82 24.75 17.39 48.15 35.48 18.33 13.27 30.63 22.92 16.67 22.33 19.15 16.96 26.74 31.36 42.11 21.31 24.35 37.83 13.48 0.000622 0.016488 N alternative_acceptor CBX6 chr22 - chr22:39263153-39267484 chr22:39263207-39267484 chr22:39263153-39263206 chr22:39263152-39263153 NA 100 NA 100 NA 100 100 NA 87.93 100 100 NA 84.62 NA NA 84.85 100 100 100 100 100 NA 100 89.87 84.21 100 100 100 100 90.2 100 NA 100 100 100 86.11 100 100 100 86.11 100 100 100 100 100 100 87.3 86.49 100 87.8 86.67 86.05 72.73 100 100 100 NA 90.74 100 83.93 100 100 100 100 100 NA 100 100 100 72 100 100 NA 79.07 100 100 100 85.71 100 100 100 100 100 100 80.77 NA 100 100 100 80 83.87 NA 100 NA 100 NA NA 86.79 100 86.72 100 79.31 100 84.91 100 79.17 79.03 100 100 100 100 90.79 81.48 NA 100 100 100 100 100 100 85.71 100 100 100 NA 85.32 100 NA 100 100 100 100 100 100 100 100 100 100 100 NA NA 100 100 100 100 100 100 100 81.67 100 100 100 100 100 100 84.62 100 78.12 100 82.05 100 100 100 100 83.87 81.25 84.21 100 100 100 75.86 100 100 86.05 -13.95 0.000148 0.01132 K cassette CCDC111 chr4 + chr4:185580592-185587070 chr4:185580592-185582927;chr4:185583058-185587070 chr4:185582928-185583057 NA 85.11 100 100 100 100 NA 100 77.27 100 100 100 100 100 100 NA 100 89.13 100 100 100 100 100 100 100 NA 100 100 100 100 100 81.08 100 100 100 73.68 82.5 100 100 76.19 100 87.23 100 100 100 84.62 100 86.05 100 85.29 100 100 100 100 100 100 100 100 89.13 81.08 100 100 100 100 100 100 85.71 77.42 100 83.33 100 100 76.74 100 100 100 100 100 100 100 100 100 100 100 86.11 77.5 100 100 100 100 100 100 100 100 100 100 100 100 85 100 89.58 80.95 100 100 85.29 100 100 100 100 100 100 100 100 100 85.29 100 100 100 100 100 100 77.19 100 100 85.71 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 84.62 100 100 100 100 82.76 79.31 100 100 85 100 100 100 86.49 100 100 100 81.82 100 100 81.32 -18.68 0.000523 0.014823 N cassette CCDC18 chr1 + chr1:93649053-93651901 chr1:93649053-93649534;chr1:93649704-93651901 chr1:93649535-93649703 100 100 100 100 100 NA NA 100 100 100 100 NA 100 100 100 100 83.78 100 100 NA 77.27 NA 100 100 NA NA 100 100 100 100 100 100 100 NA 100 64.29 100 100 100 50 100 100 100 100 100 100 NA 100 100 100 100 44.44 100 100 100 100 100 100 100 100 100 79.41 100 100 100 100 100 80 100 72.22 78.79 100 100 82.05 100 100 100 100 100 100 100 100 82.05 100 100 NA 100 100 100 66.67 NA 73.33 100 100 100 100 100 62.16 100 100 100 100 53.85 100 100 100 100 72.73 100 100 NA 100 100 NA 100 100 70.59 100 100 100 100 100 100 86.84 80 100 100 100 79.31 100 100 100 100 100 100 NA 80 NA 100 NA 100 100 100 100 100 100 100 100 NA 100 NA NA 100 100 100 100 100 73.68 100 50 100 100 81.48 100 78.26 NA 100 73.68 100 100 100 100 100 57.15 -42.85 0 0 N alternative_donor CCDC53 chr12 - chr12:102411584-102419751 chr12:102411584-102413054 chr12:102413055-102419751 chr12:102419751-102419752 100 100 100 100 100 NA NA NA 100 100 100 100 100 100 NA 100 100 100 100 NA 100 100 100 100 NA NA 100 NA 100 100 100 100 100 100 100 52.94 100 100 100 60 74.07 100 100 100 57.69 100 NA 100 100 100 100 100 NA 100 100 100 100 100 100 100 87.18 100 100 100 100 100 100 100 100 100 100 100 100 100 80 100 100 NA 100 100 100 100 100 NA 100 100 100 57.14 100 NA 100 36.36 100 100 80.56 100 100 100 100 NA 78.79 78.05 NA 100 100 100 86.11 100 NA 100 76.19 100 100 100 100 100 73.68 100 100 100 100 100 100 100 100 NA 100 100 72.22 100 64.29 100 100 100 100 NA 72.97 100 100 100 100 100 100 100 100 100 100 100 NA NA NA NA 100 100 NA 100 100 100 100 75 100 100 100 100 NA NA 100 100 100 100 100 NA 100 67.5 -32.5 0.000014 0.010069 N alternative_acceptor CCDC76 chr1 + chr1:100606071-100606400;chr1:100606071-100606420;chr1:100606071-100606407 chr1:100606071-100606522 chr1:100606401-100606407;chr1:100606408-100606420;chr1:100606421-100606522 chr1:100606407-100606408;chr1:100606420-100606421;chr1:100606522-100606523 NA 27.59 29.41 37.5 0 NA NA 0 0 20 0 NA 0 0 0 21.21 25.71 43.24 40.54 NA 0 0 0 46.43 NA NA 0 56.25 33.33 0 0 29.63 NA NA NA 69.57 40.62 24.32 33.33 66.67 50 19.44 20.83 26.67 35.71 44.44 NA 25 0 37.5 0 58.33 64.29 20.83 29.41 NA NA 20 28.57 29.63 36.59 48.48 NA 0 23.53 27.27 31.03 34.62 41.94 38.46 27.78 17.65 26.23 45 35.9 22.58 45 31.25 25 33.33 64 31.03 0 45.45 51.72 0 NA 43.75 41.18 0 NA NA 28 0 28.57 NA 0 60.87 33.33 NA 29.55 28.57 NA 0 56.52 0 33.33 25.71 41.18 NA 37.14 39.13 37.25 NA 16.22 26.32 32.5 36.36 NA 29.73 11.9 40 33.33 51.16 0 NA 0 37.5 38.46 NA 0 NA 0 34.38 NA NA 0 0 NA NA NA NA NA 37.5 36.67 0 NA 0 NA NA NA NA 31.82 0 52.94 37.5 20 40.91 26.83 66.67 44.83 NA 12.82 26.09 NA NA 0 33.33 30.3 38.46 0 0 28.57 66.67 38.1 0.000589 0.028359 K cassette CCNH chr5 - chr5:86697590-86703792 chr5:86697590-86700660;chr5:86700825-86703792 chr5:86700661-86700824 100 100 100 100 100 100 100 100 100 100 100 100 100 94.83 100 100 89.43 100 100 100 100 100 100 100 100 100 100 100 100 100 87.69 100 100 100 100 100 94.62 92.91 100 85.71 100 92 100 94.57 100 80 100 100 100 100 100 91.46 100 93.57 100 100 100 100 94.38 100 93.27 90.11 96.84 93.06 100 100 92.94 90.41 95 89.55 100 100 91.54 100 94.2 100 90.16 96.5 94.51 91.38 100 100 100 100 100 100 100 100 100 100 100 80.81 100 100 94.7 95.28 100 92.68 95.54 100 94.04 92.8 100 100 100 88.66 93.51 89.05 100 100 100 95.28 92.41 100 100 93.15 93.33 100 100 100 82.02 93.53 100 92.37 91.21 100 92.96 91.67 100 89.13 100 100 100 100 100 100 100 90.43 100 100 100 100 100 100 100 91.18 100 100 100 87.83 100 100 92 100 100 94.74 93.14 90.62 92.08 87.18 100 100 100 93.98 100 100 100 100 94.85 93.52 100 100 100 88.37 -11.63 0.000355 0.012303 K cassette CD300LF chr17 - chr17:72691999-72694507;chr17:72691999-72699173 chr17:72691999-72692333;chr17:72692357-72694507,chr17:72692357-72699173 chr17:72692334-72692356 NA 100 80.65 100 80.43 69.7 24.39 80 76.76 100 80 100 56 69.23 77.78 83.02 37.74 100 100 100 75.37 100 79.09 79.37 72.5 87.13 100 79.66 82.96 86.43 65.66 70.59 100 NA 100 43.59 76.81 65.22 77.11 59.26 74.19 35.71 69.09 62.07 77.61 88.72 80.39 100 83.72 70.18 75 59.68 NA 69.7 73.68 78.85 100 65.12 75.68 86.27 58.33 34.78 69.29 71.43 76.09 NA 66.67 63.64 74.19 55.93 71.83 83.61 66.67 73.08 71.81 76.62 68.75 82.35 46.67 67.74 100 68.57 100 52.5 73.08 NA 44.44 60.17 NA 84.21 47.92 56.25 80 100 65 80 100 56.25 53.85 78.82 81.56 72 64.92 80 72.41 72.22 80 70 69.71 72.73 79.59 84.85 NA 71.43 NA 66.38 80.77 NA 77.27 81.97 71.21 54.1 69 54.79 66.67 72.07 83.33 82.14 82.93 25 74.63 NA 90.2 63.04 70.18 87.5 80 63.33 53.33 62.96 100 66.67 100 100 NA 72.35 NA 76.6 NA 70.93 100 100 61.9 100 100 66.67 57.58 82.86 59.57 53.62 100 NA 66.67 NA 70.37 65.12 77.27 NA 72 83.81 NA NA 76.09 56.09 -20 0.000549 0.015152 N coord_cassette CD53 chr1 + chr1:111437024-111441745 chr1:111437024-111439274;chr1:111439356-111440430;chr1:111440515-111441745 chr1:111439275-111439355;chr1:111440431-111440514 100 100 97.44 87.44 94.42 87.42 61.21 91.52 97.1 100 100 100 100 100 100 97.48 93.23 94.19 97.87 100 98.38 100 100 92.86 94.78 96.41 100 95.52 100 99.02 100 100 100 95.92 100 83.09 97.23 94.69 96.22 85.29 94.46 100 97.52 100 95.55 96.83 97.33 96.23 96.32 96.73 97.34 89.66 100 100 100 97.08 91.28 96.91 100 97.16 94.23 100 100 96.69 96.64 92.75 94.41 92.47 98.02 91.38 96.39 90.31 100 97.27 93.99 100 89.96 97.59 100 95.05 97.37 100 100 93.64 100 100 100 93.1 87.78 98.58 100 81.39 100 95.85 97.05 97.96 93.53 85.3 97.32 96.14 97.86 100 96.64 93.05 92.09 95.38 100 95.47 95.9 100 96.65 95.25 93.77 100 100 100 97.19 96.69 100 95.27 96.06 95.32 97.42 92.54 97.14 95.45 95.72 100 97.84 92.71 100 100 100 100 100 100 100 100 100 100 93.44 100 100 95.54 100 97.14 93.83 96.84 95.15 100 100 100 96.79 93.64 90.94 100 100 95.54 87.92 87.07 94.94 100 97.26 96.72 82.59 96.68 95.69 96.19 97.2 95.5 93.24 100 97.23 86.18 -11.05 0.000056 0.002794 N cassette CD53 chr1 + chr1:111435156-111441745;chr1:111439356-111441745;chr1:111437024-111441745;chr1:111437678-111441745 chr1:111439356-111440430,chr1:111437024-111440430,chr1:111435156-111440430,chr1:111437678-111440430;chr1:111440515-111441745 chr1:111440431-111440514 100 96.32 92.81 75.48 92.49 65.45 46.68 87.54 93.47 97.7 95.92 100 92.38 95.79 95.69 94.49 93.97 90.05 94.71 95.29 95.78 100 96.77 85.84 91.09 92.45 100 91.46 95.92 96.92 93.41 95.83 100 93.72 96.46 67.8 93.4 88.85 92.68 75.72 92.97 100 93.44 100 95.87 87.14 94.01 88.51 93.89 93.47 92.17 84.27 94.26 96.45 94.84 92.24 94.62 96.3 98.56 93.65 91.3 100 96.38 91.89 92.99 89.8 86.26 87.25 93.1 85.8 91.72 86.18 92.37 91.48 91.58 97.52 86.68 92.95 100 87.4 90.88 100 95.57 87.79 94.07 94.43 100 82.96 77.91 94.32 97.96 78.42 96.38 97.49 93.59 92.5 96.04 76.21 94.3 91.39 92.61 95.68 91.15 87.77 88.12 91.34 93.13 92.36 93.38 96.42 94.67 88.93 90 100 96.79 92.79 92.23 91.56 92.77 92.09 87.61 89.04 92.21 91.09 92.32 88.02 92.69 98.37 94.69 88.95 100 95.19 97.58 92.81 96.57 97.74 91.53 91.72 100 91.79 90.21 100 100 89.09 96.38 93.89 89.9 90.64 87.37 97.5 100 98.35 95.27 85.56 83.72 96.91 91.18 90.54 82.59 80.28 91.87 92.32 92.17 92.84 76.84 93.17 94.39 92.68 89.69 90.36 92.4 93.56 92.95 79.35 -13.6 0.000122 0.005705 K cassette CDC27 chr17 - chr17:45247409-45258927 chr17:45247409-45249282;chr17:45249431-45258927 chr17:45249283-45249430 NA 100 100 100 100 NA 53.33 100 100 100 78 100 100 100 100 100 89.23 100 100 100 89.47 100 100 84.31 82.14 100 100 81.08 88 100 93.75 100 100 74.58 100 86.79 100 90.91 87.27 83.05 100 100 85 100 100 100 100 100 100 88.73 100 80 100 90.74 100 86.49 80.77 100 100 100 89.83 84.13 85.45 90.74 87.88 100 100 81.48 88.89 84.51 100 100 100 92.05 88.14 100 82.46 80.77 100 100 80.65 100 100 100 100 100 100 79.59 100 80.43 100 82.81 100 100 90.59 100 93.24 83.61 100 100 87.72 88.89 100 88.89 92.19 100 86.3 87.5 89.36 100 100 100 93.5 100 90 87.88 93.15 88.18 100 91.89 85.71 86.57 100 87.14 90.16 100 100 100 87.14 84.62 100 100 100 100 83.08 100 100 100 100 100 100 100 100 90.36 100 90.7 100 100 100 89.36 100 100 91.94 100 81.25 100 100 90.74 94.12 87.95 82.76 100 90.91 91.07 86.54 74.19 100 100 92.86 87.3 100 86.11 100 83.78 -16.22 0.000533 0.014939 K alternative_acceptor CDC45L chr22 + chr22:19504169-19504339 chr22:19504169-19504336 chr22:19504337-19504339 chr22:19504339-19504340 0 0 0 0 0 7.69 2.86 21.05 0 NA 0 NA NA NA 0 NA 11.11 NA 0 0 0 0 NA 0 NA 0 16.67 6.67 0 NA 0 0 9.52 18.75 0 14.29 0 7.69 0 0 0 0 NA NA 0 0 0 5.26 0 NA 9.68 4.08 0 0 NA 13.64 0 0 0 0 NA 0 10.53 0 0 0 0 0 0 18.18 0 0 0 6.25 NA 0 0 5 NA 0 NA 7.69 0 0 8.22 NA 0 0 0 0 NA 11.11 11.11 0 0 NA 0 6.85 2.9 5.88 0 0 5.36 0 0 0 3.85 0 0 0 NA 0 0 7.41 0 0 0 0 0 0 0 4.35 9.09 0 0 17.07 NA NA 0 NA 6.06 NA 0 NA NA 0 9.52 NA 0 NA NA 7.14 0 0 0 NA 0 NA 0 0 0 NA 7.14 7.94 NA 18.52 0 0 0 11.11 8.7 NA 0 13.33 10 0 5.71 0 2.82 0 0 0 0 11.11 11.11 0.001153 0.047498 N alternative_acceptor CDV3 chr3 + chr3:133305567-133306002;chr3:133305567-133307196;chr3:133305567-133306005 chr3:133305567-133306739 chr3:133306003-133306005;chr3:133306006-133306739;chr3:133306740-133307196 chr3:133306005-133306006;chr3:133306739-133306740;chr3:133307196-133307197 13.86 33.17 29.24 44.93 31.19 39.77 63.27 35.9 29.57 26.17 26.5 37.33 40.74 30.36 24.47 28.25 40 33.53 36.81 30.91 33.64 24.51 37.5 40.74 32.99 35.16 24.82 43.28 23.13 25.65 33.75 34.08 16.28 55.12 34.91 20 31.83 37.67 33.43 20.16 36.5 21.98 25.73 34.93 29.41 21.63 44.86 34.29 24.91 29.39 27.54 33.33 31.82 34.99 27.37 30.99 47.63 33.59 38.23 39.36 31.9 28.97 35.92 33.44 36.04 40.1 34.15 36.05 34 23.4 40 33.78 32.38 38.46 36.22 33.33 35.88 43.01 33.7 51.11 30.67 23.28 23.55 42.96 37.55 26.92 48.51 37.33 50.75 42.66 32.61 22.18 29.84 35.69 34.29 36.65 29.09 32.56 33.88 43.15 37.14 39.83 31.85 39.18 33.13 37.87 34.32 41.12 45.43 39.62 31.89 44.74 27.8 44.15 31.22 28.94 17.19 33.73 39.33 33.7 31.44 37.29 26.38 38.54 31.85 42.11 24.58 36.57 37.92 25 33.02 38.27 39.31 29.13 40 38.86 31.79 28.74 51.47 28.12 30.65 37.44 26.05 38.22 40.77 34.23 30.97 28.79 24.18 35.02 36.08 31.5 45.85 32.13 41.48 32.88 35.27 32.42 32.42 13.67 35.08 28.82 27.35 27.64 42.18 34.63 34.44 32.58 29.72 31.39 36.27 22.71 33.75 21.17 -12.58 0.000749 0.034087 K alternative_acceptor CELSR3,SLC26A6 chr3 - chr3:48670518-48670683 chr3:48670559-48670683 chr3:48670518-48670558 chr3:48670517-48670518 NA 0 NA NA 18.75 NA 11.29 NA 11.63 NA 0 NA 12.5 6.9 0 0 0 NA 3.85 9.09 6.67 16.67 8 5.26 0 0 10.42 5.36 11.69 13.16 3.92 NA NA 29.41 11.76 12 0 16.67 17.86 27.27 20 16.67 0 0 20.41 8.11 5.26 0 11.76 4.76 18.18 25 7.14 17.65 4.35 8.7 NA 0 10 8.11 12 19.05 6.52 10 13.16 13.64 0 0 23.08 21.88 19.05 0 0 0 8.06 11.11 NA 0 9.09 7.14 NA 19.61 3.85 11.76 6.9 NA NA 0 0 5 0 27.27 0 NA 18.84 5.56 9.09 8.11 5.26 0 4.26 8.43 10.96 4.65 NA 0 6 0 6.52 0 7.95 5.56 11.11 0 NA 9.09 17.39 9.09 0 13.64 16.67 7.14 4.84 3.45 0 12.07 9.09 NA 8.89 0 0 NA NA NA NA 0 22.73 0 0 3.7 0 0 4 NA 0 14.55 0 10 NA 0 0 0 5.41 9.09 0 10.71 0 16.67 0 20.83 21.74 0 11.76 0 NA 6.25 5.56 12 NA 6.38 6.25 0 6.52 23.44 16.92 0.000147 0.011285 N alternative_acceptor CENPO chr2 + chr2:25037363-25038466 chr2:25037363-25038365 chr2:25038366-25038466 chr2:25038466-25038467 NA 100 80 76.32 100 60 53.85 100 100 100 100 NA 100 100 100 NA 100 100 100 100 100 100 100 86.84 100 100 100 76.67 100 100 100 100 100 100 85.71 71.43 100 100 100 74.29 NA 100 100 100 70.59 81.25 100 100 100 100 100 80.77 72.73 100 NA 100 NA 100 100 85.37 100 82.14 100 100 80.77 100 100 100 100 75.76 100 100 100 100 100 100 100 100 100 100 NA 100 75 100 100 100 100 100 100 89.83 100 100 100 100 100 NA 83.33 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 77.42 100 100 100 100 100 100 79.41 80.65 100 81.25 79.17 NA 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 NA 100 NA NA 100 80 100 100 100 100 84.21 79.49 100 100 100 100 78.26 100 100 100 100 100 100 100 100 77.62 -22.38 0.000012 0.001214 N cassette CEP110 chr9 + chr9:123852684-123858699 chr9:123852684-123857165;chr9:123857297-123858699 chr9:123857166-123857296 100 85.53 92.17 100 89.39 NA 100 100 100 100 100 100 100 100 100 77.5 100 100 91.07 100 100 100 85.22 100 100 100 100 100 100 85.71 77.08 100 100 100 100 77.14 100 89.47 100 100 100 100 100 100 100 61.54 100 84.44 100 81.82 72.83 77.78 100 85.42 100 100 100 100 100 100 100 79.12 100 89.66 100 100 80 80.52 100 69.81 86.67 100 81.48 100 100 100 92.86 83.33 100 100 100 100 100 77.14 100 100 100 100 100 71.88 100 73.74 100 86.11 100 100 90.48 100 90.74 100 100 100 100 100 85.96 85 89.66 87.72 100 100 100 100 87.74 100 100 92.23 87.72 100 100 85.92 71.43 91.86 100 100 79.1 100 100 100 100 84.21 100 100 100 90.62 100 100 84.44 100 100 100 100 100 100 100 100 88.89 100 100 NA 100 NA 100 100 79.25 100 89.86 100 80.77 100 65.91 82.46 100 80.82 100 100 100 100 82.22 79.25 100 100 72 100 75.44 -24.56 0.000233 0.009161 N alternative_donor CEP170 chr1 - chr1:243289437-243289914 chr1:243289437-243289679 chr1:243289680-243289914 chr1:243289914-243289915 100 100 98.14 100 100 100 100 100 92 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.89 100 100 100 100 100 100 100 100 100 92.86 93.83 89.09 100 100 100 100 100 100 100 91.67 100 100 89.09 92.66 92.98 100 100 100 100 83.49 100 93.51 95.97 100 94.19 100 100 100 100 89.83 100 100 100 100 100 100 100 100 100 100 100 90.91 100 100 100 100 100 100 100 100 96.03 100 100 100 95.1 100 100 100 100 100 100 100 100 100 100 100 100 91.14 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 86.49 95.33 100 100 95.33 100 100 100 100 100 100 100 100 100 88.99 -11.01 0 0.000065 K intron_retention CEP170 chr1 - chr1:243289437-243289914 chr1:243289436-243289437;chr1:243289914-243289915 100 100 97.65 100 100 100 100 100 89.66 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 85.96 100 100 100 100 100 100 100 100 100 90 93.33 88 100 100 100 100 100 100 100 90.91 100 100 86.67 90.36 91.01 100 100 100 100 78.57 100 92.31 94.44 100 92.96 100 100 100 100 87.23 100 100 100 100 100 100 100 100 100 100 100 91.89 100 100 100 100 100 100 100 100 94.44 100 100 100 92.42 100 100 100 100 100 100 100 100 100 100 100 100 88.33 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 82.76 94.12 100 100 93.83 100 100 100 100 100 100 100 100 100 86.98 -13.02 0 0.001058 K alternative_acceptor CEP170 chr1 - chr1:243319650-243327585 chr1:243319758-243327585 chr1:243319650-243319757 chr1:243319649-243319650 100 85.71 80.6 73.17 79.63 NA 72.22 100 92.31 100 81.25 100 84.09 90.8 80 79.12 88.31 74.24 80.43 100 90.91 100 75 73.44 100 100 74.42 100 84.75 85.71 89.53 83.51 100 83.33 78.95 51.35 86.96 80 88.61 52.31 86.54 93.62 89.23 91.03 100 81.48 100 82.93 79.59 82.67 83.84 71.43 81.58 85.94 70.31 100 100 79.45 83.33 74.38 83.82 83.58 91.03 87.9 73.08 79.41 87.64 80 85.48 41.67 88.17 89 83.73 85.87 86.57 86.9 84.31 87.85 82.56 78.69 90 75.38 85 100 79.82 100 100 90.91 72.54 87.8 100 68.89 100 77.57 85.88 85.56 100 73.85 78.72 81.97 71.43 82.89 81.63 89.29 78.08 82.67 74.77 88.64 86.11 100 79.55 89.47 81.44 77.78 78.38 81.4 80 90.62 79.59 93.58 84.13 76.92 74.07 84.27 84.42 100 87.84 89.74 100 86.17 82.5 100 100 100 100 100 100 100 100 100 100 81.91 100 76 78.31 80.7 100 89.16 100 100 NA 100 84.93 80.49 85.11 76.47 90.7 80.26 68.75 50 82.44 100 83.48 86.09 59.09 100 88.6 84.11 85.51 87.85 93.24 89.52 85.71 51.83 -33.88 0.000036 0.003443 K cassette CEP192 chr18 + chr18:13069856-13072753 chr18:13069856-13071037;chr18:13071212-13072753 chr18:13071038-13071211 100 100 91.01 82.14 100 100 72 100 100 100 100 100 100 83.75 100 100 100 100 85.71 100 100 100 100 100 100 100 86.15 100 100 100 100 100 100 100 100 100 100 100 100 70.83 100 100 100 100 100 89.23 100 100 100 100 100 80 100 100 100 100 100 100 100 100 100 100 100 100 88.75 100 100 100 100 87.1 100 100 100 100 100 100 100 100 100 100 100 100 85.37 100 100 100 100 100 100 100 100 100 90 100 100 100 90 89.66 100 100 100 100 100 100 85.71 83.33 100 100 100 100 100 89.13 88.89 100 100 100 100 100 100 100 88.24 88.06 87.32 100 100 100 100 100 92.19 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 90.91 77.42 85.96 100 100 87.5 85.11 100 100 100 100 65.85 100 100 100 92.42 87.5 87.5 85.71 100 86.1 -13.9 0.000645 0.016961 K alternative_acceptor CHCHD7 chr8 + chr8:57127227-57128991 chr8:57127227-57128947 chr8:57128948-57128991 chr8:57128991-57128992 21.05 50 23.73 31.58 39.39 21.21 10 16.22 22.22 29.41 25.71 0 29.17 29.03 42.03 16.13 16.95 17.39 24.68 38.46 28.57 45 50 29.55 26.53 36.27 38.46 26.87 23.53 26.09 27.59 7.69 0 16 18.84 10.71 16.95 19.18 32 8 10 38.1 18.37 28.57 20.73 NA 32 34.69 37.14 23.26 32.08 15.7 31.82 20.78 43.48 34.55 10.64 32.5 33.33 26.92 30.3 24.14 30.23 42.86 32.14 26.32 28.26 20 24.39 14.52 16.88 0 29.09 27.69 23.44 38.46 26.32 20.34 20.69 26.88 36.36 29.73 22.73 22.86 23.81 NA 33.87 20.59 30 21.66 0 4 27.27 NA 25 22.86 57.38 40.4 48.89 35.44 25.48 25 31.78 22.02 21.97 20.59 22.22 21.05 23.75 23.4 30 28.92 27.03 12.5 37.5 25.23 52.94 23.91 0 23.08 22.58 25.68 43.28 17.46 34 21.05 9.52 35.71 21.43 21.43 28.89 23.81 30.23 0 20.93 26.09 18.6 21.21 32.14 19.35 18.18 20 42.2 32.43 20 29.23 31.43 10 23.26 12.9 0 15.49 26.58 18.37 22.22 37.04 22.86 19.05 46.67 2.99 32.31 25.32 28.57 15.79 28.46 23.53 28.33 42.86 28.57 0 6.25 27.27 25.7 9.36 -16.34 0.000466 0.026365 K cassette CHEK2 chr22 - chr22:29095926-29105993 chr22:29095926-29099492;chr22:29099555-29105993 chr22:29099493-29099554 100 100 100 80.77 86.44 NA 100 100 100 100 100 NA 100 100 85.51 100 100 100 100 100 NA 100 74.29 100 82.86 100 81.25 100 100 100 100 100 100 NA 100 NA 82.76 82.93 78.38 66.67 NA 100 NA 100 73.81 100 69.57 100 100 100 87.5 79.41 100 91.3 100 100 100 100 100 100 100 75 100 72.22 100 100 100 100 100 70.83 100 NA 79.41 100 100 78.57 NA 76 100 100 100 100 72 77.27 100 100 100 100 100 100 NA 74.36 78.26 100 100 NA 100 68.57 84.85 68.75 100 100 83.33 100 81.82 100 100 100 80.77 100 100 83.33 67.74 100 100 100 100 100 NA 79.17 100 100 76.47 67.5 84.21 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 72.92 100 100 100 100 57.14 100 NA 100 100 100 100 78.95 100 NA 100 NA 80.56 68.42 57.69 100 100 NA 100 100 100 100 100 100 62.5 100 100 70.83 -29.17 0.000047 0.002704 N cassette CHPF2 chr7 + chr7:150932715-150934459;chr7:150932699-150934459 chr7:150932699-150933493,chr7:150932715-150933493;chr7:150933677-150934459 chr7:150933494-150933676 84.72 100 88.14 73.49 82.69 69.09 43.45 100 78.21 88.89 91.25 100 100 93.9 100 73.85 78.05 82.43 91.41 100 94.05 100 100 86.84 87.34 81.71 100 87.3 93.27 100 86.84 78.87 100 100 100 73.21 88.33 83.17 88.42 66.67 78.69 87.5 100 89.02 84.62 81.58 88.3 84 90.91 88.5 85.27 78.87 83.19 92.59 83.81 84.07 100 90.8 94.06 85.58 100 83.08 85.92 86.67 87.18 89.89 92.52 88.1 89.02 68.92 87.62 100 85.51 85.71 83.33 85.11 74.58 100 93.33 72.62 80.22 100 80 86.42 100 100 100 80 83.13 100 100 69.7 100 100 78.12 100 100 86.27 92.81 87.4 86.67 82.52 90.71 86.36 100 100 86.44 88.19 83.44 78.43 88.89 87 88.54 85.94 90.48 100 100 76.79 100 100 100 85.59 88.11 83.05 100 90.8 86.84 100 85.57 80.56 88.89 100 100 100 100 100 90.14 72.31 100 100 91.4 100 100 85.24 89.66 100 85.92 100 82.35 100 100 100 89.25 78.63 75.81 100 90.8 80.17 77 76.19 92.16 85.05 93.75 85.96 74.16 82.26 100 100 89.58 75 77.78 87.76 88.89 71.45 -17.44 0.000098 0.004785 K cassette CHRAC1 chr8 + chr8:141521746-141525224 chr8:141521746-141524467;chr8:141524595-141525224 chr8:141524468-141524594 100 100 100 93.02 100 100 100 100 100 100 100 100 87.5 100 100 100 91.35 94.33 93.83 100 100 100 100 100 100 100 92.45 93.08 100 100 90.23 100 100 91.57 100 90.74 100 93.68 100 85.25 100 100 100 100 100 93.15 85.92 92.78 100 100 100 86.87 100 94.74 94.68 91.8 100 100 100 93.83 100 100 100 87.5 93.33 100 100 100 94.12 92 93.33 92.75 90.14 100 100 100 100 88.89 100 100 100 100 100 100 95.14 100 90.52 93.88 92.59 94.85 100 92.24 100 100 90.59 100 91.07 88.82 100 91.8 92.93 100 92.31 100 92.71 100 100 100 100 100 100 91.74 100 100 90 93.15 89.71 95.15 100 100 100 94.23 100 94.81 100 93.5 91.38 100 93.46 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.55 88.31 100 100 100 100 100 100 100 93.14 100 89.71 100 88.71 100 88.57 81.08 100 100 100 100 100 100 93.1 92.11 100 87.5 100 86.89 100 88.81 -11.19 0.000032 0.001917 K alternative_last_exon CHURC1 chr14 + chr14:65392799-65397517,chr14:65392799-65407196;chr14:65392799-65410016;chr14:65392799-65470966 chr14:65392799-65398855 chr14:65410017-65411309;chr14:65470967-65471031 chr14:65398856-65401913 93.02 93.89 92.92 86.44 92.68 88.24 61.11 89 85.29 97.1 91.09 95.93 86.57 90.91 94.87 89.53 86.11 93.75 89.29 88.46 94.07 92.75 91.59 82.93 96.67 93.6 86.73 89.39 93.58 79.44 91.67 89.26 85.71 91.38 95.71 75 87.5 93.1 94.06 78.95 91.11 91.11 91.87 96.81 89.47 71.25 96.74 93.26 91.84 93.53 96.67 65.96 79.55 96.55 86.67 79.63 91.51 92.31 95.24 95.54 92.97 87.72 88.16 86.96 91.25 91.75 85.87 86.36 94.35 90 87.21 93.33 93.85 87 95.88 92.39 83.53 72.55 96.03 89.69 93.33 88.31 87.32 89.09 96.4 83.72 89.23 91.36 95.9 87.61 87.27 69.44 89.13 90.7 82.83 86.67 96.95 93.85 88.07 85.71 94.44 82 84.48 79.01 93.46 89.69 94.37 96.81 79.31 80.65 91.3 90.12 91.22 89.19 85.71 90.7 83.82 97.44 89.86 93.97 96.83 97.99 94.41 92.89 88.06 94.74 93.94 85.71 82.14 83.33 96.49 93.81 85.45 93.33 86.89 92.37 92.81 92.45 90.28 86.49 94.92 91.95 96.61 94.85 88.24 90.48 91.67 87.1 94.44 87.1 97.2 83.33 93.7 95.5 84.62 89.04 79.35 95.12 80.52 76.98 86.11 90.72 92.91 87.3 82.14 96.55 87.78 84.29 90 94.38 78.33 89.86 90.91 75.99 -14.92 0.00064 0.048555 N alternative_acceptor CKAP5 chr11 - chr11:46842800-46867770 chr11:46842820-46867770 chr11:46842800-46842819 chr11:46842799-46842800 100 100 100 73.33 100 NA NA 100 100 100 80 NA NA 100 100 100 100 100 100 100 NA 100 100 100 NA 100 100 100 100 NA 100 100 100 NA 100 52.63 100 100 100 68.18 NA 100 NA NA NA 100 NA 100 100 75 100 100 NA 100 100 100 100 100 100 100 NA 100 53.85 100 66.67 NA 100 NA 100 58.33 100 100 100 100 NA NA NA 100 100 100 NA 100 100 NA 100 NA 60.47 NA NA 100 100 75.38 100 100 NA 100 100 100 NA NA NA NA NA NA 100 NA 78.26 100 NA 100 NA 100 100 100 100 68.75 100 100 NA 67.86 100 NA NA NA 100 NA NA 100 100 100 82.86 100 100 100 54.17 100 100 NA 100 NA NA 100 100 100 100 60 NA 100 NA NA NA NA NA 100 100 78.26 100 NA 100 72.73 68.75 100 100 100 100 NA 83.33 100 100 NA NA 64.29 100 70.46 -29.54 0.000007 0.000716 N cassette CLR chr12 + chr12:9808576-9809516;chr12:9808686-9809516 chr12:9808576-9809163,chr12:9808686-9809163;chr12:9809294-9809516 chr12:9809164-9809293 11.59 49.58 NA 29.07 59.26 23.53 33.33 18.52 39.13 22.81 22.41 NA 50 40.7 NA 28.12 15.12 NA 32.65 48.28 40.38 21.05 40.74 17.74 47.06 10.91 23.26 35.29 27.03 28.57 11.76 13.51 32.76 28.81 65.31 14.81 20.51 46.15 57.14 2.7 27.27 15.62 18.75 25 40.91 55 22 18.64 NA 10.2 53.57 10.71 36.84 26.09 29.17 20.9 6.82 13.16 61.4 24.39 48.08 15.15 19.51 11.11 27.27 19.35 16.67 NA 31.82 24.44 28.33 12.2 NA 45.71 35.87 46.51 18.57 NA 44.44 40.62 37.04 30.77 39.29 10.26 25 21.74 17.24 20.83 26.67 18.75 24.24 20.83 25 21.74 12 32.08 33.33 36.73 15.79 35.48 20.41 20.88 29.55 23.08 22.64 8.33 51.35 21.15 38.46 18.75 20 30 17.95 NA 26.83 16.28 45 NA 15.38 24.11 16.95 25 32.58 19.35 NA NA 54.55 50 18.57 33.33 15.56 16.13 17.24 21.05 NA 29.31 16.85 50 23.81 36 25.58 25 51.28 21.74 21.21 21.35 28.21 25.42 55.56 47.22 NA 16.44 31.25 42.86 12 42.86 22.5 21.88 24.71 6.25 52.5 13.95 32 44.19 28.57 41.18 13.33 24.56 22.22 43.48 21.05 24.24 25.21 12.76 -12.45 0.002723 0.048824 N cassette CNOT10 chr3 + chr3:32804356-32806173 chr3:32804356-32805946;chr3:32805983-32806173 chr3:32805947-32805982 100 100 88.89 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 77.78 100 100 100 80 100 100 100 100 75.86 100 100 89.13 84.91 100 100 100 100 100 67.86 100 89.8 100 100 100 86.11 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.1 100 100 88.46 100 100 85.71 100 100 100 100 100 100 90.38 100 100 100 100 100 100 100 100 89.8 91.67 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.89 91.38 100 100 100 88.1 100 100 100 100 83.78 100 100 100 100 100 100 100 100 100 75 100 81.4 100 100 100 100 100 100 100 100 100 100 100 100 100 100 91.23 100 100 100 100 100 100 100 100 100 100 100 100 100 100 81.82 100 100 100 89.36 100 100 100 100 100 90 100 100 100 100 87.28 -12.72 0.000151 0.006663 K alternative_acceptor COPS2 chr15 - chr15:49429635-49431724 chr15:49429656-49431724 chr15:49429635-49429655 chr15:49429634-49429635 17.07 19.13 22 16.09 20 33.33 17.91 27.41 34.69 30 26.88 NA 34.21 21.31 23.02 27.27 28.21 22.78 38.1 28.95 18.64 18.75 33.33 27.59 21.31 32.08 27.78 22.12 33.9 23.26 29.31 31.67 100 22.22 30.13 13.64 24.64 23.64 30 9.09 25 18.52 22.95 20.16 12.5 18.18 31.43 35 20 28.99 30.26 10 21.21 18.33 26.09 25.71 25.42 27.03 34.15 32.5 22.39 13.33 27.27 19.67 20 26.42 35 20.41 22.95 17.81 22.64 26.92 24.53 17.54 20 20.97 15.56 27.91 21.95 23.68 23.81 27.03 25 25.76 19.23 25 23.08 20 30.16 30.51 23.33 16.46 30.43 26.39 27.42 52.63 18.75 31.91 35.14 23.08 22.54 25 21.15 44.44 20.97 24.64 21.43 21.88 20.93 27.08 24.44 25.35 25.88 16.28 24.73 25.93 23.64 33.86 37.74 21.21 29.17 23.53 24.29 23.33 19.51 20 35.48 17.02 23.88 16.39 22.98 31.43 31.58 25.37 30.43 8.77 35.29 21.43 27.27 35.71 11.11 21.05 22.92 23.08 14.16 23.53 21.74 23.08 40 20 32 24.07 28.33 27.27 26.67 25 31.03 20.69 28.3 10 16.07 22.22 28 21.43 13.22 33.33 25.71 25 24.64 15.38 27.27 29.79 24.59 11.82 -12.77 0.000112 0.008756 K alternative_acceptor CPSF3L chr1 - chr1:1254814-1255835 chr1:1254905-1255835 chr1:1254814-1254904 chr1:1254813-1254814 100 100 100 100 100 100 91.06 89.23 95 100 87.72 100 89.29 100 100 100 84.78 84.62 91.96 100 89.89 100 100 94.89 93.58 100 100 94.07 100 94.51 94.74 100 100 91.98 100 83.58 100 95.56 92.86 80.17 100 100 93.14 100 100 100 100 100 95.05 93.94 100 81.82 100 100 91.95 100 100 93.9 100 91.84 100 100 88.75 92.31 93.28 92.21 93.62 100 95 89.13 88.3 95.41 92.5 91.38 94.25 94.23 90 100 100 94.78 78.67 94.25 100 100 94.12 100 100 96.45 92.5 95.31 100 89.36 100 100 100 100 100 100 92.57 95.33 95.15 88.18 89.86 89.91 100 93.69 95.89 97.08 94.39 100 95.35 94.23 100 100 100 94.44 100 95.15 100 94.74 100 91.84 91.23 100 100 96.41 100 100 93.75 100 100 100 100 100 100 100 100 100 93.64 100 100 100 100 91.63 100 100 100 100 100 100 100 100 93.91 100 92.22 87.8 100 90.91 91.82 87.06 100 100 91.06 91.18 100 92.31 92.93 100 93.6 100 84.29 89.66 100 85.32 -14.68 0.000019 0.001867 N cassette CR592318 chr10 - chr10:81565879-81574368;chr10:81564284-81574368 chr10:81565879-81568514,chr10:81564284-81568514;chr10:81568589-81574368 chr10:81568515-81568588 67.02 44.55 42.72 39.78 72.06 51.72 81.01 62.12 53.85 45.92 52.05 100 39.71 52.34 48.31 22.86 48.19 40.71 60 43.33 50 56.45 31.94 46.43 45 100 64.58 50.59 58.93 33.33 42.4 40.21 56.67 47.97 60.92 31.43 47.06 42.48 40.62 41.98 58.54 51.47 43.75 64.89 56.25 32.43 55.93 57.58 46.32 53.66 47.1 38.75 40.74 45.51 26.67 42.42 50.62 51.52 45.1 41.75 76.04 72.15 61.9 49.3 40.37 64.15 64.75 49.18 41.6 36.27 47.62 40 48.94 47.32 44.66 41.18 40 52.78 46.67 57.75 67.09 46.75 51.02 68.29 49.53 52.63 35.79 62 44.95 46.97 51 35.64 31.91 30 70 73.81 29.59 40 35.96 49.7 43.45 25 56.14 55 54.55 48.36 46.4 42.62 33.68 100 50.89 46.34 33.53 39.16 32.76 50 29.17 0 47.31 41.6 46.6 37.33 56.12 49.62 70.97 43.69 49.18 43.01 40.2 37.36 60.94 56.83 67.44 38.4 52 44.09 49.48 58.21 53.27 65.75 48.28 60 42.31 35.37 61.62 42.53 63.64 46.34 34.42 43.04 60.92 50.77 49.57 69.91 44.16 72.22 74.36 44.29 55.26 40.45 55 65.56 38.1 56.45 45.71 47.46 46.43 48.65 35.58 42.47 53.12 66.07 48.31 37.51 -10.8 0.002806 0.04998 K cassette CRCP chr7 + chr7:65592728-65599266 chr7:65592728-65595730;chr7:65595830-65599266 chr7:65595731-65595829 100 100 88.24 100 100 94.12 73.81 100 82.43 100 91.43 100 100 88.24 100 84.44 90.62 91.07 90.74 100 100 100 100 100 100 87.3 100 94.05 100 91.18 100 100 100 100 100 82.61 100 92.47 87.5 85.53 91.8 100 89.16 96.23 84.78 85.9 88.64 100 89.39 94.12 92.05 100 86 100 94.55 95 100 88.57 100 89.02 100 100 100 90 93.59 90.2 92.19 87.5 93.15 88 89.19 87.8 96 91.55 100 92.05 100 100 100 87.3 100 100 88.71 100 100 100 86.54 100 88.41 90.32 100 79.37 93.02 100 95.38 100 91.94 100 87.5 100 91.76 100 89.41 100 100 87.18 91.53 83.93 90.16 100 89.47 91.67 92.86 100 87.01 100 100 86.36 100 90.59 100 91.03 100 100 93.51 100 92.06 100 89.66 100 91.14 100 81.43 100 100 81.43 100 100 100 87.23 100 100 100 90.54 100 91.78 100 100 100 100 100 100 89.71 86.21 91.07 100 100 93.33 92 81.33 89.47 100 89.02 86.15 100 100 95.31 94.74 92.16 100 92.31 85.96 100 84.07 -15.93 0.002747 0.049178 N alternative_acceptor CRYZL1 chr21 - chr21:34971592-34974539;chr21:34973641-34974539 chr21:34971555-34974539 chr21:34971555-34971591;chr21:34971592-34973640 chr21:34971554-34971555;chr21:34971591-34971592 72.73 55.74 68.42 48.15 69.09 69.7 82.14 90 65.52 76.92 87.5 NA 83.02 70.27 76 66.67 70 71.58 76.12 97.44 78.38 60 67.39 80.88 84 68.18 54.17 85.45 72 70.37 89.47 78.87 88.68 78.26 82.76 89.19 61.9 67.53 73.21 83.87 71.43 NA 68.42 69.12 80.65 47.37 92.65 86.36 86.36 76.12 76.74 92.65 63.41 89.66 64.1 58.14 95 68.85 62 73.08 72.22 62.16 84.78 71.21 82.46 69.09 65.67 71.7 78.87 83.51 73.85 75 66.1 70.67 78.57 70.21 81.03 85.11 72.92 71.93 83.33 60.38 63.33 83.67 73.47 45.1 82.14 75 77.36 78.26 71.43 83.87 49.06 84.44 68.75 62.07 50 72.31 70.33 65.71 79.17 71.67 90.7 77.5 78.81 73.33 58.21 77.78 79.07 44 62.5 84.62 45.1 58.82 80.39 66.2 70.51 78.57 75 66.67 76.47 78.67 44.44 75.58 71.43 68 79.41 76 78.85 61.54 80.95 83.87 75 60.71 68.75 86.89 79.07 67.5 47.37 85.71 54 88.68 90.91 73.08 69.23 76.32 66.67 65.31 82.61 90.57 NA 54.55 69.23 58.46 77.55 73.21 55.56 68.25 64.29 92.19 64 65.57 67.47 74.29 71.74 75 64.29 76.56 75 66 71.43 78.43 72.52 86.53 14.01 0.000635 0.029995 N alternative_acceptor CTNNB1 chr3 + chr3:41280846-41281312;chr3:41280846-41281309 chr3:41280846-41281150 chr3:41281151-41281309;chr3:41281310-41281312 chr3:41281309-41281310;chr3:41281312-41281313 88.63 74.67 81.99 85.22 71.6 98.99 86.72 81.43 74.65 71.43 68.89 98.85 80.7 69.93 66.85 74.07 78.38 89.43 79.46 65.22 76.47 60.32 85.06 81.25 85.51 64.02 65.83 80.77 86.57 71.01 84.44 78.95 NA 77.32 75.21 96.77 86.67 88 83.19 98.46 90.91 77.03 81.36 64.62 62.38 72.31 84.4 78.12 84.71 88.71 75 92.77 97.56 83.12 90 81.67 78.23 70.69 74.67 80.25 87.23 73.08 82.18 85.42 79.13 89.71 86.05 83.87 83.67 90.32 83.33 71.05 84.62 82.11 86.73 85 93.9 79.21 80.39 83.53 90.24 75.61 82.69 88.89 79.23 79.08 83.93 95.65 87.88 73.14 NA 99.01 77.5 81.82 74.42 94 72.07 69.14 76.53 77.78 68.24 83.7 75.63 86.21 88.51 73.38 68.57 68.59 76.19 72.06 74.51 67 88.73 NA 58.26 81.51 87.3 74.23 98.59 88.24 87.62 87.18 83.7 90.35 87.5 75.68 84.44 71.43 77.04 81.82 69.64 96.23 62.77 98.57 68.75 83.33 74.53 73.5 96.15 95.95 77.78 77.46 98.67 78.82 72 85.34 82 76.56 71.43 65.38 96.92 62.3 73.53 85.62 98.68 98.21 74.7 90.48 98.28 98.59 87.3 88.36 84.06 90.57 75.79 82.42 76.36 89.55 83.05 77.19 82.42 98.68 81.67 97.61 15.94 0.000303 0.020313 N cassette CTSC chr11 - chr11:88045723-88068104;chr11:88059612-88068104 chr11:88045723-88061279,chr11:88059612-88061279;chr11:88061365-88068104 chr11:88061280-88061364 41.57 20.09 20.68 25.81 32.26 42.62 34.55 30.77 18.65 42.48 18.63 53.49 26.83 24.38 39.1 20.62 33.48 32.67 30.12 22.6 18.41 26.53 21.45 22.31 35.14 30.38 32.19 20.83 22.83 19.5 23.4 20.96 54.16 19.85 18.3 9.58 32.57 30.84 27.46 6.44 17.82 24.66 21.07 21.15 37.86 19.44 25.52 26.14 26.13 21.65 27.11 14.83 35.67 23.1 30.54 26.69 28.43 35.44 22.86 20.55 22.81 35.48 22.49 25.85 23.54 29.72 31.32 25 26.67 8.02 24.84 12.23 25.6 27.85 20.69 23.66 28.57 25.52 25.06 25.57 37.8 31.33 36.97 20.13 39.27 32.58 30.48 30.98 23.45 25.6 19.59 11.52 19.78 16.81 23 16.01 30.77 10.68 25 21.35 27.73 14.03 31.62 30.5 23.39 23.72 24.33 22.48 24.66 31.25 18.86 23.99 26.9 39.47 25.26 19.38 24.6 24.43 27.04 29.76 13.69 21.22 25.44 29.05 38.72 17.84 18.48 25 27.12 24.14 29.08 20.89 27.12 29.9 21.74 26.44 22.17 20.45 23.16 18.13 24.81 25 44.9 15.15 29.58 17.13 38.24 20.23 55.46 35.79 32.2 34.51 23.99 43.7 27.03 22.87 23.19 28.85 20.75 8.24 33.29 38.41 30.06 35.36 25 35.76 20.67 28.54 28.38 22.71 23.42 33.86 25.52 8.91 -16.61 0.00004 0.002346 K alternative_acceptor CWF19L1 chr10 - chr10:102020786-102021735 chr10:102020802-102021735 chr10:102020786-102020801 chr10:102020785-102020786 NA 53.57 100 50 100 NA 61.9 100 100 100 65.38 NA 100 72.22 100 57.89 55.26 100 75 100 75.76 NA 51.28 75 100 100 57.14 79.17 100 80 63.33 70 NA 100 60.87 58.82 71.88 70 100 50 66.67 61.9 70.37 100 NA 100 75 77.5 70.83 55 76.32 NA 63.16 100 68.75 66.67 100 66.67 100 57.14 55.56 38.89 71.43 70.83 71.43 43.48 64.71 100 67.74 48.48 70.83 70 60 62.5 53.33 78.79 50 100 65 70.37 66.67 70.83 72.22 69.23 52.78 NA NA 55.17 72.73 78.26 NA 35 100 NA 68.75 100 100 59.09 100 70 71.43 64.29 100 55.56 69.57 62.5 100 100 60 100 69.57 72.41 71.43 NA 100 65.38 48.15 NA 100 50 57.14 70.37 57.58 71.88 65 100 70 NA 83.87 42.11 100 73.47 100 100 NA 100 51.72 58.33 NA NA NA 100 NA 100 100 65.62 53.33 100 NA NA NA NA 100 NA 62.5 74.07 72.22 100 57.69 54.84 57.14 100 76 NA 68.18 61.54 78.12 100 58.82 57.14 NA 76.19 71.43 50 -21.43 0.000954 0.040869 K cassette DAP3 chr1 + chr1:155697530-155698998 chr1:155697530-155698832;chr1:155698914-155698998 chr1:155698833-155698913 100 90.38 95.98 100 100 100 95.68 100 94.79 100 95.68 100 100 100 95.74 100 100 100 93.94 100 100 100 100 100 94.68 100 100 94.51 90.28 94.79 94.5 100 100 100 100 86.32 95.03 95.4 100 84.5 91.46 94.44 100 100 100 85.26 100 89 96.07 95.21 90.29 91.35 100 100 93.16 100 100 86.11 96.27 100 100 100 94.12 100 91.8 100 100 100 93.79 86.26 95.27 93.48 100 100 92.46 95.27 100 100 100 100 100 100 91.74 93.87 95.45 91.74 89.33 93.13 100 93.63 100 91.87 100 100 100 100 100 92.17 100 87.5 100 95.54 96.35 100 100 93.65 100 100 100 100 100 100 100 100 88.64 90.99 89.53 100 100 95.29 92.86 100 91.95 100 95.56 100 100 100 95.97 100 96.6 100 92.05 100 100 94.71 100 90.11 100 100 89.6 100 100 94.27 100 94.01 100 100 100 100 100 100 100 95.42 100 100 100 92.22 93.21 86.16 91.34 100 94.21 100 93.91 95.68 96.62 100 100 100 100 95.93 100 86.29 -13.71 0.000022 0.001347 K cassette DCLRE1C chr10 - chr10:14977564-14981808 chr10:14977564-14978536;chr10:14978593-14981808 chr10:14978537-14978592 100 100 78.95 100 100 100 100 100 100 100 79.55 100 81.48 100 100 100 53.57 81.82 83.33 100 82.35 100 100 100 100 100 75 100 100 100 100 77.5 NA 100 100 73.91 100 80.7 100 51.85 100 87.18 88.64 100 100 64.86 100 83.33 100 100 81.82 71.43 73.68 100 100 100 100 100 100 83.87 100 100 100 81.58 100 100 77.78 76.74 100 46.97 100 80.77 77.55 100 100 86.49 80.77 100 83.33 100 75 100 80.77 100 100 83.33 100 100 100 100 100 100 100 100 100 100 100 80.43 85.71 100 100 100 87.5 100 100 82.76 100 100 86.49 100 100 100 100 NA 62.96 85.71 68.75 100 100 100 100 85.71 100 100 100 100 76 100 100 100 100 100 100 100 100 100 100 79.41 100 100 100 100 100 72.97 100 88.37 100 80 NA 100 NA 100 100 100 100 100 100 76.67 100 62.07 100 100 86.96 100 100 100 86.49 100 100 100 70.37 100 100 66.75 -33.25 0.000076 0.004032 N alternative_acceptor DDHD2 chr8 + chr8:38117666-38118081;chr8:38117666-38119055 chr8:38117666-38118117 chr8:38118082-38118117;chr8:38118118-38119055 chr8:38118117-38118118;chr8:38119055-38119056 97.37 97.06 88.17 98.21 98.36 96.67 100 97.78 96.43 96.77 97.56 NA 82.98 97.44 96.67 83.64 78.57 90.48 87.3 97.44 97.96 96.77 96.3 83.58 96.97 96.15 96.55 97.78 80.95 96.43 82.93 98.18 96.15 97.44 97.78 73.33 98.11 90.91 97.5 83.02 95.35 98.98 97.3 97.3 96.88 96.15 86.96 98.84 86.57 88.1 87.04 71.43 88.24 90.28 85.94 97.73 97.78 98.53 98.39 86.05 89.33 82.98 96.43 97.56 98.33 97.73 85.92 98.11 85.71 71.76 98.25 91.89 85.25 91.86 97.56 87.72 89.86 96.97 98.57 81.58 83.33 89.29 97.37 97.87 86.49 97.56 98.63 89.83 89.04 96 93.75 88 87.5 79.41 91.89 96.15 97.18 85.43 90.12 86.21 81.25 97.92 97.22 87.1 84.91 84.06 97.1 75.58 97.14 96.97 97.62 83.05 92.11 96.67 98.46 97.78 81.82 86.78 97.3 90.28 87.23 96.72 97.96 88.12 88.89 84.21 97.06 97.44 82.98 97.96 98.21 98.33 97.44 97.44 96.55 96.55 86.11 93.75 95.92 93.75 94.34 85.71 95.65 85.96 98.72 96.43 85.71 97.67 96.97 96 97.22 94.12 89.06 86.44 97.83 97.3 73.75 97.56 92.31 74.14 98.25 73.33 87.69 98.21 97.56 82.86 98.41 92.38 89.71 98.53 89.23 98.21 96.37 73.73 -22.63 0.000261 0.018316 N alternative_acceptor DDX11 chr12 + chr12:31227026-31231396 chr12:31227026-31231323 chr12:31231324-31231396 chr12:31231396-31231397 100 100 82.93 100 100 84.62 73.53 100 100 100 100 100 100 100 100 100 78.72 100 80 100 100 100 100 100 100 100 100 100 100 100 100 100 85.29 100 100 81.4 100 93.67 100 100 100 100 100 100 100 100 100 100 88.37 100 100 69.23 100 80.7 100 86.36 100 100 100 100 100 89.13 100 100 100 100 100 100 100 77.5 79.49 100 100 100 100 100 100 100 100 100 100 81.82 100 87.8 82.76 100 100 100 100 100 100 85.71 86.49 100 100 100 100 78.57 93.1 100 100 100 100 100 85.71 100 100 100 100 100 100 90.74 100 100 88.89 100 100 100 100 100 100 100 100 88.89 100 100 100 100 100 100 100 100 100 100 100 100 84.91 87.18 100 NA 100 100 100 100 89.36 100 100 100 100 100 100 100 100 91.67 100 82.61 100 100 100 68.29 92.75 100 100 100 84.62 100 100 100 91.04 100 100 100 100 79.45 -20.55 0.000007 0.000765 N alternative_acceptor DDX26B chrX + chrX:134680395-134680697 chrX:134680395-134680626 chrX:134680627-134680697 chrX:134680697-134680698 NA 100 100 100 100 NA 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 NA 100 100 100 NA 100 82.76 100 100 100 100 100 100 100 65.38 80 100 100 100 100 100 100 100 100 100 100 100 100 100 100 76.47 NA 100 100 80.77 100 100 80 100 100 100 100 100 100 NA 100 84.38 82.35 76.92 100 100 100 100 100 100 81.82 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 89.09 100 100 100 100 100 NA 100 100 100 88.06 100 100 100 100 90.74 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 75 100 100 100 100 100 100 100 NA NA NA NA 100 100 100 100 100 79.17 100 78.05 100 100 100 100 100 100 100 100 100 100 100 NA 100 77.48 -22.52 0.000001 0.000116 N cassette DDX50 chr10 + chr10:70679738-70694554 chr10:70679738-70693954;chr10:70694117-70694554 chr10:70693955-70694116 100 100 100 90.38 100 100 68.29 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.33 100 100 100 100 100 100 100 100 100 100 100 77.22 100 100 100 100 100 100 100 100 100 100 100 89.09 100 100 100 100 100 100 100 100 100 100 82.14 100 100 100 93.67 91.94 89.61 89.71 100 100 100 100 100 100 100 100 100 100 100 100 100 100 94.17 100 100 88.14 100 100 100 88.1 100 100 100 100 100 77.92 100 100 100 100 100 100 90.91 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 86.84 100 80.56 100 100 91.89 100 100 100 100 91.8 100 100 100 100 100 88.59 -11.41 0 0.000002 K cassette DENND4C chr9 + chr9:19369986-19372034 chr9:19369986-19371753;chr9:19371819-19372034 chr9:19371754-19371818 100 100 100 100 100 100 37.5 100 100 100 81.63 NA 100 100 100 100 100 77.97 81.82 NA 79.31 NA 100 100 NA 100 NA NA 73.68 100 100 100 100 100 100 64.29 100 80 75 66.67 100 85.19 100 100 100 75 100 100 100 85.71 66.67 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 67.86 75 76.19 80.56 100 100 100 100 100 74.19 100 100 72.73 100 100 100 100 84.21 100 100 100 67.74 NA NA NA 100 78.57 100 100 82.86 100 100 NA 100 100 NA 100 100 100 100 84.21 70.83 100 100 100 78.79 NA 100 80 78.95 100 70.37 100 77.27 100 61.76 74.07 100 100 100 100 100 100 100 100 100 100 NA NA 100 100 100 NA NA 100 NA 100 100 73.91 100 100 NA NA 100 100 NA 76.19 NA 100 100 100 100 65.22 67.74 100 100 100 57.14 NA 100 80.77 100 100 100 66.67 100 65.94 -34.06 0.000091 0.004564 K cassette DIAPH2 chrX + chrX:96013258-96136577 chrX:96013258-96018098;chrX:96018120-96136577 chrX:96018099-96018119 100 100 100 100 100 100 77.42 100 83.08 100 76.67 100 75 77.42 100 100 86.36 80.88 88.73 NA 79.63 62.79 80.3 100 100 100 71.11 87.14 87.8 77.78 88.64 83.33 100 100 82.35 100 84.78 100 100 59.09 79.17 86.05 84.91 100 100 100 NA 100 100 100 77.08 65.85 100 86.59 83.33 71.79 73.21 100 100 81.4 100 100 67.24 81.03 100 100 100 100 100 69.44 84.21 100 100 100 100 100 100 NA 78.38 100 85.42 79.17 100 78.26 86.21 100 100 100 100 59.26 100 64 100 100 84.78 80 60.61 100 88.89 85.29 100 80.77 71.43 100 85.71 NA 100 100 84 71.88 70 100 90.57 100 100 76.92 100 NA 100 100 100 100 73.53 75.76 80.49 100 85.71 100 86.15 100 100 100 69.35 100 100 100 100 81.4 100 80.23 100 100 100 100 100 84.62 100 83.72 100 100 NA 100 100 100 100 66.67 100 100 100 77.78 85 100 100 100 100 100 87.18 75.68 100 NA 100 100 100 67.64 -32.36 0.0013 0.028452 K cassette DNAJC5 chr20 + chr20:62562376-62562817 chr20:62562376-62562461;chr20:62562536-62562817 chr20:62562462-62562535 43.48 18.75 28.57 8.82 27.78 0 11.11 23.81 22.94 28 32.14 0 22.73 20 11.76 20.75 50.98 31.25 32.88 21.21 24.75 11.11 26.97 35 13.04 20 21.88 22.37 24.59 27.46 26.67 21.21 20 43.82 24.24 36.73 33.33 35.94 30.26 45.76 24.56 47.06 16.39 17.39 25.86 27.69 18.87 26.25 28 21.15 22.73 28.3 35.71 28.95 26.58 21.7 31.25 41.98 29.41 24.74 31.03 45.24 26.53 27.27 25.93 33.33 34.29 21.21 38.89 57.33 28.26 38.64 40 38.46 29.63 38.36 43.75 41.56 20 34.78 17.57 32.1 10.84 26.51 45.83 27.27 11.11 28.57 27.59 24.34 19.05 32.35 19.05 31.82 32.46 28.21 7.14 27.85 45.16 20.61 27.36 31.67 25 25 42.86 31.08 41.1 23.33 29.37 15.38 35.78 10.53 25.49 18.92 20.71 25 25.42 17.24 17.65 27.42 22.22 28.05 21.26 26.09 25.49 21.62 29.73 NA 26.26 34.78 22.22 27.78 35.48 30 15.79 31.68 35.48 36.67 13.33 26.56 10.53 22.58 0 26.72 35.71 23.39 26.09 31.37 26.09 17.95 NA 27.94 24 25.53 29.79 48.15 44.44 25.4 16.33 48.33 33.87 36.11 37.04 23.64 7.89 34.43 23.53 32.65 25.71 32.14 36.59 32.93 26.58 41.24 14.66 0.002029 0.039671 K cassette DNM1L chr12 + chr12:32890096-32892997;chr12:32890096-32891197 chr12:32890096-32890798;chr12:32890877-32891197,chr12:32890877-32892997 chr12:32890799-32890876 17.24 30 17.59 30.16 20.31 26.09 37.5 19.77 29.63 23.19 18.81 13.46 31.43 27.78 16.67 32.43 33.8 28.92 21.24 27.27 24.05 26.32 28.07 31.88 15.69 21.54 20.83 29.67 25 44.44 20.63 34.78 NA 45.45 16.3 14.81 27.63 23.6 32.31 16.33 25 19.15 15.22 18.75 37.5 21.57 24.14 35.29 24 31.82 28.24 25.29 28.57 20 26.42 45.83 26.92 41.51 26.87 26.58 26.79 33.33 32.08 19.67 35.14 29.79 29.69 25 31.88 14.89 35.29 36.76 24.1 38.71 25 21.54 30.65 25.81 33.8 24.8 34.62 50 28.89 38.6 27.5 34.29 16.28 50 24 27.54 38.89 12.5 26.09 19.64 19.44 26.67 38.81 31.68 23.81 48.72 24.62 33.33 24.73 21.43 36.63 40.48 24.75 34.83 21.05 25 22.81 38.18 39.62 NA 28.12 28.05 30 35.14 23.08 28.99 41.67 29.69 31.4 26.44 33.33 35.59 23.91 27.03 16.67 38.71 20.56 18.37 10.71 41.51 28.3 29.41 25.29 37.84 28.57 27.27 46.43 23.61 46.88 24 27.14 16.13 17.39 20.31 NA 6.98 18.6 16.28 31.51 27.69 30.77 32.69 28.57 38 52.05 16.07 25.4 28.57 21.43 29.55 30.38 14.63 24 33.33 28.26 32.08 39.39 17.07 27.63 15.48 -12.15 0.000644 0.016955 K alternative_acceptor DNMT1 chr19 - chr19:10291206-10291453 chr19:10291246-10291453 chr19:10291206-10291245 chr19:10291205-10291206 100 100 100 100 100 100 71.43 100 100 100 93.71 100 100 100 91.45 87.72 100 100 100 79.17 92.11 100 92.71 91.23 100 100 83.69 100 89.89 100 93.18 100 100 85.57 100 72.97 86.24 92.41 88.89 75.9 88.1 94.32 100 90.28 79.55 87.94 88.71 92.76 91.55 88.24 95.57 62.03 100 91.98 94.44 82.35 100 100 90.48 89.63 81.03 82.28 84.62 100 91.58 88.14 88.64 85.39 90.54 72.83 88.41 93.2 100 89.69 88.75 100 100 93.75 83.33 87.9 100 89.71 100 100 91.58 100 89.55 92.71 84.91 90.91 100 56.69 100 100 92.71 100 93.18 89.82 90.57 82.31 100 100 91.94 100 87.5 100 92.68 84.54 86.72 100 89.71 100 90.38 100 91.72 91.23 100 100 100 92.96 100 87.7 91.27 87.38 100 91.45 90.16 100 89.71 100 91.75 100 92.31 100 85.53 91.87 100 83.93 100 100 87.18 83.67 100 89.12 100 88.6 100 83.96 100 85.12 100 100 86.27 84.04 87.06 100 89.25 88.71 100 59.46 91.38 87.5 92.52 100 100 89.83 90.82 87.1 93.63 90.54 78.31 100 92.52 67.43 -25.09 0.000021 0.002101 K cassette DNMT3B chr20 + chr20:31372666-31375035 chr20:31372666-31374307;chr20:31374434-31375035 chr20:31374308-31374433 NA NA NA 66.67 NA NA NA 100 100 100 NA NA 72.22 NA NA 100 63.89 NA 100 100 100 NA NA 100 NA NA 100 NA 100 NA 89.13 86.49 100 100 NA 65 100 100 NA 69.44 NA 92.75 100 100 NA 100 100 100 NA 100 100 NA 100 100 88.1 NA 100 100 89.13 NA 100 100 NA 100 NA NA 100 100 NA 78.43 100 100 100 85 NA NA 100 100 92.06 100 NA 100 100 100 91.8 100 85.42 93.88 100 NA 100 NA 100 NA 89.8 NA 100 93.07 100 92.08 100 100 100 100 100 88.89 100 92.98 100 NA 100 100 78.38 100 72.73 100 100 100 NA 92.31 89.15 100 100 88.68 NA 100 NA 100 NA NA 100 100 100 100 NA NA 100 NA NA NA 100 100 100 87.67 100 100 100 100 100 NA 100 NA 100 100 100 100 100 100 100 64 100 NA 100 100 78.26 NA 100 100 100 100 100 100 100 67.22 -32.78 0.000009 0.000623 N alternative_acceptor DOCK10 chr2 - chr2:225717808-225719679 chr2:225717840-225719679 chr2:225717808-225717839 chr2:225717807-225717808 NA 100 100 100 100 NA NA NA 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 NA 100 100 100 100 100 100 NA 100 100 100 100 84.21 NA NA 100 100 100 100 NA 100 100 100 100 100 100 NA NA 100 100 100 100 100 100 100 100 100 82.35 100 NA NA NA 100 100 100 100 NA 100 100 100 100 100 89.69 100 100 100 100 100 100 NA 100 100 87.67 100 100 100 100 100 NA 100 100 100 100 100 NA 100 100 100 100 NA 100 NA 91.23 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 NA NA NA 100 100 NA 100 100 NA 100 100 78.79 100 100 100 100 100 100 100 100 100 100 NA 100 100 89.69 -10.31 0 0 N alternative_acceptor DOCK5 chr8 + chr8:25126402-25126609;chr8:25126402-25132901;chr8:25126402-25132070 chr8:25126402-25128305 chr8:25126610-25128305;chr8:25128306-25132070;chr8:25132071-25132901 chr8:25128305-25128306;chr8:25132070-25132071;chr8:25132901-25132902 15.79 41.46 14.06 20 19.23 11.11 25 32.14 21.24 11.56 14.13 16.03 NA 27.36 19.51 26.19 29.8 28.57 11.45 8.7 22.02 18 15.38 9.62 10 NA 13.64 22.03 10.83 25.47 26.58 15.79 11.76 12.24 11.11 NA 14.63 18.6 13.91 36.96 26 25.51 21.69 12.68 16.67 10.48 15.38 12.63 19.23 20.51 9.23 38.46 15.52 24.53 8.7 18.06 14.73 11.71 10 18.98 12.62 15.19 15.91 23.3 18.81 14.71 11.32 12.5 14.04 27.41 19.1 20.75 17.58 10.47 24.77 18.6 12.5 15.66 12 28.3 14.49 21.43 NA 17.95 26.09 NA 28.1 13.73 23.89 11.11 35.11 45.71 35.71 28.46 10.75 18.18 15.48 15.15 13.21 40.78 13.16 32.95 18.75 NA 23.2 29.09 14.93 13.64 29.41 21.11 10.98 17.07 17.12 22.22 18.18 21.54 10 24.47 16.25 29.89 27 22.22 5.81 24.44 12 23.4 13.25 31.86 22.92 14.81 14.46 18.64 16.36 11.27 21.74 14.29 18.75 42.22 19.05 36.73 35.34 19.64 19.57 6.82 16.88 25 14.29 18.92 NA 14.46 NA 19.35 23.46 37.5 10.69 23.95 13.43 20 16.88 32.85 10.43 10.94 11.11 11.32 12.12 11.76 10.64 20.98 10.61 10.26 12 20.21 16.77 36.96 20.19 0.000522 0.02676 N cassette DOCK5 chr8 + chr8:25224487-25226086 chr8:25224487-25225707;chr8:25225767-25226086 chr8:25225708-25225766 100 100 100 NA 100 NA 100 68 77.27 100 100 NA NA 100 100 100 72.22 82.69 100 NA 86 100 100 100 100 NA 100 83.67 78.12 100 87.31 86.67 100 89.23 77.14 NA 100 100 91.53 83.78 100 81.16 86.27 100 100 100 100 89.36 100 100 100 63.93 100 91.93 100 100 100 100 100 100 100 86.24 84.09 84.54 100 100 100 84.78 88.33 63.64 74 78.26 100 80.56 100 87.72 100 100 100 72.73 100 100 NA 100 78.57 NA 100 100 73.91 100 100 77.19 78.57 100 100 100 74.07 85.71 100 76.06 86.11 84.04 80.49 NA 73.33 100 85.42 100 100 100 100 100 77.08 100 NA 100 87.5 76.56 100 100 73.53 83.67 100 82.69 100 100 100 100 100 100 100 100 100 100 100 100 100 73.47 100 100 100 100 100 100 100 100 100 100 NA 100 NA 100 82.05 100 79.69 100 70.59 89.02 100 66.67 100 100 79.49 85.45 100 100 87.76 91.67 100 100 100 83.93 100 66.67 -33.33 0.00009 0.00453 N coord_cassette DONSON chr21 - chr21:34954362-34956895 chr21:34954362-34954470;chr21:34954553-34955793;chr21:34955973-34956895 chr21:34954471-34954552;chr21:34955794-34955972 100 100 100 100 100 NA 100 100 100 100 90.74 NA 100 100 100 NA 100 100 100 100 52.17 100 100 57.89 100 100 100 77.42 100 100 100 100 100 100 90 42.86 73.08 100 100 54.17 NA 100 100 64.52 100 69.23 NA 100 NA 100 86 75 NA 100 100 100 100 100 79.17 100 100 100 100 100 100 100 100 77.27 100 69.57 100 100 82.14 80.77 100 100 NA 100 NA 100 NA 100 NA 75 89.55 NA 100 70.59 100 81.82 NA 100 100 64 100 NA 100 82.86 87.8 100 84.85 78.26 68.97 100 100 72.22 100 66.67 100 100 100 100 100 NA 72.41 100 78.38 87.93 100 100 100 100 85.11 100 82.86 100 100 100 85 100 100 100 65.12 100 100 100 100 100 68.89 NA NA 100 100 100 100 100 NA 100 NA 60.42 100 NA 100 100 66.67 82.76 100 100 100 57.89 70 100 73.33 100 100 100 63.16 100 100 63.16 100 100 100 63.73 -36.27 0.000293 0.01325 N cassette DONSON chr21 - chr21:34954362-34956895 chr21:34954362-34954470;chr21:34954553-34956895 chr21:34954471-34954552 100 100 100 100 100 NA 100 100 100 NA 85.29 100 NA 100 100 NA 100 100 100 NA 52.17 100 100 38.46 100 100 100 68.18 NA NA NA NA 100 100 82.14 46.67 68.18 100 100 52.17 NA 100 NA 52.17 100 50 NA 100 NA NA 77.42 71.43 NA 100 100 100 100 100 77.27 100 NA 100 100 100 100 100 100 75 100 68.18 100 NA 80 77.27 100 NA NA 100 NA 100 NA 100 NA 61.54 84.09 NA 100 54.55 100 78.26 NA 100 100 52.63 100 NA 100 82.86 86.11 100 78.26 64.29 68.97 100 100 70.59 100 55 100 100 100 NA 100 NA 68 100 75 85.11 NA 100 100 100 80 100 79.31 100 NA NA 78.05 100 100 100 63.41 100 NA 100 100 100 41.67 NA 100 100 NA 100 100 100 NA 100 100 34.48 NA NA 100 100 69.57 78.26 100 100 100 50 63.41 100 68 NA 100 100 68.18 NA 100 58.82 100 NA 100 60.18 -39.82 0.001498 0.031595 N cassette DOPEY1 chr6 + chr6:83863340-83863898 chr6:83863340-83863612;chr6:83863763-83863898 chr6:83863613-83863762 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 NA NA 100 100 100 100 100 100 NA 100 100 76.19 100 80.65 100 83.33 80.77 100 81.25 100 100 100 100 100 100 100 100 74 100 100 100 100 100 100 100 83.87 100 100 100 100 100 100 100 100 100 81.58 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88 NA 100 100 100 100 100 100 100 100 100 100 100 88.46 100 100 100 100 100 82.76 100 100 87.5 100 NA 100 100 100 86.49 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 NA 100 100 100 100 100 NA 100 NA NA 100 100 100 100 100 100 100 69.23 100 100 100 79.17 100 100 100 100 100 100 100 100 100 78.88 -21.12 0 0 K cassette DPH5 chr1 - chr1:101456185-101460665;chr1:101456188-101460665 chr1:101456185-101458192,chr1:101456188-101458192;chr1:101458297-101460665 chr1:101458193-101458296 100 79.07 100 80 82.56 100 92.86 79.71 100 87.4 100 NA 100 100 86.71 100 100 100 88.68 100 80.49 100 100 100 88.57 72.22 100 87.5 75 100 100 87.14 100 100 72.73 68 90.12 88.18 82.05 84 100 89.87 100 86.17 100 100 91.14 85.42 81.25 82.56 71.11 84.21 89.66 83.58 78.26 100 100 100 100 90.2 100 100 86.84 100 100 100 89.09 100 91.25 76.6 100 100 87.5 90.77 86.15 91.25 100 91.67 100 83.72 86.96 100 100 100 100 89.55 100 91.18 87.5 84.48 100 70.59 100 100 93.24 65.38 86.96 86.36 100 100 85.58 85.53 100 86.79 90.67 85.11 89.19 84.04 91.18 100 86.27 86.11 88.89 100 81.58 100 100 92.42 100 100 75.68 84.91 77.78 85.05 90.91 82.46 100 84 86.49 100 85.71 100 75 100 100 100 84 100 100 100 74.07 84.78 100 91.95 100 85.37 100 87.18 100 100 100 100 100 91.55 86.84 100 88.68 72.22 83.64 84.85 84.21 80.95 91.89 88 82.35 82.98 79.37 100 91.58 100 100 100 91.56 80.3 -11.27 0.00065 0.017043 K cassette DTNB chr2 - chr2:25803696-25851039;chr2:25803696-25830104 chr2:25803696-25818954;chr2:25819110-25851039,chr2:25819110-25830104 chr2:25818955-25819109 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 75 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 80.65 85.33 100 86.96 100 100 100 89.83 100 100 100 89.13 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 76.19 100 78.85 100 100 100 86.49 82.5 100 100 100 100 100 86.11 100 80.95 100 100 100 100 100 100 83.33 100 100 100 100 85.45 88.37 100 100 100 100 100 77.27 89.8 100 100 100 100 100 100 100 100 100 100 100 100 86.27 100 100 92.54 100 100 90.48 85.71 100 100 100 100 100 100 100 100 100 100 100 100 82.76 100 NA 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 83.72 82.93 100 100 100 100 100 100 100 100 100 100 100 100 100 83.33 -16.67 0.000004 0.000281 K cassette DYRK4 chr12 + chr12:4714253-4719320 chr12:4714253-4716492;chr12:4716554-4719320 chr12:4716493-4716553 NA 22.73 61.54 34.48 46.67 38.46 22.86 100 38.46 42.86 50 NA 33.33 37.5 41.46 NA 64.71 25.81 100 10 NA 43.75 44.44 52.38 50 40 NA 30.3 43.75 30 23.53 NA 30.43 44.83 42.86 64.71 50 56.67 42.42 100 NA 21.05 35 30.77 34.78 NA 55.26 26.32 42.11 100 52.17 100 63.16 100 22.73 28.57 NA NA 47.06 54.55 63.16 NA 50 38.46 44.44 58.33 46.43 30 39.29 41.18 36 31.58 39.13 52.38 27.27 43.33 33.33 41.67 38.46 27.03 NA 58.82 58.33 46.67 50 39.13 56 52.38 66.67 40 50 58.33 46.67 36.36 27.27 NA 0 56.25 50 34.15 51.61 37.5 32.5 52.38 56.25 52.94 57.14 30.56 46.88 50 NA 44.44 60 40 24.32 46.34 41.18 63.64 100 35 38.1 50 34.78 56.67 31.25 26.83 NA 23.53 35.29 15.38 39.39 53.12 14.29 100 16.67 13.46 23.08 100 33.33 33.33 21.05 15.79 18.18 40.62 57.89 38.1 NA 35.29 22 NA 35.14 NA 35 65.22 43.75 57.89 NA 33.33 46.15 66.67 NA 26.32 50 53.33 17.65 36.84 31.43 45.45 60.87 61.54 53.85 66.67 41.46 65.69 24.23 0.002322 0.04374 N cassette EFCAB2 chr1 + chr1:245133746-245222687;chr1:245133746-245180543 chr1:245133746-245165422;chr1:245165535-245180543,chr1:245165535-245222687 chr1:245165423-245165534 NA 17.39 10.34 11.11 50 30.77 NA 26.47 36 NA 42.11 100 50 37.5 20 36 NA 27.08 21.05 20 NA 11.76 100 25 33.33 NA 41.94 31.71 32 NA 26.92 36.59 29.69 31.82 100 5.88 NA 32.69 29.17 11.11 40 16.67 22.73 16.67 NA 20 NA 28.57 33.33 26.09 NA 13.33 20.51 33.33 21.43 45.95 NA NA 26.09 37.5 32.14 26.79 NA 28.57 29.73 28.57 15.15 35.71 45.45 10.53 35.71 28 35 33.33 28.57 25.93 54.55 53.57 35.71 32.69 22.86 33.33 31.58 26.67 37.5 20 NA 50 36.36 53.33 NA 27.08 60 NA 33.33 NA NA 19.35 35.71 NA NA 50 NA 25.81 25.71 16.67 21.67 26.09 22.22 33.33 NA 20 NA 66.67 33.33 20 12 22.73 NA 26.67 36.36 26.19 38.46 24 30.43 NA 33.33 15.38 31.82 9.68 10.34 20.83 40 29.03 NA NA NA 31.03 38.1 NA 38.78 35.14 NA 31.25 23.08 10 36.67 42.86 13.64 NA NA NA 23.08 35.19 27.27 21.43 44.44 40 NA 15.15 29.41 100 15 29.63 9.09 26.19 29.41 18.18 23.53 NA 30.77 40 30.08 12.22 -17.86 0.001085 0.024767 K cassette EIF4A2 chr3 + chr3:186502486-186503671 chr3:186502486-186502750;chr3:186502891-186503671 chr3:186502751-186502890 58.46 64.64 71.38 59.81 55.89 50.15 43.11 63.78 79.94 78.01 75.48 84.73 74.72 73.84 79.64 79.52 67.4 71.1 78.65 77.36 78.78 66.67 68.6 71.57 82.63 71.46 73.57 68.03 78.8 80.28 79.59 70.15 58.1 71.57 77.3 63.11 72.09 73.08 78.77 66.73 57.44 82.63 74.37 76.49 58.58 87.07 72.77 76.84 84.25 84.12 76.68 51.52 70.57 62.71 75.67 69.05 52.69 83.01 73.48 75.49 80.7 65.29 65.02 79.02 76.38 66.54 78.88 64.81 78.93 63.89 68.09 76.37 82.71 78.66 76.25 73.15 66.59 68.74 81.23 74.55 65.84 73.67 74.81 61.46 69.29 78.22 79.75 71.21 73.89 79.11 80.57 52.05 75.5 66.91 73.61 71.66 76.48 64.94 81.85 84.63 82.62 80.25 83.79 76.13 79.52 83 81.83 83.96 79.03 72.06 84.68 74.03 73.49 77.39 76.7 75.67 81.4 78.13 71.34 80.96 80.19 76.54 78.33 73.81 77.84 78.88 77.7 64.11 81.07 67.7 80.7 75.73 77.37 67.27 80.67 75.58 71.38 65.42 73.66 67.37 64.46 73.03 79.61 79.54 67.02 76.54 66.29 80.1 65.77 79.41 81.47 79.82 79.69 69.66 52.18 73.21 72.01 57.07 83.7 63.4 73.04 72.76 79.08 74 57.86 83.11 80.51 71.4 77.64 69.94 67.77 72.81 75.48 63.25 -12.23 0.000473 0.014107 K cassette EIF4A2 chr3 + chr3:186505672-186506913 chr3:186505672-186506098;chr3:186506206-186506913 chr3:186506099-186506205 29.81 20.36 30.95 34.84 38.63 54.87 62.75 40.24 35.74 16.65 36.04 17.44 39.57 35.36 23.39 32.41 62.69 29.43 33.21 48.97 35.8 31.77 31.68 35.46 34.81 26.05 22.52 41.35 36.18 29.84 25.83 34.96 47.87 58.54 24.07 49.13 39.63 46.76 39.63 41.29 64.81 24.89 42.11 28.02 48.81 24.9 38.53 40.46 31.23 33.9 38.54 80.64 36.76 28.23 29.48 51.7 41.96 32.78 38.82 37.53 40.5 55.15 47.01 25.98 39.49 45.97 32.91 51.82 32.12 56.36 47.57 38.36 30.31 37.5 35.75 31.12 53.09 44.66 40.42 45.22 45.97 36.33 36.12 51.35 37.83 19.41 33.84 43.89 45.42 48.45 41.74 53.51 39.19 34.3 46.39 32.61 26.34 55.76 28.27 37.54 29.43 36.26 37.31 51.11 29.5 27.65 32.31 33.37 33.98 16.19 29.88 46.43 27.19 17.5 25.33 38.77 35.11 31.34 35.5 34.4 36.64 45.41 33.79 46.1 35.7 39.95 47.96 50.67 46.15 41.59 21.24 18.31 26.16 19.46 26.73 19.02 41.15 50.65 32.32 27.92 34.1 37.34 21.08 44.6 38.33 37.76 48.4 37.26 37.26 17.92 26.55 19.1 41.43 40.97 61.99 30.32 51.38 60.66 27.85 50.64 43.35 37.27 33.48 43.98 44.1 37.18 32.92 41.92 39.3 45.87 57.8 39.2 36.76 52.08 15.32 0.000917 0.021935 K alternative_acceptor ELF2 chr4 - chr4:139993158-139994607 chr4:139993194-139994607 chr4:139993158-139993193 chr4:139993157-139993158 25.71 47.78 24.14 25.19 26.09 7.89 13.24 25.24 40 27.12 36.14 0 27.12 35.96 26.32 36.62 21.88 25 32.81 50 33.72 29.55 28.36 29.73 26.77 12.07 22.97 13.59 34.33 24.44 57.81 27.63 25.58 20.93 21.67 6.98 24.32 21.88 20.83 14.86 22.41 20.62 32.93 29.36 33.33 28.48 24.39 38.1 18.84 34.83 43.84 12.73 27.5 12.75 30.61 29.82 6.36 36.67 33.33 19.78 22.58 14.53 13.64 12.94 19.35 22.41 34.72 17.12 18.1 13.39 17.89 20.69 25.93 26.77 21.69 29.07 22.09 21.21 34.83 19.49 16.85 28.05 34.72 16.28 28.17 50.98 32.76 20.48 19.42 37.63 50 18.18 28.09 24.14 31.08 34.43 43.68 18.6 29.29 36.17 31.11 21.9 34.62 27.27 15.38 41.67 28.78 23.48 33.82 29.41 26.72 26.67 30.49 34.15 35.37 27.88 36.36 30 16 37.19 25.93 20.69 33.33 19.48 23.53 34.62 40.91 32.14 20 28.41 27 29.89 29.33 27.69 22.22 18.03 32.08 16.46 20.99 27.08 32.95 32.39 43.59 20 18.58 22.68 20.99 28.04 20.41 21.43 37.5 11.11 28.4 28.95 18.37 32.79 30 23 36.78 16.28 22.45 27.05 38.46 24.51 15.31 34.04 31.13 22.52 24.3 29.63 17.05 16 26.77 14.12 -12.64 0.000325 0.021208 K cassette ELK1 chrX - chrX:47500875-47509821 chrX:47500875-47509319;chrX:47509426-47509821 chrX:47509320-47509425 NA 64.71 50 50 NA 35.29 79.31 100 100 NA 42.86 NA 50 40 20 57.14 45 48 33.33 NA 55.17 NA 35.71 48 42.86 69.23 58.82 52.63 53.33 33.33 61.54 31.58 NA 40.48 NA 26.67 47.62 54.29 50 14.29 NA NA 38.46 NA NA 34.62 59.26 50 29.17 50 45 31.82 65 50 69.57 55 100 59.09 48.39 60.71 NA NA 47.37 53.33 40.91 NA 47.06 43.48 52.38 33.33 41.38 54.55 25 58.82 52.63 45 45.45 51.85 33.33 44.44 100 100 50 46.67 23.53 NA 47.17 51.52 51.52 43.75 57.89 NA NA NA 56.52 NA NA 27.91 63.89 54.43 26.92 45.71 54.29 60 59.46 48.28 58.33 42.86 46.81 36.36 61.9 39.13 62.5 51.52 56.67 40 31.25 69.23 53.85 40 62.07 62.5 53.12 40 50 57.14 50 NA 40.91 NA 36 44.44 53.85 50 NA 34.29 27.27 NA 48.15 NA 46.15 26.32 26.67 38.6 43.75 45.16 NA 51.72 57.81 NA NA 100 43.48 33.33 63.64 100 33.33 72.22 57.14 28.57 43.75 27.27 30.77 50 50 38.89 48 60 52 100 43.75 61.54 50 28.57 -21.43 0.000947 0.022339 N cassette ELMO2 chr20 - chr20:45023172-45035186;chr20:45023143-45035186 chr20:45023172-45027335,chr20:45023143-45027335;chr20:45027411-45035186 chr20:45027336-45027410 NA 40.48 47.73 16.67 100 NA NA NA 77.78 55.56 60.78 100 40.74 51.43 62.96 39.13 64.52 52.94 66.67 NA 51.02 46.43 60 67.5 44.83 100 38.89 56.25 47.92 63.24 75 100 100 69.57 63.77 NA 52.17 33.33 61.76 41.18 31.43 75 62.5 44.83 NA 100 100 71.43 42.42 50 55 37.5 41.18 67.74 48.65 57.89 100 63.16 66.67 44.44 NA 100 54.17 71.43 77.14 100 66.67 65.52 70.59 20.59 48 56.52 69.7 52.17 52.83 45.71 52.38 100 63.16 58.97 61.54 52.17 30.56 100 100 NA 100 68.42 100 60 75 NA NA 56 NA 71.11 60 67.86 70.83 100 100 70 35.14 68.42 69.57 48.94 41.94 66.67 65.62 NA 44.68 50 42.11 70.83 100 79.49 31.25 40.91 100 77.27 66.67 56.67 63.16 78.79 41.03 74.29 65.22 68.75 58.33 20 67.5 100 100 NA 41.67 71.79 50 66.67 NA 56 NA 52.63 NA 51.11 100 52.27 NA 100 NA 100 NA 100 100 NA 42.86 64.29 NA 44.68 78.26 28.57 37.74 NA 35.14 74.29 34.78 56.25 70.83 50 54.55 47.37 46.67 43.59 63.06 33.03 -30.03 0.002301 0.043408 N cassette EXOSC2 chr9 + chr9:133573015-133574715 chr9:133573015-133573548;chr9:133573639-133574715 chr9:133573549-133573638 100 100 87.69 100 100 100 100 70.18 81.13 100 100 NA 80.36 100 88.1 78.38 80.56 84.62 88.46 100 100 100 100 89.06 84 76.09 87.93 89.86 100 100 88.89 83.72 100 100 100 71.74 100 86.24 86.44 73.13 100 84.44 100 88.71 100 91.95 100 88.89 79.69 79.69 100 89.06 82.93 78.26 100 100 100 100 100 100 100 87.5 70.97 100 100 84.13 87.04 94.12 100 85.92 100 88.89 91.67 89.74 100 88.24 82.35 86.89 100 89.53 80 84.62 82.5 100 88.24 100 100 100 86.76 86.14 100 76.92 100 86.67 90.74 100 100 100 100 93.41 92.38 85.29 84.72 82 100 100 94.25 100 88.57 100 100 74.68 100 84.38 90.12 100 76.19 88.06 100 93.26 84.13 100 100 88.04 82.61 100 85.37 100 89.61 65.52 93.42 100 100 100 100 100 100 75 100 100 100 100 100 92.42 81.03 100 81.25 100 52.94 100 100 100 87.78 100 83.64 100 100 80.65 90.43 75.38 86.96 100 91.01 87.5 89.13 100 85.9 83.33 84.21 100 72.34 100 97.12 76.15 -20.97 0.001082 0.024734 K cassette EXOSC3 chr9 - chr9:37780878-37783910 chr9:37780878-37781982;chr9:37782135-37783910 chr9:37781983-37782134 100 88.41 88.57 100 82.81 50 52.94 100 100 100 100 100 100 100 100 100 100 100 89.83 100 86.89 100 100 90 81.08 100 100 87.5 100 100 100 100 100 100 81.71 75 100 90.62 87.04 84.75 76 87.23 100 100 100 100 100 88.75 100 100 90 82.81 100 86.79 89.58 100 43.33 100 100 85 100 87.18 87.5 100 100 100 100 100 87.72 80 100 100 100 85.14 77.42 89.55 81.58 84.91 100 86.76 100 92.42 87.76 80.77 100 100 100 91.07 82.76 90.91 100 100 100 100 100 100 100 88.89 93.59 100 90.2 83.33 91.3 100 100 87.14 87.91 100 100 100 100 90.77 100 58.97 90.67 100 85.45 100 100 100 100 79.17 100 86.76 100 100 100 76 91.03 100 89.81 100 100 100 100 84.3 100 100 80.3 100 86.27 100 100 100 100 100 100 100 100 100 100 100 92.5 89.77 82.14 100 85.71 79.41 79.1 80 100 100 86.21 100 100 100 88.31 100 83.33 100 100 100 100 81.41 -18.59 0.00235 0.044119 N alternative_acceptor EZH1 chr17 - chr17:40854980-40855757 chr17:40855044-40855757 chr17:40854980-40855043 chr17:40854979-40854980 NA 25 34.88 51.72 63.33 NA 67.39 100 37.93 21.43 40.91 8.45 60.87 41.03 NA 45.83 73.33 51.72 45.24 NA 26.53 NA 52.38 48.39 37.5 37.5 47.37 34.78 57.5 37.1 41.67 40.62 100 39.39 38.1 22.73 61.54 54.55 47.22 34.62 58.33 49.02 59.09 34.48 60 41.82 50 34.78 42.5 28.57 37.5 28.57 36.36 50 37.5 39.39 NA 50 40.91 42.22 34.69 43.48 45.71 50 43.59 60 51.85 39.39 54.55 33.33 56.9 56.67 52.63 46.94 60.87 40.62 67.86 39.29 40 42.86 52.63 59.38 66.67 62.16 51.85 41.18 100 40 63.89 38.46 51.72 NA 66.67 NA 50.91 71.43 44.44 45.45 30.3 57.69 40.68 51.72 44.44 54.76 59.09 36.51 50 45.76 46.15 41.18 45 20 32.89 34.78 34.48 48.98 50 40.38 37.5 48.65 45 52.78 51.28 61.76 60 45.24 52.63 52.17 41.67 59.26 10.81 NA 44 NA 29.73 26.67 60.87 60 28.57 68.42 41.94 38 NA 52.73 57.14 29.63 45 37.93 NA 100 3.7 36.67 58.06 57.89 57.14 47.62 38.1 55.88 37.5 25.93 68.42 56 66.67 46.43 100 NA 45.83 43.33 47.22 52.17 61.54 18.52 46.43 28.57 -17.86 0.001124 0.046582 K cassette EZH2 chr7 - chr7:148515210-148516687 chr7:148515210-148516069;chr7:148516152-148516687 chr7:148516070-148516151 NA 70.37 15.87 76.92 29.09 22.73 34.25 24.14 25.49 15.38 35.85 NA 16.67 38.1 14.29 60.71 32.61 56.41 18.64 16.67 10.34 NA 23.33 14.86 0 21.74 29.79 21.57 28.12 41.18 20 33.33 15 28.89 7.14 60 24.64 30.38 22.22 100 15.38 16.67 12.5 40.91 24.29 50 12.5 17.5 30 29.17 40 41.51 25.58 41.67 42.86 34.88 18.75 51.43 18.52 23.53 28.89 36.67 17.39 6.25 18.06 33.33 24.14 29.63 24 32.43 27.78 50 36 39.47 31.82 25.49 19.51 0 26.09 34.92 24 43.75 61.02 6.9 23.68 100 48.98 24.19 28.75 17.17 21.74 67.21 37.93 37.5 26.67 18.18 63.64 16.05 27.66 26.09 42.42 34.15 19.15 18.42 44.44 40.91 27.71 21.05 35 60.87 38.89 45.24 67.9 7.14 13.33 56.25 35.94 41.3 35.29 35.85 31.58 18.99 66.15 34 26.15 28.57 34.78 61.11 17.46 45.45 15.38 13.33 21.05 27.27 16.67 11.36 19.05 45 16.18 36.36 58.7 30.77 27.27 21.7 23.08 44.83 35 40.62 38.46 40.74 NA NA 25 59.04 24 47.06 21.57 39.02 52.17 62.75 11.84 41.86 69.01 30.23 52.63 35.71 23.73 31.25 16.51 26.83 22.22 28.12 28.12 61.38 33.25 0.001967 0.039079 N alternative_acceptor FAM111A chr11 + chr11:58913330-58916176;chr11:58913330-58916308 chr11:58913330-58916269 chr11:58916177-58916269;chr11:58916270-58916308 chr11:58916269-58916270;chr11:58916308-58916309 19.05 37.41 21.15 15.49 37.68 NA 16.67 40.82 30.93 43.86 44.51 NA 27.45 40 40 40 22.81 25 45.31 20 35.11 10.91 33.33 30.25 26.09 32 42.15 23.33 37.31 38.71 35.63 46.88 21.13 29.76 42.17 20.37 34.21 35.58 35.21 27.42 33.33 52.31 27.42 36.67 32.88 41.54 44 25.37 35.85 35.85 38.89 17.57 30.56 31.97 32.84 23.53 12 44.78 36.92 26.55 30 28.79 32.91 39.39 32.39 33.33 29.69 25 36.92 17.65 28.36 40.82 39.64 38.95 28.75 33.65 36.36 27.5 35.71 30.56 25 43.64 30.95 50.91 25.61 23.81 24.19 28.57 32.35 37.8 73.91 21.6 36.36 30.49 32.63 53.26 36.36 33.78 46.15 29.73 38.1 35.19 34.69 32.26 33.71 13.85 30.92 34.33 33.66 46.67 40.45 31.03 36.91 13.33 42.11 53.33 28.81 27.06 33.77 37.1 21.05 41.32 28.91 27.68 38.27 29.69 36.96 26.83 36.89 32.38 44.71 34.15 56.06 37.5 40.43 32.76 44.44 36.11 36.05 4.88 28.85 42.59 50 33.77 46.58 35.92 30.77 44.3 NA 38.89 17.39 85.71 37.5 29.03 29.41 33.68 32.95 27.78 28.38 27.42 39.18 41.03 38.61 41.18 10.53 6.67 43.68 38.71 35.42 29.03 32.56 35.9 34.18 20.98 -13.2 0.000807 0.036054 N cassette FAM193A chr4 + chr4:2674100-2692424 chr4:2674100-2691232;chr4:2691432-2692424 chr4:2691233-2691431 100 100 100 86.15 100 100 64.86 100 100 90.59 100 100 100 100 100 92.54 100 88.78 92.42 100 100 100 100 100 90.77 100 100 83.87 89.71 92.54 100 100 100 100 100 80 100 100 85.33 82.02 88.71 100 85.25 100 100 92.31 100 88.1 86.57 100 100 84.21 100 100 100 100 100 100 100 91.18 100 100 92.65 91.57 100 100 90.54 91.18 89.33 90.41 85.92 90.62 91.55 93.06 100 100 87.04 100 100 100 100 89.55 90.38 100 100 100 100 100 91.03 90.28 100 100 100 100 100 87.5 100 100 100 100 92.06 91.67 90.41 100 100 91.36 100 100 91.67 100 100 100 88.73 100 100 100 90.79 100 100 100 100 90.16 100 100 86.67 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.18 100 100 85.19 100 100 100 100 100 100 100 100 100 85.71 100 100 83.08 93.51 92.19 92.96 100 88.73 100 80.88 100 100 92.31 100 100 86.44 86.89 100 87.31 -12.69 0.00179 0.036336 K cassette FAM193B chr5 - chr5:176958523-176959443 chr5:176958523-176958953;chr5:176959133-176959443 chr5:176958954-176959132 60.67 70.45 55.56 61.36 74.19 54.55 57.08 58.33 50 73.68 71.79 100 63.64 55 70.83 68.57 57.63 66.07 64.15 NA 62.07 50 100 60.34 70.18 35.71 100 55 57.14 53.7 40.48 48.57 52.63 56.88 76.92 54 64.44 45.45 54.9 40.38 57.5 100 45.83 57.5 58.73 49.15 37.5 52.38 56 67.14 46.34 41.67 59.46 63.16 70.59 62.9 41.67 65.12 60.78 70.51 70 65.69 41.94 37.5 56.96 57.89 58.51 53.49 61.54 47.5 50 68.85 74.76 56.38 64.58 79.63 60.26 57.14 50 48.08 62.96 65.62 57.5 59.02 74.68 80 NA 44.74 65.28 49.3 62.86 40 61.54 46.67 47.95 50 64.1 62.22 58.4 46.88 57.81 64.86 46.43 74.47 60.78 56.52 63.95 56.62 67.06 65.38 65.31 42.11 70.65 45.95 67.57 60.47 64.52 45.33 53.66 59.32 50 61.19 51.28 55.26 72.73 35.29 66 66.67 47.73 85.29 54.29 NA 63.16 73.47 52.94 100 68.29 63.46 59.09 100 64 58.97 100 54.26 64.86 66.04 41.38 61.54 51.43 100 NA NA 57.38 58.62 55.56 55.56 49.23 54.93 72.94 47.22 58.33 64.44 64.37 42.68 67.74 58.54 66.67 47.46 58.93 59.57 50 44.62 59.39 44.45 -14.95 0.000881 0.021404 N cassette FAM60A chr12 - chr12:31451159-31476877;chr12:31451159-31478957 chr12:31451159-31457915;chr12:31458058-31478957,chr12:31458058-31476877 chr12:31457916-31458057 100 72.41 60.36 83.61 68.75 100 49.09 76.04 46.67 33.82 29.09 100 61.9 52.38 53.49 53.06 66.67 54.17 37.35 65.22 35.29 45.83 100 67.74 62.86 52.08 NA 86.84 33.33 31.03 48.75 63.93 100 37.5 37.5 100 57.41 47.06 58.82 69.41 100 42.86 35.19 42.86 100 32.08 51.85 70.31 50 42.03 35.29 85.94 47.06 49.47 41.18 68.97 100 36.36 45.16 52.38 55.06 72.92 100 57.14 45.63 68 46.74 58.46 49.09 74.16 53.45 50 40.48 55.1 55.56 44.44 63.89 70.45 39.66 41.67 72.88 41.3 100 61.11 43.64 32.2 57.32 62.32 74.55 53.66 53.12 75.76 54.9 66 48.28 100 66.1 59.02 45.16 60.23 37.23 59.46 60 69.09 69.23 44.12 34.95 41.86 55 56.76 34.38 47.5 44 62.26 33.33 53.33 36.17 54.24 48.08 62.96 45.78 54.72 57.14 60.38 53.45 39.71 56.82 60 53.33 66.1 46.27 66.67 47.73 79.07 66.67 20 49.18 50 74.47 NA 73.12 60 44.64 41.59 71.79 48.72 59.26 54.17 62.07 NA 41.38 NA 49.52 51.72 65.62 54.55 44.44 70 38.6 71.67 69.44 58.97 34.57 68.25 64.47 61.54 52 38 54.95 56.36 71.88 56.9 54.55 74.96 20.41 0.001074 0.024591 N cassette FCGR2A chr1 + chr1:161479865-161483684 chr1:161479865-161480623;chr1:161480747-161483684 chr1:161480624-161480746 73.77 90.35 82.98 76.92 89.42 100 89.36 100 88.61 100 87.43 100 86.75 89.42 100 75 100 NA 83.02 74.65 87.66 100 82.25 100 84.46 87.84 84.48 93.17 93.39 92.29 90.45 100 80.15 87.33 76.6 71.71 83.95 80.28 89.51 79.57 93.95 NA 91.81 NA 85.83 77.78 100 84.11 85.45 88.71 85.61 70.11 84.43 100 90.62 100 88.33 100 100 91.49 78.57 86.05 94.91 74.51 84.38 100 100 92.09 90.17 69.4 92.05 100 100 78.79 87.7 90.78 91.9 82.05 NA 100 83.17 100 100 91.18 80.31 NA NA 100 87.33 79.91 100 68.22 78.26 76.62 89.71 85.19 100 72.22 NA NA 91.06 89.57 83.03 86.27 NA 90.32 100 81.58 91.52 100 84.78 71.06 85.71 100 91.27 91.86 90.7 84.13 100 100 77.42 89.57 93.22 100 100 84.57 89.57 100 83.44 NA 100 NA 83.96 NA 92.47 84.64 84.06 100 NA 90.55 100 100 100 85.92 82.39 92.1 82.76 89.83 NA 81.44 100 89.45 100 100 83.49 96.05 NA 86.92 100 76 83.02 83.54 82.47 85.29 83.52 86.43 100 83.87 85.96 82 NA 84.85 89.42 70.91 -18.51 0.00007 0.003779 N cassette FGD3 chr9 + chr9:95780498-95782598 chr9:95780498-95782112;chr9:95782144-95782598 chr9:95782113-95782143 84.15 84.62 88.52 67.57 100 60 50 100 86.29 100 89.42 100 78.12 93.92 100 100 79.17 87.66 86.32 100 100 100 100 90.1 90.83 79.74 100 83.82 100 90 90.09 83.87 100 89.11 89.42 77.01 75.9 87.06 100 71.56 73.96 88.06 87.5 100 76.42 90.53 95.12 84.04 82.61 88.44 91.21 64.86 100 100 91.8 81.4 78.57 91.46 93.26 88.42 93.33 100 69.81 76.92 78.82 100 92.77 80.6 82.35 76.82 80.51 89.36 89.36 83.64 84.7 92.21 75.71 100 100 86.75 75.81 90 68.75 78.43 90.91 91.95 100 100 82.14 100 100 47.37 100 77.27 83.13 82.95 67.82 84.29 100 100 100 87.32 86.25 81.05 88.03 80.47 94.07 100 89.05 100 88.72 78.33 84.21 100 100 86.92 87.91 100 100 85.03 71.79 87.5 84.58 82.41 100 82.8 78.41 100 84.38 71.6 95.28 100 87.67 100 88.67 92.22 90.91 75.28 90.67 84.93 78.05 100 100 90.23 100 88.48 83.33 86.49 100 100 100 91.74 89.74 100 77.27 94.16 100 83.48 89 62.89 80 91.14 86.84 78.26 55.56 92.42 100 88.46 92.94 84.15 70.77 84.54 89.11 68.21 -20.9 0.000152 0.006689 N cassette FGFR1OP chr6 + chr6:167416736-167417751 chr6:167416736-167417210;chr6:167417300-167417751 chr6:167417211-167417299 100 100 88.64 100 100 100 NA 100 76.92 100 100 NA 100 100 100 75 100 100 86.79 100 100 100 100 100 82.76 NA 100 70.97 100 100 100 100 100 82.26 100 60 82.93 67.61 100 100 100 100 100 100 100 76 100 85.71 100 100 87.72 62.86 100 73.81 100 100 100 100 100 79.07 79.55 67.8 100 63.64 64.06 100 79.59 70 100 74.58 100 83.33 76.47 100 69.57 80 100 100 78.79 56.1 100 100 100 100 75.76 61.36 100 75.61 71.74 100 100 46.88 74.19 60 68.97 100 100 100 70.45 71.15 84.48 71.43 75 69.23 65 73.08 72.5 72.88 76 100 80 85.29 88.37 69.57 100 86.57 83.87 74.58 62.16 76.36 75 100 100 100 63.46 70 70.37 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 88.64 75 73.91 100 100 NA 100 NA NA 75 100 75.68 60.61 62.79 79.55 100 53.66 75 100 100 100 72.73 100 100 78.72 90.91 64.38 80 100 100 61.43 -38.57 0.002296 0.043381 K cassette FIP1L1,PDGFRA chr4 + chr4:54244091-54245391 chr4:54244091-54245239;chr4:54245285-54245391 chr4:54245240-54245284 0 40 45.45 56.76 38.71 48.15 69.39 49.06 52.63 100 42.86 NA 46.67 25.81 52.94 50 61.4 34.15 47.83 40.74 30.43 NA 100 42.11 26.83 43.59 37.04 33.33 41.67 35 46.43 69.7 45 34.88 39.39 37.5 35 36.59 32.65 31.37 44.44 50.91 37.5 32.08 NA 44.68 31.71 51.9 34.48 36.92 28.57 26.67 44.44 31.88 54.76 41.18 NA 54.55 40.43 42.65 53.12 37.5 48.48 49.06 44.59 43.59 40 39.53 41.18 29.09 48 50 27.27 44.26 32.69 36.76 56 38.64 47.06 44.16 44.44 32.43 46.34 44.68 32.31 47.62 53.12 60 46.03 31.82 21.74 33.33 47.22 45 51.11 31.58 62.96 66.67 36.36 60 57.89 47.06 41.67 44.44 60.29 47.73 40.85 47.19 46.81 58.33 16.67 60.42 51.79 30.43 52.17 45.71 33.33 55.56 40 38.96 45.83 45.45 40 50 29.11 62.07 54.55 50 28.81 59.26 27.87 51.35 33.33 36.59 38.46 50 40 33.33 42.86 33.33 48.39 51.35 100 31.71 42.31 50 48.28 42.5 NA NA 63.64 100 46.15 59.18 48.98 24.39 51.52 47.37 25 34.62 40.54 44 46.81 40.43 63.16 50 44.83 54.55 41.79 38.78 38.89 47.62 44.59 32.35 -12.24 0.002372 0.044475 K cassette FLT3 chr13 - chr13:28599081-28601224 chr13:28599081-28599420;chr13:28599553-28601224 chr13:28599421-28599552 5.69 13.34 10.51 18.94 18.45 16.91 36.46 18.18 24.19 12.14 13.78 14.01 19.15 10.81 13.56 16.47 18.75 15.36 13.11 6.63 12.15 19.01 11.36 20.38 14.02 4.12 18.14 16.46 12.62 7.74 9.09 12.26 27.68 9.52 11.08 28.75 19.46 11.33 15.44 23.84 26.77 11.36 10.6 11.65 20.11 12.88 6.88 7.14 13.19 8.01 10.74 27.43 21.11 8.43 11.29 23.81 15.24 7.55 13.89 13.08 12.87 20 17.02 9.33 14.06 21.71 16.1 19.63 20.41 33.33 15.13 20.09 14.73 25 8.11 11.73 24 16.63 11.21 11.11 27.27 19.35 26.1 14.53 6 21.48 12.09 22.36 20.56 16.16 17.65 21.23 19.59 15.81 10.37 13.64 17.42 24.49 13.29 18.62 8.27 14.97 9.7 27.23 15 10.7 11.39 12.21 12.56 16.12 12.39 16.36 17.27 14.55 NA 14.81 8.74 NA 15.62 13.39 15.8 12.96 14.69 20.28 15.89 9.8 14.89 20 9.34 25.46 10.34 27.19 11.37 12.05 15.51 7.69 11.48 24.52 17.34 11.43 24.66 14.11 9.85 12.65 20.81 6.81 23.08 18.26 10.17 4.35 8.29 NA 13.81 17.74 20.34 15.79 21.21 21.88 10.29 19.51 16.1 13.2 10.64 13.79 23.79 10.79 16.39 12.92 16.46 15.61 23.69 14.29 14.71 25.63 10.92 0.000498 0.014373 N cassette FLT3 chr13 - chr13:28623675-28624231;chr13:28623599-28624231 chr13:28623599-28623771,chr13:28623675-28623771;chr13:28623912-28624231 chr13:28623772-28623911 100 100 98.82 96.53 100 95.58 90.45 100 95.95 98.74 100 100 100 100 100 97.44 93.65 98.15 97.96 100 100 100 100 98.75 100 100 100 98.15 96.11 100 100 100 100 100 100 84.51 100 97.89 100 89.05 95.61 100 98.81 100 100 97 97.72 100 97.48 100 100 92.9 95.32 98.47 93.86 97.81 100 100 100 100 98.27 100 96.36 100 96.88 100 98.08 100 100 100 98.52 100 100 99.14 100 100 100 98.79 100 100 94.34 100 100 97.14 100 95.79 100 100 98.05 96.65 100 79.23 100 100 97.39 100 100 100 100 100 97.45 98.09 98.24 100 100 98.45 99.07 97.13 97.5 100 97.76 100 95.51 100 NA 100 94.07 100 100 97.91 97.04 100 93.92 100 97.78 100 100 100 96.75 94.94 98.6 100 100 100 95.21 100 100 100 100 100 93.51 100 100 98.58 100 97.24 100 100 100 100 100 100 98.26 100 92.22 100 97.85 95.21 96.12 86.79 97.04 100 98.53 96.05 93.12 95.24 98.53 96.97 100 100 100 97.98 100 87.92 -12.08 0.0005 0.014373 K cassette FXR1 chr3 + chr3:180688147-180693909 chr3:180688147-180693100;chr3:180693193-180693909 chr3:180693101-180693192 39.7 31.43 36.17 33.57 35.03 27.18 17.91 33.06 23.86 33.17 50.68 47.69 33.06 38.03 37.05 48.57 30.53 37.1 32.43 42.67 29.91 40.7 33.14 40 47.28 25.81 34.38 31.17 43.1 39.08 29.25 29.19 36.55 24.11 39.94 50.5 42.61 38.17 31.52 50.25 21.43 39.05 24.6 40 34.68 50 26.56 40.67 33.82 38.94 33.33 46.51 31.43 37.33 31.54 19.66 27.34 49.52 35.25 36.43 38.84 34.97 36.9 34.2 35.17 35.71 42.48 27.2 32.32 55.81 25.71 30.36 41.58 28.11 29.94 35.61 26.36 33.12 34.81 26.13 30.54 26.13 35.23 31.74 26.9 41.58 30.59 34.85 25.95 28.57 51.22 53.57 33.65 32.26 27.59 33.33 34.78 12.8 32.45 41.51 31.95 39.22 32.2 31.06 25.85 26.11 33.14 27.91 40.31 32.08 25.51 40.87 42.34 39.02 41.94 31.29 27.9 23.18 35.48 41.3 29.8 33.16 20.48 24.68 33.85 27.5 30 36.54 26.61 53.95 44.58 31.22 36.71 37.86 43.48 39.18 43.12 41.1 42.52 40.43 38.1 35.78 44.92 32.81 36.99 29.77 27.64 39.18 38.89 36.16 25.99 37.14 25.32 35.48 31.01 35.85 33.33 26.83 41.1 51.97 24.2 28.81 39.47 33.7 34.38 29.66 38.14 21.99 34.16 36.31 36.54 27.59 33.85 51.23 17.38 0.00006 0.003373 K mutually_exclusive GALNT7 chr4 + chr4:174216995-174219265,chr4:174219449-174223197 chr4:174216995-174218945,chr4:174219129-174223197 chr4:174219266-174219448 chr4:174218946-174219128 40 45.68 40.5 43.66 40.35 NA 36.36 27.03 32.43 34.97 27.85 20 36.36 40.85 27.97 34.18 25.81 39.64 28.69 25 25 15.38 38.33 30.56 30 16 17.95 34.38 31.88 37.5 25.64 30.63 40 33.33 35.37 57.41 29.69 28.4 31.25 56.86 21.05 25.19 28.79 30.43 16.67 25.19 21.88 32.69 30.34 19.78 31.82 47.37 34.92 37.27 34.55 40.54 49.18 27.78 34.92 25.23 33.33 25.93 26.92 37 23.95 35.42 34.02 28.74 28.05 43.56 31.25 28.83 19.23 32.47 36.84 26.55 18.52 21.95 21.92 36.78 31.25 35.29 39.44 26.92 38.37 25.64 10 34.83 26.72 22.5 11.76 53.97 36.49 42.39 29.49 19.44 48.39 27.5 41.54 40 30.33 36.67 37.21 43.9 32.82 32.85 25.37 36.63 32.86 24.32 28.79 26.67 44.66 10.53 40 21.32 32 38.1 15.91 31.78 31.85 35.96 41.94 39.02 24.83 34.78 32.86 21.57 35.71 39.02 41.35 33.33 20.45 26.73 42.86 10 32 44.83 36.11 23.81 56 50.91 46.15 26.21 31.17 33.33 19.23 29.41 NA 10 NA NA 30.99 48.65 35.79 34.43 52.31 39.22 21.74 57.65 23.53 45 28.95 32.89 51.56 41.18 30.34 33.71 22.4 34.38 44.19 34.34 32.43 55.41 22.98 0.00008 0.008891 N cassette GATAD2A chr19 + chr19:19516829-19576148;chr19:19496948-19576153;chr19:19496948-19576148;chr19:19516829-19576153;chr19:19538802-19576148 chr19:19538802-19546939,chr19:19516829-19546939,chr19:19496948-19546939;chr19:19547029-19576153,chr19:19547029-19576148 chr19:19546940-19547028 NA 100 27.91 42.86 33.33 20.69 29.91 63.16 23.26 37.04 57.89 NA 24.32 NA 31.58 29.55 30.43 34.48 39.13 20 30.77 NA 61.11 32.79 40 15.09 35.71 40.35 47.37 40.91 43.9 35.48 NA 22.97 54.55 11.11 17.31 25.45 40.91 10.87 58.33 NA 30.43 46.15 25 13.89 38.71 29.11 33.33 19.15 18.75 18.6 33.33 31.58 12.24 22.22 61.9 34.69 38.64 26.79 29.51 51.52 33.33 20 26.09 23.08 29.63 33.33 39.22 20.31 23.53 20 21.57 15.79 20.93 33.33 58.82 52.94 15.15 41.18 30 35.29 25 40.74 46 11.11 37.04 23.81 33.96 43.33 NA 30.77 23.08 NA 20.41 100 15.15 21.05 20.29 25.6 29.41 31.82 33.33 28.89 24.64 24.07 26.09 21.18 31.37 17.39 20 18.18 27.08 20 18.92 20.45 32.43 26.67 57.14 31.37 38.46 35.9 38.89 22.81 33.33 18.63 52.38 NA 45.9 NA 37.04 56.52 42.86 52.63 50 36.59 45.45 47.06 21.74 NA 45.45 20 NA 21.43 21.88 35.85 30.77 44.44 NA 21.74 NA 47.37 28.57 27.03 18.75 58.33 43.9 51.52 24.32 15.15 43.48 13.04 37.93 31.82 30 41.18 28 20.93 21.88 31.82 45.71 37.14 31.82 16.88 -14.95 0.001691 0.03472 N cassette GCFC1 chr21 - chr21:34121010-34123429 chr21:34121010-34123227;chr21:34123344-34123429 chr21:34123228-34123343 82.54 100 91.96 100 100 100 100 100 93.75 100 89.19 100 84.62 83.33 100 91.67 91.43 100 85.42 100 88.89 100 100 91.67 93.98 100 100 100 80 84.75 83.84 100 100 100 100 74.07 90 87.97 89.74 80.28 90 100 83.02 100 100 85.96 100 88.18 82.35 85.71 83.33 84.09 100 100 100 100 100 94.02 88.89 88.89 100 85.71 89.61 100 93.83 100 85.71 87.5 80.95 84.07 100 92.54 87 100 85.15 87.01 93.67 100 82.95 100 100 100 89.58 100 92.19 100 100 93.81 92.63 88.51 100 86.57 100 100 100 100 100 93.2 92 100 89.36 89.69 100 93.83 100 91.57 84.8 91.21 100 100 81.32 100 100 100 90.91 91.84 89.6 83.49 100 90.2 81.93 86.51 100 95.8 84.55 100 85.48 82.22 100 100 90.54 100 100 100 100 100 100 86.67 100 100 100 100 100 87.5 100 85.56 100 100 100 100 NA 100 88.76 100 100 100 100 83.64 82.26 80.22 91.04 100 82.76 100 100 100 83.91 100 94.25 100 100 100 100 82.17 -17.83 0.00009 0.00453 N alternative_acceptor GLI4 chr8 + chr8:144351691-144356873;chr8:144351691-144354565 chr8:144351691-144356889 chr8:144354566-144356873;chr8:144356874-144356889 chr8:144356873-144356874;chr8:144356889-144356890 NA 0 0 0 NA 0 14.47 NA 0 0 0 NA 0 NA 0 0 0 0 0 NA 0 0 NA 0 0 NA NA 0 0 0 0 0 NA 0 0 14.29 0 0 0 12.7 0 0 0 0 0 0 0 16.67 0 0 0 5 0 15.79 0 0 NA 0 0 0 0 0 0 0 0 0 0 25.81 0 11.86 0 0 0 0 0 0 0 13.16 0 0 0 0 0 0 0 0 0 0 0 10.87 0 0 0 0 0 NA 0 0 0 0 7.79 0 0 0 0 0 7.06 13.46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.82 0 0 0 NA 0 0 0 NA 0 0 NA NA 0 0 NA NA 0 0 NA 0 0 0 0 NA 0 NA NA NA 0 0 0 0 0 NA 0 8.62 13.51 0 0 0 0 7.25 0 0 0 0 0 0 0 10.24 10.24 0 0.000048 K cassette GPBP1 chr5 + chr5:56531860-56542126 chr5:56531860-56532939;chr5:56533000-56542126 chr5:56532940-56532999 27.85 19.27 28.15 19.8 20.39 10 9.64 33.33 17.02 30.1 24 NA 17.65 16.82 46.3 69.23 23.53 27.59 32.98 26.67 20 14.63 27.59 33.33 31.08 27.45 26.36 27.69 25.32 23.61 22.22 22.31 0 32.5 17.27 38 28.12 21.55 26.26 32.26 23.4 36.28 20.29 22.79 30.36 40.87 23.38 36.78 36 40.7 49.11 41.3 27.12 25.4 26.83 32 28.75 21.57 28.26 20.65 20.83 45.45 21.67 27.71 33.33 14.08 29.47 31.43 26.32 28.43 16.3 45.56 44.09 17.98 16.24 22.89 17.39 36 23.68 23.53 38.71 22.22 18.92 25.49 34.57 15.15 31.94 34.29 32.94 26.05 8.82 66.04 25.64 37.97 14.4 30.36 23.36 14.93 20 55.56 46.67 20.93 22.45 24.24 25.24 29.01 35.16 29.51 20.45 22.67 29.49 41.98 23.86 54.55 39.52 36.36 24.18 27.36 25.35 20.54 32.69 21.69 18.48 21.48 33.33 25.35 29.51 27.78 28.75 23.86 29.45 26.58 21.15 33.33 30.43 15 21.74 28.36 44.44 19.05 18.03 30.65 13.91 23.53 35 22.99 18.6 31.58 13.64 12 22.39 14.74 33.73 14.67 30.77 27.87 29.58 34.69 39.05 42.11 28.21 30.12 36.49 35 20.41 25.53 31.52 22.22 31.63 35.56 24.44 20.73 26.29 39.65 13.36 0.002643 0.04794 N alternative_acceptor GPBP1 chr5 + chr5:56543043-56545235;chr5:56543043-56545283 chr5:56543043-56545280 chr5:56545236-56545280;chr5:56545281-56545283 chr5:56545280-56545281;chr5:56545283-56545284 14.56 0.83 8.53 24.14 16.51 1.75 11.3 10.81 1.75 0.88 0.98 1.19 8.06 0.88 12.2 1.92 1.28 13.49 0.96 1.96 1.92 1.12 1.2 14.04 17.14 0.85 14.95 13.04 6.33 1.56 7.27 1 1.35 15.94 8.97 25.49 7.61 6.12 7.61 22.97 1.96 0.89 1.45 8.87 1.14 10.71 10 17.81 0.94 5.56 14.15 44.07 8.62 15.7 1.47 13.41 18.06 9.68 1.3 10.39 1.47 10 1.39 11.11 15.29 8.33 5.94 15 1.22 14.29 5.81 9.38 9.8 1.14 19.83 1.33 1.56 1.41 1.14 11.76 13.56 1.18 8.45 1.82 7.69 0.75 1.61 5.45 8.74 9.42 2.78 30 1.33 10.13 6.09 1.49 0.83 9.21 0.85 17.5 11.76 9.33 5.88 1.1 11.63 3.39 5.36 5.71 14.77 1.54 3.51 9.4 8.06 3.85 5.59 1.01 7.14 6.56 2.22 4.9 10.78 6.54 6.67 12.61 0.97 1.12 2.13 1.37 14.77 1.12 7.36 0.97 5.43 1.43 1.67 1.39 1.16 15.38 1.37 15.09 1.96 1.09 1.06 13.33 1.2 7.03 2.33 8.14 2.63 1.39 0.98 10.64 10.53 15 12.07 1.43 1.27 19.05 1.04 24.36 1.49 0.99 1.2 5.71 14.93 1.79 6.19 6.25 6.74 8.86 9.23 1.28 5.88 24.92 19.04 0.000072 0.006217 K cassette GTF2I chr7 + chr7:74131271-74143123 chr7:74131271-74133197;chr7:74133261-74143123 chr7:74133198-74133260 13.85 24.14 40.77 31.95 33.33 43.18 66.27 36.4 23.91 32.47 33.17 3.77 43.33 33.8 33.09 33.06 29.91 39.83 32.34 20.75 29.68 24.53 33.59 27.96 19.11 26.71 25 44.52 24.46 29.81 35.16 32.39 30.26 34.82 42.93 43.51 26.7 32.76 31.43 50.25 38.36 48.37 29.49 38.26 48.86 23.84 28.57 29.32 30.95 37.4 26.16 41.29 29.01 28.7 25.73 29.66 44.97 36.36 35.25 27.87 46.12 34.88 37.27 35.63 40.49 36.6 31.02 30.74 30.24 55.22 34.92 35.66 31.4 38.98 21.05 32.69 35.16 36.43 30.25 27.5 44.23 43.23 24.1 38.17 34.34 22.99 37.5 35.86 37.09 40.74 25.93 45.83 44.16 38.73 26.18 20.41 28.8 32.92 33.56 38.89 28.31 35.12 28.83 33.33 38.1 34.58 31.76 28.46 31.91 27.84 17.58 29.08 28.14 39.87 31.78 28.26 25.12 28.57 42.16 33.79 32.11 32.97 20.9 36.76 26.52 27 23.72 40.46 20.87 35.86 37.31 35.5 34.46 36.17 35.29 36.54 31.89 35.34 40.91 26.47 35.66 31.76 28.37 34.3 34.46 20.83 37.65 30.39 35.48 31.52 28.97 16.09 34.8 36.57 36.77 32.54 40.95 35.19 34.4 49.48 34.22 36.54 25.99 31.14 30.72 23.97 36.88 35.56 35.35 34.05 40.98 32.59 32.97 47.66 14.69 0.000093 0.004592 N cassette GUSB chr7 - chr7:65439692-65441001 chr7:65439692-65439905;chr7:65440059-65441001 chr7:65439906-65440058 66.98 88.64 61.19 66 77.14 72.16 87.05 81.98 83.44 60 71.11 38.82 74.51 70.5 57.56 60 83.84 70 70.22 73.56 77.56 74.17 78.17 73.84 67.52 73.01 73.91 69.13 66.49 75.72 67.74 70.93 71.43 68.54 79.29 38.96 62.5 68.51 67.49 43.93 80.56 100 71.94 83.17 66.67 75 79.02 82.67 64.41 72.22 62.29 63.97 74.49 70.53 76.83 77.7 76.15 64.41 72.93 75.81 81.58 66.96 80.3 61.54 61.06 73.13 71.58 74.15 73.3 68.63 83.06 100 51.88 85.71 68.46 72.68 76.32 80.25 72.41 64.58 78.53 67.59 72.41 73.66 85.71 65.38 69.39 78.31 69.93 80.82 73.58 48.68 76.67 71.01 62.59 80.95 100 78.45 67.8 84.27 75.81 75.81 75.93 77.67 87.27 75 72.87 81.25 72.73 100 76.11 71.11 78 59.57 60.16 77.59 73.46 70.59 81.98 73.4 55 67.89 75.11 67.74 70.27 66.22 73.39 77.5 73.42 70 78.12 62.12 73.77 73.53 86.3 70.16 82.5 60.71 72.73 76.12 100 72.48 69.51 68.17 56.99 72.31 79.25 70.45 100 56.52 68.97 80.36 72.04 77.55 63.33 78.17 69.31 71.74 50.56 42.02 68.21 77.27 84.14 54.01 62.26 61.22 68.31 71.88 65.38 78.24 64.06 63.52 72.87 46.3 -26.57 0.000458 0.014065 N cassette H2AFY chr5 - chr5:134681748-134688635;chr5:134681748-134696186 chr5:134681748-134686512;chr5:134686604-134696186,chr5:134686604-134688635 chr5:134686513-134686603 35.42 21.7 13.46 23.06 17.97 25.22 38 12.73 30.45 22.12 19.02 18.79 19.97 25.61 9.97 14.48 23.5 24.25 16.4 18.92 25.96 31.69 20.33 18.3 32.58 21.56 21.8 20.38 28.12 40.58 17.39 15.75 14.24 19.94 36.38 7.09 19.78 22.84 18.44 11.7 24.76 20.8 29.01 23.05 22.69 23.65 21.18 14.29 16.67 33.17 13.64 7.43 16.29 13.37 21.06 24.87 15.35 27.46 16.17 15.16 19.41 33.04 39.13 16.97 18.53 13.33 23.16 17.28 18.08 14.36 18.29 15.59 24.7 21.91 31.34 20.65 18.06 16.41 26.79 19.47 29.53 33.73 32.74 25.47 17.18 13.78 17.67 24.64 15.89 27.15 29.97 8.17 15 11.57 17.51 30.14 26.52 16.02 18.04 17.05 22.86 39.43 22.83 26.03 23.61 15.88 17.28 19.18 41.55 27.9 27.94 22.38 20.58 24.03 25.64 21.91 18.62 25.81 17.88 14.78 15.4 19.58 41.29 24.94 14.43 20.59 16.55 20.97 41.34 19.79 21.68 17.62 15.68 21.56 32.2 18.22 16.01 32.34 14.29 24.92 15.53 18.6 35.52 22.92 11.11 37.4 28.5 29.26 9.73 32.17 13.04 39.01 20.75 21.75 19.59 32.67 18.67 23.75 22.4 11.65 13.55 23.39 15.99 23.97 16.89 26.65 14.53 20.12 15.79 25.51 20 24.75 20.75 9.91 -10.84 0.000078 0.004069 N cassette HDAC10 chr22 - chr22:50687181-50687531;chr22:50687181-50687756 chr22:50687181-50687259;chr22:50687289-50687756,chr22:50687289-50687531 chr22:50687260-50687288 100 100 100 100 100 85.71 88.74 100 100 100 86.05 100 100 100 100 68.33 88.37 100 100 100 100 100 100 100 85.56 100 100 91.95 100 100 100 100 100 95.5 100 79.41 100 100 100 66.67 100 100 89.86 100 100 100 84 88.64 100 100 100 90.77 88.1 84.38 100 91.38 100 100 100 100 100 100 100 100 100 87.04 87.72 89.66 100 87.3 100 100 100 100 100 89.36 86.49 100 100 100 100 100 100 82.76 100 100 100 85.71 90 100 100 100 100 100 88.46 100 NA 85.71 92.59 91.28 85.44 89.89 93.58 85.94 100 100 82.28 93.59 92.66 100 100 90 85.71 100 100 92.75 100 100 100 90 100 100 100 100 100 84.91 100 100 89.36 100 85.29 100 100 100 100 100 100 100 100 100 100 100 100 90.58 100 100 100 83.33 100 83.33 100 100 100 89.06 100 100 100 88.89 100 88 100 100 100 100 100 86.42 88.89 100 100 84.78 100 87.18 100 87.65 -12.35 0.002124 0.041069 N alternative_acceptor HERC1 chr15 - chr15:63967293-63970043 chr15:63967317-63970043 chr15:63967293-63967316 chr15:63967292-63967293 NA 26.67 15.22 50 NA NA NA 0 33.33 17.65 21.95 NA 17.95 13.64 0 16.67 26.92 31.25 35.48 0 12 0 15.62 26.47 0 16.67 6.67 17.86 10.64 7.69 27.27 22.22 0 NA 0 65.38 NA 18.92 27.91 52.38 16.67 27.91 23.08 10 33.33 27.03 NA 24.56 25.93 17.07 13.33 63.16 NA 17.65 27.78 10 14.29 22.86 31.25 22.22 24.07 NA 7.69 21.43 15.79 20 20 23.08 15.62 34.29 16.67 14.86 10.34 25.49 23.33 16.28 24.39 16.13 20 18.75 36.36 35.71 26.09 12 24.32 23.53 15.79 20 21.21 18.18 17.5 54.55 26.47 19.15 25 28.89 25 20 25.58 27.78 16.67 22.58 35.71 50 37.93 30 33.33 18.37 22.58 43.48 13.33 22.22 24.64 NA 27.91 26.47 16.13 23.7 0 31.58 26.92 NA 29.41 27.27 23.4 13.89 25 28.57 24.39 33.96 9.68 42.11 22.73 20 28.57 NA 21.21 32.14 22.22 11.11 NA 20.59 10.81 18 22.22 17.07 40 25.71 NA 35.48 NA 11.76 26.47 23.08 9.52 32.5 21.43 21.43 25.42 43.33 46.15 0 20.51 20.83 52.17 NA 6.82 35.29 24.24 11.43 40.91 13.64 22.22 53.47 31.25 0.000078 0.00666 K cassette HIATL1 chr9 + chr9:97216353-97220603 chr9:97216353-97218521;chr9:97218620-97220603 chr9:97218522-97218619 100 91.11 84.62 100 100 NA 100 81.08 90.3 100 100 100 100 91.78 100 87.18 86.67 100 100 100 91.75 100 82.61 87.93 100 100 86.75 91.82 90.77 100 85.9 100 100 85.25 100 80.49 80.3 83.7 93.18 90.91 85.71 100 90.14 100 100 100 100 84.09 100 100 91.46 81.93 84.38 91.11 100 89.66 100 100 88.89 93.97 89.55 100 93.48 100 100 83.33 100 88.52 100 88.57 88.37 90 100 92.19 89.62 88.42 100 87.5 89.36 100 100 93.62 86.76 100 100 100 100 100 100 92.24 100 77.08 100 100 87.64 90.57 100 92.59 100 100 87.38 93.33 100 100 100 100 92.31 100 91.51 100 100 86.67 100 100 100 88.16 89.33 92.11 100 100 100 93.15 89.47 100 90.28 100 85.19 100 93.57 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.18 100 100 100 100 NA 100 90.28 100 100 87 100 85.92 93.06 86.73 88.73 100 93.06 100 100 91.67 100 100 93.24 88.89 79.41 88.37 100 84.33 -15.67 0.000232 0.009149 N cassette HLA-F chr6 + chr6:29693341-29694659;chr6:29693341-29705898 chr6:29693341-29693787;chr6:29693821-29705898,chr6:29693821-29694659 chr6:29693788-29693820 100 100 NA 100 NA 100 100 NA 100 100 100 100 65.71 100 100 100 86.67 100 100 100 100 100 100 100 100 100 100 100 100 100 89.83 NA NA 100 100 70 NA 100 100 85.11 87.76 100 100 100 100 100 84.38 100 90.74 100 100 80 100 77.27 100 100 100 89.13 100 100 100 100 92.42 100 100 NA NA 100 100 50.53 100 83.64 100 80 100 100 100 84.85 100 100 100 85.96 100 100 NA NA 100 100 100 88.52 100 NA NA 100 100 100 100 100 100 100 100 100 100 88.55 76.92 55 100 100 100 100 100 100 89.23 100 100 NA 100 100 100 100 100 100 100 87.32 100 92.21 100 NA 100 100 NA NA 100 100 100 100 100 89.71 NA 86.84 100 NA 100 100 100 94.44 100 100 NA 100 100 100 83.33 100 69.57 83.61 NA 100 100 63.89 100 100 100 100 100 100 100 100 100 NA NA 100 100 70 -30 0 0.000038 K cassette HMGCR chr5 + chr5:74650523-74651189 chr5:74650523-74650880;chr5:74651040-74651189 chr5:74650881-74651039 NA 69.09 78.95 28.57 100 NA 40.74 77.27 50 100 100 NA 72.41 69.23 63.41 100 57.14 NA 70.77 100 61.54 NA 100 79.31 73.68 100 100 46.67 67.44 84.85 70.37 65.79 100 85.37 100 37.5 69.7 63.33 71.05 47.92 52.63 68.97 58.54 84.21 NA 85.19 74.19 79.17 75 84 74.36 46.43 100 63.04 75 79.49 42.11 100 80.65 68.63 72 40 NA 74.19 69.23 65.52 78.79 58.33 72.73 63.64 71.43 81.25 100 70.27 65 84.21 61.11 72.22 73.33 72.5 NA 72 58.82 57.14 87.27 82.76 100 NA 70.37 82.35 NA 52.94 100 100 62.79 51.85 67.86 75.86 100 NA 69.05 62.79 67.86 100 58.59 77.55 71.43 81.48 56 70.37 78 100 51.72 NA 100 76.92 73.47 80 64.52 100 70.59 51.52 60.47 56 81.82 75.41 58.82 100 61.76 NA 82.61 100 100 100 100 100 100 NA 100 100 NA 66.67 34.78 64.29 54.84 58.54 NA 65.62 NA 100 NA NA 100 57.89 60.87 83.87 58.06 57.58 69.44 56.41 80.56 47.06 74.36 53.57 44.44 67.86 100 78.12 63.33 71.43 42.11 100 72.5 50.43 -22.07 0.000941 0.022337 N cassette HNRNPM chr19 + chr19:8539129-8550486 chr19:8539129-8548041;chr19:8548096-8550486 chr19:8548042-8548095 91.43 87.36 90.04 88.46 87.39 86.74 91.73 82.76 79.22 81.75 89.33 100 87.86 85.64 80.64 88.57 72.58 87.32 79.58 83.21 82.88 88.41 87.44 85.34 85.86 82.2 86.84 80.63 77.05 88 83.12 88.11 79.44 75.64 87.23 71.22 82.16 88.7 85.56 70.18 82.61 90.09 88.52 88.24 92.92 81.86 83.54 83.41 82.02 84.51 77.63 71.84 76.09 93.1 83.85 83.87 88.82 87.79 81.58 82.35 84.05 81.98 88.1 93.59 80.19 83.13 82.09 86.53 88.89 79.14 77.78 83.82 82.01 83.33 90.08 78.6 79.31 81.69 87.5 86.55 85.53 87.74 78.16 82.47 75.78 80.62 100 88.5 89.27 85.14 100 75.78 87.1 100 77.36 88.64 91.45 79.37 84.65 84.02 87.26 79.72 82.78 82.54 88.06 88.84 90.62 73.68 83.04 86.72 77.18 84.62 80.58 81.4 88.69 89.44 78.22 84.14 86.46 82.93 88.93 87.44 85.12 90.53 81.28 82.08 82.05 90.28 86.22 87.36 91.17 83.08 84.54 100 85.51 79.89 87.37 86.25 78.62 83.96 89.44 87.58 100 86.35 80 85.62 85.87 82.72 100 76.92 82.56 85.38 88.73 90.16 81.61 83.04 87.16 77.69 81.85 70.29 77.55 87.22 81.82 88.11 84.57 83.92 82.98 85.43 84.75 84.83 74.4 77.39 84.83 71.53 -13.3 0.000074 0.003954 K cassette HPS1 chr10 - chr10:100193849-100195391 chr10:100193849-100195028;chr10:100195172-100195391 chr10:100195029-100195171 65.12 82.65 90 85.53 86.67 90.57 69.58 88.3 87.62 82.26 82.3 100 88.1 95.41 82.8 55.46 78.64 71.43 73.1 86.11 83.33 100 77.78 87.7 88.61 87.43 83.7 87.67 89.66 83.78 84.95 87.85 82.46 86.45 100 66.15 69.33 82.01 84.87 60.34 76.92 84.62 79.62 85.58 89.52 66.67 81.6 85.77 88.97 91.18 55 85.85 81.82 90.27 72.73 87.9 100 87.5 85.62 82.8 93.83 93.33 90.64 64.49 74.14 89.01 90.98 72 79.84 70.64 88.1 72.22 76.52 90.97 75.85 83.8 93.81 91.11 85.93 72.58 73.21 89.15 82.61 94.35 75.68 82.67 52.31 82.72 70.29 93.68 80.77 60.78 63.24 84 81.78 84.48 75 84.34 83.63 79.85 83.25 91.03 83.47 88.57 91.18 73.73 86.26 90.73 76.56 81.4 82.97 69.08 90.86 80.65 86.44 83.08 75.16 88.11 79.28 83.61 75 86.41 94.5 83.75 88.54 78.3 84.43 100 82.99 75 81.25 92.05 84.38 85.33 86.46 84.87 75.49 79.71 91.41 86.3 90.29 87.18 72.6 84.77 94.25 77.49 84.06 65.38 78.05 81.95 100 84.62 88.89 84 92.71 84.78 86.24 82.91 74.81 58.33 80.43 79.22 69.41 73.33 70.27 83.85 87.9 70.43 86.11 85.43 65.22 83.02 84 63.47 -20.53 0.002578 0.046973 K alternative_acceptor IBTK chr6 - chr6:82906119-82909857 chr6:82906164-82909857 chr6:82906119-82906163 chr6:82906118-82906119 100 100 93.26 100 100 NA NA 100 100 100 100 NA 80.65 100 100 100 100 100 87.5 100 100 100 100 100 100 100 100 100 100 84.91 100 100 100 100 100 72.73 100 91.38 100 80 100 100 100 100 100 100 100 100 100 100 100 78.38 100 82.56 100 100 100 100 100 100 100 100 86.84 100 100 100 100 100 100 87.04 100 100 100 100 100 89.58 80.77 100 100 86.67 63.64 100 100 100 85.71 100 100 83.33 83.72 100 100 100 100 100 100 100 100 100 100 100 89.19 87.5 100 100 83.33 100 100 88.68 100 100 100 100 100 100 100 100 100 85.26 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 88.37 100 79.17 100 100 80.77 100 83.64 100 100 100 100 100 100 100 100 100 100 100 100 100 81.82 -18.18 0.000001 0.000162 K coord_cassette IFI16 chr1 + chr1:159002482-159021468 chr1:159002482-159015086;chr1:159015255-159019221;chr1:159019390-159021468 chr1:159015087-159015254;chr1:159019222-159019389 100 74.27 81.73 90 76.11 100 94.16 100 66.09 70.5 82.86 100 82.35 84.34 70.04 82.69 71.92 83.86 71.17 100 76.92 72.13 72 93.79 79.41 81.14 72.22 81.48 74.75 80.77 81.25 81.82 100 82.73 84.4 68.59 73.21 82.59 84.19 74.24 80 82.44 82.81 71.83 84.21 49.06 76.99 87.8 80.7 90.97 68.63 61.11 89.16 81.71 75.68 87.84 100 84.62 84.96 80.68 83.81 80 87.3 85.51 94.71 100 82.76 78.84 83.18 76.81 87.26 81.55 72.5 90.33 84.56 87.58 85.47 73.09 86.3 83.56 100 91.01 72.97 86.82 83.05 22.73 86.58 76.69 87.43 76.26 100 68.25 77.53 69.71 77.57 78.91 84 69.8 88.31 81.51 81.53 89.39 79.51 91.22 85.78 74.41 76.85 82.14 87.39 87.68 80.21 75.69 90.32 84.75 79.63 83.97 56.52 77.27 80.1 91.46 77.05 77.98 88.78 90.21 73.33 79.27 67.89 78.41 71.6 85.85 80.49 72.5 79.12 82.63 77.46 100 91.14 94.25 82.19 78.38 79.41 81.9 80.95 84.06 76.19 82.25 85.71 88.95 100 71.88 100 62.64 81.76 78.26 86.09 83 85.71 86.96 88.51 65.43 83.82 82.95 70.15 81.37 92.31 87.69 89.8 80.18 76.02 75.56 79.31 81.43 82.19 68.42 -13.77 0.000519 0.015348 K cassette IKBKE chr1 + chr1:206644589-206647673 chr1:206644589-206646538;chr1:206646658-206647673 chr1:206646539-206646657 100 100 100 NA 100 100 90.16 100 91.67 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 87.69 100 100 100 100 86.96 100 78.95 100 100 100 100 79.41 100 100 100 75.68 100 NA 83.33 100 100 100 100 100 100 100 88.24 81.82 100 90.57 100 100 100 100 100 100 100 100 100 88.24 92.75 100 88.64 86.84 100 83.72 100 86.67 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92.06 100 100 100 100 100 100 NA 100 100 95 100 100 84.48 100 100 100 100 93.33 100 100 100 77.05 100 100 100 80 100 NA 100 100 100 100 91.89 100 100 89.58 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 83.33 100 NA 100 100 100 100 100 100 100 87.5 100 100 78.95 100 100 100 100 100 100 100 90.57 100 100 83.33 100 100 80.61 -19.39 0.000001 0.000108 K cassette IL18 chr11 - chr11:112020930-112025697 chr11:112020930-112024314;chr11:112024327-112025697 chr11:112024315-112024326 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.42 100 100 91.72 100 100 100 100 95.58 100 100 100 100 100 100 100 100 92.86 100 100 82.72 100 96.54 100 100 100 NA 100 100 100 100 96.3 100 100 100 100 83.33 92.65 100 88.52 100 94.52 100 100 100 100 NA 100 100 93.26 100 89.13 100 100 94.35 97.22 100 100 100 100 100 100 83.16 100 95.83 96.23 100 100 97.45 100 100 100 100 97.42 100 100 81.43 100 100 96 100 100 78.41 100 100 96.85 100 100 100 100 100 96.2 100 100 100 92.24 100 100 100 100 100 95.93 100 100 100 100 100 95.62 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92.5 94.95 100 100 100 100 100 100 100 100 93.33 100 100 100 100 74.51 94.86 100 97.41 100 91.03 78.86 100 100 97.45 100 100 96.7 100 83.03 -16.97 0.000022 0.001357 K alternative_acceptor IMMT chr2 - chr2:86398433-86400772;chr2:86398436-86400772 chr2:86398469-86400772 chr2:86398433-86398435;chr2:86398436-86398468 chr2:86398432-86398433;chr2:86398435-86398436 36.11 29.87 28.57 51.16 43.14 54.55 43.1 30.26 26.39 38.78 36.62 100 45.45 25.45 33.04 25 21.74 30.51 27.55 36 26.56 30.3 40.62 24.56 30 32.29 45 32.81 33.93 26.09 36.96 37.31 NA 46.67 36.36 26.19 29.03 39.8 35.59 16.9 45 28.57 31.58 29.87 39.73 23.81 31.34 26.98 39.66 23.68 32.67 20.24 34.69 30.95 30.19 23.81 51.52 25.4 34.21 27.71 42.47 40 42.37 29.51 28.92 31.11 32.2 31.03 30.3 30.49 40.54 27.59 32.39 44.44 31.03 28.57 29.17 36.84 23.81 28.21 43.75 38.71 34.69 32.65 29.51 34.62 45.65 44.9 32.1 30.17 21.88 19.7 26.87 38.46 32.93 44.44 35.42 36.54 33.33 32.56 24.24 33.67 34.12 31.82 46.15 52.7 24.77 30.11 30.21 34.78 29.23 47.83 34.25 28.12 37.18 33.85 29.31 25.17 34.48 33.33 51.9 36.99 30 37.04 34.18 40 25 42.31 36.15 33.93 23.01 37.17 31.48 38.24 27.66 31.15 46.55 37.74 37.59 44 32.65 31.51 30.59 33.33 31.65 32.86 33.33 39.62 60 36 25 41.67 31.88 31.43 31.91 51.11 45 45.71 32.39 21.67 38.03 41.18 39.47 39.62 30.51 26.32 34.74 36.67 33.94 34.48 59.26 38.78 33.76 20.95 -12.81 0.000294 0.019947 K cassette INTS3 chr1 + chr1:153733395-153734045 chr1:153733395-153733495;chr1:153733586-153734045 chr1:153733496-153733585 16.28 18.05 11.76 26.74 13.4 18.18 15.85 5.8 12.38 19.1 18.28 6.67 13.11 15.24 8.43 7.02 16.13 10 13.51 4.65 6.86 10.34 12.09 13.39 11.27 3.85 8.11 9.73 12.39 11.76 12.05 14.08 1.92 14.58 12.09 28.77 9.35 17.02 10.74 19.08 10.45 31.82 9.88 16.06 4.76 13.98 10.1 10.74 11.43 18.45 14.29 26.61 15.49 10.64 24.39 19.12 6.67 22.08 17.28 8.4 13.48 22.81 5.56 7.59 14.39 9.46 6.29 12 9.24 19.49 15.46 8.21 18.05 12.85 20 13.16 10.87 10.26 12.82 13.33 9.3 15.19 9.09 11.36 11.59 14.08 18.18 20.88 16.81 6.33 12 16.98 10.17 10 11.85 8.82 38.46 6.87 15.25 12.59 14.69 14.71 16 11.65 8.67 17.09 16.96 14.36 13.51 13.79 12.14 8.57 10.69 4.08 14.29 25 17.24 21.3 19.61 17.27 8.53 13.33 19.05 13.64 16.3 13.93 10.98 20.51 3.8 23.73 19.47 7.69 7.27 30.91 8.16 4.76 9.68 14.93 7.78 24.56 16.67 16.28 21.92 10.69 10.71 14.55 13.89 15.25 NA 14.06 10 5.08 16.19 18.18 8.24 18.28 14.86 18.52 18.8 26.09 10.81 15.12 5.5 7.27 9.09 18.18 11.19 8.11 10.53 11.9 10.61 5.88 12.71 22.79 10.08 0.000547 0.015152 N cassette IQCB1 chr3 - chr3:121545028-121547707 chr3:121545028-121547316;chr3:121547480-121547707 chr3:121547317-121547479 100 92.65 95.9 100 100 81.48 90.32 100 91.38 100 90.62 100 87.8 100 100 100 87.34 100 90 100 100 100 100 100 100 100 100 100 100 88.37 88.57 100 100 77.59 100 82.14 100 92 100 85.11 100 100 100 94.95 100 88.89 83.78 87.5 100 100 100 77.78 100 100 86.27 100 100 100 91.67 84.85 100 90.57 90 100 84.52 82.46 92.96 100 88.71 89.06 81.63 100 88 88.73 87.1 100 100 100 100 89.53 100 89.8 100 87.23 100 100 100 92.19 91.95 87.88 100 68.89 100 91.89 100 100 84.21 87.78 93.83 100 100 100 100 83.67 91.23 85.71 87.13 81.01 100 100 100 90.62 100 100 100 92 86.79 100 84 91.67 92.86 100 100 93.4 87.95 100 82.22 100 88.68 100 92.45 100 80 100 100 100 92.75 100 92.42 100 100 100 100 89.66 100 100 100 100 NA 100 NA 100 94.68 100 100 100 87.14 100 89.04 75.41 87.3 100 91.3 88.89 100 100 90.91 100 100 90.62 100 100 100 79.96 -20.04 0.000047 0.002704 K alternative_acceptor IRF5 chr7 + chr7:128587111-128587331 chr7:128587111-128587283 chr7:128587284-128587331 chr7:128587331-128587332 58.33 45.45 30.16 55.56 37.78 23.53 38.16 31.43 44.52 54.39 45.45 30.38 44.44 51.43 47.62 54.05 45.45 55.29 62.96 17.74 43.9 41.18 43.08 22.34 28.32 48.65 55.41 30.3 48.15 37.5 46.15 32.2 42.31 60 44.9 27.78 44.12 46.34 51.9 13.79 100 66.67 42.77 60 51.56 52.17 40.25 34.21 34.57 38.04 42.86 20.45 38.89 37.14 48.86 28.35 37.5 57.89 65 43.75 50.79 NA 48.51 34.21 43.86 52.38 51.43 44.68 49.09 40 53.93 43.4 45.45 43.75 46.27 38.36 43.33 44.7 71.15 43.48 NA 62.75 47.06 36.46 54.29 55.17 43.48 47.54 43.42 48.17 57.38 19.61 35.29 55.56 59.26 46.81 50 39.81 39.51 54.44 40.26 34.81 48 37.68 36.67 29.82 44.77 38.95 31.72 36.36 42.47 48.94 60 54.05 50 50 43.1 NA 35 69.23 42.11 37 44.04 41.67 65.22 39.38 50 37.04 26.28 70 62.12 68.18 39.68 65.12 43.48 39.29 40.74 30.77 52.94 51.28 43.75 44.44 31.58 55.05 NA 36.6 NA 48.15 60 39.05 28.57 37.65 37.66 20.69 58.33 47.44 48.89 29.17 72.22 27.72 26.67 NA 33.55 31.25 57.14 36.52 38.46 34.78 38.66 51.85 45 NA 44.28 24.09 -20.2 0.000395 0.02457 K cassette ITGB3BP chr1 - chr1:63912528-63919588 chr1:63912528-63913235;chr1:63913286-63919588 chr1:63913236-63913285 0 47.62 7.69 50 22.58 38.1 46.88 18.75 19.05 8.82 30.77 NA 14.29 15.79 8.57 NA 41.67 10.34 0 0 11.76 21.74 0 28.57 30 0 0 53.33 0 NA 22.22 9.09 0 0 32.14 45.45 20 21.43 5.88 53.33 15.38 12.5 0 20 0 33.33 20.83 40.62 10 43.75 24.24 44 12.9 17.24 28.57 16.67 0 57.14 21.05 0 13.33 41.67 21.74 10 13.33 13.33 11.11 30 11.43 33.33 10 27.78 9.52 10.71 21.43 5.88 0 35.71 0 11.11 NA 0 NA 47.37 23.81 6.67 0 60.87 24.24 32.43 NA 50 14.29 13.04 0 NA 16.67 0 9.68 36.36 33.33 13.79 26.47 31.43 20 41.67 28.89 21.74 36 NA 17.65 13.04 23.08 NA 30.77 NA 19.51 17.86 0 67.74 41.67 24.39 36 16.9 10 53.33 0 NA 36 NA 22.45 0 0 0 0 0 0 0 12 NA NA 25.53 NA 22.73 20.93 36.36 13.33 10.53 0 NA 0 NA 18.42 16.67 25.93 NA 17.65 16.67 37.04 57.89 13.51 0 26.09 10 44.44 34.48 17.86 24 26.79 NA 13.64 26.09 16.9 47.73 30.83 0.000277 0.010378 K cassette JMJD1C chr10 - chr10:64977092-65024410 chr10:64977092-64979637;chr10:64979744-65024410 chr10:64979638-64979743 NA 59.76 67.65 60.4 59.38 NA 26.67 61.43 51.04 46.9 46.67 100 61.02 65.45 60.56 71.13 63.53 72.73 68.89 100 56 35.29 54.29 64.15 40 100 63.83 56.52 57.89 52.87 65.75 57.53 100 100 55.56 45.16 59.32 63.27 58.62 39.47 47.37 46.67 43.96 72.97 100 55.56 NA 54.55 52.94 57.83 54.81 48.33 NA 56.52 57.14 76 61.9 43.55 53.49 66.22 61.11 62.79 53.26 61.19 66.67 68.57 63.16 48.65 41.89 40.35 60.78 62.22 58.33 61.11 51.19 60 51.47 65.45 58.49 58.93 56 55.56 51.92 38.46 61.17 100 57.89 54.79 62.83 100 54.95 41.45 52.31 61.03 64.56 53.42 57.89 40.68 76.74 54.22 57.5 62.96 NA 67.74 64.13 64.79 61.7 52.05 60 59.14 50.75 60.42 60.18 56.1 48.39 53.85 48.48 66.67 52.73 65.18 51.02 51.85 57.69 52.59 57.14 51.28 57.69 53.47 59.24 58.43 72.34 66.67 50 55.26 51.39 100 61.22 66.67 72.29 67.65 53.45 52.7 44.44 66.67 51.52 46.85 56 64 55 43.18 NA 59.65 52.05 61.54 46.81 70.59 62 45.65 51.43 36.14 61.76 29.17 43.9 55.26 58.75 63.16 53.85 66.67 61.11 52.38 70.27 65.38 58.49 40.9 -17.59 0.000194 0.007959 K alternative_acceptor JMJD1C chr10 - chr10:64975378-64976966 chr10:64975457-64976966 chr10:64975378-64975456 chr10:64975377-64975378 NA 100 94.89 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 86.27 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.32 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 83.33 100 94.63 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.02 100 93.06 100 100 100 100 100 100 100 93.67 100 100 100 100 100 97.6 100 100 100 100 100 100 100 100 94.05 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 71.74 90.57 100 100 100 100 100 100 100 100 100 100 100 100 88.29 -11.71 0 0.000001 K cassette KARS chr16 - chr16:75675622-75681475 chr16:75675622-75678180;chr16:75678361-75681475 chr16:75678181-75678360 25.93 25 47.37 26.15 40.91 30 44.83 32.79 100 61.7 20 NA 48.84 32.5 38.37 32.61 59.42 31.31 31.08 50 47.92 40.62 31.37 41.67 46.67 14.85 45.83 40.91 39.22 41.94 46.67 38.16 35 30 33.33 20.59 52.17 36.71 37.14 29.17 47.62 37.5 41.86 36.51 20.69 37.5 39.44 53.45 48.39 34.43 54.29 28.95 56.41 38.1 30 26.15 44.68 57.14 32.26 42.42 37.1 57.14 27.91 39.13 44.05 41.18 43.18 32.86 31.51 27.42 18.46 48.15 39.44 39.08 36.84 47.76 47.83 49.18 59.57 35.11 65.52 42.55 54.55 33.33 35.29 28.21 54 58.93 42.39 32.1 41.94 13.33 38.89 33.33 35.85 26.67 24.39 54.55 47.22 53.06 47.44 46.94 29.33 35 55.56 31.82 35.94 33.82 31.15 23.81 27.78 30 32.2 37.5 44.3 38.89 57.78 43.04 24.53 61.54 42.5 44.44 27.78 52.11 50 52.5 34.62 45.16 22.78 32.35 27.71 38.55 36.23 44.44 35.71 28.38 31.25 10.91 30.56 25 26.83 37.5 24.39 44.79 47.73 43.75 41.38 25.35 NA 50 35 54.29 45.16 31.25 51.72 46.34 33.33 42.11 29.76 18.75 44.9 41.38 35.23 53.85 37.25 42.37 62.69 50 47.87 42.11 42.11 48.15 39.22 24.01 -15.21 0.000459 0.014065 K cassette KDM4B chr19 + chr19:5110830-5119663 chr19:5110830-5119128;chr19:5119231-5119663 chr19:5119129-5119230 NA 50 57.69 57.58 100 64.29 18.52 37.5 56 53.62 100 NA 41.38 61.54 81.63 37.5 26.47 40.91 41.18 100 34 15.38 40.62 22.58 27.03 100 40 29.79 45.45 46.67 34.48 41.86 60 50 37.5 21.05 59.38 51.61 54.55 26.32 50 100 35.71 50 100 46.51 43.33 70 39.56 39.29 70.59 11.76 57.69 47.06 59.26 36.84 50 52.17 50 43.75 63.16 33.33 37.04 28.57 55.05 63.16 57.14 36.67 40.74 16.28 31.67 35.14 35.82 48.65 42.5 48.28 34.62 13.33 48.39 57.69 58.33 36.11 45 28.21 48.57 80.65 31.03 54.29 41.43 33.33 40 47.06 53.85 47.06 31.71 55.56 100 48.15 44.68 29.09 37.21 44.44 44.12 33.33 43.75 34.21 36.59 48.94 40 42.31 51.85 45.95 37.04 42.22 62.39 36.76 43.48 69.57 48.15 46.15 31.03 28 39.53 47.62 51.55 37.04 52.94 64.29 33.33 50 77.42 43.75 64.29 21.43 55.88 100 100 44.44 72 100 100 53.33 100 28.57 100 35.29 46.15 69.7 NA 42.11 36.36 36.36 47.37 56.67 68 45 69.7 35.29 35.48 28.57 44 40.74 27.27 44.12 46.88 52.94 56.67 35.9 53.12 46.15 67.74 56.52 46.59 23.69 -22.91 0.001134 0.025641 K cassette KDM6A chrX + chrX:44918712-44920568;chrX:44918712-44919853 chrX:44918712-44919266;chrX:44919402-44919853,chrX:44919402-44920568 chrX:44919267-44919401 NA 75 63.04 20.48 100 15 0 38.24 50.94 72.5 100 NA 33.33 67.74 100 69.44 38.78 46.67 52.31 71.43 48.57 70.37 51.61 46.67 53.85 NA 100 27.59 60.71 53.52 54.24 52.83 NA 48.15 48.39 37.04 57.69 62.03 42.47 46.88 31.03 57.14 58.62 62.5 NA 57.78 NA 59.68 60.53 43.18 69.84 23.91 60 29.41 50 56.25 24.62 48.57 68.97 68.29 42.5 20 28.21 35.9 60.61 40.43 60.61 48.15 60 28.43 48.44 55.56 65.31 42.86 50 60 24 37.93 58.9 52.94 15.71 58.06 50.75 24.14 59.46 100 100 54.05 33.33 75 62.75 18.92 38.46 53.85 38.04 47.83 25 51.85 74.19 52.63 72.22 57.45 73.68 33.33 37.76 61.9 68.75 75 40.74 35.71 78.26 54.84 38.94 100 50 53.19 80 44.59 43.9 71.43 52 40.98 54.1 25.53 NA 72.73 65.31 50 52.38 33.33 100 41.86 100 37.5 79.17 100 44.83 25 52.63 29.17 46.67 54.29 24.14 51.56 55.56 54.93 42.86 70.37 35 100 NA 38.1 55.56 72 14.63 61.06 72.88 25.93 48.39 27.87 41.33 56.52 58.7 39.13 15 NA 60.47 52.94 48.48 62.5 40 32 52.73 28.15 -24.58 0.002718 0.048805 N alternative_acceptor KIAA0182 chr16 + chr16:85696700-85696991 chr16:85696700-85696949 chr16:85696950-85696991 chr16:85696991-85696992 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.62 100 100 100 100 100 100 84.31 100 100 100 81.6 100 100 100 100 100 100 100 100 100 100 100 91.43 100 100 100 100 100 100 100 100 100 100 100 91.95 100 100 100 100 100 100 100 100 100 91.14 100 100 100 100 100 100 100 90.91 100 100 100 100 100 100 93.42 100 100 100 100 100 100 100 100 93.18 91.87 100 100 100 100 100 100 100 95.05 93.08 100 100 92.19 100 100 100 100 100 94.16 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 97.25 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 85.15 100 100 100 100 100 100 100 100 96.05 94.23 100 100 100 88.29 -11.71 0.000001 0.000141 N cassette KIAA0319L chr1 - chr1:35944814-36019950 chr1:35944814-35972212;chr1:35972737-36019950 chr1:35972213-35972736 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 94.79 100 100 100 94.85 100 100 94.95 100 100 100 100 95.05 100 100 100 80.82 100 100 100 100 100 100 83.61 100 100 100 100 100 100 100 94.59 100 100 100 89.39 100 100 100 100 100 100 100 92.93 94.44 92.5 100 100 95.5 100 100 94.25 100 89.25 94.64 100 95.19 100 100 100 100 100 100 100 91.55 100 100 100 100 100 100 100 92.59 100 100 78.72 100 100 100 100 100 100 100 93.26 100 100 100 100 100 100 100 100 96.32 100 100 100 100 100 100 100 100 93.44 100 100 100 95.1 93.29 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 78.08 100 100 100 93.48 100 95.45 100 93.51 100 100 100 100 100 90.67 100 95 100 100 88.89 88.3 100 100 100 100 100 100 100 100 92.62 100 100 100 100 88.78 -11.22 0.000002 0.000182 N cassette KIAA0393 chr15 - chr15:23283154-23285704;chr15:23283417-23285704 chr15:23283417-23285445,chr15:23283154-23285445;chr15:23285601-23285704 chr15:23285446-23285600 7.69 23.26 24.56 20 15.64 9.8 15.79 18.07 25.41 24.11 22.68 10.49 22.4 16.75 14.78 21.97 39.47 18.29 39.75 9.3 17.28 9.52 34.29 56.38 18.04 NA 19.82 22.08 24.11 24.62 17.62 23.13 44.68 35.83 18.6 50 22.18 21.89 27.03 34.04 22.12 16.47 23.93 9.86 18.36 25.93 18.66 20.69 24.26 18.38 22.11 39.78 27.38 17.91 22.43 31.72 42.86 18.15 34.22 20.77 31.31 41.82 23.08 24.34 30.52 16.38 26.32 33.33 28.33 39.17 34.21 16.22 26.11 20.1 21.74 27.91 27.54 28.09 23.64 30.35 31.17 27.67 31.97 24.14 28.4 19.57 26.92 20.3 33.7 16.6 14.29 28.57 16.9 18.75 19.44 19.05 15.58 30.19 17.18 24.12 19.8 22.15 17.32 22.15 29.91 27.69 25.37 19.97 17.97 20.83 24.27 15.93 29.2 33.33 29.47 24.58 21.48 29.23 27.5 24.71 33.84 22.45 19.47 23.19 25.87 21.05 31.63 21.21 18.08 23.33 12.71 37.04 13.64 26.43 35 22.5 27.52 19.78 23.42 10.34 26.32 16.67 15.19 38.52 22.95 16.43 30.77 23.31 14.86 11.43 12.2 26.09 26.39 15.52 42.62 23.49 33.12 42.03 32.16 50.7 38.46 19.63 31.51 23.58 23.16 21.47 27.47 29.44 25.06 38.96 27.21 24.75 23.18 39.48 16.3 0.000359 0.01239 K cassette KIAA0494 chr1 - chr1:47152543-47155258 chr1:47152543-47154024;chr1:47154217-47155258 chr1:47154025-47154216 25 60.14 37.12 68.09 37.8 NA 10 38.16 25 61.54 29.45 11.9 50 41.67 57.89 68.69 54.55 55.91 22.22 51.22 28.79 60.87 34.75 43.88 59.68 39.06 48.15 34.57 30.43 38.21 26.02 46.15 30 28.57 50.44 18.87 29.27 40.74 26.37 14.52 28.95 45.38 35.53 33.77 58.82 46.15 22.73 54.72 42.86 46.9 25.78 23.81 38.1 41.3 62.67 58.33 40.51 45.95 38.2 47.96 44.44 27.94 36.36 29.73 52.63 42.11 52.05 30.51 36.54 19.72 45.95 30.38 60.82 40.28 28.15 36.49 32.88 44.05 45.07 21.25 57.5 67.24 80 33.33 58.9 67.39 53.27 20.24 51.02 52.17 44.9 25.42 44.3 50.91 43.82 33.33 53.91 28.38 48.51 21.57 43.9 24.03 43.24 55.93 30.97 50 54.13 30.63 36.57 60.82 40.78 41.33 75.78 34.55 43.1 43.01 36.26 36.43 34.55 63.19 53.41 35 66.46 53.76 35.79 39.62 26.87 41.18 39.78 62.22 31.3 39.29 53.85 49.41 54.41 46.15 51.49 28.07 18.46 32.26 38.6 51.39 100 47.69 26.32 33.33 39.39 37.74 26.47 57.75 NA 42.67 30.26 70.37 30.91 48.72 35.44 15.79 68.55 18.95 26.74 57.69 32.47 36.62 67.65 42.5 32.1 32.39 48.98 30.3 32.76 30.86 40.78 19.34 -21.45 0.000121 0.005678 N cassette KIAA0922 chr4 + chr4:154507532-154510041 chr4:154507532-154508893;chr4:154508964-154510041 chr4:154508894-154508963 NA 100 100 77.5 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 72.41 100 100 100 83.33 100 100 100 100 100 100 100 100 100 100 100 73.68 100 100 100 76.92 66.67 100 100 100 100 83.87 85.11 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 89.13 100 100 64.86 100 100 100 74.63 88.37 100 100 100 100 100 81.48 100 100 100 100 100 84.44 100 100 100 81.03 100 100 100 100 100 100 100 100 100 82.76 100 100 100 100 100 100 100 100 100 100 100 100 100 86.84 100 100 100 100 100 NA 100 100 100 100 100 NA 100 NA 100 100 100 70.59 100 100 100 100 80 100 100 100 100 75 100 100 100 100 100 71.43 100 100 76.84 -23.16 0 0.000013 N alternative_acceptor KIAA1033 chr12 + chr12:105558086-105558450 chr12:105558086-105558418 chr12:105558419-105558450 chr12:105558450-105558451 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.74 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 87.5 100 100 81.48 100 100 85.71 100 100 100 100 100 100 84.44 91.04 100 100 100 100 89.58 89.09 88.89 100 100 100 100 91.59 100 100 100 89.8 100 100 100 100 88.89 100 100 100 100 89.04 100 100 84.91 100 100 100 100 91.53 100 100 100 100 100 100 100 100 89.47 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90 100 100 100 100 100 100 88.24 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 94.19 100 100 100 100 100 100 100 100 100 100 100 100 100 87.93 100 100 100 92.42 100 100 100 100 100 100 100 100 100 88.41 -11.59 0.000006 0.000639 N cassette KIAA1632 chr18 - chr18:43496548-43503233;chr18:43497785-43503233 chr18:43497785-43502306,chr18:43496548-43502306;chr18:43502567-43503233 chr18:43502307-43502566 NA 100 100 100 100 NA NA 100 100 100 100 100 100 82.86 100 100 100 100 100 NA 100 NA 100 81.82 100 NA 100 100 100 100 100 100 100 100 100 100 100 85 100 83.87 100 100 100 100 100 100 NA 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 78.57 100 100 100 100 100 100 100 76.67 100 100 100 100 100 70.59 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.1 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 81.08 100 100 100 100 100 100 NA 100 100 100 NA 100 100 100 100 100 100 100 100 NA 100 NA 100 100 100 69.57 100 100 100 91.07 85.71 83.33 100 100 100 NA NA 100 100 100 81.25 100 100 100 85.71 -14.29 0.000093 0.004592 N alternative_acceptor KLRAQ1 chr2 + chr2:48688372-48692075 chr2:48688372-48689334 chr2:48689335-48692075 chr2:48692075-48692076 34.92 20.43 17.86 17.31 26.74 15 37.5 18.28 24.36 26.15 24.51 100 22.22 23.97 17.39 28.57 26.13 20.25 23.19 12.82 14 25.37 17.27 20.69 26.47 17.05 34.88 11.9 11.96 18.1 14.1 24 40 21.15 20 12.31 15.31 23.68 13.1 12.31 21.15 32.84 18.28 17.2 34.33 23.19 11.76 14.67 19.67 23.71 13.08 8.79 31.37 19.79 14.47 22.95 30 26.67 15.46 27.14 22.39 37.93 23.08 23.61 13.98 26.15 24.71 18.48 23.08 11 24.27 19.12 21.05 21.05 17.09 19.18 28 16.49 15.79 20 25.42 30.51 29.58 13.92 23.08 30.61 15.94 11.36 25.93 11.59 51.52 16.9 25.97 28.07 15.29 30.38 20.97 12.31 27.27 26.67 15.24 16.24 15.22 31.71 22.22 25.37 23.19 13.1 14.67 50 17.11 22.64 20 22.22 34.88 14.86 20.65 14.47 17.54 24.64 18.18 20.99 19.74 23.53 18.52 13.04 25.93 31.25 11.67 31.71 23.86 27.63 27.27 31.82 42.86 18.6 29.41 29.69 25.53 38.89 17.24 31.91 24.56 11.84 30.3 18.42 38.89 32.69 46.67 18.07 19.12 19.15 24.64 34.18 24.14 28.57 32.26 29.41 25.42 13.68 22.34 37.14 20.93 25 14.29 16.67 15.74 23.21 14.29 21.05 22.67 25.58 22.64 12.31 -10.33 0.00032 0.021059 K cassette LARP4 chr12 + chr12:50835427-50848096 chr12:50835427-50847242;chr12:50847456-50848096 chr12:50847243-50847455 NA 100 100 100 100 NA 100 100 100 85.92 100 100 100 100 100 100 84.44 100 100 100 100 100 100 87.8 100 100 100 80 100 82.86 83.67 100 100 100 100 84.38 100 100 100 79.07 100 84 100 100 100 100 100 81.48 87.5 100 83.52 83.33 100 100 89.36 100 100 84.85 91.67 100 84.91 100 88.89 84.38 86.67 100 100 100 89.8 81.97 88.89 86.21 89.33 89.8 100 100 84.38 100 100 89.09 100 100 100 100 88 79.17 100 74.19 100 81.69 100 100 100 100 88 100 91.94 100 100 100 86.76 88.14 100 100 89.29 100 100 100 79.49 100 81.4 100 83.64 100 91.25 88.33 100 100 100 85.92 87.5 100 87.76 84.09 100 100 100 100 100 100 84.88 100 100 100 100 100 88.71 100 100 100 100 100 100 100 100 87.76 100 100 100 100 100 100 100 100 100 100 100 100 82.11 83.33 100 100 100 80 80 100 92.42 87.8 100 79.17 86.49 80 100 83.33 -16.67 0.001272 0.028084 N cassette LEPROT chr1 + chr1:65891062-65897485 chr1:65891062-65895544;chr1:65895732-65897485 chr1:65895545-65895731 100 100 90.09 94.68 100 100 84 100 100 100 100 100 100 92.92 100 100 100 91.86 100 100 100 100 100 94.55 100 100 100 96.03 94.29 100 93.7 100 100 93.71 100 90.2 100 100 100 83.33 100 100 100 100 100 89.74 100 91.54 91.87 100 95.1 90.91 100 100 100 100 100 100 100 100 95.76 92.21 100 91.57 91.5 93.62 86.62 100 92.59 82.73 96.43 86.67 100 100 94.63 100 94.19 89.02 96.02 95.58 95.45 92.86 100 94.16 94.52 100 100 100 93.1 100 100 100 100 100 92.7 100 100 91.8 93.84 90.91 91.72 96.98 100 100 85.16 91.57 95.61 96.62 100 100 100 100 100 100 90.4 100 94.29 100 100 100 95.6 100 100 91.67 93.6 94.26 100 100 100 100 100 100 100 100 100 100 100 100 96.06 100 100 100 100 92.86 100 100 100 100 100 100 100 100 95.24 100 86.27 92.93 94.4 93.2 97.04 88.24 93.98 100 93.27 95.65 100 100 93.46 92.25 100 95.1 93.62 96 100 89.22 -10.78 0.000822 0.020307 K alternative_last_exon LEPROTL1 chr8 + chr8:29962003-29962249,chr8:29962003-29989491;chr8:29962003-29994787 chr8:29962003-29963261 chr8:29994788-29995222 chr8:29963262-29965586 96.1 92.05 93.15 70.65 96.67 71.74 67.35 88.57 87.06 95.73 94.37 87.06 89.71 83.65 93.7 73.38 82.31 94.31 87.6 84.38 82.95 85.9 93.66 85.71 60.81 59.89 93.68 88.46 78.63 73.68 96.22 92.94 89.83 76.64 91.59 48.08 86.45 84.21 90.24 61.45 97.01 96.71 67.8 85.29 91.25 83.61 77.55 90.98 79.83 77.56 83.23 59.77 84.62 97.34 75.32 77.92 96.97 85.8 90 89.25 80.7 75.93 78.67 97.78 94 83.33 81.31 89.77 84.56 85.35 93.02 94.19 78.87 95.33 88.96 94.16 81.18 96.43 85.47 73.79 90.48 94.25 77.38 73.47 92.97 57.77 96.1 93.1 94.67 65.15 91.74 68.46 93.75 94.32 83.8 84.54 90.91 85.21 94.57 85.89 80.32 83.67 77.65 90 87.37 89.74 91.84 71.2 67.14 80.22 85.71 75.18 79.56 88.73 80 94.07 84 80.69 92.45 92.02 76.04 85.71 69.61 93.75 90.91 75 90.79 94.29 72 90.18 91.55 93.91 91.6 96.51 91.23 92.73 92.19 77.65 91.86 74.55 71.3 92.45 93.58 82.76 96.2 76.07 91.53 91.46 95.04 91.46 94.38 84.11 83 73.68 93.85 95.52 89.8 87.04 70.09 68.18 95.18 91.67 84.89 94.9 57.5 85.37 92.78 94.51 95.24 88.66 84.88 90.68 88.66 64.81 -23.84 0.000611 0.048555 N cassette LETMD1 chr12 + chr12:51442969-51449617;chr12:51442969-51449926 chr12:51442969-51447594;chr12:51447644-51449617,chr12:51447644-51449926 chr12:51447595-51447643 100 100 100 75 100 62.5 81.58 100 100 100 100 NA 100 100 100 NA 100 85.29 100 NA 100 NA NA 100 100 100 100 100 100 100 100 100 NA 59.09 100 NA 100 80 100 76.92 NA 100 100 100 100 NA 100 100 100 82.35 75 67.35 100 100 78.26 100 100 NA 100 100 66.67 NA 100 81.82 100 100 NA 100 80 68.75 88.24 100 100 100 71.43 100 68.42 83.87 100 100 100 100 100 80 100 100 100 68.57 100 68.29 NA 72.97 100 100 100 100 72.73 75 74.19 100 100 86 76.32 100 80 81.25 100 78.57 100 100 50 100 69.05 100 76.67 100 61.54 100 100 100 82.14 100 83.33 75 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 78.95 100 70.83 100 100 NA 100 100 100 100 100 100 100 100 NA 65.22 76.47 100 100 100 100 65.38 81.48 100 82.35 85 NA NA 100 100 72.97 -27.03 0.000182 0.007629 K cassette LIAS chr4 + chr4:39462583-39465144 chr4:39462583-39463815;chr4:39463910-39465144 chr4:39463816-39463909 NA 100 100 100 100 100 NA 100 73.68 100 100 NA NA 100 100 NA 100 100 73.33 NA 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 86.84 100 66.67 NA 100 NA 100 NA 71.43 100 100 100 77.78 100 63.64 100 100 100 NA NA 65.38 100 NA 83.33 NA 100 NA 68.42 NA 100 100 100 56 100 70.59 72.41 100 100 66.67 100 41.67 100 100 NA 100 NA NA NA 100 100 100 100 63.16 NA NA 61.9 100 100 NA 100 73.08 100 NA 79.41 100 100 100 100 72.22 73.08 72 100 100 57.14 NA 100 100 100 100 76.19 100 100 100 75 100 100 100 100 NA 100 NA NA NA 80 100 100 100 NA 100 100 100 100 NA 100 100 100 100 68.75 78.26 100 76.19 NA NA 100 NA 79.17 69.57 100 NA 100 NA 100 66.67 100 100 64.71 100 100 100 100 59.09 100 100 100 100 100 66.67 -33.33 0.000531 0.014924 K cassette LIG1 chr19 - chr19:48664765-48668806 chr19:48664765-48665518;chr19:48665609-48668806 chr19:48665519-48665608 100 100 100 87.8 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 93.06 100 100 100 90.41 100 100 100 80.65 100 100 100 86.21 100 91.67 100 85.48 100 100 100 100 100 86.49 100 100 100 100 87.5 88.89 100 92.96 100 91.23 100 89.39 100 94.12 100 100 100 86.27 100 100 100 100 100 100 100 100 100 91.38 100 100 100 100 100 100 100 100 100 100 100 100 100 100 87.64 100 100 100 100 100 100 NA 85.71 95.73 92.94 93.24 100 100 100 100 90.24 100 92.55 100 100 100 100 84 91.03 100 100 100 100 100 100 100 100 100 89.86 89.39 100 100 100 100 100 82.86 100 100 100 100 100 100 100 100 100 100 100 100 100 90.23 100 100 100 100 100 100 100 100 100 91.07 100 100 100 100 93.42 82.14 100 100 100 100 100 100 100 90.74 100 100 100 84.38 100 87.55 -12.45 0.000986 0.022921 K alternative_last_exon LMF1 chr16 - chr16:932154-943006;chr16:929738-943006 chr16:931506-943006 chr16:929570-929737 chr16:931419-931505 NA 20 38.89 15.38 15.38 29.17 30 NA 22.22 64.71 28.57 NA 13.64 50 NA 22.22 30.61 24.24 18.97 NA NA NA NA 22.58 28.12 NA NA 11.11 37.5 25 7.14 5.88 25 20 NA 9.09 11.11 14.55 28 2.7 30.3 12.5 10 8.33 10 30 16.22 20 21.88 32.35 10 11.11 17.54 30.43 32.26 56.76 11.11 19.23 26.19 16.28 18 20.59 25 8.33 25.81 7.14 41.18 20 25 3.12 7.5 13.33 7.14 35.42 23.08 23.08 12 4 37.14 12.12 21.05 21.43 46.88 33.33 35.71 32.26 7.41 19.05 29.41 6.45 18.18 0 25.93 NA 4.17 NA NA 15.38 24.59 18.18 32.61 35.48 34.21 18.42 40 13.33 30.95 36.59 5.88 23.53 22.22 3.85 48.57 16.67 21.43 9.68 16.67 NA NA 34.88 4.17 22.22 12 26.47 NA 27.03 27.78 18.18 28.57 NA NA NA 18.18 6.67 NA 20 21.43 4.55 40 NA 52.38 NA 8.33 24.49 11.11 32.14 22.58 29.03 NA NA NA NA 50 28 20.93 26.67 41.86 19.57 15.56 7.69 5.41 20.45 32.5 21.95 27.78 10.53 23.4 20.45 22.73 35 20.93 15.91 21.91 5.41 -16.51 0.000393 0.034752 N alternative_acceptor LOC339047 chr16 + chr16:16485954-16486432;chr16:16485954-16487312 chr16:16485954-16486449 chr16:16486433-16486449;chr16:16486450-16487312 chr16:16486449-16486450;chr16:16487312-16487313 42.03 53.9 43.91 27.27 56.85 21.6 29.2 46.84 51.16 51.47 56.04 44.96 44.98 49.2 48.23 47.43 27.99 37.25 45.77 33 51.06 43.69 56.8 36.67 39.34 35.21 60.45 30.6 51.38 50.92 33.25 44.63 46.8 41.39 58.53 22.26 53.55 41.21 38.47 37.15 45.95 50.63 49.5 49.21 58.01 44.97 32.3 35.38 48.61 47.64 42.13 32.62 47.89 42.11 36.91 41.43 37.32 46.86 53.26 43.43 52.63 49.72 50 30.48 42.86 40.08 49.18 45.71 53.66 31.53 36.67 46.06 55.13 42.36 45.83 49.87 44.94 43.75 47.18 34.59 39.8 49.61 37.17 45.65 40.33 47.33 51.51 45.12 33.84 25.38 51.42 35.32 44.41 59.9 37.84 56.25 55.93 36.15 45.97 27.91 44.12 47.99 32.87 43.36 34.89 31.96 45.2 46.2 38.34 46.67 43.54 31.88 46.82 53.71 46.14 48.14 59.74 52.29 44.26 50.9 36.22 54.27 40.73 38.8 56.11 27.35 45.41 58.01 35.13 50.63 47.57 51.5 47.94 59.43 49.75 42.67 50.15 56.36 50.33 47.83 37.31 51.44 44.42 36.88 58.61 40.89 48.49 52.42 22.94 51.13 46.11 53.21 46.15 34.12 33.33 49.52 44.19 42.46 36.58 27.61 41.16 40.07 44.73 34.02 26.05 39.07 42.45 38.82 40.27 52.4 34.76 33.6 45.12 32.08 -13.04 0.000672 0.031216 K cassette LOC339047 chr16 - chr16:18452446-18453804 chr16:18452446-18453238;chr16:18453309-18453804 chr16:18453239-18453308 21.5 28.19 19.72 13.42 31.79 11.48 19.91 28.44 31.33 30.04 30.36 27.16 16.83 29.34 30.84 32.99 15.49 16.04 29.81 21.08 26.06 16.43 38.02 21.57 28.18 16.88 33.82 16.37 31.34 27.81 13.83 26.21 28.34 23.82 32.74 8.1 28.57 19.58 20.42 10.68 20.63 21.17 27.04 29.53 35.16 19.75 24.15 20.56 26.96 23.93 22.47 9.18 22.04 25.12 17.43 22.52 16.06 22.43 26.42 22.09 27.44 30 24.24 10.73 23.46 21.22 33 21.65 28.63 9.89 17.1 22.88 35.93 18.11 24.04 21.46 25 22.05 23.83 24.56 20 20.26 14.65 24.23 23.2 18.59 25.29 20.92 22.77 12.15 31.87 10.76 21.03 29.47 13.15 30.88 32.89 19.85 19.03 12.56 36.48 27.24 22.38 20.62 9.77 10.61 24.01 33.75 25.63 19.7 21.84 16.1 19.47 38.33 21.38 20.39 38.33 38.22 20.75 27.46 15.07 21.89 20.85 17.63 29.81 14.73 22.67 25.93 20.17 23.66 31.34 29.9 31.75 25.62 27.56 21.19 28.11 33.75 29.15 22.48 20.55 22.65 22.22 17.73 36.07 27.68 25.39 27.13 13.7 22.22 28.57 26.15 30.34 24.07 15.46 23.04 22.57 25.86 17.73 8.19 23.58 22.97 26.23 20 12.87 30.75 23.51 16.67 19.24 24.48 18.21 18.91 22.97 9.54 -13.43 0.000039 0.002293 K cassette LOC339047 chr16 + chr16:16442590-16443948 chr16:16442590-16443085;chr16:16443156-16443948 chr16:16443086-16443155 21.28 27.81 19.24 13.42 31.79 11.11 19.76 28.3 31.14 29.29 29.82 29.76 16.67 28.99 30.52 32.02 15.49 15.72 29.72 20.59 25.35 16.31 37.7 21.55 27.82 16.25 33.58 16.18 31.23 27.49 13.54 25.73 27.94 23.46 31.58 8.06 28.34 19.22 20.32 10.68 20.42 21.17 26.77 29.24 35.48 19.28 23.99 20.33 26.88 23.7 22.28 9.05 21.92 24.43 17.12 22.11 15.94 22.02 26.29 22.18 27.37 29.38 24.06 10.73 23.28 21.26 32.75 21.46 28.76 9.66 16.86 22.46 36.41 17.98 24.04 21.36 25 21.72 23.46 24.71 19.25 20.09 14.47 24.23 23.05 18.59 24.63 20.92 22.87 12.08 32.3 10.83 20.85 28.87 13.2 30.88 32.68 19.4 18.58 12.5 36.23 27.24 22.2 20.43 9.51 10.53 23.9 33.5 25.31 19.55 21.98 15.99 19.28 37.7 21.45 20.05 38.49 37.85 20.08 27.02 14.67 21.64 20.79 17.91 29.81 14.73 22.52 26.25 20.08 23.66 30.77 29.59 32 25.62 27.56 21.33 27.73 33.13 29.15 22.22 20.62 22.51 22.37 17.73 35.48 28 25.26 26.4 13.7 21.43 28.57 28.33 30.25 23.5 14.98 22.4 22.43 25.31 17.65 7.8 23.05 22.86 25.57 20 12.61 30.12 23.36 16.44 19.5 24.48 18.1 18.7 22.86 9.36 -13.5 0.000039 0.002293 K cassette LOC339047 chr16 + chr16:16427742-16434162 chr16:16427742-16429908;chr16:16429995-16434162 chr16:16429909-16429994 33.85 17.2 25.16 12.3 25.91 12.01 12.82 22.87 30.13 35.66 28.26 4.11 25.12 19.66 36.94 47.8 20.64 21.49 35.93 28.12 24.42 12.06 27.05 36.97 36.9 10.59 30.13 26.1 32.56 40.67 19.18 21.74 25.69 32.74 17.1 50.64 30.88 32.24 31.09 41.48 22.98 20.24 24.35 16.71 27.09 43.64 35.65 22.03 34.52 26.53 23.19 34.93 31.34 13.21 12.12 15.03 15.11 17.66 35.44 26.58 22.96 22.65 26.11 21.5 38.65 30.66 41.4 31.58 26.64 42.54 20.77 48.47 36.11 28.86 29.53 39.61 43.18 22.75 24.89 26.41 27.32 18.43 13.53 21.01 29.6 21.32 19.71 27.05 21.31 24.57 37.82 35.23 20.18 23.64 26.92 22.11 15.25 22.49 34.48 19.96 36.61 25.6 33.8 22.57 15.51 23.55 32.51 29.2 35.88 11.48 35.53 13.49 10.32 30.43 24.78 18.02 27.54 21.38 28.5 21.98 26.56 18.03 10.71 22.75 45.69 20.38 29.14 30.21 22.71 9.16 22.5 13.13 31.48 29.28 16.54 24.11 24.68 31.55 20.81 17.12 16.8 18.37 11.63 22.82 29.93 24.58 31.47 25.25 28.09 27.86 14.04 24.51 28.57 20.23 26.64 32.06 34.41 33.45 26.89 54.05 26.06 30.27 29.44 32.2 11.27 19.13 30.65 22.32 27.14 26.97 20.28 19.06 25.25 42.01 16.76 0.000214 0.00863 N cassette LOC401320 chr7 - chr7:30591012-30601081;chr7:30590398-30603346;chr7:30590398-30601081;chr7:30591096-30601081 chr7:30590398-30591715,chr7:30591096-30591715,chr7:30591012-30591715;chr7:30591796-30603346,chr7:30591796-30601081 chr7:30591716-30591795 53.33 50.55 35.48 16.67 36.67 54.55 55.33 50.77 37.78 100 57.14 NA 28.12 64.77 35 64 47.37 28.89 47.46 NA 50.82 100 52 52.73 79.71 NA NA 48.57 58.7 65.79 20 50 NA 35.64 41.18 100 41.38 37.5 39.13 100 55.13 11.11 57.75 58.73 53.62 42.31 53.26 41.18 58.33 47.83 39.29 82.76 68.18 40 36.36 52.11 24.32 30.3 48.65 47.83 45.61 20.55 41.43 16.13 43.24 52.17 68.33 39.22 42.86 65 52.83 NA 43.48 41.18 46.83 44 41.07 18.42 59.77 51.9 39.62 40.48 58.7 58.44 37.1 54.76 34.78 18.92 42.05 63.24 51.61 NA 48.65 22.73 35.24 65.22 45.16 15.87 45.83 28.57 61.66 71.53 54.1 44.44 20 29.41 47.71 68 61.47 100 48.43 40 33.33 NA 28 33.04 22.5 34.48 27.27 61.54 31.51 26.39 39.24 25.96 42.59 13.33 47.06 28.12 65.91 41.67 60.98 0 48.65 28.57 100 100 53.66 28.26 56 63.83 57.89 53.45 16.67 34.43 41.18 75.53 37.35 36.84 20 100 NA 39.39 50 63.16 60.71 41.18 50.93 67.31 25 87.3 49.23 45.33 31.43 42.37 NA 68.18 32.61 34.48 37.5 32.84 36.59 28.89 43.48 87.3 43.82 0.000567 0.015429 K alternative_acceptor LOC653390 chr16 + chr16:29107583-29108513 chr16:29107583-29108452 chr16:29108453-29108513 chr16:29108513-29108514 100 84.54 76.87 88.71 87.6 100 85.59 79.17 84.54 85.9 83.65 100 84.13 88.44 76.71 88.14 83 84.38 93.68 100 89.71 100 79.86 81.25 87.69 100 81.33 76.92 87.18 85.9 89.66 87.83 78.82 100 85.87 62.5 79.09 86.78 85.26 73.68 71.43 100 100 87.78 100 87.95 82 83.13 89.52 92.8 86.57 59.09 89.02 90.24 100 92.63 100 92.59 84.8 84.44 83.96 89.13 86.67 100 84.92 76.62 84.54 81.1 86.87 72.41 83 84.11 85.33 83.67 85 90.14 81.11 91.25 91.75 87.06 88.24 87.01 100 86.84 91 85.11 100 88.33 82.8 81.93 100 50 100 85.33 90.74 82.28 84.62 88.76 83.92 87.84 85.44 85.83 100 88.33 84.82 83.51 84.75 87.9 82.18 100 87.21 81.61 84.68 100 93.81 90.1 82.73 85.12 81.93 94.44 83.46 81.69 84.78 88.16 91.14 100 83.95 77.48 86.29 100 83.5 100 88.78 88 76.54 80.72 83.33 80.21 90.22 78.08 100 89.13 100 88.7 90.77 89.41 88.46 86.46 100 100 100 100 84.15 88.37 86.3 86.67 78.3 80.61 85.05 64.79 85.23 80 88.98 89.89 100 74.24 88.89 84.72 86.55 85.53 77.78 90.16 86.78 63.65 -23.13 0.000034 0.003309 N cassette LOC728190 chr10 - chr10:89086430-89096542 chr10:89086430-89090648;chr10:89090854-89096542 chr10:89090649-89090853 33.33 32.69 43.84 48.72 61.54 43.75 45.45 62.07 46.15 47.56 52.38 100 46.51 49.02 39.68 32.53 44.93 38.71 44 33.33 44.12 33.33 38.1 32.61 47.06 38.46 40 43.9 48.65 41.03 43.33 52.24 44.44 27.69 33.33 13.04 34.48 36.05 37.97 20.41 55.56 48.15 44.12 45 63.64 25 37.14 50 44 33.33 39.06 29.73 46.81 46.15 30.3 28.12 56.41 42.42 35.14 52.08 37.5 33.33 59.38 39.13 51.56 64.71 53.33 28.57 40.68 42.62 45.95 37.14 48.94 43.66 36.67 31.03 53.7 41.86 48.48 47.17 48.28 35.71 54.05 48.28 44.51 30.16 34.88 53.33 44.44 39.68 58.49 26.42 45.45 38.1 41.94 72 48.7 40.35 35 42.31 30.59 40.38 33.33 33.33 62.32 47.47 39.74 43.72 22.22 50 40.3 48.78 29.58 51.43 27.43 29.41 36.36 52.83 38 53.66 48.44 46.08 29.69 32.04 56.25 39.77 41.03 38.78 48.98 36.73 66.67 31.67 33.33 40.3 47.62 51.52 41.82 40.43 46.75 52.83 41.3 40.74 25 32.1 36.36 31.58 45 25.53 39.2 53.33 30 43.48 44.83 41.67 48.28 46 57.69 38.46 48.44 30.43 45.45 36.62 40.35 50 25.53 20.59 47.17 40.54 42.11 41.3 41.18 64.71 41.94 28.08 -13.86 0.001772 0.036195 K cassette LONP2 chr16 + chr16:48286277-48292528 chr16:48286277-48290520;chr16:48290653-48292528 chr16:48290521-48290652 100 84.34 100 83.93 100 100 NA 100 100 100 100 100 100 100 100 89.29 93.75 100 100 100 89.8 100 100 100 100 100 100 92.21 91.67 100 95.37 100 100 100 100 82.98 100 100 89.77 81.71 100 100 100 100 100 100 100 93.68 100 91.67 100 82.98 100 88.6 93.51 100 90 100 100 92.16 93.18 100 89.47 100 94.32 88 100 89.19 90.7 93.98 91.89 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 89.87 100 100 77.55 100 100 100 100 100 88.3 100 100 100 100 100 100 94.79 100 100 100 100 100 100 100 93.75 100 100 100 100 100 100 93.94 89.11 100 92.13 93.97 100 100 89.36 100 88.61 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 87.01 100 100 100 100 100 100 87.69 100 100 87.93 94.83 85.56 89.87 100 95 100 90 100 100 93.33 100 100 100 100 100 82.98 -17.02 0.000001 0.000069 N cassette LRRC37A chr17 + chr17:44383676-44407815;chr17:44400394-44407815 chr17:44400394-44405757,chr17:44383676-44405757;chr17:44405877-44407815 chr17:44405758-44405876 100 91.84 89.26 81.52 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 83.33 100 100 100 86.11 100 100 93.33 100 100 95.51 90.67 100 100 88.89 100 100 84.15 100 100 83.12 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 94.85 100 89.01 100 100 88.07 100 100 100 100 100 100 100 100 94.34 100 100 100 100 100 100 100 95.15 100 100 100 100 93.24 100 100 100 100 88 100 100 100 100 100 91.27 94.68 100 100 100 87.3 100 83.61 100 100 100 100 80.56 100 100 88.49 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 84.04 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 94.83 100 82.56 100 100 94.19 93.1 100 100 100 100 100 89.17 90 100 100 87.56 -12.44 0.000332 0.011758 N cassette LRRC37A2 chr17 + chr17:44618248-44625677 chr17:44618248-44623620;chr17:44623740-44625677 chr17:44623621-44623739 100 90 91.59 80 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 91.3 92.11 100 100 89.71 100 100 100 87.1 100 100 100 100 100 96.39 100 100 100 88.14 100 100 83.12 100 100 89.55 100 100 100 91.14 100 100 100 100 NA 100 100 100 94.19 100 100 94.74 100 90.27 100 100 89.52 100 100 100 100 100 100 100 100 94.95 100 100 100 100 100 100 91.55 100 100 100 100 100 100 100 100 91.6 100 91.8 100 100 100 100 93.8 92.25 100 95.19 100 100 87.5 100 87.5 100 100 100 85.92 80 100 100 89.86 100 100 100 93.64 100 100 100 93.6 100 100 100 100 100 100 100 100 86.59 100 100 85.71 100 100 100 100 100 100 100 100 100 100 100 100 93.88 100 100 100 94.59 100 80.25 100 100 100 100 88.06 100 100 100 100 90.91 89.62 100 100 89.91 -10.09 0.002712 0.048759 K coord_cassette LRRC37A3 chr17 - chr17:62865285-62885798 chr17:62865285-62882203;chr17:62882285-62882932;chr17:62883005-62885798 chr17:62882204-62882284;chr17:62882933-62883004 100 100 84.75 82.5 100 54.55 100 100 100 100 80 100 84.85 81.4 100 100 75 81.69 80.56 NA 84.85 100 76.27 100 100 100 100 100 69.44 82.35 66.67 84.48 100 100 84 71.43 80.85 77.78 84.21 53.85 86.49 80.21 62.07 78.38 100 100 NA 81.82 68.97 100 100 82.86 75 100 100 100 100 83.72 100 61.54 100 88.89 88.64 100 100 87.18 88.1 100 76.92 49.09 78.38 82.05 65.22 81.82 72.97 77.78 83.78 73.91 83.78 100 87.5 85.19 100 100 100 100 100 100 100 78.05 100 83.87 100 100 66.67 100 85.92 70.37 100 76.67 72.86 88.89 100 100 77.78 65.91 89.58 64.44 79.49 89.36 63.27 70 81.97 100 100 67.31 73.91 100 100 100 55.56 83.33 84.38 100 81.25 58.33 100 62.16 73.08 100 87.8 100 100 100 100 100 86.76 78 100 100 82.98 100 100 100 100 100 100 84.13 100 100 NA 100 85 100 100 100 83.78 76.19 100 67.74 81.08 78.72 100 100 80 81.48 100 63.33 100 64.52 100 85.29 89.12 69.59 -19.54 0.002035 0.04755 N coord_cassette LRRFIP2 chr3 - chr3:37138152-37170553 chr3:37138152-37162982;chr3:37163028-37163125;chr3:37163183-37170553 chr3:37162983-37163027;chr3:37163126-37163182 0 8.96 2.63 4.88 0 NA 6.25 0 0 0 2.88 NA 2.38 0 0 5.56 14.63 1.67 1.3 0 4.08 0 0 3.23 3.45 3.23 1.47 6.67 5.56 8.33 9.23 3.64 0 0 2.33 17.95 0 2.7 1.67 9.52 0 0 5.56 1.79 0 0 2 8.57 0 3.8 5.88 16.67 0 0 13.04 3.12 0 0 3.23 3.23 2.86 0 15.62 2.22 5.36 5.88 0 1.92 2.22 21.36 7.89 2.33 7.69 0 2.04 6.15 4 0 0 0 3.12 2.44 0 0 0 1.64 0 0 3.03 0 3.57 6.9 0 1.35 1.22 0 0 2.7 2.78 6.25 5.56 0 0 2.86 9.09 7.14 0 1.16 2.33 10.71 4.44 0 4.35 0 3.85 1.56 4 10.64 1.16 8.82 4.6 1.89 2 1.79 0 2.04 1.56 3.57 5.8 2.33 0 6.15 2.27 0 0 0 3.23 NA 0 0 5.71 0 0 0 0 11.86 0 4.44 0 0 8 2.38 2 0 3.23 0 0 2.17 3.28 21.05 1.69 0 3.53 0 10 5 0 3.03 1.96 0 0 3.03 1.94 17.31 15.37 0.000045 0.00233 K cassette MAP3K3 chr17 + chr17:61710163-61723393 chr17:61710163-61712068;chr17:61712162-61723393 chr17:61712069-61712161 NA 21.99 24.42 34.88 28.81 38.1 64.84 35.14 27.08 25 31.19 16.33 32.81 41.25 24.24 17.39 24.71 37.04 27.12 12.5 36.67 27.72 30.89 31.82 28.57 25.13 19.05 39.85 35.14 28.42 24.21 34.62 16.67 29.09 32.43 42.86 33.33 28.36 33.33 35.16 44.3 14.85 37.7 22.58 26.73 11.63 28.79 33.33 30.23 32.65 28.57 50 29.63 39.62 25.71 22.22 48.89 35.29 33.33 20.44 27.66 30.51 52.26 22.22 29.41 30.3 17.65 21.62 27.73 43.53 31.65 21.95 17.46 19.74 28.85 32.1 35.11 30.26 36.59 31.25 35.9 30.43 26.47 42.17 24.32 17.24 24.24 32.76 24.8 29.69 31 49.15 32.35 23.64 19.84 39.84 16.9 28.92 12.33 34 33.9 36.46 34.48 27.27 22.68 26.96 15.79 28.57 25.87 28.41 22.88 42.86 13.33 28.3 16.67 23.81 16.88 19.83 21.57 34.48 25.45 30.83 18.71 37.84 22.22 25.77 24.44 36.36 36.23 31.15 25.86 32.61 29.31 19.61 54.55 29.07 30.91 51.02 47.37 26.74 21.95 21.21 20 25.33 31.82 25.93 25 29.17 NA 26.72 NA 35.43 29.03 15.38 48.65 22.64 33.33 31.37 33.33 40.7 27.66 29.73 26.14 36.36 30.77 37.14 30.23 14.29 26.58 55.56 46.67 32.08 28.89 43.2 14.31 0.000444 0.013931 K cassette MAP3K7 chr6 - chr6:91246121-91256976 chr6:91246121-91254270;chr6:91254352-91256976 chr6:91254271-91254351 NA 16.33 19.05 6.06 13.04 NA 4 7.14 12.28 10.53 19.35 NA 6.9 21.74 5 15.22 7.55 4.88 30.43 30 13.04 6.25 15.62 8.16 0 37.04 29.63 8.11 27.27 25 22 21.88 NA 5 4.55 32.35 14.29 15.94 3.7 38.89 0 55.17 10.61 10.81 26.67 32.14 23.08 22.08 2.56 11.32 19.74 32.14 19.05 27.27 18.18 8.51 5.88 17.5 20 19.67 30 15.79 27.27 14.52 9.59 22.58 29.41 19.15 6.25 27.27 13.11 12.5 19.35 33.33 14.04 4.55 27.03 7.14 15.56 17.65 5.56 26.83 28 15.15 31.71 7.14 13.04 18.75 18.31 7.41 23.08 45.83 4.35 5.56 10 10 20.59 48.94 18.52 8.33 26.87 22.39 16.67 18.18 16.67 20 14.29 11.69 18.67 28.57 21.74 18.75 25.42 20 38.18 22.22 30.23 27.96 3.57 19.05 5.26 26.53 21.33 18.97 17.31 23.53 3.45 15.38 14.08 7.41 22.73 27.03 10.26 25 11.11 0 20.51 26.09 58.82 5.56 4 22.86 0 8.96 25 16.07 NA 16.22 NA 8.33 NA 21.05 37.5 20.51 10.26 17.39 17.02 16.22 19.15 64 19.15 5 8.77 31.03 17.07 8.89 16.98 18.6 21.54 23.4 18.18 11.76 17.35 35.62 18.27 0.000159 0.006927 N alternative_acceptor MARK3 chr14 + chr14:103941548-103946773 chr14:103941548-103946723 chr14:103946724-103946773 chr14:103946773-103946774 100 100 100 100 100 100 96.27 100 93.7 100 88.66 100 100 100 100 85.11 84.21 91.49 92.62 100 100 100 100 90 90.08 100 100 100 92.97 93.48 94.07 100 100 100 100 87.36 93.16 94.15 94.74 90.65 100 87.1 95.54 86.3 100 88.89 93.62 100 100 93.69 100 87.06 94.77 100 100 100 100 100 92.79 100 100 100 95.9 90.29 88.89 100 92.02 88.17 100 91.27 90.12 100 100 92.92 97.3 100 100 100 84.04 84.75 100 94.51 93.55 100 83.78 100 100 100 100 100 84.85 87.5 100 100 100 100 87.85 89.08 92.08 100 88.37 93.24 96.34 100 86.92 91.59 100 90.42 90.83 87.5 100 91.39 100 100 100 100 92.14 91.86 100 95.3 100 90.27 87.42 90.85 95.9 100 100 100 94.53 87.5 100 100 100 100 100 100 100 100 100 100 84.3 100 100 100 100 95.3 100 100 100 100 100 100 93.39 88.97 100 100 100 93.1 96.08 82.86 94.54 91.1 100 88.5 100 93.23 88.89 94.7 100 100 90.91 100 100 87.43 -12.57 0.000182 0.013624 N alternative_acceptor MARK3 chr14 + chr14:103933529-103934369;chr14:103933529-103934422 chr14:103933529-103934417 chr14:103934370-103934417;chr14:103934418-103934422 chr14:103934417-103934418;chr14:103934422-103934423 1.27 18.06 25.61 13.46 10.53 3.45 14.86 1.19 22.55 22 23.21 NA 20.37 15.71 19.12 15.91 39 1.82 29.82 20 19.4 1.96 1.75 25 20 1.49 1.61 29.29 22.22 20.55 15.48 20 3.45 1.32 1.79 28.81 21.98 19.27 16.67 24 3.92 17.44 19.7 23.6 20.65 30 18.84 20.16 24.19 27.5 15.32 38.46 19.23 13.21 1.69 18.67 20.75 31.71 21.33 26.67 31.51 17.81 25.89 13.25 18.57 17.39 24.74 15.87 22.99 39.56 16.67 1.43 27.69 19.44 18.71 12.35 24.69 9.41 13.33 30.56 15.71 24.69 1.28 27.17 1.43 2.56 2.78 20 15.85 25.81 1.96 29.55 31.03 25.81 1.05 15.25 1.35 25.97 18.52 24.62 19.83 23.14 22.45 16.22 20.55 19.74 21.28 31.68 17.44 2 27.66 11.96 18.68 3.12 22 23.61 13.25 19.82 45.24 11.82 16.67 23.81 15.56 11.88 27.59 15.66 25.53 4.88 22.89 22.22 23.29 2.44 20.69 14.81 18.64 1.19 9.2 1.52 44.21 3.7 17.33 21.69 1.61 16.19 16.67 20.72 1.54 21.31 4 17.78 3.45 25.93 31.46 21.05 33.77 20.79 24.56 19.78 14.71 36.23 19.47 1.23 15.49 17.95 1.64 11.76 23.94 23.3 20.24 22.39 3.64 26.03 18.7 32.89 14.2 0.000294 0.019947 N cassette MBIP chr14 - chr14:36780932-36783717 chr14:36780932-36781164;chr14:36781231-36783717 chr14:36781165-36781230 100 100 100 100 100 100 85.07 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 66.67 100 100 100 83.33 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 83.87 100 100 100 100 84 100 100 100 100 100 100 100 100 100 100 NA 100 89.13 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 79.41 100 100 100 100 100 NA 100 100 100 NA 100 100 100 83.33 -16.67 0 0 K cassette MBTD1 chr17 - chr17:49284367-49294694 chr17:49284367-49286674;chr17:49286792-49294694 chr17:49286675-49286791 5 13.51 10.29 24.39 15.62 NA NA 13.64 16.67 9.09 3.12 NA 25 10.34 15.25 15.15 18.18 11.32 10 13.33 14.81 7.14 29.03 10.64 6.67 NA 23.81 8.33 17.86 9.09 13.04 10.26 17.65 NA 8.89 21.74 12.82 19.05 10 28.57 26.67 18.07 23.08 10.26 16.67 17.07 NA 14.29 16.67 22.45 9.52 27.27 23.53 16.67 19.61 18.75 21.88 6.98 18.18 11.76 23.26 23.21 33.33 16.28 18.84 10.34 20.93 22.73 24.39 31.58 12.5 24 19.67 24.62 3.7 17.07 16.07 13.51 14.29 17.24 28.57 25 13.33 16.67 8.33 8.11 5.88 13.64 21.05 20.83 NA 30.43 31.25 12.9 12.2 18.18 9.09 25.93 24.56 33.33 14.29 23.44 13.33 22.58 28.81 26.67 19.23 20.45 18.52 10.71 21.74 12 26.87 33.33 22.22 21.82 23.26 21.74 26.09 21.05 25.49 20.37 14.29 8.2 28.26 4.35 25.81 14.81 15.79 26.67 21.05 14 12 6.52 NA NA 12 15.38 14.29 NA 37.5 18.75 NA 9.09 10.71 25 29.63 20.83 NA NA NA NA 16.67 22.73 11.76 34.62 16.33 26.67 16.33 22.64 18.92 14.29 24.07 23.26 21.43 9.09 16.98 29.73 19.67 14.55 18.75 21.74 16.83 27.92 11.09 0.001879 0.037884 K alternative_acceptor MCTP2 chr15 + chr15:94899531-94901775 chr15:94899531-94901710 chr15:94901711-94901775 chr15:94901775-94901776 NA 75 82.76 100 78.26 NA NA 100 84.85 100 75 100 100 76.27 100 65.62 50.82 56.34 63.16 NA 64.29 100 100 53.33 NA 100 100 71.43 100 73.17 72 100 NA 67.65 100 NA 57.69 81.67 73.58 35 55 83.67 100 70.37 NA 88.18 100 73.77 69.66 78.26 51.52 NA 77.27 67 74.51 NA 46.77 78.26 74.6 79.17 63.08 52.94 68.57 75.86 89.36 NA NA 67.31 75 40.48 70.59 71.15 79.14 74.14 100 75.41 66.67 80.49 68.33 80 57.58 71.05 70 100 73.56 100 48.57 66.67 60.66 NA 59.38 27.27 100 69.23 81.48 62.96 66.67 89.47 100 100 69.7 60.98 NA 71.43 62.77 67.21 76.12 80.49 NA 66.67 66.67 72.92 80.77 100 80 72.73 84.75 68.82 74.07 67.65 56 73.68 50 52.17 81.58 66.67 74.14 56 76.67 66.3 100 63.27 100 67.65 NA 100 100 52.63 73.08 NA 51.85 62.71 100 85.19 74.42 75.86 100 60 NA NA NA 100 70 66.67 66.1 78.85 48.39 64 63.45 24.32 66.67 100 77.33 69.23 NA NA 76.32 73.08 75 64.29 71.74 72.41 73.58 31.13 -42.45 0.000648 0.03038 N cassette ME2 chr18 + chr18:48458731-48466657 chr18:48458731-48465939;chr18:48466011-48466657 chr18:48465940-48466010 100 80.65 90.07 82.35 89.15 72.73 61.04 88.46 100 100 100 100 100 92.37 92.57 100 89.89 80 100 100 100 83.17 100 100 86.3 85.23 100 90.78 100 93.75 100 88.42 100 90 92.05 88.89 100 100 92.71 85.14 78.95 92.31 93.18 95.97 83.33 100 86 92.41 88.51 91.57 100 81.51 100 88.81 85.71 85.06 100 100 100 88.89 90.77 100 89.81 94.68 90.82 100 87.27 81.91 94.44 64.77 81.82 100 90.8 91.25 81.4 91.49 73.33 91.75 100 100 74.51 92.65 78 85.14 100 100 100 100 84.48 95.16 100 80.43 93.59 100 100 100 81.93 82.65 100 89.61 100 85.16 92.91 100 83.95 91.43 90.3 94.78 84.83 84.15 88.54 90.54 72.06 100 100 100 100 89.58 84.27 93.1 89.53 93.64 83.65 82.18 94.57 100 90.41 100 89.26 80.77 100 100 100 100 100 91.95 88.15 74.29 100 74.76 62.5 100 100 84.38 90.24 91.54 100 100 100 100 100 86.21 91.4 80.82 80.85 90.36 100 75.68 85.71 77.27 85.29 87.18 86.49 92.19 100 87.65 90.12 90.67 92.38 100 70.37 86.67 92.05 80.97 -11.08 0.002 0.039269 K cassette MED1 chr17 - chr17:37595447-37596875 chr17:37595447-37596638;chr17:37596772-37596875 chr17:37596639-37596771 100 100 91.84 100 100 100 NA 100 75.61 100 100 100 100 100 100 100 62.16 75.56 100 100 100 100 100 89.09 100 100 100 100 100 100 86.89 100 100 100 100 72.97 100 100 100 73.77 100 100 100 82.98 100 100 NA 100 100 88.52 73.47 82.35 100 86.84 82.19 100 100 85.96 100 100 100 100 100 80 83.33 100 100 100 100 70.24 100 100 100 89.55 88.71 86 83.72 86.54 100 100 100 100 100 100 100 100 100 100 87.67 100 100 85 100 100 100 100 85 82 100 100 100 88.57 100 100 84.75 87.14 100 95.89 90.16 100 100 100 100 NA 100 100 100 82.98 100 100 81.69 100 86.57 90.14 100 86.79 91.89 100 100 100 100 100 100 100 100 100 85.96 100 100 100 100 85.42 100 100 83.33 91.07 100 100 100 100 NA 100 100 100 79.07 100 100 75.76 100 70 100 100 90.91 88.64 82.69 100 87.27 100 100 100 100 100 100 73.37 -26.63 0.000001 0.000071 K alternative_first_exon MED24 chr17 - chr17:38189710-38191369 chr17:38189710-38191168 chr17:38191370-38191602 chr17:38191169-38191225 0 2.63 11.43 25.71 2.5 2.7 1.39 0 2.86 2.7 2.17 0 17.86 3.33 6.52 13.46 5.77 9.23 12.33 1.64 1.43 3.7 5.17 13.54 15.29 2.04 2.7 3.77 4.11 11.76 1.02 0 0 9.88 11.11 24.69 8.24 9.76 8.96 26.25 4.35 2.56 0 2.7 16.07 7.02 6.67 7.52 11.96 11.11 1.96 22.73 15.87 1.64 7.5 14.89 10 0 9.86 4.63 0 3.7 10.87 9.38 6.67 0 16.95 11.25 9.38 24.56 7.25 11.69 22.11 13.75 2.22 0 2.13 14.46 7.69 8.05 15.79 1.52 6.67 6.52 13.04 2.63 2.17 0 1.22 0.96 0 36.36 0 3.57 8.75 0 15.91 7.84 8.79 10.2 10.2 10.2 12.82 12.7 6.93 7.35 9.82 9.88 7.92 13.95 8.75 3.64 7.41 9.68 11.54 13.27 10.11 16.67 2.7 14.63 10.1 1.49 9.64 0 15.49 2.87 14.75 3.33 4.94 3.23 0 0 3.12 10.53 2.04 1.64 11.54 0 1.47 5.56 12.82 2.63 32.65 7.61 2.33 0 11.76 14 NA 0 0 0 4.23 8.16 11.29 1.85 0 8.86 8.6 27.37 7.59 15.79 15.05 4.84 12.82 12.33 8.65 13.75 10.39 14.29 1.54 0 7.13 25.47 18.34 0.000044 0.033777 K alternative_acceptor METT11D1 chr14 + chr14:21458758-21460282 chr14:21458758-21460250 chr14:21460251-21460282 chr14:21460282-21460283 41.03 65.45 36.73 36 28.3 41.86 37.5 32.5 36.07 40 35.96 NA 42.86 45.33 21.62 34.48 44.44 34.12 26.39 14.06 33.75 23.53 32.5 27.78 24.69 33.33 29.17 30.26 30.91 35.59 28.38 38 28.81 28.44 21.54 14.06 31.58 41.9 31.25 13.76 37.5 48.39 37.97 36.92 49.02 31.03 38.82 30.51 37.5 36.9 37.04 9.2 40.68 30.51 56.86 49.02 29.17 52.05 31.25 42.72 31.75 49.06 35.29 36.67 33.73 48.57 44.12 34.21 39.74 25 32.18 40.54 51.47 38.46 37.76 36.78 41.46 35.71 47.76 43.24 31.58 46.03 52.63 34.65 35.8 47.92 39.44 43.62 44.62 26 52.24 14 35.82 31.58 34.07 20.69 44.26 46.72 45.77 53.12 34.43 38.4 26.96 42.62 43.36 51.09 45.04 38.21 38.46 57.89 55.32 42.7 65.05 27.94 39.51 43.1 38.81 31.52 44.68 53.68 46.15 34.45 58.75 39.81 36.84 42.36 32.61 29.73 28.81 58.97 29.07 0 18.03 58.82 25 45.83 40 44.19 23.38 44.12 34.62 39.39 48.72 46.24 24.69 35.38 38.64 44.44 16.67 100 0 39.13 42.64 68.54 25 50 48.08 27.54 40 16.33 41.46 42.86 34.67 48.84 55.26 31.18 34.21 29.17 32.39 38.81 44.9 27.78 37.88 14.03 -23.85 0.000083 0.006945 N mutually_exclusive MFF chr2 + chr2:228205097-228207460,chr2:228207536-228220392;chr2:228205097-228211941,chr2:228212101-228220392 chr2:228205097-228217229,chr2:228217290-228220392 chr2:228207461-228207535;chr2:228211942-228212100 chr2:228217230-228217289 82.61 NA 80 87.5 57.14 78.57 48.65 NA 16.13 87.5 NA NA NA NA 55.56 91.67 30 58.33 51.43 63.64 NA 72 NA 86.67 NA 9.09 NA NA 40 37.5 69.23 43.48 NA NA 57.89 0 42.86 91.67 27.78 25 NA 36.67 50 80 NA 94.44 58.33 65.52 71.43 54.17 56.67 0 NA 77.78 58.82 61.9 68.42 92.86 92.86 70 76.92 NA 65 50 46.15 NA 90.48 75 90 NA 50 NA 60 47.62 NA 53.33 37.5 38.24 0 66.67 32 80 83.33 80 NA 78.57 NA 77.27 NA 52.63 NA 9.09 80 NA 22.22 NA 90.91 42.86 81.25 NA 94.74 83.33 50 70.59 42.5 55.56 95.24 69.23 55.56 72.73 46.67 60 91.67 NA 57.14 35.29 34.78 33.33 61.54 65.38 71.43 46.67 90 42.86 95.65 92.31 61.54 NA 42.42 64.29 77.27 87.5 87.5 NA NA 58.33 NA 53.85 81.25 NA 38.1 78.57 68.18 41.18 NA 44.44 NA 91.67 NA NA NA 60 57.14 65 76.92 60 73.91 61.54 48.28 0 58.82 87.5 80 40.91 NA 86.67 38.89 NA 41.94 NA 76.92 47.37 63.64 0 -63.64 0.000227 0.01128 N cassette MITD1 chr2 - chr2:99787116-99787972 chr2:99787116-99787805;chr2:99787893-99787972 chr2:99787806-99787892 100 89.33 100 67.65 86.9 100 100 100 89.58 100 100 100 100 100 100 100 54.84 100 93.59 100 100 100 100 89.29 100 100 100 100 100 89.58 90.38 85.96 100 82.69 100 80 100 92.63 88.89 71.64 100 100 100 100 100 100 100 90.38 87.5 88.89 83.33 100 100 88.89 78.05 84.31 100 89.58 100 100 87.5 100 100 88.68 100 100 84.31 100 90.14 88.46 87.88 100 100 100 94.17 100 100 100 100 100 88.37 100 75 100 100 83.82 100 90.16 100 90.36 100 79.17 100 100 100 100 85.45 41.43 87.32 100 100 92.19 100 100 100 89.36 100 100 90.77 100 100 100 87.32 100 100 100 100 100 100 100 90.57 93.58 88.04 91 100 87.18 100 100 100 83.72 100 100 100 100 100 100 100 100 100 61.54 100 100 100 100 100 100 84.13 89.8 80 100 100 100 93.67 88.76 100 76.19 100 84 100 79.59 88.89 92.11 90.48 100 100 100 100 100 100 100 100 100 100 79.8 -20.2 0.000902 0.021715 N alternative_acceptor MNAT1 chr14 + chr14:61346554-61435276 chr14:61346554-61434946 chr14:61434947-61435276 chr14:61435276-61435277 100 100 100 100 100 66.67 52.94 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 87.18 100 78.26 100 69.7 100 100 100 79.31 100 100 100 100 100 100 100 100 100 100 100 100 100 55.56 100 100 100 100 100 100 100 100 100 68 100 100 100 NA 100 100 100 100 100 80 100 NA 100 100 100 NA 100 100 100 100 77.5 100 83.33 100 100 100 100 100 NA 100 100 61.76 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 61.11 100 100 100 85.29 100 100 100 100 100 100 100 100 100 69.7 -30.3 0.000007 0.000716 K cassette MR1 chr1 + chr1:181019423-181022708 chr1:181019423-181021370;chr1:181021647-181022708 chr1:181021371-181021646 100 38.1 44.07 37.5 29.55 18.18 18.75 24.56 33.33 40.38 51.65 100 45 35.44 30 58.54 24 52.5 33.33 68.97 42.05 38 35.29 39.29 35.71 20.51 39.29 38.1 41.41 44.44 49.21 35.59 35.71 35.9 33.33 24.32 43.64 36.92 38 24.44 34.48 35.14 48.35 25.37 31.37 55 52.63 39.06 47.73 50 55.13 29.55 47.62 44.44 38.71 27.59 24.24 50.94 36.76 40.43 34 37.84 39.13 40.68 43.28 44 30.95 33.33 54.84 21.62 43.42 38.89 54.24 34 44.12 38.55 37.21 50.91 45 37.74 37.5 40.62 50 30.59 35.14 32.61 55.81 43.9 37.93 44.44 41.3 22.22 33.87 42.42 40.96 43.75 27.27 47.76 44.44 35.19 32.17 30 41.86 40.48 30.77 34.55 30 23.61 29.79 37.21 48 44.07 53.85 39.62 37.97 37.23 36.25 23.64 54.55 50 31.15 28 33.33 32.26 43.64 36.67 48.28 28.95 37.14 31.03 35.71 37.14 43.88 44.19 48.94 33.93 54.17 41.67 32.5 25 27.27 45 31.94 37.74 22.86 26.94 23.81 40 NA 50.94 18.52 40.74 26.76 26.47 33.33 48.15 26.09 29.41 37.5 27.27 52.17 35.48 46.67 21.21 35.71 30.61 41.94 38.46 38.81 30.43 26.92 37.84 37.84 24.38 -13.46 0.000443 0.013931 K cassette MRPL33 chr2 + chr2:27995560-28002299 chr2:27995560-27997290;chr2:27997398-28002299 chr2:27997291-27997397 40.24 41.08 41.38 11.11 44.25 39.87 54.3 60.31 47.73 41.51 52.04 56.28 59.42 53.57 54.18 68.18 33.85 47.37 58.21 64.96 66.38 39.24 67.61 65.31 54.27 28.09 48.41 57.31 59.29 67.57 63.48 48.74 58.33 50.3 57.47 42.37 61.68 56.25 62.42 31.17 47.67 48.28 65.44 61.94 46.72 45.88 55.56 71.74 55.13 65.52 53.52 41.64 52.5 44.39 36.76 50.3 62.5 72.88 64.06 64.58 63.89 52.24 55.81 49.55 54.13 54.93 56.14 58.21 57.58 31.71 59.41 37.93 53.77 56.52 53.09 58.86 61.76 62.18 65.79 57.47 65.43 65.45 50.55 61.61 67.39 45.45 52.52 44.78 63.33 63.23 48.5 35 60.71 62.16 51.65 63.11 23.4 50.96 53.33 68.35 52.27 52.07 65.68 65.08 61.9 36.73 51 60.53 56.75 34.44 56.91 52.17 29.33 40.5 40.58 45.71 47.3 48.68 52.76 71.93 59.32 55.56 31.88 56.86 61.9 58.24 65.52 64.52 50.12 35.29 59.16 46.67 56.09 62.96 60.83 63.44 54.88 37.27 62.37 50.64 24.14 66.67 52.86 62.07 57.14 64.52 65.15 42.03 40.56 61.81 53.46 60 71.79 45.49 52.04 68.22 52.11 50 54.55 44.55 56.41 49.73 56.04 52.85 20.31 39.81 67.21 64.56 56.25 44.59 57.65 59.23 55.81 38.32 -17.49 0.000672 0.017353 K cassette MRPL52 chr14 + chr14:23299464-23303380 chr14:23299464-23302626;chr14:23302692-23303380 chr14:23302627-23302691 100 89.09 100 100 100 100 95.13 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.74 100 92.62 100 100 100 100 100 100 100 100 100 89.09 91.94 100 100 85.19 100 100 100 100 100 90.32 90.11 100 100 100 100 89.43 100 100 100 100 100 100 100 100 100 86.84 90.91 100 90.38 100 90.91 100 89.47 83.33 100 100 100 100 100 100 100 100 100 91.26 100 100 100 100 100 82.81 100 100 83.05 93.21 100 91.8 100 100 91.43 100 100 81.69 92.75 94.33 95.33 100 94.02 100 100 90.32 93.33 93.1 100 100 100 93.58 100 100 100 100 100 95.31 100 87.18 88.71 100 89.01 100 100 89.47 100 100 88.54 100 91.07 100 100 100 100 100 100 100 92.62 78.05 100 100 100 100 100 100 100 100 96.21 100 100 100 100 100 100 100 100 100 100 87.1 100 100 88.46 100 100 100 100 85.19 100 100 90.38 100 100 88.09 -11.91 0.000003 0.000237 N cassette MRRF chr9 + chr9:125047567-125054027 chr9:125047567-125048317;chr9:125048446-125054027 chr9:125048318-125048445 56.25 47.62 47.22 100 53.06 66.67 47.62 34.78 75 38.18 38 NA 56.25 51.35 46 63.64 56.14 61.7 37.5 21.95 39.39 100 27.78 35.59 38.89 30.77 24.14 40.74 77.14 45.71 57.58 48.89 100 34.69 30.3 28.26 60.42 55 51.11 30.56 61.54 100 40 43.64 64.1 48.15 31.25 56.36 42.25 61.22 39.66 30.53 56.41 50 62.96 66.67 25 73.08 54.55 60.87 62.5 76.19 40 51.52 46.48 60.47 61.22 60.47 36.07 42.59 62.5 62.5 60 63.27 48.08 44.44 61.54 23.53 75.76 49.02 57.69 65.79 81.48 42.11 62.22 40 67.74 100 49.25 37.31 100 34.21 63.41 52.78 54.05 57.14 100 49.33 67.92 100 44 51.52 35 47.62 74.07 53.45 62.5 44.26 58.14 50 62.5 66.67 82.76 100 48.72 67.31 45.9 47.06 45.65 65.52 57.14 54.05 76.6 64.15 49.18 54.72 35.71 100 35.42 100 42.42 31.37 37.14 58.33 34.48 13.04 54.17 52.38 40.35 51.61 55 35.85 52.5 48.05 37.78 43.4 54.17 50 NA 20.83 NA 24.14 50.98 68.63 48.48 59.26 55.36 47.06 60 44.44 40.91 100 45.76 61.11 70.27 59.46 38.46 52.94 47.37 70.59 58.54 50 52.64 32.38 -20.26 0.001985 0.039256 N cassette MTA1 chr14 + chr14:105905077-105916394;chr14:105911849-105916394 chr14:105911849-105915695,chr14:105905077-105915695;chr14:105915747-105916394 chr14:105915696-105915746 71.43 84 64.29 100 69.05 71.72 63.68 68.67 69.62 69.14 65.38 NA 61.03 49.06 58.54 79.41 40 62.07 67.59 73.08 80 77.08 57.53 73.23 72.17 100 58.93 64 65.62 71.21 75.23 60.61 79.59 68.82 70.83 52.44 69.18 67.36 67.71 38.06 65.08 55.74 59.79 62.12 59.52 65.08 70.37 58.47 66.04 58.28 68.93 60.87 73.63 54.37 94.44 70.09 54.76 72.22 72.58 66 63.12 55.1 53.33 66.67 70.31 64.04 65.03 66.67 59.38 53.26 58.33 70.83 56.52 65.66 62.07 67.86 62.92 54.95 66.36 68.31 65.98 58.06 53.85 63.04 62.04 91.57 68.67 76.67 70.19 71.7 62.75 37.5 64.37 62.5 64.84 60.61 75 30.67 61.58 67.28 81.03 70.59 71.53 55.79 55.86 64.5 67.16 73.08 72.73 67.44 79.69 46.9 93.64 49.23 50.41 54.17 68.32 66.49 75 66.93 65.9 47.41 86.41 48.63 58.24 51.79 67.95 73.08 75.82 71.43 72.04 70.87 65.79 50 44.64 53.93 75 50.79 51.72 100 76.92 55.41 100 67.41 63.51 59.02 57.14 65.91 53.25 100 65.75 56.52 58.82 64.38 67.65 62.65 71.43 70.83 66.2 47.37 64 53.42 66.88 68.99 100 73.68 69.1 57.35 53.45 72.41 46.61 65.18 66.28 49.91 -16.38 0.000466 0.014107 K alternative_acceptor MTA1 chr14 + chr14:105930485-105930799 chr14:105930485-105930752 chr14:105930753-105930799 chr14:105930799-105930800 55.41 70.24 68.75 87.5 61.19 60.55 49.68 61.26 67.09 79.84 78.08 100 65.19 72.31 75 68.18 55.73 72.22 70.68 84.75 62.3 77.05 68.85 67.41 62.6 75.7 64.29 65.83 63.96 61.11 71.43 74.55 63.06 57.62 85.19 45.68 63.49 63.58 63.48 50.39 48.98 70.31 70.33 81.72 53.92 69.4 69.48 74.22 70.59 67.09 78.95 16 65.44 67.52 79.44 65.25 68.49 65.55 62.59 73.15 66.09 63.22 70.83 74.51 68.99 51.15 57.95 69.23 62.28 28.57 60.87 65.44 72.44 66.67 58.33 70.68 64.77 64.35 67.91 62.75 70.83 68.97 72.73 61.7 61.9 82.76 68.32 73.12 57.5 59.63 65.96 33.96 62.62 75.68 79.37 80.77 70.91 62.37 61.25 64.21 62.68 65.04 67.81 71.77 73.97 68.67 72.29 63.06 67.97 75.93 67.59 71.3 74.4 78.81 74.44 67.89 74.38 51.54 61.76 70.29 72.02 60.5 69 65.62 68.52 73.44 68.18 72.22 62.37 100 76.47 86.76 85.96 72.6 72.88 68.49 62.79 54.29 78.99 73.08 69.39 70.45 89.02 65.69 71.05 61.9 65.52 74 68.22 100 84.38 65.91 62.7 54.09 65.62 69.77 59.2 48.51 75.36 40.96 67.65 64.65 72.15 74.59 74.36 69.23 75.56 77.27 86.59 65.81 62.02 74.53 68.49 37.46 -31.03 0.000037 0.003494 K cassette MTRR chr5 + chr5:7871037-7875370 chr5:7871037-7873485;chr5:7873640-7875370 chr5:7873486-7873639 NA 37.5 24.29 28.99 30.23 NA 21.74 31.17 39.53 17.24 50 NA 36.67 30.49 39.02 28 15.52 19.15 31.82 100 34.29 37.5 21.43 33.33 48 26.67 12 41.18 30 35.42 45 36.67 3.23 26.19 50 15 26.53 31.58 13.89 13.89 23.08 33.33 42.22 48.15 10 26.19 30 48.98 33.33 48.57 50 21.43 39.13 28.57 35.14 30.77 16.22 34.78 35.14 26.09 36.84 34.29 34.48 25.53 27.08 21.05 36.59 23.53 22.22 13.79 29.63 28.57 42.11 27.03 26.67 24.39 26.67 27.27 33.33 27.71 28 31.03 62.96 25.81 25 36 24.53 39.02 16.67 48.85 42.11 13.89 43.48 20.51 26.53 20 35.48 36 30.43 40.43 38.1 31.43 43.59 37.04 23.33 45.71 21.13 32 48.98 42.11 28.33 46.77 32.05 NA 28.12 38.1 45.24 37.33 15.38 25.37 29.79 22.64 36.36 29.69 37.14 48.57 37.93 29.17 35.42 25 43.48 NA 50 37.84 24.39 42.22 26.47 44.12 48.94 28.12 33.33 56.76 45.45 30 37.5 37.7 23.81 50 5.56 NA NA 41.67 38.18 41.67 22.22 26.67 37.84 28.57 55.1 22.22 29.17 20 46.43 52.63 25.58 33.33 34.21 37.5 42.86 28.12 18.75 46.67 32.05 14.45 -17.6 0.000244 0.009502 K cassette MUM1 chr19 + chr19:1358464-1360134 chr19:1358464-1358586;chr19:1358700-1360134 chr19:1358587-1358699 4.71 15.38 8.33 7.14 12.28 6.9 6.25 6.25 11.54 9.21 41.18 NA 12.9 12.82 15.38 13.64 7.55 2 14.61 15.79 6.67 5 11.76 13.79 13.33 27.27 19.35 18 6.98 9.68 12.82 3.33 23.81 14.66 5.56 18.18 22.95 16.67 14.29 28.77 10 4.55 7.14 4.88 16.67 18 18.87 14.29 26.56 17.65 11.32 56.14 14.29 11.11 10 4.35 5 14 6.52 17.46 7.69 33.33 17.39 8 12.2 14.61 7.81 15.15 20 30.43 18 8.33 38.89 6.98 18.52 2.44 10.34 13.79 7.89 16 2.33 3.51 8.51 11.11 10.98 20.9 9.3 7.14 11.4 23.4 13.33 53.57 6.25 7.14 11.63 14.29 10 22.81 44.32 17.39 5.88 13.73 11.32 22.22 7.59 9.09 17.27 13.33 9.68 20.83 25 15 10.71 14.29 18.18 15.38 18.31 13.43 5.88 11.83 4.84 10.2 11.32 4.81 21.05 19.23 14.29 12.5 11.43 10.53 6.38 16.67 20.51 10.98 6.25 10 12 21.43 27.72 NA 14.71 5.08 5 14.81 12.82 17.95 7.32 7.14 NA 43.75 NA 26.67 6.67 18.37 6.67 4.76 8.16 17.24 29.27 39.13 15.38 7.61 17.07 7.41 9.62 5.56 10.61 9.26 10.2 13.04 9.09 7.69 11.83 34.78 22.95 0.000162 0.007027 N cassette MYO15B chr17 + chr17:73602103-73606246 chr17:73602103-73603013;chr17:73603085-73606246 chr17:73603014-73603084 53.7 64 46.15 56.41 81.82 77.14 40.1 50 41.82 100 43.42 42.11 67.2 74.24 39.53 74.29 13.38 77.87 51.47 60 24.44 45.83 29.17 36.36 84.72 28 40 26.6 44.12 41.24 20 65.91 32.14 28.11 67.65 19.05 45.73 52.54 36.44 28.05 24.82 66.67 25.24 46.81 73.53 100 25 37.5 43.75 35.64 48 16.28 54.55 48.65 50.56 48.88 53.12 28.57 29.11 63.16 36.07 47.65 42.62 52.11 30.77 42.53 46.83 64.04 41.67 33.72 16.81 40 68.85 45.29 35.4 25.41 45.68 50.7 31.71 39.67 48.39 62.35 63.41 41.73 47.27 64.58 9.52 75.81 59.43 46.67 64.29 30.43 43.4 60 24 56.52 70.83 12.35 47.34 26.96 53.85 49.4 24.77 47.76 43.61 61.74 49.69 64.75 39.88 80.49 63.96 37.5 56.5 51.28 52.63 70.76 50.75 25.81 25.19 62.96 76.35 38.57 42.73 23.08 43.75 47.65 24.29 48.28 31.39 76.79 60 48.39 27.27 50 51.02 20 44.87 32.91 58.14 50 82.72 68.75 73.53 38.97 47.62 38.16 39.71 44.44 NA 71.11 19.05 42.86 33.33 51.52 38.41 26.49 63.39 25.53 53.57 21.37 38.57 43.48 71.72 27.72 52.68 76.38 49.47 38.89 55.93 47.46 33.33 33.06 47.05 24.71 -22.34 0.000921 0.021995 N cassette N4BP2 chr4 + chr4:40099190-40103694;chr4:40100317-40103694 chr4:40099190-40101655,chr4:40100317-40101655;chr4:40101747-40103694 chr4:40101656-40101746 NA 12 22.73 35.59 30 NA NA 33.33 NA NA 31.25 NA 26.67 10 NA 46.15 33.33 35.29 27.78 NA 16.67 NA NA 43.75 23.08 NA NA 30 33.33 27.27 23.08 24.24 NA NA 17.39 64.29 NA 31.43 21.05 100 33.33 15.49 16.67 36.36 NA 23.53 NA 40 27.27 16.67 15.79 57.14 NA 5.56 NA NA NA NA 23.81 36.36 18.18 12.5 30 14.81 18.75 50 26.47 30.43 25 47.62 21.43 27.03 36 33.33 28.57 31.58 28.57 15.38 26.09 32 27.78 36.36 28.57 NA 33.33 31.03 26.09 9.09 36.67 28.57 NA 100 7.14 NA 12.5 NA 17.39 30 15.38 33.33 33.33 8.33 NA NA 44.44 43.48 20 25 NA 27.78 0 41.67 10 NA NA 31.58 32.14 30 NA 48 19.35 18.75 4.76 28.12 23.53 NA NA 34.78 NA 3.57 NA 28.57 NA 53.57 11.11 NA 34.29 31.25 NA NA 30.77 30 NA 16.67 11.76 NA 23.08 16.67 NA NA NA NA 31.03 21.43 43.75 37.5 21.88 35 41.67 76 16.67 50 26.67 35.29 24 NA 28.57 25 30.77 NA 26.32 NA 27.78 70.15 42.37 0.000048 0.002751 N cassette N6AMT2 chr13 - chr13:21303356-21331593 chr13:21303356-21305979;chr13:21306261-21331593 chr13:21305980-21306260 100 100 100 NA 100 77.27 NA 100 100 100 100 NA 100 47.62 100 100 100 100 100 100 100 100 100 100 100 100 100 100 64.71 58.82 100 100 100 100 NA 64.29 100 100 78.57 60.53 100 100 100 100 100 70 67.65 75.93 100 100 81.63 74.42 75 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 69.23 100 64.71 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 83.72 100 88.31 NA 100 100 100 100 NA NA 66.67 100 100 77.97 100 73.53 100 100 100 100 79.07 100 100 100 81.08 NA NA 69.57 100 100 100 100 100 85.71 79.49 NA 100 100 100 61.11 100 74.07 NA 100 100 57.69 100 73.68 68.29 100 NA 100 NA 75 42.5 100 100 100 100 100 100 100 100 100 100 100 100 80 100 100 NA 100 69.57 80 100 100 100 61.9 100 100 86.49 100 100 100 100 100 69.4 -30.6 0.000163 0.007046 N coord_cassette N6AMT2 chr13 - chr13:21303356-21331593 chr13:21303356-21305979;chr13:21306261-21311861;chr13:21311945-21331593 chr13:21305980-21306260;chr13:21311862-21311944 NA NA 100 NA 100 73.68 NA 100 100 100 100 NA 100 31.25 100 NA NA 100 100 100 NA NA 100 100 100 NA 100 100 62.5 41.67 100 100 NA NA NA 66.67 100 100 62.5 59.46 NA NA 100 100 100 66.67 63.33 69.05 100 NA 71.88 71.79 72 100 NA NA NA 100 100 100 NA 100 NA 100 100 100 100 100 100 65.22 100 50 100 100 100 100 NA 100 100 100 NA 100 NA NA 100 100 NA 78.79 100 85 NA NA 100 100 100 NA NA 62.5 100 100 76.36 100 70 NA 100 100 100 71.88 NA NA 100 78.12 NA NA 56.25 100 100 100 100 100 83.87 77.14 NA 100 100 100 63.16 100 73.08 NA 100 NA 37.14 NA 54.55 70.45 100 NA 100 NA 72 25.81 NA 100 100 100 100 100 100 NA 100 NA 100 100 78.26 NA 100 NA 100 65 77.27 100 100 100 27.27 100 100 82.76 100 100 NA NA 100 65.22 -34.78 0.000305 0.013342 N cassette NARG1L chr13 + chr13:41905506-41929279;chr13:41905506-41932439 chr13:41905506-41910785;chr13:41910893-41929279,chr13:41910893-41932439 chr13:41910786-41910892 NA 100 100 100 100 NA 71.43 100 80.77 100 100 NA 100 100 100 73.53 100 100 73.91 NA 100 NA 100 100 NA 100 100 100 100 65 100 100 100 NA 100 NA 100 100 100 65.22 NA 100 100 100 100 100 100 100 100 100 100 NA 100 100 75 100 100 100 100 82.14 100 70.83 100 100 73.91 100 78.26 100 100 100 71.43 100 81.25 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 61.54 100 100 100 100 100 66.67 100 100 100 81.08 NA 100 100 100 100 100 79.31 100 100 100 80 NA 68.75 100 100 100 100 86.11 100 100 100 100 82.14 81.48 100 100 100 100 100 100 100 100 100 100 100 77.42 100 NA 100 100 NA 100 100 100 100 100 100 NA NA NA 100 100 100 78.26 100 75 80 74.19 75 100 100 100 100 100 100 66.67 100 100 100 NA 100 69.7 -30.3 0.001039 0.02406 K cassette NBPF8 chr1 + chr1:144598781-144606368 chr1:144598781-144604477;chr1:144604509-144606368 chr1:144604478-144604508 60 28.57 41.18 30.77 50 51.61 30 52.63 31.25 66.67 40 100 45 60 21.43 48.15 50 54.55 41.67 NA 43.18 51.72 51.11 56 42.59 40.58 32.35 65.12 41.94 42.11 48.39 78.38 42.86 53.49 21.43 44.12 41.25 40.74 45 58.82 52.63 68.18 46.88 61.54 56.52 23.53 23.53 60 43.4 35.71 41.79 61.54 50 51.91 60 59.38 40 58.21 NA 46.6 52.94 40.54 56.52 57.78 43.48 41.3 44.12 23.53 32 63.64 55.17 NA 53.33 51.11 46.67 28.57 58.14 52.54 45.71 36.36 48.57 61.9 42.86 45.65 53.79 31.51 100 37.93 35.48 54.76 18.18 76.32 26.47 41.18 36 39.53 51.11 46.05 37.63 25.53 40.54 56 48.39 52.5 34.78 33.33 43.59 52.38 53.57 26.92 32.81 27.54 46.15 NA 39.39 53.62 22.58 34.62 26.32 44.72 36.67 56.52 38.78 48.81 41.46 25.93 NA NA 47.83 33.33 48 51.11 38.89 100 64.29 41.67 34.69 54.55 60 33.33 33.33 36 25 36.36 37.5 46.43 56.25 50 NA 0 NA 39.13 42.35 37.5 42.55 35.48 42.86 54.17 46.73 64.95 54.55 55.32 33.33 48.28 15.38 60.98 32.5 41.18 45.71 37.14 39.02 NA 43.48 62.59 19.11 0.002215 0.042495 K cassette NBR2 chr17 + chr17:41277788-41290673 chr17:41277788-41283224;chr17:41283288-41290673 chr17:41283225-41283287 100 100 100 100 100 100 100 100 NA 100 100 100 100 78.26 100 100 100 100 100 NA 100 NA 100 100 100 100 NA 100 100 100 100 100 100 100 100 63.16 100 100 100 64.86 NA NA 100 82.14 NA 100 100 65.22 78.38 69.77 NA 75 100 100 NA NA NA 100 85.71 74.19 100 100 100 100 100 73.68 72.41 72.73 72.73 72.41 100 100 82.89 100 78.38 100 100 NA 84.21 85.11 69.7 100 100 100 75.86 NA 100 100 100 83.33 100 NA 100 100 100 100 100 100 81.25 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 80 100 100 100 100 65.91 100 NA 100 84.38 NA 100 100 100 100 100 100 100 78.05 NA 100 100 100 100 NA 100 100 NA 69.44 100 100 72.41 100 75 100 NA 100 100 100 100 100 100 100 100 68 100 100 100 100 NA 100 82.35 66.67 100 100 66.67 100 100 68 -32 0.000002 0.000123 N cassette NCAPD3 chr11 - chr11:134078846-134079206 chr11:134078846-134079038;chr11:134079101-134079206 chr11:134079039-134079100 NA 100 100 100 100 100 NA 100 100 100 100 NA 100 100 100 100 100 100 100 100 92.19 100 76.74 100 85.71 100 100 92.31 100 100 92 100 100 100 100 85.11 100 100 89.55 82 82.76 74.03 100 100 100 100 100 90.53 100 88.46 100 72.92 100 100 100 100 62.86 100 100 100 87.72 80.65 85.42 90.32 88.46 88.1 100 88.52 100 86.11 100 90 100 87.88 100 100 100 84.82 76.6 100 100 100 100 79.25 100 100 77.27 100 100 100 100 84.04 100 70.21 100 100 100 91.14 100 84.62 100 100 100 89.13 84.48 100 100 87.72 86.36 83.64 100 100 100 100 93.59 89.36 100 100 100 94.16 100 100 100 100 100 100 100 100 100 77.78 100 100 100 100 100 100 89.06 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 79.55 86.67 90.74 83.33 91.67 84.85 84.71 100 100 77.78 100 100 92.86 100 92.86 92 100 100 100 84.44 -15.56 0.000036 0.002188 K alternative_acceptor NCAPG2 chr7 - chr7:158468309-158472651 chr7:158468349-158472651 chr7:158468309-158468348 chr7:158468308-158468309 chr7:158472652-158472777;chr7:158468169-158468308 NA 100 100 100 75.61 NA NA 100 84.91 NA 90.1 NA 100 100 100 NA 67.35 100 76.32 100 100 100 100 87.1 100 100 100 100 85.71 100 100 100 100 100 100 58.82 77.78 83.33 89.13 66.67 100 100 100 100 76.79 100 100 100 100 100 91.74 78.38 100 90 100 100 100 100 100 84.75 100 100 100 100 100 100 73.08 80 84.78 62.5 88.46 100 77.27 100 100 89.58 NA 100 100 100 100 100 88 100 84.48 NA 100 100 86 88.75 100 62.3 100 100 100 100 100 71.43 84.31 100 75 100 80.43 100 100 100 93.24 100 77.5 70.59 66.67 68.18 100 100 100 83.87 82.05 73.53 100 100 100 78.69 88 100 100 100 100 100 100 83.02 100 100 100 100 100 100 79.52 100 82.05 NA 100 84.62 100 88.1 81.16 68.42 100 100 NA 77.78 NA NA 100 70.45 100 86.76 83.33 76 100 60.53 89.13 NA 100 100 100 100 100 100 100 100 100 100 100 62.4 -37.6 0.000004 0.000433 N cassette NCOA2 chr8 - chr8:71053635-71068205;chr8:71053635-71060507 chr8:71053635-71056876;chr8:71057084-71060507,chr8:71057084-71068205 chr8:71056877-71057083 100 84.29 100 100 100 NA 57.14 100 86.96 77.55 100 100 86.36 80.3 100 89.33 75.21 90.53 85.19 100 81.71 100 100 84 79.17 100 100 81.13 75 86.75 85.26 100 100 100 100 78 100 100 100 83.33 73.17 83.87 85.25 100 100 100 100 81.52 100 90.54 85.96 71.7 100 89.8 84.29 100 100 84.72 87.72 83.82 82.67 100 85.71 87.69 84.85 100 100 86.36 90 84.44 82.81 100 100 82.42 84.38 86.21 80.56 92.11 87.93 100 100 84.91 87.01 77.08 86.96 100 100 100 85.07 100 100 77.91 85.29 83.33 77.11 86.96 85 87.5 85.71 100 89.36 87.5 100 83.33 80.82 81.4 82.76 80.95 76.79 100 100 85.71 83.91 100 100 83.95 100 92.78 100 100 81.25 80.77 83.65 89.23 89.23 83.33 100 100 87.72 88.57 100 100 100 100 100 100 100 100 76.56 100 100 100 100 78.85 100 84.15 100 100 NA 100 100 84.13 90 100 100 80.6 90 77.5 90.74 70.45 80 100 84.75 100 82.98 100 92.54 84.09 86.36 100 100 78.57 90 77.95 -12.05 0.000457 0.014065 K cassette NCOR2 chr12 - chr12:124857157-124862782 chr12:124857157-124858958;chr12:124859010-124862782 chr12:124858959-124859009 0 38.71 25 22.45 43.33 31.37 17.82 31.03 31.19 62 29.82 50.79 35.96 27.78 39.13 63.53 25.64 46.03 38 44 36.05 42.86 41.18 57.43 46.15 28.45 15.52 35.9 32.89 38.68 48.81 40.3 33.33 46.43 27.14 61.45 39.29 36.49 28.75 58.54 31.37 52.63 30 29.63 38.18 49.33 29.69 46.67 30.36 30.12 30.51 44.93 32 41.18 30.69 35.43 31.71 40.43 42.37 36.9 31.82 19.05 46.43 34.85 41.82 35 45.9 44.3 55.1 32.35 36.89 55.56 21.67 20.28 39.53 30.77 41.46 38.18 25.58 42.86 28.57 20.83 26.47 31.03 36.9 32.14 32.81 43.75 35.64 46.97 20.45 57.14 41.38 48 36.17 22.58 30.43 40.48 27.62 54.81 44.07 33.33 39.39 30.77 30.77 26.62 41.82 41.54 37.86 43.75 42.86 35.62 33.82 20.83 27.27 44.55 30 31.43 26.32 45.45 41.74 28.38 23.48 18.18 29.73 32 32.2 NA 34.23 30.3 32.61 28.57 56.67 23.81 22 49.09 27.12 28.57 26.19 33.33 29.41 25.93 33.33 40.61 NA 36.67 NA 39.66 29.17 40.62 NA 45.45 38.6 31.25 36.84 32.79 32.69 25.71 43.86 57.33 31.91 28 44.07 44.9 31.67 56.76 38.16 43.59 29.85 33.33 23.4 30 34.85 57.23 22.38 0.002259 0.042935 K cassette NFYC chr1 + chr1:41232376-41235027 chr1:41232376-41232589;chr1:41232647-41235027 chr1:41232590-41232646 2.17 3 10.34 16.98 9.52 25.53 33.33 0 4.76 2 10.87 0 8.43 5.68 6.19 7.22 9.01 3.75 5.06 0 4.17 1.64 6.86 4.38 9.09 11.76 6.02 15.71 8.18 3.96 6.42 0 11.11 8.97 9.78 8.54 9.18 7.59 8.33 45.71 18 4.08 3.08 9.76 10.34 2.38 7.69 7.2 2.97 2.97 5.3 20.48 12.36 15.85 3.09 5.31 20.37 5.68 3.75 8.09 13.7 16.18 13.33 10.48 8.26 14.29 3.28 13.54 8.53 15.71 6.84 8.33 4.9 14.29 8.54 8.87 14.29 9.52 0 4.5 15.73 10.2 1.12 17.91 2.41 1.33 3.77 11.34 14.14 4.65 3.64 22.58 0 2.63 7.69 8.06 2.56 11.97 3.09 10.91 7.79 14.4 7.94 14.89 17.65 2.35 7.51 9.92 12.44 4.6 5.26 6.99 11.11 1.69 3.39 9.71 4.7 10.69 8.51 9.09 13.04 11.76 8.16 15.75 10.87 8.1 7.55 10.26 6.35 3.12 2.2 2.67 2.44 10.81 5.88 0.86 3.92 11.67 5.63 14 1.45 0 16.67 9.2 6.17 8.81 12.5 8.82 6.35 4.9 2.7 7.34 5.88 9.8 11.34 11.96 5.63 7.34 5.62 12.3 7.37 5.05 5.04 9.18 9.09 8.54 5 6.96 8.48 7.41 9.59 9.65 7.79 18.09 10.3 0.001338 0.029085 K cassette NGLY1 chr3 - chr3:25761127-25770623 chr3:25761127-25761504;chr3:25761683-25770623 chr3:25761505-25761682 81.38 78.9 91.97 81.71 82.67 75.22 70.65 77.12 70.19 89.51 81.82 100 86.46 78.38 89.5 100 87.64 90.62 87.77 83.08 78.12 75.61 86 88.5 72.28 78.67 73.53 77.39 85.96 87.5 88.6 89.21 67.2 65.9 78.14 67.27 88.7 79.63 78.23 67.8 73.33 84.83 80 79.04 76.55 75.27 81.82 84.18 79.63 80.83 90.85 68.54 82.47 86.1 83.33 72.09 87.67 90.76 87.74 100 80.81 86.57 91.53 88.24 84.35 84.96 91.67 81.31 89.21 78.69 80.39 100 91.67 89.58 84.52 93.75 85.29 78.41 90.48 83.57 94.12 89.52 90 77.27 86.11 83.51 100 79.31 85.37 83.33 100 59.74 86.24 82.46 80 79.59 79.38 53.8 90.36 100 84.42 79.67 79.14 85.12 87.77 83.45 86.13 75 83.05 100 89.71 73.24 80.18 100 94.53 90.57 77.36 87.5 86.54 94.55 83.21 91.53 84.55 86.63 81.94 100 76.39 88.04 66 80.39 78.8 100 86.47 84.48 82.69 81.4 90.48 84.62 80.83 100 79.12 74.86 100 89.52 85.85 79.55 82.61 80 71.19 72.79 100 78.57 81.29 88.68 80.16 89.19 89.31 70.89 83.33 81.94 73.83 83.14 89.34 77.78 84.62 87.64 80.58 84.04 82.25 82.02 77.78 90.79 84.04 68.17 -15.87 0.001418 0.030431 N cassette NIN chr14 - chr14:51230683-51233497 chr14:51230683-51233024;chr14:51233115-51233497 chr14:51233025-51233114 100 81.32 91.43 84.21 100 NA 100 90.67 77.78 100 92.31 100 100 100 100 100 85.15 86.84 91.6 100 94.05 100 90.57 87.65 100 83.33 80.46 100 89.55 100 81.71 91.25 100 100 81.58 71.7 100 94.57 87.38 73.81 100 100 89.53 100 100 87.95 77.14 86.59 90 100 100 73.81 72.41 85.71 85 77.08 100 100 86.15 95.08 100 87.01 83.53 91.3 89.42 100 100 91.03 89.25 100 76.06 88.78 100 100 87.6 94.17 92 86.84 100 88.04 100 100 87.5 86.27 100 76.19 100 100 92.92 100 100 79.8 100 100 100 80.34 100 81.82 100 100 90.43 91.6 83.72 85 100 100 100 100 100 64.94 100 88.89 83.33 100 85.71 100 100 81.48 100 100 93.81 88.89 89.47 93.64 89.19 100 84.48 89.08 92.54 87.7 100 100 100 100 100 80.43 91.8 86.67 100 100 100 100 100 100 100 85.58 78.95 91.3 NA 100 NA 100 100 78.57 82.61 100 85.56 84.13 91.82 79.05 100 100 87.91 87.83 100 76.47 100 100 87.41 79.78 100 88.1 93.93 76.43 -17.5 0.002542 0.046671 K cassette NIPAL2 chr8 - chr8:99224730-99234706 chr8:99224730-99229266;chr8:99229515-99234706 chr8:99229267-99229514 NA NA 20.45 19.05 12.5 NA 15.38 10.45 8.33 22 11.76 NA 17.39 10.75 10.26 NA 16.67 21.84 11.43 5.56 20.41 32 6.67 13.04 4.17 NA 16.22 17.07 18.52 12.9 16.67 12.12 20 11.43 8.04 NA 14.29 18.18 21.88 27.78 11.11 21.82 13.64 13.16 22.22 10.26 9.52 15.38 16.67 13.51 10.2 32.14 25 12.5 11.54 14.29 11.11 20.75 14.29 17.65 13.89 50 23.88 29.73 17.86 29.03 18.31 12.2 16.67 25.58 23.08 NA 29.17 13.33 16.67 19.05 20 19.05 16.67 10.34 25 47.22 NA 12.96 36.36 13.85 8.7 13.64 18.92 13.16 14.29 NA 16 23.08 17.02 16.67 12.2 18.07 20.29 11.54 10.53 13.48 21.74 0 32 16.22 16.22 11.76 15.22 8.33 12.5 17.5 22.86 15.79 22.86 14.89 16.13 13.13 14.81 15.79 8.82 11.76 16.05 9.09 12.5 9.09 17.65 NA 13.79 NA 8.33 20.83 31.43 25 14.29 16.67 14.29 28.21 23.81 9.09 13.79 12.37 24 18.18 16.67 14.29 21.43 22.86 15.38 NA NA NA 13.58 35 25.93 32 13.58 21.21 23.08 33.33 19.61 NA 11.43 26.67 NA 14.29 18.92 24.24 20.83 19.15 23.08 7.14 16.17 29.96 13.79 0.002661 0.048122 K alternative_acceptor NOP16 chr5 - chr5:175811288-175812221;chr5:175811285-175812221 chr5:175811376-175812221 chr5:175811285-175811287;chr5:175811288-175811375 chr5:175811284-175811285;chr5:175811287-175811288 100 84.21 85.29 73.68 87.95 78.48 78.85 78.7 76.47 91.18 100 NA 62.5 80 86.11 76 85.71 76.56 77.14 82.61 69.23 66.67 71.43 73.68 71.31 83.78 97.06 81.19 78.33 95.45 83.33 83.78 97.67 84.48 100 68.89 78.57 73.48 77.27 72.84 96.77 94.44 71.64 90.36 73.24 69.23 72.37 80 79.8 92.98 84.46 61.2 72.31 85.23 86.36 81.61 96.88 82.86 71.83 79.1 75.32 72.55 69.23 96.97 82.42 74.65 76.39 74.07 82.09 65.85 77.14 86.67 82.35 74.63 97.14 71.21 100 79.45 75 77.89 80 77.42 63.64 82.98 82.93 65.71 97.06 76 77.22 68.85 96.77 70 100 100 68.66 91.67 81.08 60.99 74.65 84 71.02 65.45 71.54 76.09 78.26 89.47 68 75.76 77.78 67.74 76.92 84.13 82.5 95.24 82.35 78.79 73.13 80.99 96.97 81.48 74.42 88.14 74.19 69.57 80.95 86.3 82.46 100 71.74 95.83 78.81 65.79 81.43 82.86 78.38 100 81.13 79.31 78.38 100 80.72 75 70.93 71.88 78.75 70.69 78.85 72.73 64.29 96.77 81.25 79.31 73.2 78.5 72.73 100 78.08 96.3 83.64 56.41 63.27 71.83 79.12 69.39 86.76 63.01 69.23 81.67 73.91 81.08 78.79 88.68 78.83 67.37 -11.46 0.000547 0.02724 N alternative_acceptor NPIP chr16 + chr16:15044113-15044560;chr16:15044113-15045471;chr16:15044113-15044591 chr16:15044113-15044608 chr16:15044561-15044591;chr16:15044592-15044608;chr16:15044609-15045471 chr16:15044591-15044592;chr16:15044608-15044609;chr16:15045471-15045472 41.52 52.83 40.79 24.6 54.76 21.57 28.72 45.62 51.61 48.97 54.39 43.7 43.67 44.07 46.27 45.58 28.92 35.84 44.98 32.99 50.22 43.84 58.03 35.62 37.94 31.28 60.31 30.32 50.76 51.15 31.19 42.86 44.07 40.76 56.22 21.43 51.38 41.62 38.65 36.36 42.35 48.86 49.83 48.43 57.18 42.63 31.85 36.77 48.27 45.76 40.66 30.39 47.4 39.37 34.75 41.75 36.92 45.45 51.89 38.88 52.23 50.38 51.2 28.25 42.9 40.04 47.83 45.56 51.96 30.1 35.67 44.9 54.5 40.82 43.57 50.69 45.45 42.37 43 34.96 40.21 43.96 37.67 43.6 40.33 45.66 51.06 45.52 34.66 24.67 49.39 31.17 43.42 59.26 35.75 52.34 53.28 36.13 45.38 27.25 44.31 47.58 34.83 42.41 33.65 30.96 45.18 46.05 38.34 44.54 44.04 31.24 46.35 50.27 46.47 46.66 61.46 51.71 42.93 51.51 34.41 51.91 40.37 38.52 53.15 26.54 43.46 55.68 36.36 46.06 46.89 51.88 48.9 55.56 49.21 41.07 48.29 53 51.01 46.31 36.25 52.07 44.72 35.73 56.18 42.2 45.81 53.28 23.57 45.53 41.36 51.89 46.96 33.27 33.25 49.33 43.79 41.01 37.34 25.72 40.89 41.02 44.06 32.8 26.48 38.82 40.46 38.31 41.29 50.76 32.71 32.68 43.84 30.25 -13.6 0.000347 0.022265 N coord_cassette NQO2 chr6 + chr6:3000320-3006701 chr6:3000320-3002283;chr6:3002521-3003902;chr6:3004024-3006701 chr6:3002284-3002520;chr6:3003903-3004023 11.11 22.22 28.89 NA 5.77 6.25 21.43 15.38 29.41 100 15 NA 21.43 25.81 25 25 25 33.33 6.35 7.14 22.22 NA NA 14.29 NA 2.33 21.74 35.71 64.71 26.67 27.27 40 14.29 7.69 NA 0 26.67 20.41 12.31 16.67 25 30.43 20 26.67 11.32 40 21.43 20.51 22.73 35.71 5.8 0 8.33 NA 6.67 11.11 16.67 24.07 52.17 18.92 23.08 36.36 57.14 46.43 11.54 18.75 31.82 18.92 61.11 9.64 21.21 NA 58.82 32 40.74 27.27 22.22 6.67 31.91 28 13.64 46.03 11.76 8 43.48 NA 22.22 28.57 27.78 NA NA 16.67 30.77 NA 19.67 18.52 NA 68.42 34.62 10 42.11 27.03 13.04 22.73 26.92 44.44 44.44 42.31 50 NA 25.93 7.14 15.38 36.36 40 29.55 12.28 36.92 15.38 NA 25 15.38 28.57 42.11 37.5 12.77 33.33 27.78 20 NA 26.67 17.65 33.33 NA NA 6.06 22.22 NA 23.53 NA 26.32 26.67 18.18 11.63 10.81 28.81 27.78 50 NA NA NA 27.27 37.04 12 38.46 31.11 NA 7.14 33.33 6.67 9.62 30 39.13 8.57 15.38 NA 27.27 21.88 33.33 18.18 20 30.43 25 8.16 -16.84 0.001816 0.043154 N cassette NRXN2 chr11 - chr11:64390551-64397873;chr11:64387845-64397873 chr11:64387845-64393934,chr11:64390551-64393934;chr11:64394025-64397873 chr11:64393935-64394024 NA 45.1 34.15 39.66 37.5 29.2 NA 55.26 39.13 42.71 56.41 NA 39.39 NA 48.97 48.94 28.33 NA 31.82 NA NA NA NA 35.47 49.17 NA 39.13 NA 38.46 36.36 26.56 33.33 31.25 NA 43.59 60.78 58.82 29.69 36.59 55.44 39.39 40.62 28.12 20 NA 41.98 35.66 31.34 32.14 52.63 36.73 NA 21.43 43.22 44.94 29.79 48.65 44.86 34.16 40.28 38.16 NA NA 26.67 38.66 45.31 40 61.54 38.1 53.45 54.17 36.04 40.67 38.46 NA 54.05 52.38 35.34 23.08 23.26 NA 25.77 38.04 NA 20 40.38 33.92 35.89 45.21 NA 34.29 53.85 30.77 NA NA NA 50 19.3 28.57 31.27 33.58 36.67 50 37.97 31.33 44.26 37.5 40.54 NA 46.67 32.69 35 31.05 33.59 49.25 25 30.16 28.3 42.86 44.44 36.15 NA 37.93 35.16 48.28 28.46 48.48 NA 33.33 43.4 NA NA NA 35.48 NA NA 71.43 45.83 NA NA 39.76 NA 35.29 28.57 100 NA NA 54.55 36.59 NA NA NA 29.03 36.75 40 39.39 50.88 NA 50 59.02 NA NA 39.22 NA 33.59 NA NA 31.43 31.58 42.37 32.54 42.86 37.97 55.44 17.47 0.000683 0.017564 K cassette NSUN2 chr5 - chr5:6625783-6632711 chr5:6625783-6631985;chr5:6632091-6632711 chr5:6631986-6632090 100 100 100 100 88.73 100 100 100 100 100 100 NA 100 100 100 91.57 82 91.18 100 100 89.34 100 100 100 89.86 100 100 93.41 93.59 100 92.31 100 100 100 100 74.36 95.54 100 92.31 82.35 100 100 100 100 100 100 92.19 87.62 91.75 100 93.42 86.36 100 100 91.04 91.8 100 86.49 90.36 100 100 100 100 92.06 100 100 100 90.41 100 90.91 93.42 100 92.19 100 94.95 95.28 100 91.3 100 85.33 81.82 100 90.59 88.46 100 100 100 88.76 100 96.03 100 100 90.48 100 87.91 100 100 100 100 100 93.67 100 90.36 100 92.38 100 92.86 93.14 100 100 93.86 90.32 100 100 100 100 90.11 100 100 87.5 92.86 100 100 86.54 81.25 90.79 100 100 88.89 100 100 100 100 100 100 89.19 100 100 100 100 100 88.64 100 94.78 100 93.14 100 100 100 100 NA 100 100 91.3 100 92.41 100 88.37 89.53 80 91.51 100 91.57 89.04 88.73 87.5 91.59 100 90 92.08 100 100 100 84.35 -15.65 0.001269 0.028068 N mutually_exclusive NT5C2 chr10 - chr10:104866464-104899162,chr10:104899237-104934614 chr10:104866464-104871501,chr10:104871563-104934614 chr10:104899163-104899236 chr10:104871502-104871562 0 0 0 0 0 5.88 5.26 0 0 1.61 0 30.43 0 0 0 9.2 5.75 0 5.43 0 0 0 0 0 7.23 4.76 0 0 8.14 4.71 0 0 0 0 0 2.13 0 0 6.6 12.5 13.21 0 7.53 0 0 4.04 7.84 3.33 0 4 5.04 18.87 0 5.5 0 0 0 0 0 0 4.92 6.93 0 0 3.6 0 0 0 6.42 12.64 8.25 6.31 4.08 5.32 0 7.06 0 2.04 8.82 7.26 8.97 14.75 0 0 5.13 0 1.45 0 7.46 8.45 0 12.5 0 0 5.22 1.35 0 0 0 0 4.44 0 0 0 13.58 7.41 7.58 0 7.22 0 0 7.87 20.19 1.14 2.27 0.66 0 8 8.45 0 9 3.17 8.75 10.76 0 0 0 0 0.83 0 0 0 0 0 0 1.41 0 0 0 5 2 0 0 0 0 4.35 0 0 10 0 0 0 7.76 10 8.82 0 0 7.78 5.94 9.33 0 19.74 4.35 8.6 0 0 0 10.91 0 0 0 0 0 12.5 12.5 0.00018 0.01128 N alternative_acceptor NUSAP1 chr15 + chr15:41641440-41643188;chr15:41641440-41643230;chr15:41641440-41642310 chr15:41641440-41643185 chr15:41642311-41643185;chr15:41643186-41643188;chr15:41643189-41643230 chr15:41643185-41643186;chr15:41643188-41643189;chr15:41643230-41643231 NA 54.35 49.15 35.71 56.34 38.46 23.53 45.56 43.61 71.43 56 NA 52.94 76 50.59 NA 54.39 45.24 50 38.24 62.16 53.12 39.77 41.77 75 44.9 46.86 53.1 65.79 46.15 50 44.44 46.67 54.9 62.42 31.08 60.71 47.62 50 31.25 35.71 50 42.11 59.32 50 58.33 60.71 50 54.84 62.5 57.95 32.08 37.78 40.28 70 47.22 30.88 47.73 53.73 58.57 58.06 50.82 39.29 48 50 48.08 48.57 42.55 45.95 36.36 44.78 52 60 39.05 59.26 46.81 47.37 45 52 49.33 37.14 52.38 64.29 45 40 56.9 50 41.67 51.28 51.38 58.62 34.97 57.35 42.11 38.89 70 50.55 38.3 47.87 47.22 56 47.06 51.55 56.6 41.18 46.15 49.01 48.1 46.55 57.89 82.35 40.3 57.14 56.25 53.78 60.71 48.44 31.33 47.83 57.58 47.5 47.31 45.45 46.32 43.02 54.87 46.88 60 48 53.52 55.56 58.14 48.39 59.09 50.79 50 46.83 48.84 62.12 64.71 39.29 56.04 89.13 47.06 43.94 36.84 40.54 56.76 46.67 54.88 84 NA 39.84 56.42 42.31 48.96 47.37 46.67 53.93 21.14 54.1 34.78 46.75 45.24 41.54 46.88 47.92 63.64 52.67 45.1 33.9 50 49.01 31.66 -17.34 0.000069 0.006 K cassette NVL chr1 - chr1:224505633-224517772 chr1:224505633-224514092;chr1:224514167-224517772 chr1:224514093-224514166 NA 100 69.23 NA 100 NA NA NA NA 100 100 NA 100 100 100 100 100 100 100 NA 100 100 100 100 NA NA 100 100 100 100 100 100 NA NA 100 100 100 100 100 72.22 NA 100 100 100 NA NA NA NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 NA 75 100 100 72 100 100 100 100 NA 100 100 100 NA 100 100 100 100 NA 100 100 NA 100 100 100 100 76.19 100 NA 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 NA NA 100 100 100 100 100 100 100 89.58 NA 78.95 100 100 100 100 100 100 NA 100 72.73 NA 100 100 100 100 NA 100 100 100 100 NA 100 100 NA 100 100 100 NA 100 NA NA 100 NA 100 100 NA 100 100 NA 100 100 100 100 100 100 100 NA 100 100 100 NA NA 100 100 88.09 -11.91 0.000007 0.000485 K alternative_acceptor OGT chrX + chrX:70753187-70756057 chrX:70753187-70756027 chrX:70756028-70756057 chrX:70756057-70756058 100 89.41 89.88 91.62 90.43 100 100 90.7 92.48 92.89 92.11 100 93.58 89.3 84.48 88.1 86.11 93.08 88.46 100 91.77 100 100 92 82.41 100 82.89 92.78 94.12 80.59 100 89.42 92.38 92.53 85.33 70.77 91.42 94.14 92.22 72.41 86.86 90.79 92.9 84.92 91.74 91.26 87.14 86.24 91.93 91.78 93.84 62.73 93.28 89.44 87.33 88.89 100 94.68 92.65 89.62 89.02 90.43 89.15 87.3 92.54 89.68 90.54 87.72 91.71 73.36 93.92 95.59 93.15 91.92 87.09 94.3 88.94 89.58 91.24 89.49 88.66 89.67 91.38 86.55 91.76 100 100 90 92.7 89.94 89.58 68.18 91.52 90.83 92.09 87.74 86.72 94.43 92.07 89.17 80.33 89.77 100 83.86 94.95 90.17 91.22 88.06 88.6 77.78 87.46 92.11 90.91 100 95.24 91.86 84.21 91.75 100 93.57 86.71 90.46 93.72 90.7 89.47 90.61 94.16 91.62 91.71 80.15 84.85 100 100 93.94 77.61 100 86.75 90.53 90.68 100 94.37 89.51 100 89.64 92.59 90.22 88.48 91.72 84.38 100 100 100 90.93 91.88 91.12 92.24 87.02 87.46 90.94 69.01 84.76 92.69 89.13 87.66 91 100 92.42 87.89 90.32 89.61 87.07 93.17 91.12 69.89 -21.23 0.000033 0.00317 K cassette OPA1 chr3 + chr3:193335075-193336657 chr3:193335075-193335572;chr3:193335627-193336657 chr3:193335573-193335626 NA 12 27.87 21.05 25.53 NA NA 23.19 25 25 15.79 0 25 20.51 26.53 17.5 21.95 15.52 17.65 NA 20 12.5 26.79 20 14.29 5.88 0 18.92 23.33 27.27 25 23.91 0 9.09 24.44 52.63 16.67 22.22 13.51 33.33 23.81 19.51 20 11.11 0 8 0 20 19.35 15.79 22.64 34.48 NA 19.7 17.07 20.83 7.14 37.93 14.89 23.26 16.98 24.14 27.91 24.39 16.13 23.53 0 18.75 16.67 30.61 17.02 20.69 14.29 15.79 16.67 22.22 20.69 26.09 21.43 20.83 19.05 17.65 33.33 6.67 20.93 0 10.42 31.58 17.74 26.67 7.41 51.52 3.45 29.41 19.05 0 48.15 18.52 22.86 NA 34.69 22.22 41.18 0 26.67 23.91 12.73 15.22 30.77 28 16.67 12.82 20.75 NA 33.33 25 10.81 10.91 0 22.08 22.58 21.43 20 29.41 18.87 0 20 21.88 22.41 6.67 24.07 35.42 36 0 NA 30 26.92 0 16.33 28.57 0 0 3.45 21.21 20.93 20.59 0 3.85 NA 0 0 0 14.29 17.39 16.67 21.88 15.79 31.58 22.73 38 8.89 NA 27.03 24.14 11.54 15.79 20.45 16.67 18.75 20.45 7.14 20.69 19.61 36.24 16.63 0.000092 0.004579 K cassette OPA1 chr3 + chr3:193336726-193349400 chr3:193336726-193343880;chr3:193343992-193349400 chr3:193343881-193343991 NA 28.57 40.74 26.67 37.14 NA NA 34.55 56.82 37.5 77.14 100 68.42 41.18 53.66 40 76.67 52.38 50 77.27 63.27 5.26 51.11 35.42 62.5 23.81 48 70.97 56.1 59.46 50 46.94 NA 59.09 46.67 81.48 53.33 47.06 61.76 76 52.38 32.35 45.71 48.57 100 57.58 58.33 52.63 50 72.73 50 100 NA 40.35 37.5 26.67 25 32.43 36.36 55 37.04 51.72 59.46 34.78 51.35 46.67 45.16 53.66 45 60 61.76 61.11 68.89 37.78 58.54 42.86 65.79 57.14 52.63 53.12 42.86 36.67 44.44 58.06 68.57 32.14 NA 55.88 54.72 51.28 NA 100 45 53.57 51.02 50 18.92 25 60.61 69.57 50 52.94 48.28 39.39 45.45 77.5 46.94 44.26 80 42.11 36 54.84 22.81 NA 61.29 51.28 42.22 55.36 100 55 68.52 49.09 24.56 41.18 55 62.96 64 69.57 49.18 25.81 43.33 46.15 59.26 NA 37.5 100 44.83 NA 55 100 NA 40.91 NA 47.92 48.15 51.06 NA 39.39 NA 23.81 NA 56 60.98 50 50 60 61.11 50 50 79.17 44.44 NA 53.45 40.62 38.71 60.87 61.7 59.26 47.54 43.18 50 36 50 80.33 30.33 0.000279 0.010388 N alternative_acceptor OSBPL1A chr18 - chr18:21946931-21948250 chr18:21946947-21948250 chr18:21946931-21946946 chr18:21946930-21946931 13.33 8.11 0 10 NA 0 0 NA 0 8.16 5.17 NA 0 0 7.41 0 0 0 6.25 NA 0 NA 0 0 0 0 8.82 0 18.18 0 5.41 NA 0 0 0 0 5.26 0 NA 43.75 NA NA 0 0 0 0 0 0 15.38 0 0 12.82 NA 0 13.64 0 0 0 NA 0 0 3.28 0 0 3.39 NA 0 0 0 20 0 0 6.25 0 0 0 0 NA 7.41 0 6.25 0 0 NA 3.03 NA 0 0 0 0 NA 28.57 0 0 0 0 16.67 2.86 10 5.36 0 0 0 0 0 6.9 0 0 0 12 0 0 8 21.05 0 0 NA 9.09 0 4.08 NA NA 7.69 0 0 0 0 NA 7.55 14.29 0 NA 0 NA NA 0 10.71 0 0 NA 10.53 8 0 0 NA 0 0 8.33 0 0 NA NA 3.64 4.44 0 7.69 13.33 0 0 10.81 7.14 0 9.09 10.53 0 11.11 7.69 0 NA 0 0 0 0 16.41 16.41 0.00032 0.021059 N alternative_acceptor P4HA1 chr10 - chr10:74770796-74773981 chr10:74773310-74773981 chr10:74770796-74773309 chr10:74770795-74770796 16.67 15.38 7.14 31.58 17.14 6.25 13.83 19.05 8.57 8.89 15.79 100 17.86 13.33 10.87 14.63 22.58 13.16 5 20 9.52 15.15 16.39 7.81 3.85 12.5 20.37 7.48 6.96 8.6 9.43 14.61 7.55 15.79 14.49 28.57 10.38 13.04 10.91 29.73 17.24 20.83 9.09 7.77 16.39 11.71 2.38 14 6.56 9.72 4.5 32.61 10.34 13.79 12.82 10.77 21.88 5.45 16.98 7.02 24.24 26.92 13.25 13.24 9.84 15.19 12.33 22.45 11.76 17.07 11.58 16.39 6.52 18.37 9.26 9.52 19.05 15.15 17.07 6.56 11.63 10.75 16.67 12.82 13.19 11.49 7.55 11.11 14.29 6.15 100 36.36 16.13 10.17 10.17 23.53 37.84 10.84 10.34 19.35 3.03 13.98 4.76 23.33 10.45 14.63 8.77 9.03 7.14 25 5.45 8.11 14.63 NA 6.76 11.76 7.87 7.25 10.61 8.33 14.89 16.39 12.24 12.77 11.29 7.89 14.29 34.48 6.38 25 6.9 22.81 13.33 37.5 26.32 9.62 11.76 17.39 19.44 25.49 28.21 22.73 17.39 6.38 20.83 11.36 14.29 18 35.71 8.22 24.24 14.86 14.49 17.24 10 9.29 16.9 15.15 12.2 17.54 16.67 15.15 6.38 10.34 10 4.69 10.66 14.04 10.71 6.9 12.5 7.14 12.77 29.15 16.38 0.000822 0.036512 N cassette PABPC4 chr1 - chr1:40029414-40030094;chr1:40029414-40030142 chr1:40029414-40029507;chr1:40029595-40030094,chr1:40029595-40030142 chr1:40029508-40029594 93.51 88.78 85.14 75.64 85.84 65.58 50.7 60.91 80.85 85.04 92.37 100 77.97 69.74 81.5 91.01 84.25 82.61 91.1 84.69 75.56 76.56 80.26 87.23 86.8 87.18 85.71 82.91 87.31 88 80.85 85.98 78.38 80.77 86.25 56.63 86.22 79.34 78.24 61.76 86.44 61.11 86.67 95.1 81.45 81.08 87.43 85.84 82.14 85.98 83.92 63.64 87.76 91.53 81.97 79.41 100 82.31 84.46 90.74 84.15 82.18 76.92 86.42 89.61 77.78 81.08 91.28 81.82 72.03 72.73 84.69 81.32 78.63 79.75 87.38 81.82 77.82 88.61 79.8 81.82 80.15 82.05 76.92 92.42 86.11 79.51 78.92 83.08 76.44 92.19 58.82 71.95 88.24 82.27 88.73 100 86.96 88.24 85.59 89.27 80.61 78.45 82.52 82.07 91.3 86.94 95.3 73.14 75.41 74.17 75.49 73.26 100 67.54 87.01 91.62 90.24 86.57 85.61 82.68 77.4 73.21 80 81.56 72.14 84.28 83.33 83.89 100 86.57 88.68 72.31 100 91.35 90.86 86.6 73.53 75.16 88 92.45 79.45 92.48 86.83 89.9 88.78 70 91.03 100 82.24 100 81.36 78.76 76.35 73.23 86.54 83.33 80 78.57 64.52 81.15 80.53 92.31 80.13 67.2 74.82 85.15 86.52 81.58 86.84 73.56 82.58 82.68 62.7 -19.98 0.00007 0.003778 K alternative_last_exon PACRGL chr4 + chr4:20715163-20728907 chr4:20715163-20726430 chr4:20728908-20729979 chr4:20726431-20726511 NA 10 21.74 8.33 39.13 NA 76.92 32.14 NA 2.63 70 NA 13.33 36.36 4 0 33.33 16.67 7.14 NA NA 7.69 0 52.94 NA NA 10 60 35.71 NA 7.14 10 NA 8.33 NA 90 9.52 27.59 53.33 58.82 64.71 4.55 46.15 41.67 18.18 4 50 84.62 27.78 23.08 22.22 92.86 33.33 45.83 36.36 33.33 NA NA 36.84 50 44.44 81.82 57.14 46.67 39.13 73.33 25 30 7.69 67.86 45 10 29.17 29.63 52.94 35.29 10 56.25 40 50 50 60 7.69 NA 23.53 4.76 10 50 43.48 43.33 NA 81.82 14.29 30 5 NA 5 9.09 16.22 NA 23.26 38.89 38.46 NA 30 42.11 39.29 38.24 43.48 6.25 25 30 33.33 NA 20.83 33.33 0 23.81 15.38 7.14 33.33 21.74 15 40 8.33 60 NA 50 86.67 18.75 29.03 94.44 56.25 6.25 7.14 18.75 84.62 NA 60.53 61.54 15.79 20 54.17 36.36 50 45.45 43.75 38.89 8.33 NA NA NA 46.15 10 36.84 10 33.33 42.86 24 95.24 29.41 16.67 5.26 31.58 7.69 50 7.69 36 14.29 6.25 29.41 40 30 85.91 55.91 0.000118 0.021773 N cassette PANK3 chr5 - chr5:167988522-167993017 chr5:167988522-167990893;chr5:167991071-167993017 chr5:167990894-167991070 NA 100 100 83.02 100 NA NA 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 74.07 100 100 100 100 100 100 100 78.57 100 100 100 86.11 100 90.91 100 100 100 100 100 100 100 100 100 84.62 NA 100 100 100 100 100 100 100 100 100 100 100 89.36 100 100 100 100 100 100 100 100 100 81.13 100 100 100 100 80.77 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 82.5 100 100 88.64 100 100 100 100 100 100 89.29 80.49 100 100 88.89 100 100 92.42 100 100 90.8 100 100 100 100 91.53 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 79.17 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 87.27 100 100 100 100 69.05 100 100 100 100 100 100 100 100 86.69 -13.31 0.000031 0.001883 N alternative_acceptor PARP4 chr13 - chr13:25005615-25008532 chr13:25006835-25008532 chr13:25005615-25006834 chr13:25005614-25005615 21.05 10.45 13.55 28.4 24.6 14.63 25 29.08 22.6 25.42 19.58 24.48 27.59 28.44 16.45 23.97 23.57 22.45 19.48 1.67 17.78 20.97 18.5 25 11.95 9.6 23.08 13 18.49 15.73 19.49 33.93 22.09 33.33 17.71 30.99 33.33 18.07 23.13 28.8 49.58 20.63 18.92 25.35 38.1 15.65 9.55 19.05 16 17.11 14.6 30 15.24 23.78 12.1 19.53 21.92 11.76 20.42 21.48 24.3 31.93 25 25 17.88 23.77 21.88 20.27 26.81 32.64 23.2 14.62 16.02 32.31 18.33 22.09 26.19 17.36 27.41 22.84 26.62 25.45 25 16.67 25 13.93 25.71 16.95 34.11 10.08 36.51 37.5 33.68 19.35 18.58 27.59 31.34 19.63 22.27 31.43 17.96 23.83 15.79 23.33 28.48 15.83 16.91 24.1 16.85 20.41 20.16 16.67 20.18 33.87 13.89 24.83 16.13 27.88 20.83 17.32 22.73 18.97 18.78 22.58 20.93 18.18 27.84 34.62 12.77 31.13 16.83 32.06 18.3 25.75 32.32 15.27 26.06 25.2 31.36 20.83 27.41 21.14 14.79 17.69 20.98 16.75 32.14 31.19 33.33 18.05 11.76 12.9 14.63 21.05 26 30.11 26.67 27.59 16.81 36.28 19.61 18.05 24.58 22.22 22.22 18.52 23.58 25.52 18.3 27.55 25 15.14 21.48 31.81 10.33 0.000504 0.026586 K cassette PBX3 chr9 + chr9:128723129-128725290 chr9:128723129-128724380;chr9:128724494-128725290 chr9:128724381-128724493 NA 55.26 NA 35.9 58.33 25.37 22.42 52.82 NA NA 46.67 100 35.42 61.4 NA NA 64.52 57.89 58.33 62.86 56.2 70.37 47.06 47.06 50.81 NA 65 38.89 57.46 47.17 NA 49.59 NA NA 54.09 74.07 57.94 60.87 35.29 58.33 38.24 NA 45.22 47.03 16.67 53.66 45.78 46.43 51.85 45.66 NA 57.43 NA NA 47.62 48.94 NA 46.88 55.56 55.17 49.54 NA 37.62 61.54 47.62 51.88 54.5 45.16 58.33 100 46.93 37.5 NA 47.73 60.87 47.06 41.03 38.46 48.24 55.81 NA 41.67 62.07 40.74 52.78 53.12 40 NA 42.11 54.76 60 72.22 66 NA 54.55 NA 52.63 56.58 52.9 57.14 45.07 48.17 48.13 55 41.54 43.59 56.94 51.96 44.17 100 41.38 56 40.54 40 55.88 43.75 43.48 43.48 16.67 48.15 NA 33.33 53.12 43.48 NA 18.75 36.36 50 47.34 32.14 56.92 50 53.15 NA 52.44 57.04 64.44 43.48 67.03 55.17 47.37 57.58 NA 40.91 46.15 54.95 NA NA 55.1 51.52 50 32.14 51.32 50.94 NA 71.43 51.35 33.33 51.02 65.38 46.43 NA 34.62 NA 34.85 60.49 46.53 52.38 31.25 37.93 42.99 NA 49.8 68.8 19 0.000341 0.01195 N cassette PCM1 chr8 + chr8:17830197-17842955;chr8:17830197-17840741 chr8:17830197-17838099;chr8:17838265-17842955,chr8:17838265-17840741 chr8:17838100-17838264 68.33 69.91 70.21 70.68 65.03 65.52 32.5 66.2 65.85 74.24 78.4 100 65.33 71.82 81.37 72.73 65.32 79.71 68.67 58.9 55.7 68.97 63.95 60.17 60.98 72 74 70.33 72.34 61.73 68.86 73.98 77.22 73.91 66.48 85.19 62.5 67.94 69.23 81.48 45.21 74.44 60.32 72.51 82.22 68.29 53.73 62.42 70.15 56.25 56.8 74.74 58.54 70.4 75.86 61.54 51.14 69.49 70.59 64.95 65.26 57.14 66.22 65.57 65.56 63.38 74.55 68.29 75.96 85.57 64.29 68.04 70.25 62.5 60.49 67.77 57.73 48.21 58.65 80 61.04 62.62 65.22 51.09 71.9 80.33 69.88 65.62 76.64 81.25 61.7 81.55 72.33 65.92 65.77 59.49 76.55 42.57 76.15 72.22 80.69 65.81 54.67 68.42 80.2 70.59 67.97 75 74.51 70.97 84.62 79.34 70 100 53.7 70.94 69.34 55.61 77.42 68.6 71.72 70.15 65.43 73.53 81.88 76.39 62.9 67.74 76 54.73 71.13 70.95 85.05 72.58 56.07 68.33 77.48 62.92 71.91 61.29 75 74.73 79.76 67.02 63.7 70 73.77 72.31 100 58.49 100 56.86 59.18 84.78 58.06 72.73 75.22 56.25 64.21 84.54 51.39 78.4 69.57 63.5 56.67 66.67 71.85 59.36 73.72 64.71 55.06 60.45 68.6 83.05 14.45 0.00028 0.01039 K cassette PCM1 chr8 + chr8:17797371-17804694 chr8:17797371-17797550;chr8:17797668-17804694 chr8:17797551-17797667 11.11 30 19.72 19.2 19.78 NA NA 26.6 45.83 30.21 21.54 NA 30.77 21.54 41.67 42.2 49.59 25 30.43 35.71 38.46 17.5 44.93 31.71 48.15 10.26 22.54 47.06 25 40.35 21.77 27 30.77 18.18 26.98 58.7 24.62 33.7 38.81 45.33 36.84 25 33.96 25.68 29.63 24.19 20 30.53 31.58 27.08 31.82 42.37 28.12 31.28 37.84 43.33 41.54 21.95 36.36 28.57 34.83 23.71 38.18 26.32 35.58 44.83 41.79 42.31 29.27 30 42.59 52.38 31.34 27.63 32.81 41.79 41.38 38.36 35.29 27.85 26.67 34.92 38.71 48.48 32.74 26.56 50 39.62 35.78 47.17 50.94 57.69 30.51 38.98 34.25 28.05 32 32.54 33.33 36.92 34.33 30 24.24 30.56 38.46 32.35 32.29 30.26 25 33.87 31.15 28.57 14.68 44.12 28.23 22.99 17.86 44.25 34.62 27.72 32.1 30 29.63 28.57 33.33 40 43.18 39.18 43.28 30.33 35.34 35.46 42.86 25.77 30.38 28.3 38.89 44.62 31.21 29.41 35.42 27.5 29.41 24.69 44.26 27.69 30.77 40.22 NA 21.74 NA 23.26 42.11 45.45 33.75 28.57 40 31.11 25.74 53.49 35.62 25.35 23.71 28.42 17.24 23.08 34.58 27.78 32.11 35.16 42.11 24.07 31.25 49.41 18.16 0.00215 0.041386 K cassette PDGFC chr4 - chr4:157771569-157891937 chr4:157771569-157782580;chr4:157782642-157891937 chr4:157782581-157782641 0 24.53 18.68 22.22 22.22 NA NA 9.09 NA NA 23.33 NA 0 0 0 14.81 NA 17.39 NA NA 33.33 NA 28 45.45 NA NA 28.57 NA 21.43 54.17 28.57 31.91 NA NA NA 40.91 28.57 NA 22.73 40.91 NA 0 30 21.05 16.67 NA NA 28.12 28.57 19.05 NA NA NA 23.08 22.22 11.11 NA 23.08 16.67 22 0 NA 35 42.31 35.71 NA 30 15 17.24 32.31 22.73 20.75 14.71 24.32 15.79 22.22 24.39 NA 18.18 27.78 NA 0 18 17.65 25 NA 0 21.74 22.03 17.65 27.19 64.29 18.92 25.58 26.37 33.33 26.67 8.57 29.63 18.18 23.08 20 NA 15.38 20 21.43 0 20 37.5 43.33 41.18 26.32 24.05 23.4 18.33 25.61 11.11 36 NA 31.43 16.44 38.1 22.22 20 18.37 5.26 31.43 9.09 NA 28 7.69 0 14.81 0 NA NA 16.67 NA 8.33 NA 20 7.14 NA 0 16.67 16.67 NA 5.56 13.33 NA 0 20 17.65 NA 13.04 NA 19.35 NA 12.9 33.33 18.18 18.18 NA NA NA NA 25 11.76 22.58 NA 46.67 15.15 20 40.91 20.91 0.000982 0.022905 K alternative_acceptor PICALM chr11 - chr11:85693032-85694908 chr11:85693047-85694908 chr11:85693032-85693046 chr11:85693031-85693032 50.94 47.43 54.26 40.98 48.75 51.43 35.29 52.38 45.39 42.45 48.79 43.53 44.79 44.26 45.19 48.4 37.19 45.6 50 48.85 44.57 51.76 41.53 51.05 43.4 48.3 44.71 47.15 50.87 44.37 48.1 48.89 62.75 48.54 45.92 77.65 53.61 42.18 46.58 75.27 35.21 44.74 43.88 43.8 46.71 45 51.22 48.82 50.51 38.74 47.19 74.07 44.83 45.7 41.96 36.77 49.57 52 51.06 43.35 40.86 51.28 47.11 49.25 49.21 52.34 46.73 48.7 46.79 67.09 50.92 61.19 46.56 48.96 43.44 41.67 43.83 52.52 54.67 41.49 66.04 49.11 48.09 49.22 44.95 44.03 51.33 49.14 47.95 57.89 50.82 73.68 51.72 43.48 41.18 43.24 52.34 46.67 48.03 55.43 37.93 43.22 46.4 45.16 54.74 50.31 42.62 43.79 43.98 50.61 40.34 46.55 47.65 52.24 53.9 53.38 44.71 50 55.06 47.44 48.8 50.68 46.15 48.74 51.15 46.33 54.14 45.69 43.7 47.58 40.91 44.92 46.24 40.59 40.64 48.15 47.8 43.62 43.53 39.15 38.55 59.77 52.73 46 56.59 45.82 56.14 49.23 49.35 51.98 43.4 49.81 46.99 35.11 53.09 39.42 42.86 48.28 46.92 77.71 54.21 54.12 42.28 48.12 45 53.66 54.17 55.71 41.88 46.81 50.65 49.48 47.44 74.67 27.23 0.000033 0.003225 N cassette PIK3C2A chr11 - chr11:17121517-17124208 chr11:17121517-17122824;chr11:17122982-17124208 chr11:17122825-17122981 NA 100 100 100 100 NA 50 79.41 100 100 100 100 100 100 100 71.88 82.5 100 100 100 100 NA 100 100 100 NA 100 100 100 100 87.27 100 100 100 100 72.22 100 100 100 100 64.52 100 100 100 100 100 NA 84.31 100 100 100 64.29 100 80 100 100 100 100 100 100 100 100 100 100 100 65.22 100 76.19 100 100 100 100 100 100 100 100 100 100 100 100 55.56 100 100 100 100 100 NA 100 100 100 100 59.38 100 100 100 100 100 100 100 100 100 100 NA 100 86.67 100 100 100 100 100 100 100 78.38 NA 81.82 100 100 90.38 NA 100 100 100 100 80.65 100 100 100 100 100 100 100 NA 100 100 100 NA 100 100 100 100 100 100 NA 100 100 100 100 100 NA 100 NA 100 100 100 100 100 100 65.62 86.49 69.57 80.65 100 100 100 61.11 100 100 100 100 100 84.85 69.57 100 70.89 -29.11 0.000209 0.008467 N cassette PIKFYVE chr2 + chr2:209210872-209214747 chr2:209210872-209212582;chr2:209212748-209214747 chr2:209212583-209212747 100 93.24 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.17 89.04 89.08 100 100 100 100 100 100 100 100 100 100 100 88.76 100 100 100 100 100 100 100 100 88.61 100 100 100 100 100 100 100 100 85.32 100 80.82 88.24 100 100 100 89.13 100 100 100 95.5 100 100 91.67 100 94.17 100 100 100 100 100 100 100 83.8 100 88.76 100 100 100 100 100 92 100 100 100 100 100 100 100 100 100 100 89.66 91.3 100 100 100 100 92.38 100 100 86.46 100 100 100 100 100 93.57 100 100 100 100 100 92.97 100 100 100 100 88.32 100 100 100 93.4 93.75 100 100 100 91.94 100 100 100 100 100 100 100 100 100 100 81.16 100 100 100 100 100 92.47 100 100 100 100 100 100 NA 100 100 100 100 91.53 100 82.29 100 87.78 100 100 100 92.19 89.36 87.04 100 100 100 95.65 100 100 100 89.13 -10.87 0.001869 0.037741 N cassette PIKFYVE chr2 + chr2:209215672-209217377 chr2:209215672-209216075;chr2:209216180-209217377 chr2:209216076-209216179 100 100 100 100 100 NA 100 74.58 100 100 100 100 100 100 100 100 86.27 100 100 46.67 100 100 100 100 100 100 100 86.96 100 100 100 90.57 100 100 100 81.82 100 100 100 100 82.98 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 84.13 100 100 100 100 100 100 100 78.46 100 100 100 100 88.46 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92.31 100 80.39 100 100 100 100 87.18 100 100 100 100 100 80 100 100 100 100 100 100 100 100 100 100 100 100 92.77 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 77.08 100 100 100 100 75.44 100 100 100 100 100 100 92.31 100 100 100 60.87 100 100 81.1 -18.9 0.000004 0.000306 K cassette PLD1 chr3 - chr3:171395485-171405160 chr3:171395485-171404474;chr3:171404589-171405160 chr3:171404475-171404588 100 100 83.33 NA 80 NA NA 70 100 100 100 NA NA 100 64.29 100 70.83 100 83.93 26.47 100 100 100 100 100 100 100 100 76.19 100 85.71 60 100 100 100 46.15 66.67 83.33 60.53 52.63 72 NA 100 100 NA 76.92 100 35.29 81.63 100 100 100 100 100 NA 100 77.78 100 56.41 100 100 100 70.83 73.58 78.57 NA 100 78.79 100 35.14 73.91 NA 100 76 100 76.67 73.68 NA NA 100 76.32 100 100 100 100 78.26 NA NA 84.31 100 NA 67.86 100 100 71.43 100 NA 57.58 79.55 73.33 100 100 100 100 NA NA 89.39 77.14 100 100 NA 100 100 NA 41.18 81.4 70.69 NA NA 100 NA 72.88 100 100 86 NA 78.26 85.11 100 100 100 68.85 100 NA 65 100 100 58.33 50.94 100 80.85 100 100 66.67 NA 100 100 100 NA NA NA NA NA 100 65.38 100 77.08 67.39 45.45 44 85.71 100 90 80.85 NA NA 78.57 61.7 73.08 NA 47.62 83.33 100 49.39 -50.61 0.002768 0.049402 N cassette PLEKHM2 chr1 + chr1:16046416-16051811 chr1:16046416-16047823;chr1:16047884-16051811 chr1:16047824-16047883 33.33 51.79 30.43 28 54.55 21.05 25.37 42.42 57.14 43.66 51.65 34.09 44.93 44.68 18.57 22.41 20.9 50 31.58 54.29 34.18 42.86 47.62 34.78 52.48 50 66.67 55.64 64 56.52 40.96 40.98 21.88 33.78 38.46 21.43 32.31 33.78 47.83 22.22 51.11 31.11 52.73 36.11 62.32 52.94 45.1 55.84 27.78 42.11 42.86 33.78 50 39.73 44.29 35.92 38 49.15 45.24 44.09 31.82 36.71 51.92 38.46 26.92 25.93 32.2 35.59 40.28 27.27 34.55 29.09 19.78 51.11 58.16 46.75 27.59 33.75 16.67 34.33 33.33 32.93 49.25 29.89 32.14 20.69 24.14 41.38 37.23 57.93 34.88 29.17 31.82 60 45.78 45.45 51.43 19.17 27.17 45.57 47.5 44.95 47.73 46.34 51.02 42.39 38.6 31.82 54.5 45.24 43.27 36.71 45.05 21.67 35.23 35 34.78 46.81 48.33 46.9 30.77 30.91 43.61 41.38 27.54 39.74 30.51 16.67 50.49 45.16 52.54 33.33 52.17 18.42 54.9 67.74 62.5 33.33 35.42 66.67 40.91 31.58 22.58 36.63 37.14 63.33 39.29 63.64 38.89 80 40.91 80 37.14 38.18 23.26 66.67 38 32.65 31.67 27.16 30.16 50 42.65 37.25 31.82 58.06 30.23 43.48 35.87 31.82 18.57 36.54 39.29 27.21 -12.07 0.002235 0.042702 N alternative_acceptor POLG2 chr17 - chr17:62479092-62481844 chr17:62479117-62481844 chr17:62479092-62479116 chr17:62479091-62479092 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.89 100 100 100 100 100 100 100 100 100 100 100 85.45 100 100 100 78.12 100 100 100 100 100 100 100 100 100 100 70.45 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 71.43 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 84.27 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.38 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 78.26 100 100 100 100 76.19 100 100 100 100 100 100 100 100 89.13 -10.87 0 0.000075 K cassette PPHLN1 chr12 + chr12:42729777-42748962 chr12:42729777-42745686;chr12:42745852-42748962 chr12:42745687-42745851 66.67 48.35 70.11 43.43 62.26 60.67 84.47 69.77 65.81 50 55.56 65.45 61.29 64.81 70.83 72.31 46.49 49.06 61.24 69.09 63.92 41.38 62.5 58.12 80 52.17 52.25 56.43 64.44 71.43 79.79 50 69.05 56.76 45 44.44 62.86 53.15 59.6 33.33 69.64 68.42 54.21 48.21 65.15 58.06 61.9 62.35 61.39 57.39 60.42 47 71.43 69.23 49 51.49 61.06 54.37 54.31 62.86 54.1 75 71.83 72.09 60.25 76.74 57.05 48.44 59.15 41.76 50.76 60 57.89 61.94 63.35 52.07 71.83 49.6 58.62 57.85 56.57 58.82 52.81 62.11 62.62 68.6 44.55 64.1 59.8 64.46 47 32.81 57.43 59.86 49.3 54.84 30.33 27.07 66.17 62.07 68.33 59.01 60.18 60.42 67.59 58.06 65.06 63.24 63.08 39.18 54.69 73.85 40.14 60.78 54.55 44.62 62.4 83.33 60.55 55.03 58.39 66.5 42.36 50 70.97 72.31 65.56 61.76 50 40.59 40.52 63.92 65.26 68.75 44.44 46.72 50.31 51.69 54.72 45 55.56 38.41 39.37 52.27 54.4 66.43 52.05 39.25 78.79 55.36 40.7 65 58.48 59.17 64.58 73.13 62.61 59.09 43.26 29.29 49.11 52.44 65.57 53.26 50 40.35 74.82 55.1 63.29 59.81 69.81 65.28 59.81 37.55 -22.27 0.000229 0.009112 K alternative_acceptor PPIE chr1 + chr1:40209597-40211085 chr1:40209597-40211046 chr1:40211047-40211085 chr1:40211085-40211086 100 100 78.57 100 100 100 71.43 100 86 74.36 88.1 NA 100 100 100 100 71.43 100 87.76 100 85 100 100 87.27 89.13 100 100 77.61 81.58 100 100 100 100 87.27 86.11 63.89 89.36 81.94 100 71.43 100 100 83.33 100 100 81.82 86.67 84.15 82.35 75 84.62 72.92 100 100 100 87.5 100 62.86 84.38 83.33 100 71.43 100 100 83.33 100 100 100 86.67 76.6 80.39 100 100 100 75 86.84 78.79 100 100 89.58 78.79 100 83.87 77.14 82.5 100 100 87.18 76.67 89.02 100 68.18 100 100 100 100 100 72.73 80 85.71 85.29 85.37 90 85.29 80.95 100 88.52 100 79.41 100 100 100 80 100 85.29 100 100 83.75 78.79 93.51 87.23 81.82 73.21 87.3 100 87.65 100 100 83.33 100 83.33 100 100 100 100 100 100 100 100 100 100 100 100 83.61 76.92 81.82 100 83.33 NA 100 100 100 100 77.78 71.05 100 100 73.33 90.38 81.82 76.47 100 83.64 85 71.43 80.43 100 86.49 100 100 100 76.92 100 72.18 -27.82 0.000076 0.006524 K cassette PPIP5K2 chr5 + chr5:102520446-102526542 chr5:102520446-102522020;chr5:102522141-102526542 chr5:102522021-102522140 16.33 33.33 23.78 26.6 23.21 2.27 25 16.39 36.76 29.14 20.49 1.15 37.04 27.78 20.83 29.49 38.39 16.43 43.59 20.99 27.37 15.79 19.35 32.37 20 31.82 25.35 31.03 31.52 28.09 20.27 27.08 27.78 34.18 30.63 38.18 25.98 26.47 22.31 37.23 23.21 23.47 22.78 19.59 21.25 27.96 32.2 33.33 31.97 33.55 30.51 38.6 47.73 14.29 33.33 35.06 22.45 34.25 26.47 31.31 32 41.1 28.99 19.05 43.38 12.12 38.24 25.86 26.83 32.43 28.7 33.33 29.03 24.81 23.58 27.97 41.67 44 25.62 35.09 52.63 35.05 36.25 44.34 36.36 10 13.93 39.8 39.41 21.84 32 44.16 31.15 27.88 23.02 25.71 18.57 30.37 23.14 39.29 27.33 32.08 28.26 28.57 26.07 48.08 27.44 38.41 22.11 19.74 29.76 24.19 20.27 55.26 29.05 38.92 27.12 38.61 24.64 31.18 46.45 29.77 31.45 27.45 38.67 30.91 37.88 32.28 27.62 21.67 22.9 27.71 17.57 36.78 25.93 18.52 37.08 38.71 35.16 100 24.24 31.58 8.33 42.98 36.36 25.88 37.74 25.25 29.63 11.29 1.89 13.16 22.09 22.22 32 36.9 27.83 46.51 32.43 54.17 42.86 32.56 20.86 27.35 21.51 34.38 24.06 37.5 30.82 33.73 14.77 23.08 27.97 38.39 10.42 0.001853 0.03754 K alternative_last_exon PPM1B chr2 + chr2:44445677-44471366;chr2:44445677-44457551 chr2:44445677-44459454 chr2:44471367-44471522;chr2:44457552-44458610 chr2:44459455-44461741 38.36 42.18 39.34 28.57 39.63 24.64 17.52 38.95 37.7 41.86 44.64 40.69 31.52 51.55 37.5 39.19 29.09 39.62 38.19 41.38 55.12 40.79 43.52 33.87 50.62 30.9 41.29 35.16 43.08 50 37.6 37.2 35.62 36.99 53.14 21.52 37.36 39.75 36.3 25 40.83 27.6 44.63 52.81 35.8 36.52 40.57 32.5 43.9 48.09 48.97 27.5 33.73 38.22 32.98 35.92 27.17 40 40.65 43.28 35.79 35 37.63 34.91 34.26 33.62 39.66 32.11 33.33 33.7 36.05 29.21 46.4 33.88 36.76 41.54 30.63 33.04 42.06 44.16 22.92 37.86 42.16 40.16 37.76 45.5 19.64 31.15 30.95 38.25 50.68 22.95 41.94 42.61 33.99 42.05 34.44 30.83 43.58 40.32 43.23 44.36 48.53 34.75 25.75 30.82 40.94 45.75 46.67 37.4 38.79 39.82 30.08 48.78 44.09 31.65 49.21 35.2 32.65 36.36 23.58 33.76 34.38 29.17 34.81 32.79 43.9 43.18 40.43 33.11 61.66 34.13 50.56 32.78 57.55 53.7 41.38 45.71 39.45 49.04 35.05 44.85 26.73 39.77 32.89 45 29.17 42.75 43.54 57.34 47.24 38.97 40.2 27.89 32.47 38.4 38.98 39.74 34.52 26.73 34.62 42.16 44.7 36.63 17.05 41.38 44.23 34.95 37.58 38.97 35.65 34.71 38.36 25.87 -12.49 0.000325 0.032352 K cassette PRKAA1 chr5 - chr5:40771966-40775511 chr5:40771966-40775029;chr5:40775075-40775511 chr5:40775030-40775074 0 0 13.27 3.23 8.16 NA 12.77 13.33 12.96 0 0 NA 0 8.7 0 20 0 0 10.59 NA 9.52 0 0 4.35 10.53 0 0 20 11.11 15 9.76 4.65 0 0 0 7.41 10.26 14.49 0 26.32 31.82 8.7 17.86 0 0 8.33 0 15.79 14.29 6.56 14.06 23.33 0 7.14 0 0 0 11.54 5.56 10.2 12.2 17.24 22.5 12.2 7.94 0 17.39 5.41 0 19.51 6.82 22.22 13.7 8.33 14.52 0 25.71 10.98 5 0 21.05 0 0 15 5.88 0 0 13.73 2.82 15.38 NA 37.5 0 0 6.17 29.63 14.04 12 0 12.5 10.29 13.11 0 0 9.43 9.33 5.41 9.86 5.26 0 0 9.43 8.06 NA 3.33 10 10.87 25 0 12.64 2.53 13.24 9.86 18.6 0 11.43 8.33 0 9.52 0 0 0 0 0 0 0 0 0 5.71 0 0 21.21 0 9.52 0 17.57 15.38 5.26 NA NA NA 9.68 0 0 15.38 17.39 17.24 24.39 10.42 32.61 15.38 0 20.9 5.41 6.06 0 14.63 12.5 8.77 10 0 5.88 6.98 24.82 17.84 0.000743 0.018736 K cassette PRPF3 chr1 + chr1:150298340-150300778 chr1:150298340-150300015;chr1:150300112-150300778 chr1:150300016-150300111 56.76 37.5 26.47 51.02 25 50 54.55 33.9 27.46 44.93 48.98 NA 29.17 41.38 23.44 31.17 39.13 56.36 32.47 13.33 44.83 48.89 63.04 50 28.81 28.17 29.63 33.33 34.57 32 30.67 40.91 31.11 47.25 26.53 19.64 29.9 36.79 27.14 14.68 39.66 29.63 31.52 15.25 46.15 22.78 31.75 15.08 49.21 48.44 15.69 23.61 33.9 27.12 33.82 40 32.43 29.33 37.1 41.89 40.85 68.75 34.78 28.57 42.31 44.26 37.36 39.39 43.28 21.9 45.71 22.77 64.56 38.1 35.56 38 42.11 23.53 36.51 34.09 38.75 41.56 32.53 42.42 33.33 52.38 40 27.14 44.71 36.79 43.18 25.86 49.15 36.59 30.11 40.91 34 29.29 57.33 28 43.59 37.5 33.33 45.95 50.62 20.43 36.46 32.05 38.1 38.89 42.16 18.68 65.96 100 13.4 23.81 23.16 27.78 46.77 29.41 24.44 41.57 41.44 50.96 38.27 22.81 40.43 31.58 33.33 37.25 14.47 32.35 24.44 35.29 37.93 31.15 37.7 78.26 36.54 41.86 41.51 24.56 2.04 27.47 30.56 29.41 46.15 40.62 47.62 14.58 22.22 5 43.06 50 39.66 47.3 41.1 40.79 70 26.67 30.65 48.57 37.68 31.03 51.52 36.17 33.33 43.48 28.57 33.33 39.68 45.1 36.79 22.75 -14.04 0.000729 0.01844 K cassette PRPSAP2 chr17 + chr17:18769266-18775895 chr17:18769266-18770594;chr17:18770648-18775895 chr17:18770595-18770647 NA 80.43 88.24 83.33 100 100 51.61 78.12 82.14 100 75 100 100 77.14 100 100 76.19 80.49 100 100 100 100 100 76.19 100 100 100 100 100 87.18 NA 100 100 100 100 70.37 100 100 100 66.67 100 100 100 100 100 80.77 86.84 80.85 78.12 83.33 78.57 71.88 75.76 100 83.33 78.12 100 100 100 82.35 100 100 82.76 100 100 77.14 83.33 100 100 84.09 73.68 100 82.5 86.27 84.31 100 61.76 100 72.5 78.38 100 100 77.5 77.78 86.05 69.7 100 67.65 89.58 100 100 66.67 100 100 87.04 100 100 83.33 100 100 87.32 84.38 90.2 87.5 78.57 88.52 91.18 89.8 81.4 NA 100 71.43 77.5 100 100 87.93 100 100 100 100 86.67 86.27 72.5 82.19 80 100 100 100 100 76.19 100 100 100 100 100 100 100 100 74 100 76 71.43 100 100 100 86.27 100 100 NA 100 NA 100 81.13 68.52 83.87 78.26 79.17 75 85.71 73.17 81.25 63.89 100 100 51.72 100 83.33 82.86 86.27 85.71 100 100 100 71.12 -28.88 0.000286 0.010513 N alternative_acceptor PRR3 chr6 + chr6:30525990-30529610 chr6:30525990-30529104 chr6:30529105-30529610 chr6:30529610-30529611 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 62.5 100 73.68 NA 100 100 100 100 80 100 100 100 100 100 72.22 100 100 100 100 NA 100 100 100 60.87 100 100 100 100 100 66.67 100 100 76.92 78.57 100 75 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 81.25 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 86.67 84.78 100 100 100 100 100 86.67 100 100 100 100 100 100 100 100 100 100 77.5 100 100 100 100 100 100 100 83.33 100 100 73.08 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 NA 100 84.38 NA 100 100 NA 100 68.18 100 100 80 NA 100 100 100 100 76.92 NA 100 68.75 100 75 -25 0.000001 0.000103 K cassette PTBP1 chr19 + chr19:805188-806407 chr19:805188-805491;chr19:805570-806407 chr19:805492-805569 59.42 53.33 66.42 56.41 58.87 35.92 26.23 69.41 69.63 63.69 66.26 64.81 60.47 59.48 72.18 73.82 66.06 62.18 70.33 50.2 55.11 64.55 57.92 74.11 64.68 57.65 57.59 48.31 57.56 56.34 65.05 64.12 62.84 57.96 66.38 34.63 61.57 60.24 59.13 37.82 54.09 64.37 51.8 68.39 56.12 56.38 59.19 55.53 63.2 68.8 51.44 40.51 59.58 67.77 54.55 47.14 59.18 68.75 59.51 56.66 61 54.39 56.1 59.64 60.13 63.44 57.61 67.5 62.94 46.74 55.85 72.53 60.12 59.94 57.59 61.42 60.74 62.9 66.32 57.44 56.41 67.42 38.43 56.55 65.02 66.13 67.48 58.94 60.77 53.17 64.22 43.48 73.88 75.31 50.34 59.79 69.44 55.45 61.13 52.84 72.11 58.33 61.39 53.16 52.52 53.92 61.56 61.12 53.47 69.31 66.82 52.71 45.68 72.24 48.8 63.2 58.9 68 65.48 65.45 51.04 61.63 57.38 61.58 57.14 53.53 56.23 70.51 59.55 48.78 67.26 66.85 69.18 62.68 62.57 63.92 65.1 62.31 69.01 41.98 57.05 65.69 57.14 53.55 64.29 63.55 61.54 66.47 63.37 57.5 62.2 69.14 60.43 42.79 52.52 55.83 57.36 61.17 60.43 36.06 66.1 59.42 56.47 58.73 47.04 59.67 66.44 64 54.44 55.52 56.7 53.38 60.13 39.16 -20.97 0.000067 0.003662 N alternative_acceptor PTPN2 chr18 - chr18:12785844-12794382 chr18:12793574-12794382 chr18:12785844-12793573 chr18:12785843-12785844 24.84 29.63 37.36 37.25 42.37 10.62 7.08 21.93 24.69 43.93 34.65 28.12 32.47 33.82 24.81 52 31 35.63 37.86 8.93 21.85 32.46 25.74 27.48 14.66 10.83 31.21 17.13 31.06 29.05 22.31 25 51.38 35.56 19.29 37.5 34.46 20.38 23.18 43.51 39.84 49.44 27.78 22.07 29.7 36.14 20.42 23.75 27.18 18.57 22.52 52.54 34.44 33.33 24.36 26.25 28.05 29.73 35.51 31.52 33.33 45.26 26.55 24.11 36.36 30.16 38.83 32.26 25 57.46 23.46 28.21 36.89 36.63 21.88 25.74 30.26 25 40 22.56 29.67 39.02 37.38 17.54 36.25 29.08 26.53 20.97 21.95 25.96 38.1 46.67 40.78 27.37 24.14 25.25 23.76 27.72 38.01 35.14 36.52 20.96 14.55 34.38 31.06 26.32 36 30.3 13.27 23.4 31.63 29.35 32.26 31.43 22.09 33.59 33.88 32.62 24.56 23.36 21.9 24.48 23.2 16.95 26.09 22.61 19.19 49.28 19.87 37.88 18.54 29.89 22.88 46.43 32.84 18.75 33.03 29.55 31.33 24.79 23.16 32.67 21.14 31.63 36.36 15.54 32.31 35.17 14.74 15.2 16.56 14.68 17.99 16.29 20.93 41.05 33.88 42.25 37.5 48.51 32.35 19.89 36.19 22.92 24.77 20.17 27.27 30.28 32.43 34.52 37.31 22.78 28.21 47.59 19.38 0.000117 0.009109 N cassette PTPRA chr20 + chr20:2903932-2944917;chr20:2854407-2944917 chr20:2903932-2928627,chr20:2854407-2928627;chr20:2928671-2944917 chr20:2928628-2928670 100 91.14 91.6 72.6 100 84.21 68.89 92.19 100 87.5 100 100 84.85 81.94 82.89 100 100 100 88.72 100 85.9 100 84.09 83.64 90.41 87.74 83.58 78.99 92.31 85.71 91.51 77.57 100 79.39 82.76 75.71 89.87 86.14 88.1 66.67 80 84.62 85.71 80.95 85 90.22 80.6 88.24 83.95 80.95 91.38 86.67 74 95 79.46 83.87 77.46 84.55 84.11 88.89 81.73 100 87.32 89.77 87.13 100 89.86 91.53 94.39 77.97 81.11 87.14 91.67 85.05 87.25 83.15 75.36 79.55 85.05 80.7 84.21 87.88 100 80.6 95.45 88.33 81 89.47 84.96 90.67 100 61.54 100 100 81.82 90 93.62 77.69 88.42 87.41 92.74 78.95 87.64 88.24 85.53 81.13 89.69 82.04 92.08 86.25 90.59 100 77.94 100 86.9 87.88 90.79 79.9 83.72 93.89 81.31 82.11 77.97 85.95 85.11 81.88 100 85 91.35 84.09 89.52 84.8 84.78 100 78.43 100 93.18 100 84.27 78.33 100 100 100 81.95 85.44 93.33 87.5 88.76 100 100 100 100 80.31 100 88.52 100 83.12 88.41 83.84 69.89 89 83.33 90.36 82.67 68.67 80 88.89 89.86 84.14 91.53 100 78.21 87.5 72.8 -14.7 0.000698 0.01785 N cassette R3HDM1 chr2 + chr2:136362587-136379063 chr2:136362587-136374237;chr2:136374328-136379063 chr2:136374238-136374327 NA 42.59 25.44 45.76 46.81 NA NA 35.9 32.61 18.52 37.04 NA 31.43 60.71 32.31 66.67 51.35 20.83 50 55.56 60.87 18 26.39 39.53 70.97 41.86 46.43 37.5 53.57 60.98 45.83 42.31 100 41.38 51.16 76.92 42.37 43.9 52.94 62.5 35.71 22.22 56.82 41.89 36.36 45.45 57.14 45.1 44.12 39.13 30.67 73.33 35 32.63 40 40.74 20.51 38.71 44 77.42 54.55 48 45.16 42.11 43.24 33.33 56.76 46.94 45.45 78.05 35.71 53.7 57.41 47.46 51.52 40 41.46 43.18 48.98 45.45 37.04 30.77 40.54 46.34 47.62 42.11 4.65 34.62 57.45 45.65 100 52.17 42.86 33.33 41.67 37.93 32.35 10.64 32.2 66.67 48.98 43.4 64.29 51.85 42.31 72 34.85 50.68 68.75 45.71 47.06 73.91 35.38 42.42 37.21 33.9 41.18 43.48 41.94 30.99 65.22 37.1 44.19 37.5 49.02 46.15 59.09 60 54.39 42.31 47.44 39.53 40.85 56.86 NA 30.77 40.35 27.78 53.49 63.64 22.5 48.98 39.13 53.85 25 48.65 36.36 43.4 NA 35.59 9.09 29.41 43.1 25.71 44.19 50 48.15 27.78 36.11 63.64 41.51 34.48 53.57 38.46 42.86 52.63 42.86 36.54 39.08 35 51.72 43.59 42.86 68.48 25.62 0.000322 0.011521 N coord_cassette R3HDM1 chr2 + chr2:136362587-136379063 chr2:136362587-136373721;chr2:136373764-136374237;chr2:136374328-136379063 chr2:136373722-136373763;chr2:136374238-136374327 NA 13.89 2.3 28.89 7.41 NA NA 1.96 6.06 2.94 5.56 NA 4 8.33 2.22 35.71 10 3.39 10.34 NA 25 0 1.85 10.34 35.71 3.85 0 10.26 7.14 5.88 3.7 4.26 NA 0 6.67 50 8.11 4.17 11.11 25 NA 7.35 9.52 2.27 17.65 25 NA 15.15 13.64 16 1.89 46.67 18.75 0 10.81 5.88 8.82 13.64 6.67 NA 9.09 38.1 22.73 4.35 10.64 15.79 27.27 7.14 5.26 47.06 5.26 13.79 8 13.89 5.88 4 14.29 10.71 16.67 3.23 10.53 5.26 8.33 4.35 4.35 2.94 2.38 5.56 16.67 19.35 NA 15.38 20 0 6.67 5.26 14.81 0 4.76 16.67 19.35 14.29 9.09 0 21.05 22.22 4.44 5.26 9.09 24 10 NA 10.64 5 3.57 0 3.23 3.7 5.26 3.92 4 9.3 20 20 18.75 12.5 18.18 16.67 18.75 6.25 14.58 3.7 6.67 4.35 NA 14.29 5.56 7.14 9.09 NA 3.12 7.41 17.65 14.29 1.64 20.83 6.67 6.25 NA 2.56 3.23 0 2.94 3.7 7.69 12.5 6.67 13.33 17.86 11.11 3.12 5 3.7 7.69 4.76 10 3.03 2.94 11.67 7.14 12.5 12 7.14 35.84 28.7 0.000713 0.019592 K alternative_acceptor RALGDS chr9 - chr9:135985073-135985682 chr9:135985109-135985682 chr9:135985073-135985108 chr9:135985072-135985073 59.26 55.77 39.13 43.86 50 30.43 19.43 38.36 51.28 36 55.26 22.99 43.68 37.21 47.17 37.97 56.99 40.85 47.15 33.33 43.88 100 54.05 37.62 56.41 50 27.27 31.25 45.57 51.52 43.36 30.56 53.66 42.86 56 49.23 36.25 40.98 41.43 60.47 42.86 42.37 45.71 44 64.29 32.1 40.35 39.42 36.11 35.71 40.22 49.06 44.07 42.03 44.14 39.74 41.03 39.39 41.98 42.24 41.29 28.24 40 43.64 44.95 47.06 49.17 39.53 47.56 58 46.67 42.86 39.47 41.29 39.53 35.29 38.01 50.62 33.54 36.67 35.37 46.27 45.9 35.29 50.59 52.83 100 38.57 38.13 44.35 50 58.82 43.75 51.52 44.95 54.17 31.82 27.15 47.11 45.34 43.01 39.85 43.33 32.67 43.71 54.4 42.25 40.05 51.75 45.71 44.87 46.88 42.34 48.28 42.37 35.17 51.39 43.48 42.86 37.1 57.69 40.22 43.53 30.77 42.65 39.49 44.05 35.14 41.38 52.94 37.14 50 37.25 28.3 100 48.89 54.76 47.22 29.31 NA 37.88 38.2 50 39.81 41.18 45.16 41.38 50 NA 19.05 26.32 17.86 39.23 47.25 35.06 40.58 39.58 50.74 50.6 71.43 46.59 40.54 41.96 45.45 37.14 42.22 32.63 37.65 47.13 37.4 52.54 37.21 42.25 58.41 16.16 0.000594 0.028421 N cassette RBL1 chr20 - chr20:35695525-35696388 chr20:35695525-35695635;chr20:35695701-35696388 chr20:35695636-35695700 NA 100 100 62.07 100 NA NA 21.43 100 NA 78.95 NA NA 54.55 53.49 NA 54.55 100 100 NA 76 100 100 64 56.25 NA 100 56.25 72.22 100 66.67 NA NA NA 100 50 82.76 100 68 40.91 NA 100 NA 100 NA 100 NA 62.5 100 100 80 41.67 NA 81.82 68.75 100 100 NA 64 100 100 47.37 62.5 65.22 69.44 23.08 NA 59.26 63.33 55.56 100 46.15 68.42 43.33 100 100 53.85 100 57.14 53.33 9.09 44.44 70 42.86 64 NA NA NA 100 73.33 NA 48.89 NA 100 100 NA 100 75.86 65.38 100 100 50 NA 48 66.67 56.25 100 NA 56.25 100 NA 100 66.67 NA 50 48.48 100 75 NA 100 NA 52.17 65.62 NA 58.06 NA 100 55.56 69.44 100 100 NA 60.61 31.25 100 NA 100 NA 100 100 41.18 100 100 68.42 100 NA NA 56.67 NA NA NA NA 50 50 41.67 65 50 50 81.48 50 63.16 NA 72 NA 100 NA 100 NA 74.19 43.33 62.5 NA 72.11 49.45 -22.66 0.001257 0.027852 N cassette RC3H2 chr9 - chr9:125618158-125620947 chr9:125618158-125620201;chr9:125620373-125620947 chr9:125620202-125620372 100 100 100 100 100 NA 100 100 100 100 100 100 100 90.16 100 100 92.86 100 86.21 57.58 87.5 100 100 100 100 100 100 100 100 100 100 100 100 100 73.21 83.87 100 100 100 86.05 100 100 85.71 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 87.14 92.65 100 100 100 91.36 100 100 100 90.38 86.96 100 91.4 100 93.33 100 91.38 91.76 100 90.67 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 85.45 100 100 100 100 100 100 100 100 100 91.01 100 100 100 100 100 100 91.07 100 84.91 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 89.58 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 86.08 100 100 100 100 86.96 100 90.16 100 100 100 76.6 100 100 100 100 100 100 100 100 100 88.56 -11.44 0.000228 0.009112 N cassette RHOBTB3 chr5 + chr5:95067789-95084036 chr5:95067789-95072592;chr5:95072780-95084036 chr5:95072593-95072779 100 NA 100 100 100 NA NA 100 NA NA 100 NA 100 NA 100 NA 100 100 100 NA 100 NA 100 100 NA NA NA NA NA NA 100 100 100 100 NA NA NA 100 100 81.48 NA NA NA NA 100 100 NA 100 100 NA 100 100 100 100 100 100 100 100 100 100 NA 89.36 NA 100 100 100 100 100 100 80.85 100 NA NA 100 100 100 100 100 100 100 100 100 NA NA 100 100 100 100 100 93.49 NA NA NA 100 100 NA NA 100 100 NA 100 NA NA NA 100 NA 100 100 NA NA 100 100 100 100 95.54 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 NA NA 100 100 100 NA NA 100 100 NA NA 100 NA 100 100 100 NA 100 100 100 NA NA NA NA 100 100 100 100 100 100 92.06 100 100 100 100 100 NA 100 100 100 100 100 100 100 86.77 -13.23 0 0 K cassette RICTOR chr5 - chr5:38947544-38949813 chr5:38947544-38949457;chr5:38949530-38949813 chr5:38949458-38949529 NA 31.91 22.95 33.33 7.69 NA 37.25 38.46 14.29 23.81 12.9 NA 21.21 17.5 15 20.83 18.92 26.83 18.87 NA 24.24 NA NA 28.57 NA 0 18 43.75 21.21 23.26 19.15 21.05 0 11.76 20.59 36 9.68 26.09 20.93 33.33 7.89 22 25 29.03 9.09 23.53 NA 25.58 15.15 24.56 10.71 34.48 15.79 27.27 19.05 14.29 28.33 4.35 21.05 13.33 31.25 18.37 6.38 17.39 18.18 5 22.58 22.5 31.25 22.37 19.05 20.34 14.29 23.91 11.36 25 24.69 11.36 9.68 47.22 8.82 10 17.86 42.11 28.57 15 18 22.5 21.95 11.54 9.52 43.33 31.43 33.33 20 37.04 20.75 17.39 17.31 33.33 37.5 24.29 8.33 16.67 26.76 19.35 21.74 13.33 36.67 16.22 23.81 18.6 22.02 NA 20.93 19.61 11.11 31.25 3.7 25.4 22.62 17.46 16.13 22.54 22 27.27 20.69 35.71 12.5 19.75 35.29 5.26 0 27.27 34.78 NA 20 24 36.36 15.38 NA 4.76 NA 31.43 30.56 24.32 20.83 25 15.38 NA NA 6.67 21.74 22.73 30.43 28.12 13.33 31.71 19.35 42.86 28.21 20 18.18 22.22 28.12 NA 28 35.48 15.79 22.64 7.14 18.52 20.93 35.24 14.31 0.00144 0.030738 K cassette RIPK2 chr8 + chr8:90770462-90777568 chr8:90770462-90775056;chr8:90775211-90777568 chr8:90775057-90775210 NA 69.35 100 37.04 100 60.87 8.64 80.43 56.45 100 100 100 70 84.09 100 63.64 55 80 100 100 74 100 66.1 60.47 81.25 66.67 79.07 51.28 69.39 82.69 67.09 79.59 NA 70.21 100 27.27 76.6 70.27 78.08 27.91 72.73 75 66.04 100 70 58.23 60.42 59.38 62.79 72.86 69.7 35.05 71.43 72.11 70.31 72.73 39.53 100 100 74.51 65.79 100 69.31 66.67 64 73.53 75.68 60.53 57.61 53.66 65.45 58.06 73.53 66.67 61.39 76.6 57.14 71.05 100 61.22 62.07 77.5 100 50 76.04 69.7 66.67 56.41 42.53 69.64 100 32.86 80 86.11 64.94 80.49 84 49.46 68.97 36.36 78.02 62.79 76.12 68.85 41.67 52.17 63.27 65.71 44.44 64.29 58.97 51.02 68.29 78.26 54.55 70.45 78.57 39.24 59.18 78.05 38.86 68 66.67 43.3 63.64 44.9 79.49 NA 52.31 70 84.29 100 70.97 75.68 100 100 70.59 100 66.67 100 57.58 100 100 59.57 100 58.41 100 100 NA 59.46 100 54.95 69.86 73.33 47.17 75.76 100 58.82 59.52 37.74 75.68 70.97 72 81.08 49.28 57.69 79.59 70.91 67.5 80 70 65 70 33.95 -36.05 0.000082 0.004235 N mutually_exclusive RNASEN chr5 - chr5:31515327-31521229,chr5:31521323-31526185 chr5:31515327-31515560,chr5:31515672-31526185 chr5:31521230-31521322 chr5:31515561-31515671 NA 16.67 5.26 53.85 5.88 NA NA 33.33 100 47.62 NA NA 53.33 0 39.13 27.27 56.67 7.14 50 NA NA NA 7.14 39.39 90.91 29.41 4.76 NA 9.09 10 58.33 42.31 NA NA 10.53 0 36.36 36.36 0 0 72.73 10 20 9.09 NA 38.46 NA 42.31 38.46 52 51.52 0 50 32 37.93 70.83 NA 47.06 43.75 45.83 42.86 42.31 NA 64 30.3 NA 48 45 30 0 20 28 32.26 38.71 NA 45.45 11.76 42.86 9.52 34.78 NA 38.46 42.86 50 57.89 NA 3.57 25 34.38 40.48 NA 0 0 NA 0 NA 78.26 31.03 43.33 32 55.56 29.17 54.55 NA 34.62 25.71 35.29 0 21.43 50 13.33 31.58 65.91 NA 37.93 44.44 27.78 37.78 57.89 51.72 37.14 41.67 64.71 34.78 25 33.33 53.85 5.88 20.69 65.22 6.25 NA NA 55.56 38.1 36.84 0 9.09 11.76 NA NA 6.67 75 29.03 9.09 30 NA 6.25 NA 34.62 NA NA 33.33 46.43 54.17 52.63 46.88 36.36 48.39 15.38 40 11.76 21.43 12.5 58.82 NA 56 52.63 41.18 30.77 39.29 26.32 36.84 0 -36.84 0.000254 0.01128 K alternative_acceptor RNF111 chr15 + chr15:59383354-59384735 chr15:59383354-59384711 chr15:59384712-59384735 chr15:59384735-59384736 33.33 25.97 24.07 18.75 29.73 NA 40 100 22.64 14.29 20.37 100 20.83 23.26 10.34 16.67 68.75 14.81 31.43 0 29.41 11.76 10.53 28.57 13.04 24.24 15.62 25.71 26.67 33.33 27.78 22.73 NA 22.73 29.63 38.89 18.18 20.41 30.3 42.31 25 43.75 25.81 11.54 6.82 25 17.39 18.6 24.32 25 26.92 38.89 27.27 26.67 41.18 36 30 29.03 22.73 37.14 35.71 25.81 32.5 34.29 33.33 27.03 12.9 25.81 29.03 39.47 42.86 23.53 23.81 33.33 28.57 32.14 34.62 29.55 23.33 26.67 38.89 33.33 36 21.74 28 11.54 7.41 24 31.03 34.62 23.81 31.03 29.03 26.47 32.14 20.75 28.57 28.57 37.93 30.77 21.74 26.32 34.78 31.58 26.47 35.48 21.57 24.24 25.53 18.75 23.81 16.67 28.12 11.11 21.74 21.74 14.63 25 8 30 32.35 34.04 42.86 29.03 36.11 34.78 33.33 18.92 22.73 25 0 22.22 11.54 17.07 18.52 37.5 29.03 18.52 46.43 17.24 15.79 18.18 0 21.88 17.24 26.56 23.08 25.81 31.82 13.04 NA 34.29 28 26.47 15 26.19 33.33 27.78 36.67 43.75 17.86 37.78 16.67 33.33 38.46 37.5 23.81 24 26.32 41.38 38.89 38.1 26.32 39.18 12.86 0.000645 0.030348 K alternative_acceptor RNF216 chr7 - chr7:5781276-5792476 chr7:5781447-5792476 chr7:5781276-5781446 chr7:5781275-5781276 36 30.68 59.26 57.41 32.94 50 62.5 60 45.34 39.05 41.18 100 48.72 52 41.56 40.74 24.03 50 27.94 39.53 41.67 44.64 43.42 32.65 31.08 48.65 42.86 40.7 33.33 37.78 54.05 35.53 51.43 33.8 58.44 19.05 37.04 27.61 33.96 15.89 46.55 48.39 41.67 28.92 51.56 22.14 35.85 37.68 25.84 42.11 50.81 27.91 45.95 42.22 45.45 44.16 56.96 44.21 41.1 35.78 38.14 40.7 51.14 36.54 37.36 41.25 32.91 30.12 31.91 23.17 50 43.1 21.26 31.53 35.43 42.7 43.3 41.46 43.86 28.81 53.7 46.4 36.9 35.53 43.75 42.65 50.62 49.23 37.25 37.33 52.63 33.8 38.18 44.9 23.76 42.31 47.06 34.95 29.73 40.43 37.88 33.96 32.95 33.33 42.86 30.26 41.57 29.41 32.39 39.13 29.67 41.18 31.48 35.62 28.97 34.78 28.07 41.96 45.31 35.48 33.87 36.36 32.39 40.94 34.31 36 36.36 45.95 34.69 44.57 48 49.28 35.8 44.21 51.11 36.9 30.86 44.26 32.1 40.35 47.5 61.7 40.43 30.12 49.02 38.97 40.74 28.72 26.09 30 NA 64.58 29.82 35.53 50.49 46.36 45.12 40.96 36.28 13.04 36.84 56.86 24.24 37.11 63.53 18.81 26.92 42.67 30.58 42.45 44.59 35.71 40.43 21.11 -19.32 0.000213 0.015537 N cassette ROD1 chr9 - chr9:115030476-115060111;chr9:115030476-115060120 chr9:115030476-115038123;chr9:115038294-115060111,chr9:115038294-115060120 chr9:115038124-115038293 100 90.67 86.51 100 100 NA 100 89.47 84.86 100 86.39 100 82.52 90.83 100 82.11 72.67 84.21 86.79 85.94 83.41 100 100 87.78 100 100 84.16 100 89.44 90.58 82.59 76.62 100 75.45 91.49 75.23 83.56 86.59 85.04 67.52 88.89 92.35 83.94 93.48 100 82.47 100 85.29 90.48 85.33 80.79 83.08 88 80.52 83.54 100 100 100 86.21 84.29 79.19 92 87.06 83.82 81.02 85.11 78.63 92.11 88.89 76.4 91.92 73.91 85.23 89.8 85.94 88.46 83.96 79.82 84.16 84.51 89.58 89.22 89.26 90.41 84.88 92.52 73.83 86.61 82.7 91.58 93.64 80.62 82.55 93.1 85.95 91.2 87.9 81.78 74.83 86.42 87.29 82.43 100 87.13 87.3 82.95 86.25 85.5 81.48 93.5 83.33 83.5 85.83 94.74 91.15 79.57 88.04 75.74 100 84.26 80.28 94.77 87.5 85.04 85.88 76.54 87.18 90.57 87.5 94.04 84.8 90.91 85.28 100 100 100 86.05 94.19 87.13 100 90.14 89.93 100 86.99 90.6 87.36 100 80.95 89.41 100 100 88.89 79.59 100 92.63 86.29 86.52 83.02 83.96 77.78 87.26 85.44 83.33 77.23 87.5 100 85.59 82.52 83.74 86.61 100 86.11 87.22 77.09 -10.13 0.000271 0.010236 K cassette RPRD2 chr1 + chr1:150413500-150415706 chr1:150413500-150414356;chr1:150414435-150415706 chr1:150414357-150414434 11.76 64.71 50.72 59.09 60 NA 38.46 70.59 58.93 52.94 61.36 NA 62.86 64.29 50 48.84 74.14 57.81 60.34 51.35 65.91 69.64 53.01 53.85 60.87 66.67 57.14 56.36 43.86 62.5 51.43 51.79 57.58 100 80 82.61 52.54 57.14 67.27 75 63.16 55.93 68.75 61.9 56.25 28.57 70.59 51.56 51.52 60.87 47.44 73.17 56.1 46.83 50 76.67 55.93 72.5 50 42.86 44.62 70.27 72.5 40.28 55.77 64.29 47.92 55.56 39.53 57.53 51.28 44.44 45.61 44 59.65 39.62 68.75 58.93 57.14 68.29 60.87 37.04 48.65 46.51 52.73 43.4 62.96 66.67 67.92 39.47 61.9 81.13 62.96 50 55.56 75.56 58.06 71.43 40 57.89 77.08 54.93 49.06 64 56.86 40.3 54.67 51.9 48.65 65.85 56.1 66.67 54.24 65.96 54.29 57.33 47.69 45.98 39.47 53.26 34.88 51.52 64.58 45.65 40.62 44.44 32.43 100 64.62 58.46 59.38 72.41 62.92 54.76 60.47 65.31 68.85 72.73 56.36 37.93 62.22 72.73 100 58.62 73.68 46.43 52.63 52 60 53.19 NA 48.94 65.45 60.61 66.67 42.86 67.39 76 64.81 80.39 61.54 75 33.33 55.77 80.65 66.67 59.21 57.45 44 61.02 57.58 58.14 57.14 77.69 20.55 0.001306 0.028484 K cassette RPS24 chr10 + chr10:79797063-79800372 chr10:79797063-79799961;chr10:79799984-79800372 chr10:79799962-79799983 82.68 47.14 49.56 79.41 57.21 78.24 47.75 54.83 36.24 85.59 38.96 51.28 68.87 48.66 47 87.76 58.12 71.38 64.64 33.47 33.7 38.17 32.36 36 46.24 24.19 48.6 30.54 66.01 65.3 44.91 72.43 55.63 45.77 36.41 18.29 66.24 61.24 39.69 44.8 74.34 89.89 72.35 64.32 39.13 85.58 37.01 50.97 53.48 70.22 30.18 5.39 58.08 61.18 66.25 33.48 36.54 88.03 72.25 41.23 72.73 79.73 54.46 63.16 35.3 71.6 83.04 62.87 37.64 24.43 40.53 77.83 59.28 82.22 58.9 42.21 49.45 39.14 78.92 66.77 86.66 69.72 66.51 29.43 29.01 75.87 69.29 77.68 51.78 42.88 30.69 9.9 81.89 44.53 60.51 48.19 79.99 45.8 74.83 74.48 75.69 35.18 20.5 54.7 90.38 87.02 67.77 74 47.21 60.54 70.88 64.18 70.12 38.11 53.23 74.95 63.96 25.59 38.79 51.27 80.74 70.72 37.17 75.38 34.82 63.3 24.02 76.18 39.71 60.88 61.23 70.99 43.9 76.15 36.33 18.17 51.82 66.4 50.61 51.23 58.9 66.56 75.02 63.41 61.26 70.95 76.06 60.76 59.31 30.17 48.5 66.41 58.75 65.34 68.04 34.52 83.41 66.6 91.71 26.43 58.08 83.31 60.86 80.21 71.86 63.9 62.5 83.11 64.18 77.71 71.1 79.2 61.18 21.36 -39.82 0.0002 0.00817 N alternative_acceptor RTCD1 chr1 + chr1:100752760-100755183;chr1:100752760-100753991 chr1:100752760-100756958 chr1:100753992-100755183;chr1:100755184-100756958 chr1:100755183-100755184;chr1:100756958-100756959 76.14 61.36 70.95 27.78 61.87 69.35 37.44 60 60.47 74.63 67.5 NA 42.55 66.06 78 41.76 45.1 52.81 68.75 89.58 68.92 59.72 66.67 60.87 67.96 61.29 66.37 46.53 59.41 67.47 70.37 67.31 65.62 56.82 74.26 47.5 57.94 73.68 70.33 31.88 54 47.31 70.73 72.44 64.89 61.29 76.27 65.55 67.89 55.66 74.66 38.75 60.26 52.55 64.41 57.89 42.86 63.38 65.33 60 41.38 45.78 67.89 65.48 53.09 43.9 47.62 33.33 53.12 39.44 48.57 37.93 64.36 46.58 62.3 63.29 46.48 63.24 55.74 50.85 48.61 50 53.12 39.26 56.12 62.5 60.81 62.2 46.74 64.36 67.82 33.78 47.89 63.22 58.62 58.9 46.32 62.39 56.47 35.21 64.42 65.81 82.58 61.25 34.21 50 63.56 51.85 64.35 66.34 67.74 62.73 42.86 65.62 73.08 46.48 57.3 70.56 62.5 55.37 48.15 68.85 55.14 64.42 60.71 69.23 72.46 56.63 58.43 53.92 80.92 70.37 71.97 41.33 73.56 78.01 64.96 57.73 58.1 60.64 54.37 59.83 73.21 58.02 58.93 70.43 49.06 57.53 62.96 81.63 85.04 56.99 55.95 56.31 52.05 60.81 54.17 34.78 50.72 41.77 64.21 71.7 65.38 64.94 49.21 70 63.29 64.37 67.92 61.76 44.44 68.83 61.29 39.09 -22.2 0.000224 0.016117 N cassette RTCD1 chr1 + chr1:100739009-100741154 chr1:100739009-100740379;chr1:100740522-100741154 chr1:100740380-100740521 100 85.33 90.74 61.54 85.23 82.86 68.75 88.89 90.54 100 100 100 77.42 100 100 90.54 68.63 83.02 91.89 100 92.75 100 100 100 91.86 72.22 100 91.14 84.72 92.41 91.03 87.72 100 100 89.77 67.74 92.31 89.39 100 73.17 100 81.63 85.45 100 100 100 100 89.87 82.05 90.8 100 67.44 89.36 92.13 78.05 82.35 100 100 100 100 91.23 80.95 81.94 86.36 87.8 87.27 86.44 84.62 92 69.77 86.3 100 79.55 81.36 86.49 89.33 80.49 84.62 86.79 80 85 100 83.64 90.28 100 68.89 100 100 87.1 100 100 61.7 87.5 100 83.82 100 70.91 100 90 100 94.39 100 100 100 76.79 100 84.06 100 88.14 100 87.88 89.29 78.85 100 100 85.19 83.12 92.13 100 92.39 79.76 87.34 77.27 100 86.24 100 100 100 78.57 100 100 100 100 100 100 100 89.74 71.79 100 100 78.72 100 100 100 85.33 87.5 100 81.82 100 100 100 100 84.38 85.25 80 100 79.17 84.78 75 78 93.24 100 85.51 100 100 100 87.14 100 90 100 77.14 100 91.89 68.75 -23.14 0.000039 0.002304 K alternative_acceptor SCAF4 chr21 - chr21:33057488-33057710 chr21:33057554-33057710 chr21:33057488-33057553 chr21:33057487-33057488 46 56.9 55.56 51.28 63.04 75 62.67 73.44 51.76 60.71 49.23 100 63.41 52.63 61.4 51.22 65.22 48.15 45.57 76.92 62.71 51.61 51.56 64.06 67.44 59.65 64.29 66.25 58.33 52.73 61.9 54.72 32.39 44.44 70 52.78 59.38 57.83 60.29 47.83 68.18 78.72 63.46 65.38 78 36.76 47.76 59.46 55.56 56.6 51.06 47.22 52.38 51.25 55.84 63.46 57.45 58.44 56.6 50 61.19 54.55 60.34 62.86 50 65.08 52.05 50.72 61.64 47.37 62.2 53.33 44.93 62.07 69.81 54.84 53.45 56.18 58.14 56.1 61.54 53.33 59.26 59.02 55.05 52.63 54.39 58.16 60 57.58 78.79 42.59 53.7 66.07 68.93 66.67 72 42.31 55.32 57.89 48.98 62.96 55.17 80.36 60.42 55.13 55.05 40.4 60.26 59.38 49.06 61.36 52.94 60.47 58.46 60.92 46.23 52.48 65.08 63.49 74.58 77.05 63.74 60.61 48.24 52.7 65.31 55 50.59 71.43 57.14 51.79 64.81 54.24 58.14 48.15 56.34 64.58 55.71 52.78 56.52 56 75 54.65 53.7 56.45 63.89 50 64.44 43.33 100 57.14 61.02 71.43 59.42 73.81 65.52 59.65 68.85 28.4 63.49 56.86 54.1 69.64 66.67 52.38 69.49 60.71 52.44 55.77 72.46 55.17 58.14 47.3 -10.84 0.000451 0.025896 K cassette SCARB1 chr12 - chr12:125263133-125270902 chr12:125263133-125267228;chr12:125267358-125270902 chr12:125267229-125267357 100 100 93.86 64.79 89.13 63.04 56.76 87.72 100 100 100 100 100 100 96 100 92.13 91.11 88.24 100 88.1 100 100 93.9 100 64.71 100 100 85.42 100 85.42 89.29 100 100 100 63.41 100 100 82.35 65.38 100 100 92.54 100 100 91.21 92.86 100 87.27 89.04 100 72.86 89.23 93.08 83.33 88.68 100 100 100 87.64 87.64 100 73.33 100 88.78 100 89.71 86.96 100 61.54 100 100 93.55 87.5 100 94.25 100 82.28 92.96 87.5 100 86.54 92.65 87.23 87.69 60.61 100 86.08 94.06 94.34 100 80 93.42 100 92.86 100 100 67.91 91.35 92.31 87.93 87.72 94.05 82.93 90.59 100 90.91 92.06 91.67 100 100 86.21 80 100 83.87 89.84 84.62 100 76.36 100 87.69 100 89.8 86.44 100 78.1 100 100 84.44 100 100 100 100 100 100 100 100 100 90.2 100 76.92 100 100 81.44 100 100 100 90.74 100 100 100 100 93.15 75 87.23 100 87.3 100 84.09 78 75 100 87.14 86.84 50 100 100 93.51 89.33 89.13 74.58 82.61 94.05 69.12 -24.93 0.000085 0.004328 K alternative_acceptor SEC13 chr3 - chr3:10342832-10345709 chr3:10343059-10345709 chr3:10342832-10343058 chr3:10342831-10342832 100 100 93.5 100 88.7 100 91.08 100 83.22 100 92.11 100 91.84 100 97.3 100 91.58 100 92.43 100 89.32 92.92 90.35 86.4 90.43 95 92.17 83.41 90.09 91.67 92.59 100 88.28 95.26 100 87.5 94.16 90.52 88.11 88.18 85.48 100 93.39 100 90.91 95.33 92.19 86.72 88.19 100 90.24 78.05 89.3 100 92.37 86.47 89.89 83.33 90.68 95.5 100 91.27 89.32 100 89.74 90.65 95.65 93.88 85.81 84.8 85.71 100 93.08 100 90.45 90.27 88.54 86.62 92.5 91.47 95.54 100 100 90 89.25 100 100 92.31 93.89 88.85 100 80.72 100 100 88.73 100 100 91.61 95.57 95.38 92.69 90.65 91.86 92.74 92.91 85.26 91.35 96.25 94.4 100 90.78 86.74 100 100 93.64 89.89 100 91.26 100 100 91.34 87.21 95.27 90.38 90.78 100 90.38 100 89.6 100 100 100 85.98 100 100 93 90.38 87.78 92.39 100 100 100 87.32 92.96 93.33 90.67 90.44 92.47 100 91.96 100 100 90.6 95.21 93.63 93.98 93.67 86.51 93.48 78.89 88.57 93.01 96.43 90.52 94.95 87.67 100 96.6 86.9 91.75 94.44 89.03 92.91 82.76 -10.15 0.00011 0.008619 K coord_cassette SEC31A chr4 - chr4:83778918-83784470 chr4:83778918-83782783;chr4:83782862-83783686;chr4:83783726-83784470 chr4:83782784-83782861;chr4:83783687-83783725 50 17.72 35.03 31.97 47.27 50 54.84 51.47 38.71 71.91 26.57 NA 62.71 33.7 46.31 80 40 52 43.24 37.25 16.67 15.58 31.52 52.94 42.86 26.09 35 26.79 31.46 32.22 50 52.69 36.96 45 35.06 73.44 47.42 45.05 31.82 78.95 37.21 67.42 32 46.88 52.63 62.07 50 64.49 63.46 62.89 36.13 56.9 69.09 47.72 28.35 46.27 41.9 67.07 48.28 52.27 45.9 52.11 20 41.67 56.25 35.53 61.18 51.61 43.55 73.53 28.87 71.76 60.71 64.04 20 34.78 48.68 34.57 62.65 44.44 60.34 36.84 29.07 38.46 65 36.64 59.09 64.84 55.86 33.98 32.65 63.22 52.27 33.06 35.24 16.67 33.33 35.16 45.98 76.19 66.91 39.1 36.45 36.07 60.8 67.07 49.23 64.74 33.96 32.26 40.57 53.93 46.67 59.26 63.1 43.08 53.09 41.13 27.37 63.27 68.32 50 21.17 48.36 47.75 61.9 31.25 60.87 31.36 31.25 49.37 40.86 35.42 64.52 21.05 25.76 37.12 21.35 47.31 14.08 32.43 60 20.33 46.59 49.66 24.24 50 45.19 0 20 100 25.81 47.92 44.44 39.29 24.69 58.9 45.76 67.44 68.81 36.69 53.95 57.61 50 35.87 44.26 47.96 53.78 62.96 35.58 33.33 52.17 45.12 71.12 26.01 0.000358 0.01478 N cassette SEC31A chr4 - chr4:83778918-83784470;chr4:83782862-83784470 chr4:83778918-83783686,chr4:83782862-83783686;chr4:83783726-83784470 chr4:83783687-83783725 44.12 19.25 35.75 37.12 47.27 53.49 51.72 55.7 46.23 71.59 30.18 NA 60.87 33.7 48.39 80 42.2 49.47 48.13 45.76 25.38 19.75 33.14 59.6 46.67 25.55 37.5 31.75 35.29 36.46 53.47 47.62 30.95 48.24 41.45 73.44 49.5 48.45 35.9 78.49 42.55 65.73 38.18 45.16 50 51.52 52.38 66.96 64.81 63.27 44.04 57.63 69.64 52.09 33.58 50 49.17 65.38 46.32 55.79 43.48 52.78 32.53 42.73 57.36 37.18 58.23 50.98 41.09 70.27 31 66.34 60.71 60.87 27.5 37.01 45.83 36.56 61.25 45 59.65 41.94 35.79 41.18 65 33.06 64 67.01 56.64 39.82 36.54 70.64 53.33 38.17 34.21 25 35.92 32.14 42.86 73.68 68.35 42.18 41.38 40.91 60.14 59.55 48.23 65.41 37.5 33.33 41.12 54.21 48.09 57.69 61.58 47.89 51.28 38.51 34.91 66.04 63.39 52.63 27.52 50.78 47.15 58.44 36.05 63.27 36.72 32.65 48.39 41.49 38.41 65.08 22.08 28.47 38.06 21.35 45.56 15.28 29.58 56.52 20.33 47.96 52.23 32.43 52.38 44.66 0 30.77 100 33.01 45.05 44.44 41.88 32.22 60.53 51.35 65.43 73.23 37.59 47.19 52.78 48.62 37.23 44.26 47.96 52.76 60.53 35.58 33.33 54.92 45.8 71.94 26.14 0.000189 0.007856 N cassette SECISBP2 chr9 + chr9:91953496-91956261 chr9:91953496-91954778;chr9:91954869-91956261 chr9:91954779-91954868 100 100 83.54 86.79 86.59 86.05 52 100 71.43 100 100 100 100 100 100 100 100 90.14 100 100 100 100 100 100 100 100 79.49 82.69 100 100 100 100 100 76.19 69.84 72.5 85.92 100 89.36 85.71 84.91 100 100 100 86.11 85.71 100 89.55 91.94 100 100 82.93 82.69 100 90.2 88 75 100 100 100 100 100 82 100 100 100 100 100 100 82.42 89.33 100 100 100 87.1 90.38 86.41 86.36 100 100 86.49 100 100 100 100 100 100 78.72 84.72 100 100 71.01 90.38 100 100 70.59 100 100 100 100 100 100 100 100 90.2 100 100 100 87.5 89.06 100 87.88 88.3 100 89.23 79.1 100 80.85 100 100 91.94 100 89.19 100 100 100 81.82 100 89.13 91.67 100 68.42 100 100 100 100 93.18 100 100 100 100 83.58 100 100 79.73 100 100 100 100 100 100 100 100 100 79.59 88.89 86.44 100 86.57 80.82 100 90.91 100 100 88.51 100 100 100 100 83.33 100 80.49 100 81.62 -18.38 0.000075 0.003971 K alternative_acceptor SERBP1 chr1 - chr1:67889961-67890570 chr1:67890006-67890570 chr1:67889961-67890005 chr1:67889960-67889961 23.29 30.12 35.04 28.27 37.64 20.45 11.46 43.66 35.94 43.15 33.13 41.48 32.61 26.84 41.13 34.88 24.71 39.42 26.8 42.13 27.39 28.99 35.26 32.02 29.81 27.33 34.21 31.34 36.45 31.25 35.01 35.88 36.24 24.02 31.33 13.58 31.74 31.28 34.52 18.21 28.09 35.43 28.44 27.53 31.79 39.89 27.61 39.22 36.83 32.57 44.27 19.67 26.32 37.86 26.82 29.24 37.66 31.21 32.42 29.79 30.17 34.78 26.94 33.73 28.98 29.06 40.08 30.22 34.06 16.13 26.3 39.51 37.87 30.63 30.97 32.62 28.76 30.72 28.17 29.27 29.78 36.84 28.28 24.31 32.58 34.12 44.69 25 28.53 26.71 33.33 18.55 36.67 41.46 28.66 28.48 32.49 34.21 36.52 26.76 33.27 25.27 29.39 37.28 34.59 33.65 33.27 28.93 25.19 26.86 37.76 38.01 34.14 46.94 31.98 36.81 44.86 38.16 26.6 38.41 32.98 30 21.25 29.53 33.82 33.74 30.81 35.56 28.11 37.43 29.15 31.93 39.29 41.22 28.26 40.35 33.56 38.41 36.48 32.64 25.1 35.45 34.72 25.66 30.2 28.36 28.87 35.69 42.42 27.59 32.28 36.36 28.73 25.08 30.71 37.91 26.04 26.03 38.28 17.74 27.51 34.78 37.03 30.56 26.15 30.47 32.64 29.21 29.56 31.55 39.22 25.45 31.98 17.98 -14 0.000042 0.003859 N alternative_last_exon SERF1B chr5 + chr5:69322343-69325592;chr5:69322343-69359241;chr5:69322343-69337350 chr5:69322343-69328141 chr5:69359242-69359313;chr5:69337351-69338939 chr5:69328142-69328525 61.22 48.15 54.03 52.54 56.47 57.14 48.33 63.55 43.75 61.11 50 61.11 45.45 52.73 70.83 36.36 40.68 54.9 46.88 48.65 40 61.76 48.39 58.7 44.19 56.1 50 51.35 53.19 50 59.52 56.25 58.82 38 62.5 24.14 56.25 52.53 50 34.92 42.5 53.95 54 53.47 61.7 48.89 47.06 57.14 63.29 57.69 66.67 43.59 50.85 54.72 61.82 64.86 62.32 50 49.25 37.78 53.42 47.17 53.33 48 51.39 50.49 47.27 51.43 55.81 38.64 35.42 49.12 52.87 41.94 48.78 57.41 46.94 52 46.15 52.24 51.39 54.76 53.12 47.62 56.86 55.12 69.57 65.62 47.27 60.32 42.31 40 41.18 60.38 47.83 50 58.33 51.79 54.44 24.14 59.38 54.05 62.96 48.65 59.18 46.27 58.24 45.65 50 47.5 57.69 56.9 51.06 55.43 58.62 50 49.12 48.8 55.56 58.54 47.46 61.25 50 56.82 51.72 38.46 50 41.18 46.67 57.45 66.23 50.79 62.07 63.29 44.12 67.86 47.73 38.89 47.46 64.29 57.97 53.16 63.51 40.68 59.3 48.48 62 48.84 55.05 52.94 66.67 66.67 49.09 62.86 44.12 46.67 53.85 37.1 32.81 26.67 47.83 58.82 50.65 52.83 60.61 58.54 52 44.44 44.44 52.27 50 55.36 52.27 36.78 -15.49 0.000127 0.021773 K alternative_last_exon SERF1B chr5 + chr5:70197761-70201011;chr5:70197761-70212767 chr5:70197761-70203560 chr5:70212768-70214356 chr5:70203561-70203944 64.44 50 54.39 53.45 56.41 56.67 48.15 63 46.67 62.12 50 68.97 41.94 53.06 71.17 36.67 38.89 55.67 46.67 50 42.86 66.67 51.72 58.54 41.67 58.97 51.43 51.52 53.66 51.85 57.89 56 59.38 36.96 63.04 23.08 54.67 53.33 50 33.33 40 55.56 52.17 53.85 63.64 50 45.65 55 61.43 58.33 65.62 44.74 50 54.9 62 62.86 61.54 48.48 47.62 34.15 53.03 46.94 57.14 55 52.31 50 47.06 51.52 54.76 37.5 32.56 50 50.62 41.38 47.37 56.25 46.67 52.38 41.1 50.79 50.72 53.85 48.28 48.65 55.32 53.39 68.18 65.52 49.02 60.34 43.48 41.67 42.55 62 45.24 52.63 60.87 49.06 58.75 25 61.47 54.55 64 50 59.57 46.77 58.14 43.37 50 47.22 60.87 56.36 50 55.81 58.18 49.09 47.17 47.41 55.17 58.33 48.15 60 48 56.1 50.63 37.84 48.15 41.38 46.15 57.78 64.86 49.15 62.26 65.33 45.16 70.37 47.62 38.89 48.15 69.23 59.09 52.11 62.86 40 58.54 48.28 64.44 48.78 55.45 57.69 66.34 68 47.06 64.06 42.62 48.28 54.17 33.93 31.03 28.57 47.83 59.26 51.47 52.08 59.32 56.76 52.27 47.76 41.67 47.37 48.98 54.9 52.27 35.41 -16.86 0.000186 0.026966 K cassette SETD4 chr21 - chr21:37429503-37431113 chr21:37429503-37429681;chr21:37429776-37431113 chr21:37429682-37429775 NA 0 9.09 0 0 0 5.56 NA 0 5.56 0 NA 11.76 0 0 5.88 12 14.81 0 NA NA NA 0 9.52 13.04 0 0 0 18.18 5.56 5.26 6.25 NA 0 7.14 7.14 3.12 0 0 29.17 NA 0 21.43 0 NA 0 0 3.03 5 0 3.12 27.78 6.25 0 0 6.25 0 4.88 0 0 19.05 4 NA 4 3.7 0 13.64 0 6.67 17.95 9.09 0 3.03 16.98 7.14 0 0 0 0 4 NA 5.56 NA 9.09 3.85 3.7 5.56 3.12 0 0 0 35 4.17 11.76 6.67 5.56 9.09 14.29 6.98 5 5.88 6.67 4.76 7.14 29.73 24.24 10 10 5 0 9.52 0 4 0 0 4.17 0 10 0 15.79 0 3.7 0 21.21 0 3.45 0 NA 0 0 4.17 0 0 5.26 0 6.67 0 5.56 4.17 NA 0 5.56 NA 0 2.94 11.54 0 4 NA NA 0 NA 6 0 5 16.67 3.23 0 12.5 30.77 0 4.76 0 5.26 0 26.32 4.35 4.17 0 3.57 0 5.88 3.7 28.48 24.78 0.000077 0.004059 N alternative_acceptor SETDB1 chr1 + chr1:150900451-150902473 chr1:150900451-150902442 chr1:150902443-150902473 chr1:150902473-150902474 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 85.45 100 100 100 100 100 100 100 100 100 100 100 67.86 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.57 100 76.67 100 100 100 100 89.33 100 100 88.1 100 100 100 100 100 100 100 100 100 100 100 100 100 73.08 100 100 100 100 100 100 100 100 100 100 100 100 92.75 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.55 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 89.47 100 100 100 100 100 100 100 100 100 100 100 100 100 81.06 -18.94 0 0 N cassette SETDB2 chr13 + chr13:50057099-50062425;chr13:50057099-50059765 chr13:50057099-50057599;chr13:50057700-50059765,chr13:50057700-50062425 chr13:50057600-50057699 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 75.86 100 100 100 75.61 100 100 100 100 100 100 100 100 100 100 93.06 100 84.09 100 100 100 100 100 100 100 100 100 68.57 100 93.9 100 100 100 100 86.67 83.72 100 92.13 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90.74 100 100 100 100 100 100 100 100 82.89 100 100 100 100 92.19 100 100 100 100 100 100 100 100 100 100 100 87.23 92.31 100 100 100 100 88.33 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.89 100 100 86.27 100 100 100 100 100 100 100 100 89.58 100 100 100 100 86.47 -13.53 0.000002 0.000162 K cassette SETX chr9 - chr9:135140373-135145001 chr9:135140373-135144789;chr9:135144877-135145001 chr9:135144790-135144876 34.15 11.24 31.48 33.75 34.07 50 38.46 42.86 33.58 21.92 20.83 0 47.69 22.56 59.09 32.14 30.1 36.27 28.91 32.39 24 15.31 16.94 25.29 44.66 21.1 44.05 42.96 35.65 21.17 28.16 34.33 36.11 29.55 22.69 52.38 32.97 31.03 45.19 49.46 50.68 31.36 27.01 30.21 41.43 37.8 36.84 38.46 29.03 37.04 19.55 56.9 38.46 33.63 22.09 25 36.71 26.42 16.67 26.82 23.17 55.17 47.15 40 25.45 45.45 20.43 35 29.71 36.24 24.44 24.22 27.78 25.77 34.29 22.66 31.97 30.25 19.82 21.5 48 20.29 13.75 37.7 21.37 29.03 21.05 38.18 32.98 22.5 45 37.66 26.79 28.04 24.6 21.67 22.92 37.89 13.89 34.48 24.36 32.52 30.3 36.52 40.46 24.43 26.47 24.19 33.52 22.89 19.55 35.59 13.91 27.27 21.14 29.79 33.91 22.11 27.38 17.99 33.93 29.59 18.06 42.47 39.58 27.47 34.62 24.53 32.59 28.21 20.75 11.67 17.81 26.79 32.14 16.67 32.08 52.17 40.79 32.94 29.17 26.15 18.84 23.75 30 30.41 32.08 17.5 NA 30.48 36.73 40.24 30.91 41.56 52.17 20.62 30.95 37.08 23.1 54.55 22.43 27.71 24.21 36.19 31.51 38.57 35.29 30.59 33 22.77 51.85 37.68 30.27 50.92 20.65 0.000663 0.017248 K cassette SFI1 chr22 + chr22:31924850-31942846 chr22:31924850-31927043;chr22:31927116-31942846 chr22:31927044-31927115 NA 54.17 46.67 65 54.55 68.18 38.1 64.52 55.56 46.34 58.33 100 70.97 55.88 60.61 57.41 54.17 59.26 47.37 NA 64.52 48 48.39 62.5 73.33 NA 40 66.67 48.98 40.38 45.76 48.48 29.41 57.14 54.55 100 66.04 56.82 61.54 81.67 57.14 51.22 63.16 55 45.71 41.03 56.52 62 62.86 56.67 53.57 70.83 44.83 70.83 75 53.33 59.26 69.62 58.7 56.82 63.64 70.83 57.69 100 56 58.06 58.06 57.14 49.09 77.19 54.55 70.83 63.04 48.39 46.43 61.54 55.17 62.07 55.1 48.89 56.25 51.22 51.85 41.03 60.98 35 51.43 52.73 47.73 40 NA 100 50 100 63.33 100 52.94 31.82 50.88 60.53 52.5 50.94 46.15 64 54.9 58.33 40.43 40.35 50 NA 41.86 63.33 62 56.67 63.16 54.55 61.54 50 100 59.31 47.37 58.14 50 53.19 44.83 48.57 45.16 52.17 51.85 100 44.19 100 43.59 65.38 NA NA 46.67 52.38 58.97 53.33 44.44 60 100 56.76 69.7 47.06 65.38 65.38 NA 100 100 52.08 62.79 45.95 50 58.33 54 58.97 67.39 57.14 46.67 68 66.07 48.15 62.86 76.19 51.06 56.25 54 60 52.78 41.67 55.56 79.43 23.87 0.001732 0.035493 K cassette SFRS18 chr6 - chr6:99862567-99873090;chr6:99862563-99873090 chr6:99862563-99864224,chr6:99862567-99864224;chr6:99864305-99873090 chr6:99864225-99864304 88.71 70.95 89.13 47.04 82.49 63.89 88.24 90.85 94.96 87.5 79.31 100 91.1 79.01 74.83 78.34 90.91 85.46 91.33 100 82.83 82.95 83.9 81.05 83.19 64.38 78.43 90.51 89.23 90.29 80.77 87.5 81.87 86.67 87.5 64.55 82.65 84.29 85.92 71.22 80.43 83.5 83.01 91.03 77.95 76.19 83.17 89.9 86.83 84.86 84.91 77.3 83.19 79.67 67.55 84.26 86.89 88.96 100 86.49 85.54 88.74 95.24 87.73 91.09 77.12 87.45 90.05 91.94 79.79 85.25 85.63 93.24 87.09 84.89 87.1 87.98 81.89 85.98 87.74 94.25 87.85 68.94 90.27 82.99 62.58 82.88 87.99 85.8 87.85 85.61 70 82.65 88.67 87.58 82.11 75 62.43 82.65 90 88.99 91.04 92 88.69 86.83 85.76 89.28 86.32 91.53 69.52 84.95 89.44 64.8 100 80.62 90.94 75.41 79.22 86.55 89.04 88.14 85.82 70.28 86.75 89.01 81.63 88.24 88.21 88.09 74.71 89.69 91.77 84.4 89.22 91.46 100 85.66 90.32 88.09 74.17 65.18 85.52 78.53 89.32 86.34 86.45 90.48 77.14 76.71 87.32 100 90.91 85.09 67.39 85.64 85.37 91.63 85.9 81.16 67.93 90.13 87.18 83.97 80.25 62.5 84.69 86.67 84.33 89.37 88.66 81.37 83.77 86.32 70.61 -15.71 0.000889 0.021558 N alternative_acceptor SH2B1 chr16 + chr16:28878355-28878694 chr16:28878355-28878651 chr16:28878652-28878694 chr16:28878694-28878695 100 100 83.64 100 88.37 100 94.3 100 100 100 87.5 100 100 100 100 100 100 100 92 100 100 100 100 100 89.47 100 100 100 90.28 100 100 100 100 100 100 100 88.73 100 100 82.54 100 100 100 100 100 100 100 100 100 92.22 100 82.61 100 100 100 100 100 89.09 100 89.47 89.16 100 100 100 91.14 100 100 100 90.14 86.9 100 100 100 91.46 84.09 86.11 100 100 100 100 90.2 100 100 100 90.91 100 100 100 93.27 91.3 100 82.76 88.46 100 89.61 100 100 87.27 86.47 95.74 91.03 93.9 94.06 100 100 93.51 91.72 100 100 100 91.75 100 100 100 100 91.25 90.54 100 100 100 87.84 100 100 100 100 100 100 100 89.36 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 87.5 100 100 100 94.12 100 100 100 100 91.38 100 80 100 100 100 100 100 88.89 100 87.84 89.66 90.32 100 100 100 82.69 -17.31 0.000037 0.003494 K cassette SLC12A6 chr15 - chr15:34548485-34551013 chr15:34548485-34549842;chr15:34549990-34551013 chr15:34549843-34549989 NA 94.44 93.33 78.89 80 NA 20 84.78 100 100 100 100 85.71 100 100 91.07 75 100 85.51 100 100 100 78.95 82.05 NA 100 100 83.82 100 93.33 90.82 85.11 100 100 100 68.09 100 90.28 88.71 68.97 70.97 91.07 81.48 87.1 85.29 93.33 100 92.68 87.5 89.69 100 61.11 100 80.88 82.14 80.39 66.67 100 91.67 89.36 90.41 100 68 86.84 89.47 100 100 79.12 100 71.67 81.97 89.25 94.39 100 85.06 100 79.27 75.38 100 100 100 100 100 82.61 100 100 100 92.31 86.32 100 100 67.5 100 100 100 88.89 87.29 74.03 100 90.57 91.43 86.96 100 80.39 75.26 90.7 93.68 90.67 100 64.81 92.71 89.23 80.47 88.89 94.78 88.17 94.78 93.15 100 100 87.27 88.19 78.63 100 88.52 100 100 77.33 75.41 79.67 100 100 100 100 78.95 100 87.14 100 86.9 82.05 83.87 100 100 89.71 100 84.93 100 100 100 100 NA 100 88.14 100 80 100 100 72.29 90.11 81.01 88.89 100 100 100 64.1 NA 100 100 87.78 92.55 84.38 100 93.33 68.53 -24.8 0.000094 0.004613 N alternative_acceptor SLC25A40 chr7 - chr7:87485667-87487945 chr7:87485705-87487945 chr7:87485667-87485704 chr7:87485666-87485667 NA 4.76 2.44 3.57 0 NA 0 5.71 2.2 0 8.45 0 0 8.11 6.67 0 4.76 8.2 3.08 0 5.56 0 1.8 9.52 NA 10.96 4.76 5.06 4.88 2.94 0 0 8.33 6.67 4.44 18.18 0 4.04 2.5 16.67 0 9.84 3.28 2.56 0 4.55 0 10.53 5 5.56 5.49 17.54 0 15.94 0 10.81 5.41 9.62 0 0 5 0 0 4.76 9.52 0 7.41 7.55 10.2 14.81 5 0 2.9 0 5.71 7.55 3.23 10.87 3.85 8.2 0 8.51 0 0 9.86 0 5.13 7.89 3.7 9.18 12.5 17.91 3.45 14.29 10 9.09 16.67 17.5 8.96 11.43 4 5.15 7.14 7.41 3.45 0 3.39 8.77 0 0 16.22 0 5.71 2.78 4.26 4.8 8.11 0 12.5 9.23 0 3.53 8.65 2.99 3.77 0 7.14 10.53 2.17 15.15 6.35 0 10.68 0 7.69 4.35 3.7 7.41 0 9.09 1.96 13.51 0 0 0 5.77 8.33 9.52 5.13 0 NA 10 3.39 0 10 9.09 4.08 0 6.67 28.21 10.45 0 2.99 0 9.09 0 4.35 3.7 9.52 3.7 6.06 4 4.55 17.73 13.18 0.000036 0.003409 N alternative_acceptor SLTM chr15 - chr15:59192080-59193458;chr15:59192083-59193458;chr15:59191909-59193458 chr15:59192137-59193458 chr15:59191909-59192079;chr15:59192080-59192082;chr15:59192083-59192136 chr15:59191908-59191909;chr15:59192079-59192080;chr15:59192082-59192083 61.54 45.65 66.67 50 68.33 60.44 59.09 62.2 76.29 63.92 69.81 NA 57 73.39 70.43 54 54.61 64.22 67.8 96.92 55.03 63.64 64 61.61 62.21 67.19 61.29 68.25 77.31 68.87 62.42 61.54 59.72 78.18 70.23 44.95 62.59 70.27 65.28 55.92 68.46 66.25 64.84 69.13 70 72.41 55.28 65.71 54.97 62.96 69.05 45.52 60.42 60.15 41.53 46.79 58.46 56.36 73.5 60.61 68.66 72.52 75.97 68.35 70.2 60.58 79.21 64.35 66.21 47.33 63.23 75.96 71.11 61.27 67.67 71.32 53.66 65.65 59.59 62.89 73.02 60.67 65.83 68.52 58.97 90 61.22 54.44 63.56 72.57 59.38 33.87 52 60 66.15 58.18 59.09 67.65 56.36 52 61.76 61.25 64.46 60.91 65.42 79.61 62.14 69.77 52.63 58.62 63.64 70.53 54.31 37.5 70.54 63.33 83.85 71.97 59.09 63.03 76.7 66.91 61.31 61.11 74.12 71.15 66.92 64.62 57.35 66.22 65.28 68.89 71.43 58.82 60.38 54.72 56.7 73.81 66.22 52.63 65.71 69.57 56.72 69.77 72.41 63.4 76.36 51.39 NA 60.92 79.01 96 55.3 53.85 69.34 54.74 59.55 55.47 56.33 37.43 63.16 67.8 74.62 63.78 45.45 51.52 61.88 55.81 57.49 64.15 51.49 73.77 63.64 45.23 -18.41 0.000109 0.008619 N cassette SNAPC5 chr15 - chr15:66786891-66789979 chr15:66786891-66787667;chr15:66787758-66789979 chr15:66787668-66787757 100 100 100 100 100 NA 100 100 100 100 100 NA 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 85.29 100 NA 100 100 100 100 89.06 100 76.92 NA 100 82.76 100 100 73.68 85.29 100 100 100 100 100 100 100 100 82.76 100 100 100 100 100 100 100 100 100 100 100 100 100 51.43 100 100 100 83.33 100 100 100 100 100 87.5 100 100 100 100 100 100 34.62 100 84.62 100 NA 66.67 100 100 83.33 100 100 86.49 84.62 100 91.23 100 100 100 82.35 100 87.27 100 100 100 100 100 100 100 80 100 100 72.22 100 100 100 100 100 83.33 100 100 100 100 85.96 100 100 100 100 100 100 100 100 100 100 100 100 100 100 80.85 100 100 100 100 100 100 100 100 100 82 100 100 100 100 100 73.68 100 100 100 100 100 100 100 100 88.1 100 100 100 100 75.3 -24.7 0.000096 0.004703 N alternative_acceptor SNHG5 chr6 - chr6:86375866-86387141 chr6:86386910-86387141 chr6:86375866-86386909 chr6:86375865-86375866 100 100 100 68.18 NA NA 72.22 100 NA 100 100 NA 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 NA NA NA 100 100 100 100 100 61.11 100 100 100 62.79 NA 100 100 100 100 66.67 100 100 100 100 100 66.67 100 100 NA 100 100 100 100 NA NA 100 NA 72.22 100 100 80.77 100 100 48.57 100 100 100 100 100 100 NA NA 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 NA NA 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 68 100 63.16 100 NA 100 73.91 100 100 100 100 100 100 100 100 NA 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 NA 100 100 NA 60 42.11 100 100 77.78 100 100 100 100 100 100 100 100 100 100 61.95 -38.05 0 0 N cassette SNX14 chr6 - chr6:86267779-86281854 chr6:86267779-86275049;chr6:86275138-86281854 chr6:86275050-86275137 100 84.72 67.82 72.34 80.7 100 100 79.73 79.17 78.26 88.57 100 72.5 83.13 75.44 100 82.76 85.25 81.67 100 82.72 62.79 100 71.11 80.95 100 100 78.26 85.71 86.36 78 69.44 100 100 74.14 100 100 72 100 100 84.62 72.13 82.35 82.69 100 80.43 70.97 79.17 80.95 72.6 75 100 100 81.93 70 81.58 100 78.57 87.5 72.34 85.96 82.93 81.36 88.89 79.59 82.93 78.72 74.14 85.71 100 76.27 83.67 81.36 80.95 77.27 73.33 75.93 78.95 73.85 89.8 79.49 74.42 80.56 74.51 74.65 100 100 100 88.89 76.74 100 100 79.49 100 77.59 72.22 83.67 67.74 88.37 73.08 88.89 82.42 87.76 100 88.52 84.62 81.82 76.09 76.92 100 70.37 87.8 75 100 65.22 71.43 84.09 81.63 71.11 67.86 76.32 77.59 69.23 100 66.67 77.27 73.81 79.49 76.81 100 80.95 66.1 77.94 100 71.74 66 100 77.27 78.57 71.74 100 63.77 100 77.78 100 81.4 100 100 100 100 100 100 76.12 79.07 79.59 82.69 81.13 82.61 64.44 100 75.44 100 82 74.36 83.33 76 77.27 73.68 81.36 80 100 64.86 80.95 100 19.05 0.001383 0.029839 K cassette SNX14 chr6 - chr6:86246643-86251702 chr6:86246643-86248555;chr6:86248583-86251702 chr6:86248556-86248582 60 43.38 34.78 80.85 48.91 50 24 48.96 35.87 41.86 35.71 NA 33.33 30.97 40.87 58.97 23.85 45.05 42.73 11.32 23.33 46.32 26.83 53.33 34.78 53.95 25.53 19.53 38.6 30.17 44 47.32 55 31.03 42.95 20 39.74 44.44 28.26 16.67 22.58 38.93 34.21 33.12 25.4 64.71 40.3 41.38 41.38 32.82 44.44 3.64 52.78 22.3 51.85 36.56 20.99 64.71 43.48 39.77 37.35 43.55 34.62 23.71 37.36 26.26 52.13 49.48 27.1 14.16 11.72 55.26 51.52 27.96 22.15 27.66 27.37 20.65 43.43 40.98 56.86 32.05 45.45 27.45 39.13 55.13 20.29 61.54 36.59 37.61 27.27 0 49.28 32.14 24.22 28.57 62.5 10.13 37.08 51.72 66.4 34.73 29.57 30.77 42.98 68.42 55.13 45.31 25.98 60.47 48.19 44.71 65.85 26.67 60.32 47.31 43.81 24.16 28.57 59.81 74.03 45.31 44.44 30 38.1 36.17 35.94 64.38 43.75 53.03 41.26 38.46 52.59 41.94 38.03 26.83 27.47 28.77 38.75 32.99 37.31 60.71 60 43.82 48 32.26 39.68 37.5 28.99 30 13.16 35.63 35 46.05 46.88 21.43 41.1 29.11 58.9 18.46 33.33 32.58 60.44 31.88 54.05 53.42 41.58 41.67 48.75 47.44 23.08 40.54 39.76 15.42 -24.34 0.000063 0.003488 N cassette SORL1 chr11 + chr11:121437823-121444949 chr11:121437823-121440865;chr11:121440980-121444949 chr11:121440866-121440979 100 96.8 100 90.78 100 100 100 100 96.89 100 100 NA 100 100 100 96.81 93.43 100 95.77 100 100 100 100 100 100 87.67 100 94.29 100 100 92.98 100 100 100 100 89.38 100 100 100 83.93 100 100 100 100 100 98.21 100 100 100 100 100 74.36 100 92.66 100 100 83.47 100 100 100 100 95.8 94.74 96.98 100 100 100 96.41 100 87.82 100 92.96 100 100 100 100 100 93.04 100 100 100 95.94 100 100 100 100 100 100 100 100 100 83.08 100 100 96.15 100 86.75 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 95.18 100 100 98.67 100 83.33 100 100 94.74 100 89.64 97.06 97.64 100 100 100 100 90.56 100 100 100 100 100 100 100 100 100 100 83.58 100 100 100 100 94.23 100 100 100 100 NA 100 100 100 95.6 100 100 94.81 91.2 93.73 100 100 98.34 100 65.22 100 100 97.69 97.75 100 100 98.63 100 85.88 -14.12 0.000001 0.000063 K alternative_last_exon SP100 chr2 + chr2:231371161-231375839 chr2:231371161-231372707 chr2:231375840-231375881 chr2:231372708-231372860 100 100 100 100 87.1 NA 100 100 100 100 100 100 100 79.49 100 86.96 100 100 100 100 100 100 100 100 81.82 100 100 100 86.11 100 100 100 100 100 100 71.43 100 88.46 87.5 80.77 100 100 80.65 91.43 100 81.82 100 84.21 100 100 90.2 100 100 100 100 84.21 100 100 66.67 83.33 88.89 100 100 88.89 100 NA 100 100 100 77.78 100 100 100 100 82.5 100 100 88.1 100 100 72.73 100 100 100 100 100 100 100 85.71 81.25 100 80 100 100 89.47 100 86.49 100 NA 100 100 100 100 100 100 85.29 100 84.38 100 100 100 100 100 NA 72.22 84 66.67 78.05 100 100 78.79 80.77 87.1 100 100 75 100 88 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.02 100 100 NA 100 100 100 100 100 100 100 100 100 100 82.14 100 100 80.95 78.57 100 72.22 100 100 100 100 100 78.57 100 80.38 -19.62 0.000206 0.027295 N cassette SP110 chr2 - chr2:231033954-231036781 chr2:231033954-231035336;chr2:231035478-231036781 chr2:231035337-231035477 NA 45 65 20.45 100 20 NA NA 46.94 NA 48 NA 46.94 69.44 65.38 69.44 37.74 55.17 45 NA 52.63 NA 63.33 57.58 52.7 30.61 100 40 60.42 46.67 51.46 57.89 NA 23.08 58.33 67.24 60 52.38 50 71.43 40 72 57.63 58.82 56.67 68.18 26.32 60 52 50 41.94 53.33 57.89 56.52 45.9 37.5 34.29 59.38 60 57.41 54.05 38.1 40.74 65.22 59.26 47.06 100 36.11 60.53 69.86 53.85 51.35 55.41 60.78 50.75 65 48.48 30.61 55 64 46.15 60.87 54.55 46.67 47.37 38.46 62 54.17 57.58 50 53.57 100 NA 38.1 55.56 58.14 39.29 45.95 59.26 52.94 50 47.06 35 33.33 55.56 62.5 67.31 41.18 37.25 23.81 48.48 52.94 29.67 52.38 70.83 44.12 51.85 55.56 100 52.73 58.06 51.22 40.43 55.56 61.54 42.86 44 71.79 50 40 42.86 NA 63.64 54.55 55.56 NA 46.15 44.44 55 50 50 NA NA 48.72 NA 44.04 37.5 55.17 NA 48.89 NA 62.96 66.67 27.27 30 58.33 61.9 61.54 52.94 73.81 60 35.48 63.04 62.5 16.67 57.5 50 45 52.63 35 26.67 NA 52.63 70.65 18.02 0.001291 0.028296 K cassette SPTAN1 chr9 + chr9:131371564-131373992 chr9:131371564-131371929;chr9:131371945-131373992 chr9:131371930-131371944 25.81 52.86 32.48 68.85 32 30.61 22.64 28.57 43.37 71.88 31.93 NA 36.76 28.26 20.69 70.19 25.56 50.65 38.86 0 22.37 41.03 26.09 27.27 62.03 15.22 29.33 31.25 36.76 36.36 36.05 28.17 27.27 40.22 38.24 17.31 30.38 25.61 27.12 23.48 28.99 51.25 21.43 10.71 40.54 30.63 32.47 32.95 51.72 47 47.12 5.88 37.4 50.51 62.69 40.91 26.79 47.06 28.38 29.25 36.19 59.57 25 39.71 35.4 33.96 50 35.06 34.21 17.97 39.09 55.94 57.64 49.06 35 25.93 37.01 45.1 18.46 24.32 30.91 54.35 55.81 28.57 22.95 32.93 75 54.55 32.84 15.18 0 2.99 52.38 42.11 39.39 47.17 66.67 24.68 32.79 39.62 44.44 18.67 15.12 56.52 61.04 55.08 36.19 24.11 33.04 54.72 46.07 45.78 58.39 40.74 36.73 53.57 65.38 14.91 18.37 43.94 42.37 29.69 27.36 50.39 30.56 25.81 21.95 14.29 23.38 56.63 21.62 20.59 60 66.67 9.09 26.15 40 17.39 27.27 25 51.92 23.08 100 39.02 26.92 20.29 36.67 27.87 NA 16.9 0 26.87 14.86 34.67 22.69 37.31 31.11 29.31 63.41 13.04 38.32 27.14 49.38 43.01 55.56 48.33 23.53 33.6 36.75 48.78 14.75 41.86 34.67 15.17 -19.5 0.000352 0.012243 K alternative_acceptor SRP19 chr5 + chr5:112200430-112203100 chr5:112200430-112203068 chr5:112203069-112203100 chr5:112203100-112203101 17.11 17 21.51 61.4 23.48 69.33 65.96 34.72 22.22 30.65 20.55 NA 37.78 25.71 22.41 30.56 32 33.33 19.66 17.07 19.15 14.29 19.12 30.43 39.76 26.98 13.83 30 30.56 12.77 25 28.57 18.67 24.66 19.1 36.17 29.27 24.26 32.94 54.76 39.02 34 20.69 21.9 23.53 24.44 20 37.5 34.62 26.42 25.37 42.25 17.14 30.3 32.61 30.43 38.1 22.81 27.66 16.95 32.69 21.74 27.4 23.44 28.81 35.19 22 34.33 35.29 52.63 30.88 28 21.05 28 23.21 20.34 45 26.56 25 31.58 30.51 14.29 27.27 42.86 18.42 34.92 0 32.2 32.81 25 16.95 53.19 21.05 24.14 29.58 18.03 26.32 40.62 26.09 23.53 17.88 28.07 20.54 30.95 37.68 30.67 21.6 22.12 28.43 26.56 20.43 30.14 40.98 13.89 22.41 37.04 15 20.35 27.27 39.39 38.46 30.17 34.62 44.76 26.58 22.45 23.91 31.58 24.79 51.43 14.29 10.81 15.93 23.44 10.61 9.46 28.79 33.9 9.84 26.32 32.69 20.78 25.45 33.85 30.3 30.3 33.85 21.57 39.66 7.38 9.68 21.1 38.89 30.97 45.61 20.83 17.07 40 23.53 52.5 23.71 28.41 21.05 24.05 67.92 26.97 18.52 21.25 24.69 18.97 37.5 28.38 26.32 52.56 26.24 0.000196 0.014404 N alternative_acceptor SRRM2 chr16 + chr16:2819286-2820352;chr16:2819286-2820361;chr16:2819286-2819675;chr16:2819286-2819862 chr16:2819286-2819628 chr16:2819629-2819675;chr16:2819676-2819862;chr16:2819863-2820352;chr16:2820353-2820361 chr16:2819675-2819676;chr16:2819862-2819863;chr16:2820352-2820353;chr16:2820361-2820362 27.85 32.1 26.85 29.35 39.57 33.45 39.55 28.48 36.48 38.93 33.26 28.43 28.72 29.68 28.57 35.23 35.48 27.02 32.54 54.71 37.71 34.08 32.22 29.8 36.34 27.19 30.67 38.49 35.14 38.56 27.9 31.45 29.84 24.31 46.49 39.89 30.4 31.76 29.86 42.16 37.01 18.35 32.72 35.93 28.77 24.29 26.99 39.12 33 42.02 32.65 37.37 28.98 23.81 31.99 33.74 30.58 46.74 31.13 29.27 43.39 29.85 42.29 26.19 27.64 34.11 30.16 35.72 37.72 44.76 30.85 25.6 36.17 27.68 36.17 35.09 34.92 40.73 33.57 29.38 26.32 26.38 23.05 37.14 32.66 30.74 27.22 36.18 27.39 22.62 46.84 49.32 28.9 28.25 41.43 35.05 37.32 22.75 29.12 26.33 28.89 37.72 30.52 38.57 26.07 29.78 28.78 29.77 37.77 15.09 33.09 31.82 31.22 36.46 40.85 31.08 27.02 37.34 32.28 33.87 33.38 32.88 31.65 31.92 35.88 28.3 36.36 40.11 31.98 33.8 28.66 22.75 16.09 33.33 40.13 25 32.17 36.21 27.4 24.78 27.91 35.8 40.78 29.04 28.57 41.87 37.57 38.38 12.05 59.9 12.76 37.61 32.71 29.13 32.86 31.42 30.38 32.41 52.42 41.89 27.6 27.06 31.6 34 39.69 32.16 28.91 24.12 28.73 26.79 29.28 28.42 31.65 42.02 10.38 0.00039 0.024443 N cassette STAG3L1 chr7 + chr7:74990730-74994523;chr7:74991359-74994523 chr7:74990730-74993901,chr7:74991359-74993901;chr7:74994026-74994523 chr7:74993902-74994025 68.22 64.38 71.43 63.38 66.06 40.89 43.3 63.88 58.89 75.72 69.75 63.13 69.11 68.95 63.86 74.24 55.74 71.23 58.13 81.82 58.71 68.75 57.67 65.39 62.77 53.37 76.19 52.45 65.74 67.52 55.65 63.99 67.95 56.48 67.57 53.33 67.85 63.11 53.03 51.57 53.6 68.87 64.23 71.48 58.04 69.81 58.19 49.71 58.3 64.17 62.39 44.21 57.64 59.22 48.84 54.82 52.79 57.05 63.62 64.2 62.27 53.93 55.47 56.63 60.2 62.57 73.29 62.2 60.13 56.9 64.85 65.68 64.61 69.02 60.11 64.37 56.78 45.85 65.28 66.46 48.56 58.81 55.6 53 57.77 64.66 66.1 56.49 59.75 59.95 73.55 53.15 69.78 62.77 66.83 61.48 72.73 42.75 68.51 77.29 75.02 63.75 62.59 61.4 63.62 72.84 72.2 73.17 66.49 61.42 68.38 60.21 61.8 67.65 66.27 63.58 70.9 77.45 64.86 71.3 70.32 62.24 61.36 61.02 70.69 61.16 58.33 68.48 62.61 53.59 76.03 60.88 73.54 76.02 63.64 68.59 62.56 62.05 65.5 61.25 58.63 74.3 67.33 64.37 65.44 65.12 58.48 73.99 70 63.57 67.49 70.27 67.3 64.69 45.44 56.74 70.07 53.49 58.89 53.05 56.34 64.11 68.5 54.19 48.56 60.68 66.59 68.22 61.98 63.45 58.62 59.08 63.58 53.1 -10.48 0.000538 0.014969 N cassette STAG3L3 chr7 - chr7:72470383-72474167;chr7:72470383-72473543 chr7:72470383-72470880;chr7:72471005-72473543,chr7:72471005-72474167 chr7:72470881-72471004 69.21 67.7 71.2 69.48 71.22 45.36 53.04 66.43 61.31 75.82 74.27 72.41 69.46 74.89 67.81 75.83 60.83 70.93 68.71 77.42 68.57 71.3 59.22 67.85 67.29 57.69 74.51 57.99 71.05 69.88 60.81 70.46 67.38 63.44 70.06 54.03 65.94 67.77 58.61 56.09 53.53 73.25 67.03 72.37 59.02 74.65 61.07 54.81 63.56 67.99 65.27 47.4 63.5 62.58 54.02 57.95 52.56 61.54 68.98 67.37 66.85 57.36 60.27 61.09 65.37 65.52 74.77 67.7 67.41 61.35 70.33 69.63 68.22 70.49 65.33 66.2 61.82 50.16 67.99 75.83 54.33 66.74 61.08 55.85 62.46 67.11 70.88 59.47 68.91 65.03 71.35 51.24 72.94 63.3 69.96 63.64 73.63 49.46 73.24 77.25 78.1 70.76 67.64 68.56 66.84 76.97 77.17 77.88 68.45 62.42 72.31 64.05 67.14 66.67 73.25 69.06 73.04 80.31 66.15 73.44 73.57 68.38 64.95 66.14 73.88 68.87 62.61 70.11 69.37 56.28 75.43 61.98 76.96 77.73 70.23 71.98 64.14 63.95 68.79 61.7 61.9 75.37 69.49 69.63 68.7 71.74 65.68 78.42 76.38 74.03 69.48 69.05 72.47 68.83 49.41 59.53 75.64 58.22 62.71 54.96 61.13 69.67 72.91 59.96 53.23 67.14 69.53 68.28 66.06 65.63 64.61 62.05 67.85 54.5 -13.35 0.000365 0.012443 K cassette STAU2 chr8 - chr8:74601049-74650518 chr8:74601049-74621266;chr8:74621398-74650518 chr8:74621267-74621397 NA 18.52 27.27 20 40 8.33 14.29 35.42 18.18 36.36 33.33 NA 41.18 34.78 10 31.58 17.19 31.36 28.24 8.57 25.49 18.75 50 27.78 31.58 18.52 31.91 25.81 38.1 37.5 23.29 19.05 11.76 25.71 20.63 58.33 25.49 25 25.42 27.78 20.83 16.67 19.35 34.78 15.38 33.33 23.53 27.69 36.36 20.59 26.53 51.22 28.12 30 26.47 14.29 28.89 30.61 34.21 23.08 36.67 31.03 24 39.47 39.39 24.24 30.3 16.44 23.26 38.71 20.45 13.33 30.77 25 20.51 32 21.05 31.91 31.25 22.54 21.88 18.37 21.05 33.33 35.71 36.84 10.87 23.53 18.18 26.67 19.15 35.53 28.81 14.89 17.39 29.63 28 20 28.57 28.33 29.51 30.91 34.62 30.3 28.33 25 29.58 26.09 25.93 12.9 29.17 31.15 32.61 23.08 32 21.05 20 22.77 14.29 32 45.45 26.76 20.83 17.74 28.95 12.5 28.57 29.41 33.33 26.47 34.62 51.11 46.67 27.71 46.67 21.82 34.69 31.03 30.56 45.71 25 24.56 27.27 17.46 36.17 20.83 20 32.35 40 47.62 NA 15.62 17.74 26.83 25.53 30 40.3 18.18 31.71 41.38 25 25.33 28.36 12.5 11.54 27.27 26.53 18.33 26.39 24.32 34.29 27.27 27.05 40.05 13 0.001614 0.033365 K cassette STRAP chr12 + chr12:16035754-16042861 chr12:16035754-16036474;chr12:16036611-16042861 chr12:16036475-16036610 100 86.67 97.3 61.94 100 57.89 60.54 86.72 87.74 100 100 100 89.93 93.55 95.85 100 72.73 93.64 93.21 100 100 100 100 90.3 96 86.61 100 93.25 100 100 95.76 86.67 75.86 86.55 100 80.43 95.1 91.48 90.77 77.7 90.28 100 94.2 100 90 100 100 92.81 95.35 92.09 95.58 77.62 90.28 86.74 79.25 88.24 78.26 93.55 95.74 97.69 93.59 74.19 84.35 94.58 93.15 91.85 93.96 90.8 95.28 68.12 93.92 100 92.78 91.83 88.68 95.69 92.2 100 100 87.58 91.18 94.55 94 95.68 94.48 78.57 94.29 89.93 84.26 88.07 100 68.92 100 100 92.39 100 73.4 93.79 95.9 91.47 94.93 93.75 92.44 88.98 83.08 92.75 94.57 91.54 88.31 79.07 100 87.84 66.43 82.61 92.67 92.76 100 93.29 100 93.71 89.35 93.13 85.16 85.71 95.19 78.95 100 93.33 94.22 78.05 100 100 100 93.91 100 100 100 80 90.14 100 83.12 100 100 92.53 96.24 94.97 87.69 90 80.39 100 100 100 93.59 86.15 82.14 100 93.41 86.24 92.81 74.58 94.71 79.31 100 100 50.25 92.68 95.27 86.43 92.96 93.48 82.47 89.51 93.55 76.1 -17.45 0.000174 0.007394 N alternative_acceptor SUGP2 chr19 - chr19:19101959-19102148 chr19:19102045-19102148 chr19:19101959-19102044 chr19:19101958-19101959 100 100 87.5 83.33 84.09 72.73 75.16 100 100 100 80.77 100 87.88 100 71.15 87.18 87.5 83.33 73.85 NA 78.95 100 100 74.51 70.59 100 78.95 73.91 83.82 100 100 100 80.82 68.27 100 71.43 85.71 77.36 87.3 75.93 85.51 79.31 87.76 100 100 92.06 84.04 87.72 85.94 100 100 76.34 86.76 76.32 81.25 74.44 100 85.37 81.13 88.37 87.8 88.57 81.4 79.55 100 74.07 78.95 83.05 79.63 83.33 88.75 100 88.41 87.21 85.71 87.5 100 78.43 87.8 88.57 86.36 86.79 84.38 75.41 83.64 100 100 83.78 87.23 86.6 100 73.08 80.77 100 85.19 NA 100 87.27 90 86.89 88.66 82.22 74.03 84.71 93.58 82.14 84.57 81.48 82.8 NA 100 75 83.33 100 85.71 86.9 88.37 83.33 100 100 87.8 79.1 74.12 100 89.06 100 100 100 81.33 100 100 100 100 100 100 100 100 72.5 100 100 74.42 100 100 88 86.49 86.05 83.33 100 100 100 100 100 83.05 83.04 80 84 78.79 77.14 82.5 71.43 75.81 81.18 85.11 76.74 80 85.42 84 82.76 100 83.05 84.93 81.48 86.68 74.5 -12.18 0.000852 0.037287 N cassette SUSD1 chr9 - chr9:114804241-114814678;chr9:114804241-114814434 chr9:114804241-114804380;chr9:114804446-114814678,chr9:114804446-114814434 chr9:114804381-114804445 7.27 2.27 8.33 21.15 5.41 21.43 68.75 27.03 8 NA 5.48 NA 7.41 3.28 2.5 0 9.62 14.81 5.7 12 2.13 7.41 7.5 9.3 6.25 5.56 5.77 15.94 2.82 1.79 8.33 2.7 7.32 6.98 7.41 23.81 12.5 8.7 9.52 25.81 20.69 12.9 6.1 4.88 10.53 13.33 11.9 8.96 0 1.61 0 29.79 7.02 16.67 7.84 10.81 8.82 0 0 11.11 14.63 10 9.41 13.33 8.33 19.61 14.08 12.07 11.32 15.15 12.64 13.33 5 9.09 7.69 2.33 17.46 7.69 4.76 8.33 11.29 5 8 21.15 10.17 2.44 5.56 20 20.41 7.02 10.71 13.64 5.26 9.68 3.95 4.17 21.74 30.67 2.9 0 6.43 15.52 6.03 13.85 17.65 8.11 3.03 7 13.27 4.76 7.89 6.25 3.23 8 8.21 6.67 10.91 10.59 9.09 14.29 17.65 8.96 7.14 9.3 31.25 23.33 2.78 21.05 8.11 13.33 0 NA 11.43 11.11 8.82 5.06 9.09 14.29 17.39 9.09 8 7.58 5.88 8.51 4.55 7.08 20 2.78 NA 1.41 2.86 11.32 8.54 17.07 15.38 23.53 6.78 17.91 10.26 11.76 5.48 7.14 3.33 2.56 17.54 4.17 9.68 7.5 7.81 13.33 7.41 4.08 8.33 19.48 11.15 0.00178 0.036195 K cassette SYNGAP1 chr6 + chr6:33409537-33410665 chr6:33409537-33410229;chr6:33410272-33410665 chr6:33410230-33410271 NA 0 5 9.43 0 0 5.41 0 5.71 6.38 0 NA 14.1 0 0 4.11 0 6.56 0 0 0 NA 0 18.52 7.21 NA 0 0 0 0 11.9 7.32 0 0 0 14.55 0 10.29 0 17.72 0 0 3.64 0 0 0 0 13.71 7.75 2.44 0 18.18 11.11 6 17.52 3.77 12.5 2.83 3.92 6.67 3.3 0 0 0 6.56 8.33 0 6.33 14.29 12.41 5.88 4.17 5.63 10.26 0 7.14 13.95 4.69 4.17 6.5 0 3.64 0 0 7.69 0 0 8.11 15 10.59 0 13.04 0 0 8.08 0 12.5 4.88 0 10.29 6.25 3.7 0 6.67 15.33 22.39 12.87 5.49 5.71 11.76 0 0 9.59 0 12.5 10.29 4.39 6.61 0 0 11.93 4.48 0 4.08 11.54 10.24 8.57 0 0 8.57 3.64 0 0 0 0 0 0 0 0 0 0 0 0 6.49 0 0 0 0 0 0 0 0 5.94 0 0 0 7.02 4.08 9.71 6 0 0 6.9 0 11.84 14.29 8.96 0 8.45 4.88 0 0 0 13.79 13.79 0.000261 0.009902 N alternative_acceptor TAF1D chr11 - chr11:93471607-93472402 chr11:93471666-93472402 chr11:93471607-93471665 chr11:93471606-93471607 100 100 94.58 100 100 91.86 96.88 92.97 100 100 100 100 100 100 92.86 100 100 96.43 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 80.39 100 97.51 100 80.43 100 100 100 95.08 100 100 100 100 100 94.82 100 85.98 90.79 100 100 100 88.15 100 94.74 100 100 100 100 100 100 100 100 93.55 95.83 81.82 94.38 100 100 100 90.24 100 100 100 94.55 100 100 100 100 100 100 100 94.95 95.93 100 100 100 83.12 93.18 100 100 100 92.7 100 95.63 100 97.31 95.77 100 100 100 95.7 95.65 94.67 95.83 100 100 95.21 100 100 100 100 100 96.86 100 95.87 96.3 97.28 94.17 93.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 94.06 100 100 100 95.9 100 100 83.93 100 100 95.11 100 100 100 100 100 76.6 100 100 95.41 100 100 100 100 100 100 100 100 93.48 100 81.12 -18.88 0 0.000045 N cassette TARBP1 chr1 - chr1:234596143-234601401 chr1:234596143-234599582;chr1:234599681-234601401 chr1:234599583-234599680 100 83.61 93.24 84.55 88.24 100 NA 100 100 93.23 100 NA 100 83.67 100 100 85.92 91.89 84.13 100 100 100 100 100 100 NA 100 100 100 100 82.35 87.6 100 100 100 62.96 89.87 89.9 88 59.09 76.47 84.71 100 82.41 100 100 100 100 91.8 93.28 100 83.33 100 100 86.84 88.1 100 100 100 91.8 89.91 100 100 100 84.62 100 88.73 100 87.5 61.76 100 90.28 91.14 81.03 100 100 82.67 100 85.61 85.23 93.06 100 88.89 75.86 100 100 100 100 90.48 100 100 100 86.78 100 75.51 NA 83.82 81.44 100 100 100 83.08 100 85.29 90.27 91.26 81.76 93.84 100 100 100 100 87.27 100 84.93 91.59 100 100 100 95.89 100 91.46 100 83.95 100 86.11 100 82.42 100 76.74 100 87.85 100 88.46 100 100 100 100 100 NA 90.35 85.39 100 88.46 83.72 100 100 86.59 100 100 100 NA 82.11 91.8 85.39 100 90.71 80 90.7 75.36 83.05 76.56 100 87.5 90.62 100 88.37 82.86 87.13 93.75 78.08 87.5 100 69.16 -30.84 0.00154 0.032266 K cassette TBC1D14 chr4 + chr4:7008454-7012379 chr4:7008454-7011603;chr4:7011676-7012379 chr4:7011604-7011675 100 89.53 100 100 100 60 77.14 100 90.48 100 89.02 100 93.51 100 100 100 86.44 100 100 100 94.68 100 100 100 88.28 80.61 100 100 100 100 100 100 100 100 100 80.56 100 100 91.3 81.67 88.37 100 88.57 100 100 95.94 100 100 100 89.06 100 77.42 100 100 100 84.62 100 100 100 100 100 100 100 100 100 100 100 89.29 100 78.48 100 90.79 100 100 100 100 88.24 90.52 100 100 100 91.94 100 100 100 100 100 90 100 100 100 91.53 100 100 87.36 100 100 91.57 93.42 100 100 93.1 91.57 79.07 91.67 87.18 100 100 93.22 100 89.33 100 90.41 100 100 93.18 100 100 100 100 100 90 87.01 92.94 100 100 100 100 90 83.75 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 79.12 100 100 100 92.06 87.84 100 100 100 100 100 88.68 100 100 79.84 -20.16 0.000001 0.000082 K cassette TERF1 chr8 + chr8:73939288-73944276 chr8:73939288-73942570;chr8:73942631-73944276 chr8:73942571-73942630 31.25 14.81 66.67 42.42 46.51 7.14 36 51.22 15.15 58.97 48 NA 61.11 35.9 54.39 78.26 30.23 36.54 56.82 NA 10 0 24.32 56.76 44 23.81 22.58 31.82 31.25 31.25 56 64 10.81 13.33 52.38 100 31.25 27.08 45.71 62.5 38.46 59.46 8.33 37.68 4 51.85 35.71 43.18 42.11 52.17 43.33 67.65 NA 61.36 38.46 11.76 100 56.82 35.48 38.89 38.46 60 42.31 41.94 42.86 18.18 56 26.09 29.41 59.57 48.15 50 53.12 37.5 24.44 45.45 33.33 26.09 62.96 31.43 41.18 71.43 52.38 33.33 44.19 38.1 52.94 53.33 68.75 30.23 7.14 48.89 26.83 27.78 21.57 0 22.22 29.82 51.22 57.69 68.09 37.84 28.57 31.82 60.87 44.44 47.22 42.11 33.33 17.65 37.14 39.02 30.56 NA 30.56 36.54 33.33 21.21 22.5 50 24.44 39.39 6.52 64 44.19 27.27 50 50 37.5 41.94 59.65 33.33 18.37 36.84 20 23.08 45.24 42.31 31.82 0 24.14 33.33 33.33 30.3 48.57 25 60 33.33 17.95 16.13 NA 6.67 44.44 45.71 33.33 21.43 48.15 23.53 62.79 59.26 52.63 44 61.54 44.83 40 40 48 44.19 54.76 46.15 45.83 57.14 38.46 61.03 22.57 0.000836 0.020557 K cassette TFAM chr10 + chr10:60148580-60154117 chr10:60148580-60150524;chr10:60150621-60154117 chr10:60150525-60150620 100 84.72 100 62.86 88.1 57.14 78.57 83.13 77.27 100 100 100 100 84.31 91.79 100 85.71 93.33 82 100 90.57 100 100 89.47 100 63.64 100 83.33 100 100 100 100 100 100 100 74.36 91.94 88.57 85.29 85.42 100 100 85.42 100 100 100 100 93.98 100 100 92.86 81.36 100 87.3 77.27 100 80.88 100 100 100 100 100 100 100 86.67 100 100 100 88 87.8 88.1 100 100 100 87.04 100 100 84.78 100 100 100 100 100 83.87 100 100 100 77.5 72.22 100 100 72.92 100 100 81.69 100 75.47 83.12 100 100 100 89.55 100 100 75.93 100 100 100 79.17 100 100 100 80.56 100 100 100 100 80.49 100 100 87.76 87.5 90 86 86.21 73.68 100 100 89.29 88.1 90.52 100 90 100 100 100 100 100 82.76 100 100 100 100 100 100 89.8 100 90.74 65.62 100 100 100 100 100 81.4 100 100 100 90.91 90.57 100 100 100 84.85 76.6 100 100 100 93.06 100 100 100 100 83.39 -16.61 0.000893 0.021624 N alternative_acceptor TFB1M chr6 - chr6:155579043-155581406 chr6:155579217-155581406 chr6:155579043-155579216 chr6:155579042-155579043 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 78.79 100 100 100 100 100 100 88.89 100 100 100 100 75.93 100 100 100 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 75 100 75 100 100 100 100 100 86.49 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 90 100 83.87 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 83.78 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 89.36 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 89.4 -10.6 0.000002 0.000272 K cassette TFDP1 chr13 + chr13:114277602-114287434 chr13:114277602-114285937;chr13:114286060-114287434 chr13:114285938-114286059 100 92.71 95.83 91.81 85.37 80.7 100 92.56 89.27 100 92.12 100 100 85.9 90.26 92.98 90.95 93.46 93.75 94.44 92.02 88.41 91.87 92.16 100 84.97 90.64 94.54 88.81 87.32 86 93.26 100 91.02 100 81.21 91.53 91.89 92.61 76.69 82.69 100 95.15 92.23 100 91.1 93.29 90.17 100 92.7 88.43 80.72 91.43 85.71 100 94.81 100 82.06 95.05 91.7 91.33 91.75 89.1 100 93.01 82.14 100 91.6 90.51 84.11 89.21 93.48 94.86 94.15 86.67 87.5 93.24 94.55 90.27 91.84 89.77 89.31 93.82 93.45 90.36 82.61 79.03 91.09 94.82 90.6 100 78.57 100 88.89 88.24 100 73.26 87.78 82.38 95.51 89.77 91.81 90.52 100 88.11 88.52 93 89.56 89.67 87.62 92.76 90.48 92.57 93.1 94.79 91.07 85.14 92.59 88.64 88.68 92.86 90.36 88.22 85.55 88.31 88.39 90.29 100 94.21 100 92.47 93.79 94.5 NA 83.96 93.53 91.28 83.33 96.8 75.76 86.96 100 100 90.93 83.15 92.13 89.06 92.17 88.57 100 100 100 96.76 78.01 93 88.48 93.1 89.8 89.45 83.33 96.88 100 91.77 92.2 87.83 94.48 91.86 93.7 92.49 89.6 89.69 100 91.85 80.97 -10.88 0.000136 0.006204 K cassette TFDP2 chr3 - chr3:141724387-141811902 chr3:141724387-141772956;chr3:141772992-141811902 chr3:141772957-141772991 NA 19.51 19.61 34.29 9.68 31.82 0 18.75 NA 18.18 26.47 NA 28 12 38.1 25 28.89 18.09 24.14 0 NA 0 0 22 NA NA 0 23.81 20.83 42.11 27.27 17.65 NA 26.09 37.14 50 15.62 17.74 7.41 43.64 0 18.28 13.79 26.79 NA 17.86 NA 25 33.33 28.57 15.79 23.53 15.79 18.75 25 0 14.75 24.24 16.98 17.86 18.6 15.38 NA 32.43 8.11 29.03 20.29 17.24 28 38.1 20.83 20 20 20 37.5 17.39 26.67 26.92 17.39 19.05 32 28.26 25 0 20 26.92 29.58 0 23.08 11.11 0 41.18 7.89 0 17.95 NA 18.18 11.11 22.34 31.25 25 26.67 0 15.79 18.31 15.09 20 15.69 22.73 0 16.22 3.45 16.95 4 20 13.79 16.67 0 0 25.45 17.39 18.52 14.29 25 27.78 24 NA 21.88 33.33 30.43 27.78 9.52 13.16 37.21 20.83 0 0 20 17.39 NA 33.33 14.06 0 13.73 25 0 NA 31.25 0 NA NA 38.1 22.64 17.24 0 25 22.73 0 23.26 45.95 26.09 0 17.65 27.27 18.75 NA 6.9 24.32 17.57 21.43 20.59 13.04 18.75 42.41 23.66 0.000246 0.009528 N cassette TIMM23 chr10 - chr10:51613312-51623108 chr10:51613312-51620323;chr10:51620383-51623108 chr10:51620324-51620382 100 100 100 70 100 100 86.59 100 86.54 89.36 86.27 NA 100 100 100 88.64 85.42 100 91.94 87.18 80.39 100 100 100 100 100 91.07 86.36 81.08 100 89.13 100 100 100 100 80 90.38 88.52 100 76.32 88.14 100 100 100 100 78.26 89.83 86.49 100 86.96 86.11 84.85 100 90 100 84.78 100 100 92.86 100 100 89.86 100 100 100 100 91.8 85.96 100 100 90 100 100 82.69 100 81.82 100 100 88.1 91.67 100 84.38 100 100 88.57 100 100 91.46 84.48 100 100 87.8 89.06 100 100 100 100 90.91 94.19 100 100 100 100 100 100 100 100 93.02 100 100 83.61 85.71 91.53 100 85.94 88.46 100 84.62 100 100 100 100 100 87.76 100 88.89 100 75.86 100 100 100 100 100 100 100 88.46 100 85.94 93.33 100 100 100 100 90.38 100 87.04 100 100 100 100 100 100 100 100 87.5 100 88.57 86.84 84.62 81.08 100 100 90 100 81.63 100 100 81.55 86.44 100 84.78 100 100 82.97 -17.03 0.002435 0.045393 N cassette TMEM131 chr2 - chr2:98410017-98412680 chr2:98410017-98411392;chr2:98411579-98412680 chr2:98411393-98411578 100 100 100 100 100 100 57.78 91.4 100 100 91.6 100 100 90.91 100 100 100 100 91.06 100 94.12 100 100 100 91.67 100 100 90.83 94.23 100 93.14 100 100 100 86.63 77.61 100 94 100 85.92 89.8 100 92.45 91.74 100 95.05 100 100 100 94.68 100 89.23 85.71 100 100 93.24 100 100 93.33 89.42 91.01 88.89 100 93.55 100 100 91.25 100 100 71.54 93.81 95.05 90.48 100 100 100 92.96 94.74 100 89.33 100 100 100 100 100 100 100 94.05 100 92.86 79.63 86.11 100 100 93.26 100 100 93.97 91.86 100 88 94.89 89.91 100 93.41 100 89.78 94.85 94.17 100 89.41 100 93.1 100 94.62 100 100 88.89 100 100 100 90.29 100 93.1 100 100 100 100 91.15 100 100 100 100 100 100 100 100 89.06 100 100 100 100 100 94.39 100 94.63 100 93.94 100 100 100 100 91.67 100 90.77 94.19 92.96 85.51 88.54 78.49 100 100 100 84.62 100 100 94.87 100 90.6 87.25 81.48 93.51 100 82.2 -17.8 0.000014 0.000917 K cassette TMEM5 chr12 + chr12:64174955-64178749 chr12:64174955-64176320;chr12:64176485-64178749 chr12:64176321-64176484 NA 25 13.33 16.67 29.17 NA 17.39 18.18 NA 26.32 31.58 NA 5.88 35.29 8.62 NA 33.33 18.18 9.68 NA 17.24 NA NA 21.74 38.89 31.25 NA 7.14 15 28.57 17.39 14.81 NA 10 37.5 5.56 24.32 18.18 23.81 2.78 8.33 NA 32 31.71 26.67 19.05 15.38 34.69 29.63 32.43 22.58 9.52 20.83 32.61 17.65 7.14 NA 29.03 19.05 23.08 20.93 NA 18.75 6.9 16.67 32 27.03 31.58 35.71 4.26 20.83 30.77 34.48 31.03 23.08 24 NA 3.85 23.53 28.95 18.18 5.88 18.18 22.22 4.76 21.74 39.13 34.21 23.53 26.67 18.18 13.33 26.09 13.33 23.08 NA 20 17.95 28.07 37.04 40.74 30.77 28.95 12.5 16.67 21.88 24 30.14 29.41 7.14 14.29 26.09 11.54 30 38.46 40 25 30.43 27.78 45.16 13.89 20.41 32.14 39.13 13.33 33.33 6.67 11.76 44.44 NA 38.64 10.71 27.27 11.11 NA 12 8.33 7.14 16.13 NA 20 29.55 18.18 6.25 11.54 28.57 5.56 7.14 7.14 NA 22.58 NA 26.47 31.71 34.78 9.09 22.22 10 26.67 3.45 6.67 20 20.93 20.59 5.56 20 12.2 33.33 20.45 30.77 9.09 14.29 20.93 4.91 -16.02 0.000365 0.012443 N cassette TMEM55B chr14 - chr14:20927600-20928350 chr14:20927600-20927786;chr14:20927893-20928350 chr14:20927787-20927892 100 100 100 100 100 100 68.15 100 100 100 100 100 100 100 100 100 87.23 100 100 100 100 100 100 85.19 89.47 100 100 100 87.3 90.38 100 100 100 91.58 90.91 81.08 100 89.47 92.19 87.93 100 100 88.24 100 100 100 90.67 100 100 100 87.84 85.48 100 100 100 100 100 100 86.05 100 100 100 82.14 100 88 100 100 82.35 92.75 100 87.69 100 100 100 86.11 100 90.74 100 100 86.67 100 100 85 84.93 100 100 100 100 100 84.31 100 82.5 100 100 91.11 100 100 87.69 100 93.9 100 83.13 100 100 100 90.91 100 92.22 81.44 100 100 90 100 100 100 92.31 88.52 100 100 86.84 100 91.75 88.6 100 90.16 93.48 87.27 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 87.78 100 80.82 100 100 87.07 100 100 100 88.1 100 83.72 100 100 86.89 100 81.13 100 100 91.43 100 100 92.86 100 100 100 100 86.11 100 100 83.99 -16.01 0.000457 0.014065 K coord_cassette TMPO chr12 + chr12:98931351-98940136 chr12:98931351-98938219;chr12:98938316-98938728;chr12:98938840-98940136 chr12:98938220-98938315;chr12:98938729-98938839 40.48 64.67 75 75.19 59.63 100 100 82.8 65.89 60 77.73 100 79.45 62.75 67.97 48 82.26 77 73.81 100 75.47 50.89 73.85 77.88 81.25 63.92 62.55 84.17 64.29 58.47 72.57 64.89 53.26 64.58 65.22 85.85 71.31 79.53 73.25 86.87 100 67.69 62.11 64.57 59.35 44.05 82.69 81.94 69.7 73.12 64 84.16 81.97 82.43 65.96 73.97 73 73.08 71.15 81.82 76.47 76.09 74.1 77.62 75.41 88.31 73.33 67.21 69.11 86.84 73.2 68.18 75.19 83.23 73.18 71.9 70.24 82.28 82.46 62.26 83.33 89.29 77.4 88.64 77.88 57.58 64.13 79.37 83.45 74.26 69.14 82.47 70.21 89.62 59.38 80.43 70.87 68.6 84 91.25 73.96 80.2 85.29 76.06 86.32 63.64 67.44 69.64 70 73.24 57.58 75.93 76.53 77.46 46.1 72.82 63.09 60.36 80.72 65.96 68.33 73.39 70.06 80.49 81.45 77.92 76.47 82.35 73.17 78.57 63 83.33 65.81 68.97 63.16 78.7 72.09 79.69 89.69 72.15 67.86 79.35 100 79.63 77.78 73.75 100 83.52 66.18 42.11 50.62 69.44 81.2 88.71 78.65 83.76 80.39 76.71 65.54 87.05 73.01 57.14 65.47 66.67 81.11 71.93 76.07 81.82 84.78 82.69 81.25 75.47 73.96 86.34 12.39 0.001101 0.028056 N alternative_last_exon TNFAIP8L2 chr1 + chr1:151129199-151131118,chr1:151129199-151131168;chr1:151129199-151138946 chr1:151129199-151131141 chr1:151138947-151139017 chr1:151131142-151132225 92.62 85.71 76 52.63 87.25 56 59.62 91.49 80.89 87.15 76.66 74.58 79.23 77.25 100 87.76 69.47 91.3 92.27 66.67 74.61 83.97 74.88 84.4 84.62 75.38 86.08 69.75 78.16 81.5 80.77 85.61 100 91.35 80.81 57.32 88.73 85.27 73.91 65.87 78.38 100 76.53 88.89 89.27 96.12 71.64 81.33 85.71 92.56 86.38 55.63 82.35 78.05 82.98 87.5 80.65 83 82.35 72.16 80.95 85.53 67.07 81.98 81.25 82.98 76.99 80 80.89 62.2 81.82 68.87 84.69 85.82 77.64 75.75 75.71 83.44 81.42 76.09 78.79 90.76 87.25 89.74 84.34 76 75.64 74.07 78.79 73.61 74.21 61.02 100 76.3 79.1 78.74 77.55 82.35 92.55 87.86 86.09 79.35 79.64 81.45 90.83 91.86 88.68 87.1 84.46 71.76 89.62 83.33 87.63 84.68 82.74 85.71 80.29 85.05 78.65 88.37 85.71 73.3 83.27 67.05 86.27 80.5 80.75 82.35 69.03 100 80.35 100 83.46 100 90.48 64.93 73.46 76.32 77.59 91.46 100 85.06 91.96 82.46 90.91 75.81 91.8 84.26 100 78.09 100 69.6 85.09 73.42 72.46 82.97 76.92 81.2 72.06 64.17 82.03 98.91 86.96 86.9 66.67 71.3 75.53 82.89 87.88 89.09 85.37 79.57 82.35 61.61 -20.74 0.00006 0.021773 K alternative_acceptor TNIP1 chr5 - chr5:150410235-150411847 chr5:150410309-150411847 chr5:150410235-150410308 chr5:150410234-150410235 100 82.91 91.36 76.32 89.19 100 89.26 87.04 92.31 85.53 87.72 100 88.57 88.6 100 71.43 91.3 88.06 86.76 100 76.34 84.69 86.9 80.39 81.08 80.09 90.72 85.87 85.6 90.91 77.19 87.84 100 83.87 84.31 68.83 90.91 87.34 87.18 78.29 82.81 100 81.88 89.61 75.9 83.13 83.65 91.07 83.33 84.38 83.72 65.67 83.33 90.6 82.35 85.12 86.02 100 90.59 90.35 100 100 87.5 83.33 85.95 86.76 84.62 88.66 87.68 79.67 83.94 100 85.87 88.17 88.62 91.23 87 83.95 79.31 78.48 100 88.89 79.1 100 84.44 86.36 100 87.5 85.23 82.8 90.11 84.78 90.38 80.82 87.95 88.89 90.91 92.13 91 81.55 86.29 84.47 85.35 89.52 87.6 84.04 87.8 84.91 82.09 80 83.9 80.77 83.33 82.17 86.27 85.71 80.95 94.02 81.9 89.29 82.56 89.8 81.69 89.66 91.95 84.15 83.52 100 88.17 82.81 84.76 100 90.24 87.14 81.16 83.77 82.76 87.1 87.3 79.78 82.26 100 86.25 87.36 100 86.13 100 89.47 100 80.58 81.05 91.18 88.33 87.84 85.45 81.48 88.41 84.38 84.88 70.33 86.89 100 84.71 100 72.73 77.63 86.25 89.13 86.84 89.66 100 85.94 86.9 74.31 -12.59 0.000422 0.024927 N cassette TNRC18 chr7 - chr7:5399201-5401527 chr7:5399201-5401224;chr7:5401354-5401527 chr7:5401225-5401353 74.74 85.05 88 79.49 68.06 73.86 42.56 74.36 85.39 85.92 86.61 79.45 78.82 82.72 79.67 79.34 82.93 81.97 80.89 83.12 86.02 75.61 87.12 81.07 84.85 100 100 81.67 88.24 92.59 82.61 78.47 87.5 86.31 75.34 100 82.4 80.25 83.07 92.28 80.74 73.68 87.15 86.08 100 85.26 86.9 83.33 87.03 90 81.31 100 81.62 72.65 87.18 91.24 77.27 81.19 87.95 92.09 84.54 89.19 87.34 79.22 90.61 83.49 87.13 77.14 91.19 84 87.16 84.11 91.11 85.78 81.1 90.23 81.9 93.15 90.36 85.98 76.51 84.87 69.05 78.07 92.37 88 79.13 78.95 85.77 91.59 100 89.09 81.2 81.13 84 79.22 75.93 84.15 92.27 91.15 83.53 82.12 83.55 86.09 78.74 85 83.8 86.17 83.67 82.72 94.59 76.62 87.5 91.52 75.36 84.62 91.15 65.75 91.47 74.19 76.69 77.65 90.6 83.1 81.38 86.99 87.9 83.33 84.88 86.96 77.05 87.6 72.22 86.58 100 85.85 76.47 81.58 84.11 100 80.41 83.19 71.56 84.89 77.03 81.91 75.28 86.96 87.96 100 100 67.35 89.23 81.82 69.35 87.39 81.92 86.31 96.39 100 85.93 78.23 80.58 80.15 69.52 77.46 85.92 82.05 84.66 88.33 79.14 81.94 83.55 96.14 12.59 0.002468 0.045774 K cassette TNRC6A chr16 + chr16:24803139-24805864 chr16:24803139-24804793;chr16:24804971-24805864 chr16:24804794-24804970 NA 17.02 20 16.67 13.64 NA 8.33 18.18 7.89 68 31.58 NA 61.11 25 20 65 43.75 16.67 25.81 15.62 41.38 11.76 NA 30.3 59.09 NA 33.33 29.63 41.18 37.5 28.57 13.04 NA 23.81 25.81 56.52 34.48 13.89 16.67 64.1 23.08 22.73 37.93 18.92 5.26 45.24 17.39 48.94 38.46 31.67 31.25 33.33 30.77 16.67 21.74 24.24 13.33 25 35.71 26.32 28.89 15.56 11.11 21.88 41.67 24 20.41 24.24 31.03 45.76 25 25.71 42.86 34 18.75 36.67 26.09 27.78 34.69 18.18 26.09 28 35.14 25 25 26.32 27.27 32.14 39.39 28.21 45.83 33.33 30.77 36.36 25.81 25 23.33 24.44 30.77 33.33 18.75 27.66 32.14 21.43 24.32 56.25 33.33 28.33 22.22 30.77 34.15 28.57 28.57 NA 22.95 26.67 48.65 15.15 12.9 41.86 50 27.03 15.62 31.03 29.41 27.78 36 NA 7.89 20.83 32.43 25.93 31.58 44.44 37.5 17.39 20.83 25 12.2 27.78 19.05 43.48 8.33 44.44 16.67 30.77 16.67 33.33 NA NA NA 28.57 32 18.75 17.65 25.71 25.81 29.17 60.34 59.46 33.33 24 41.82 22.22 13.64 35 26.92 32.43 30 31.25 31.58 19.35 26.67 51.14 24.47 0.000932 0.022163 N cassette TPCN2 chr11 + chr11:68846489-68848867 chr11:68846489-68847301;chr11:68847352-68848867 chr11:68847302-68847351 41.38 83.33 63.16 NA 63.16 NA 61.54 NA 51.11 NA 100 NA 56.52 43.75 NA 33.33 54.84 63.16 73.85 100 80 100 100 78.69 100 100 100 71.88 57.78 68.42 62.3 100 NA 78 100 100 71.88 62.26 67.65 82.76 72.73 NA 69.35 66.67 64 33.33 76.67 65.38 70.59 63.33 62.16 100 64.1 NA 65.38 81.82 NA 72.41 57.89 75 63.33 47.22 77.78 51.28 65.96 46.88 71.43 69.7 65.38 77.55 60.61 62.5 51.61 73.33 60 61.54 66.67 55 54.05 82.76 51.52 59.38 76.19 100 43.48 57.69 35.71 45.95 58.33 100 100 100 100 100 62.86 73.68 NA 57.5 44.44 60.78 65.91 67.21 100 63.16 50 35.9 65.22 72.29 60.94 NA 51.72 36.59 40.62 54.17 31.43 38 43.75 71.43 100 71.15 40 55.26 73.44 64.29 62.5 60.47 71.43 52.63 77.42 50 75 100 NA 0 NA NA 100 56.25 100 NA 75 65 100 65.08 66.67 65.52 48 62.5 NA 100 NA NA 70.59 66.67 67.74 47.83 58.06 60.66 42.86 85 79.25 48.48 62.96 74.19 NA 61.11 70.59 54.76 62.07 72.73 52.38 69.23 65.08 92.5 27.42 0.001778 0.036195 N cassette TPD52L2 chr20 + chr20:62505170-62514071;chr20:62505170-62514102 chr20:62505170-62507168;chr20:62507229-62514071,chr20:62507229-62514102 chr20:62507169-62507228 100 71.3 64.37 42.11 85.29 56.52 54.48 73.13 69.04 81.69 81.1 100 77.63 82.03 70.48 78.46 52.17 78.26 72.65 82.89 79.2 81.73 76 68.22 83.54 69.41 67.07 76.12 75.68 80.92 55.65 79.37 100 73.17 77.54 60.66 71.91 79.55 70 47 81.25 74.29 87.04 85.39 74.79 70.31 76.32 70.83 77.92 77.11 69.43 65.22 69.49 66.04 51.05 70.64 75.76 82.68 78.08 78.38 65.15 65.15 83.75 62.5 73.27 68.89 72.73 69.23 80.85 59.57 68.97 57.14 73.91 70.59 75.47 82.98 65.79 69.33 79.63 81.16 77.27 74.14 65.98 77.85 72.22 78.05 63.04 76.27 65.94 83.12 71.25 50 73.81 80.95 69.23 81.63 60 62.04 69.84 71.19 81.08 75.86 76.76 74.75 60.49 68.18 67.96 67.15 72.36 53.7 66.22 61.4 49.09 84.31 75 67.33 68.09 48.99 61.54 74.6 57.45 72.88 59.3 62.91 74.67 62.75 67.62 78.26 80.3 71.43 80.62 79.31 79.03 100 86.67 91.79 79.55 67.35 73.68 70.33 69.35 83.72 60.71 71.61 80 73.43 64.86 74.14 81.48 79.05 100 77.24 73.97 63.33 72.22 73.13 72.13 71.91 71.08 54.81 74.29 82.67 64.65 63.53 45.35 72.62 79.69 69.64 73.33 78.38 55.26 77.38 73.17 57.19 -15.98 0.000402 0.013065 K cassette TRMU chr22 + chr22:46733842-46742318 chr22:46733842-46739158;chr22:46739266-46742318 chr22:46739159-46739265 100 100 44.44 42.31 100 71.43 60.61 100 60 100 100 NA 62.5 80 50 60 80 78.57 73.47 100 83.78 100 100 78.57 78.95 100 77.42 77.78 76.74 70.97 73.68 73.68 61.76 57.14 NA 51.85 75.61 68.52 100 60.61 100 100 73.53 100 100 100 76.67 77.27 66.67 63.89 76.32 52 64.52 100 51.72 80.65 100 74.19 76.47 69.57 70.97 63.83 100 55.17 68.29 83.72 75.68 78.12 100 62.75 78.57 70.97 68 68.75 63.83 72.73 61.11 67.74 75 64.29 82.76 82.76 82.93 73.08 78.57 100 100 82 81.25 72.31 60.87 52.38 100 100 82.05 100 65.22 55 84 65.45 66.04 75.56 87.5 64.29 51.11 57.58 100 78.05 78.57 100 68.18 76.74 61.19 NA 64.1 67.5 70.83 52.5 59.26 78.76 51.61 70.45 78.38 72.31 71.05 54.05 85.29 100 79.41 67.86 82.76 100 100 100 100 100 100 100 65.38 NA 63.33 55.56 100 74.29 84.21 100 68 100 NA 100 NA 100 68.18 64.81 70.97 63.33 100 69.39 65.91 50 68.57 67.65 67.35 73.91 54.55 79.17 69.7 73.33 86.84 83.87 71.43 100 76.39 52.19 -24.2 0.000257 0.009825 K alternative_last_exon TSGA14 chr7 - chr7:130066601-130067795;chr7:130056808-130067795 chr7:130061849-130067795 chr7:130056760-130056807 chr7:130058875-130061848 NA 43.75 34.29 38.1 33.33 NA NA 20 30 50 26.67 NA NA 41.67 27.27 NA 41.67 43.75 30.43 NA 30 NA 26.32 37.5 NA NA 25 25 50 NA NA 29.17 NA 33.33 20 18.18 46.67 32.5 30 15.38 NA 30.77 25 40 36.36 25 45.45 NA 32.35 21.74 22.58 20 36.84 28.57 41.18 NA NA 30 25 31.82 31.25 20 16.67 NA 30 45.45 35.29 25 29.73 25 40 16.67 23.08 21.43 33.33 40 35.29 23.53 62.5 26.67 28.57 30 NA 33.33 31.25 100 18.75 23.08 26 30.77 NA 21.05 33.33 35 29.41 NA 46.15 45 28.57 NA 39.29 15 30.77 27.78 NA NA 27.27 34.78 23.08 NA 26.67 23.08 60 47.37 25 NA 31.58 40 42.31 19.05 NA 27.5 46.15 46.15 29.17 NA NA 62.5 40 46.67 31.58 NA 22.73 40 NA 36.36 29.17 NA 41.67 NA 52.38 27.78 30.77 22.22 22.58 40 40 40 63.64 NA NA NA 28 71.43 25 NA 50 NA 27.78 20 35.29 28.57 27.78 27.78 26.67 NA 28 30 26.83 NA 37.5 33.33 30.77 20 -10.77 0.00032 0.032352 K cassette TSGA14 chr7 - chr7:130038881-130040547 chr7:130038881-130039879;chr7:130040096-130040547 chr7:130039880-130040095 100 100 100 100 74.29 100 NA 100 NA 100 86.11 NA NA NA 83.33 100 NA 87.5 100 NA NA NA 100 100 100 NA 100 100 100 NA NA 100 100 100 NA 70.83 82.14 87.5 88.37 75 NA 100 100 100 100 72 100 100 88.89 100 100 72 100 100 100 NA 100 100 100 83.72 100 100 100 100 73.17 100 100 80 89.09 76.67 100 NA 100 100 100 100 100 70 100 80.65 100 NA 100 100 77.27 100 100 100 100 70.27 100 100 100 100 100 NA NA 100 NA 100 100 100 70 100 100 NA 80 77.78 100 100 100 100 100 100 100 100 100 64.29 100 100 100 82.26 100 100 82.61 NA 100 100 100 100 100 100 80 100 NA 100 100 100 100 NA 100 100 100 74.67 100 100 100 100 NA 100 100 NA 68.57 100 85.11 NA 100 65 100 83.33 70.97 100 80 82.5 100 NA 100 100 89.86 100 79.17 78.72 100 75.84 -24.16 0.000755 0.018829 N cassette TTC28-AS1 chr22 + chr22:28315534-28331138 chr22:28315534-28318005;chr22:28318167-28331138 chr22:28318006-28318166 100 100 77.78 100 100 100 100 100 100 100 100 100 100 100 100 34.21 100 100 100 NA 100 100 100 100 NA 100 100 100 100 70.59 62.07 100 100 100 100 66.67 100 100 70 54.55 NA 100 55 80.77 100 60 100 78.12 100 73.91 100 76.19 100 77.78 100 100 100 84.85 100 71.43 77.78 100 69.57 100 100 100 100 67.74 100 100 100 59.26 65.38 62.5 100 100 100 100 65 100 NA 61.11 100 100 100 100 100 100 100 100 100 71.43 100 100 100 100 100 100 100 57.58 100 100 100 100 100 100 100 77.78 100 100 100 100 100 75.76 61.9 72 41.67 NA 100 100 62.96 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 66.67 100 79.17 NA 100 100 NA 100 100 82.05 100 100 100 100 59.09 70.97 42.31 73.08 100 64 NA 100 61.54 100 72.22 100 NA 100 NA 100 69.05 -30.95 0.000387 0.01306 N alternative_acceptor TUG1 chr22 + chr22:31368159-31368909 chr22:31368159-31368840 chr22:31368841-31368909 chr22:31368909-31368910 100 100 89.47 82.19 87.5 100 100 66.67 93.81 100 100 NA 100 100 100 89.91 91.74 78.87 92.11 100 100 100 100 80.25 83.87 100 100 77.94 100 100 100 88.31 100 100 100 74.32 83.08 84.38 87.72 84.85 86.05 93.55 92.75 100 100 93.9 100 93.58 100 100 100 78.33 100 77.65 86.15 100 70.49 100 100 100 90.24 82.76 92.11 87.95 88.28 87.69 88.33 80.21 87.67 90.83 90.48 94.83 91.97 95.76 84.4 100 88.51 92.54 95.15 85.15 100 100 100 74.51 91.07 100 100 100 86.92 89.04 100 74.19 100 100 87.5 100 88.61 92 100 100 83.33 100 100 87.01 91.13 95.24 100 100 84.68 100 90.36 88.89 93.69 100 96.18 89.92 100 100 100 87.97 84.21 90.6 94.83 88.32 89.42 100 90.24 87.76 100 100 100 100 100 100 100 100 87.04 80.3 68.97 100 100 100 100 92.31 100 83.33 100 94.05 100 100 100 100 86.44 100 79.17 100 91.89 83.95 93.02 83.5 100 100 93.55 100 90.57 82.35 91.95 91.55 93.15 100 88 88.52 94.99 80.91 -14.08 0.000754 0.034104 K coord_cassette UBAC2 chr13 + chr13:99890809-99966350 chr13:99890809-99896168;chr13:99896206-99896768;chr13:99896879-99966350 chr13:99896169-99896205;chr13:99896769-99896878 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92.96 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 88.24 100 100 100 83.33 100 100 100 100 100 100 100 100 100 100 100 90 100 100 93.75 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92.31 100 92.75 100 100 100 100 100 100 100 100 100 100 96.09 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 89.42 95.71 100 100 100 100 100 86.15 100 95.54 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 89.19 94.38 100 100 100 100 100 100 100 100 100 100 100 100 89.59 -10.41 0 0 K cassette UBAP2 chr9 - chr9:33998863-34017047 chr9:33998863-34011624;chr9:34011663-34017047 chr9:34011625-34011662 0 0 0 0 0 0 NA 0 4.88 0 0 NA 8 0 0 0 6.67 7.81 0 0 4 0 0 4.26 0 0 20 0 12.82 0 6.38 6 0 0 0 0 0 1.49 0 8.62 0 0 0 0 0 7.14 0 7.69 0 3.85 0 34.48 2.56 0 0 0 0 9.62 0 0 0 11.11 10.53 4.88 11.76 0 7.14 8.93 6.06 13.43 0 0 10.2 0 0 0 0 11.11 0 0 0 9.52 0 0 15.79 0 0 14.58 0 0 0 20.83 0 0 0 NA 17.39 0 1.64 0 0 4.88 0 0 6.82 0 0 0 0 0 0 0 4.44 0 0 4.88 0 0 0 4.76 4.48 9.52 0 3.33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NA 0 0 0 0 0 9.68 0 0 0 0 0 NA 0 7.14 19.05 0 0 2.5 0 22.22 0 0 0 0 0 5.26 0 0 7.69 9.3 7.69 0 0 17.13 17.13 0.000163 0.007046 K cassette UBE2V1 chr20 - chr20:48700792-48729643;chr20:48700792-48732021 chr20:48700792-48713208;chr20:48713358-48729643,chr20:48713358-48732021 chr20:48713209-48713357 100 85.45 89.17 90.97 88.89 76.32 100 89.71 92 94.59 90.07 100 86.67 92.97 100 89.47 100 90.3 89.72 84.85 86.73 83.76 86.52 92.62 89.72 79.81 85.34 92.42 83.84 83.17 85.82 92.81 100 88.07 94.17 87.5 85.71 92.51 93.28 75.15 100 93.48 87.85 100 89.39 87.84 80.77 87.8 93.75 89.23 79.28 76.15 74.19 100 74.49 89.08 84.91 88.89 100 91.18 95.73 88.33 94.74 91.89 89.81 86.27 84.51 90.1 90.68 83.08 88.65 87.77 85.39 100 90.58 88.76 94.78 92.72 100 96.02 100 91.18 100 88.46 100 78.41 93.85 93.65 96.05 89.94 87.9 78.95 100 91.74 90.12 91.22 81.1 100 100 94.48 93.89 100 92.76 94.17 95.73 94.44 95.12 91.52 100 85.61 84.68 92.8 92.41 85.71 90.79 92.52 80.17 85.96 100 92.54 94.44 100 86.16 100 100 97.18 87.5 80.56 92.47 88.52 89.86 100 90.45 90.07 91.33 89.01 85.61 91 92.5 100 86.67 90.78 100 94.74 90.51 90.97 100 90.48 86.93 100 89.86 91.85 100 93.75 91.21 92.86 100 85.07 86.62 75.93 100 100 100 86.96 86.67 100 89.62 87.01 89.52 85.94 91.94 91.67 91.18 77.55 -13.63 0.000251 0.009668 N cassette UBXN11 chr1 - chr1:26624554-26633082 chr1:26624554-26628184;chr1:26628214-26633082 chr1:26628185-26628213 NA 53.26 43.75 NA 46.67 NA 69.12 NA 64.81 NA 66 100 59.46 53.7 NA NA 53.33 NA 60 NA 72.13 100 65.96 55.81 52.94 62.79 54.55 65.52 65.56 76.34 67.74 44.44 27.78 NA 100 13.04 55.56 66.67 63.64 18.6 62.86 NA 68.24 72.22 44.44 NA 53.33 46.67 65.22 61.11 100 48.84 64.71 42.11 57.69 63.27 NA 70.83 65 66.67 68 NA 79.37 60 69.39 100 58.97 61.54 61.22 26.67 63.1 52.63 64.1 55 58.45 69.23 65.52 46.67 59.09 60.47 54.55 100 50.77 75 57.89 NA 48.98 48 75.86 63.83 48.89 43.9 59.09 57.89 51.02 69.57 36.36 45.21 56.52 67.11 68.85 77.38 76.19 64.52 43.33 50 71.43 48.15 73.78 50 60 42.86 36.36 NA NA 60.47 73.08 46.67 100 76.09 45.16 60.42 57.14 54.55 46.88 50.5 60.61 NA 84.31 NA 45.45 NA 100 NA 63.33 100 52.17 51.22 44.44 79.41 NA 59.26 100 62.96 NA 66.23 NA 68.75 NA 77.27 100 61.4 71.79 62.07 NA 50.98 100 55 56.25 45.61 55.56 NA 75 NA 53.33 75.76 100 45.16 59.26 NA 48.28 NA 61.31 35.28 -26.03 0.000231 0.009149 K alternative_last_exon UCHL5 chr1 - chr1:192985526-192990226;chr1:192987951-192990226 chr1:192989512-192990226,chr1:192989587-192990226 chr1:192984900-192985525;chr1:192987536-192987950 chr1:192989437-192989511 0 3.26 11.72 15.69 6.52 9.3 16.67 16.26 13.33 13.33 10.31 4.35 6.38 10.29 12.3 12.24 15.71 5.56 11.11 0 1.92 9.86 4.55 12.05 10.64 2.22 8.54 15.38 2.04 17.31 7.69 5.8 2.86 2.56 3.33 18.75 12.5 11.49 2.33 20.45 6.45 8.11 5.66 12.06 1.67 15.79 4.55 14.39 2.56 11.29 18.18 25.93 10.53 21.17 11.11 7.35 8.89 15.79 8 20 9.86 6.25 12.77 1.82 12.05 14.63 4.26 13.64 10.84 17.78 6.9 9.38 5.75 8.45 11.11 10.67 5.26 10.45 5.66 11.43 5.56 9.38 4.55 8.47 7.58 8.57 4.6 8.82 8.64 12.03 27.78 37.8 9.76 7.23 9.84 13.95 4.17 12.24 5.26 6.45 14.07 13.24 9.52 2.44 24.32 10.45 10.53 6.9 6.35 3.51 2 22.37 10.34 0 15.08 9.59 13.64 16.76 1.32 5.19 14.29 13.54 8.75 5.97 7.5 7.32 6 12.82 25.24 8.7 12.73 7.69 12.5 5.13 11.67 10 3.23 11.63 14.29 5.26 14.81 6 3.06 14.63 16.8 6.67 27.27 15.79 25.93 1.3 2.06 7.55 12.66 17.33 18.6 19.44 12.68 5.88 8.33 21.54 4.55 8.7 7.41 14.04 12 16.07 4.11 3.45 4.23 4.35 7.32 16.36 9.38 20.99 11.61 0.000121 0.021773 N cassette UNC84B chr22 - chr22:39148671-39151767 chr22:39148671-39150646;chr22:39150712-39151767 chr22:39150647-39150711 54.76 60.47 54.55 42.86 55.26 40.48 27.67 46.67 47.88 61.11 57.14 30.43 39.08 52.24 44.44 51.97 33.65 42.11 48.13 53.7 43.59 42.11 52.53 46.51 47.62 61.6 29.09 42.08 51.4 47.96 33.04 41.67 51.56 45.45 47.87 68 33.71 44.44 49.49 63.16 44.26 16.67 46.25 44.68 53.95 34.33 42.57 29.85 44.44 37.9 44.24 54.24 36.46 34.78 37.65 43.71 30 35.16 49.33 42.67 47.37 50 47.67 40 39.57 36.11 62.5 41.18 54.03 62.42 45.05 52.78 48.82 34.54 56.44 47.54 49.56 42.36 34.25 37.5 44.44 39.29 41.88 42.86 51.06 25 38.02 44.21 50.93 51.64 47.46 71.15 46.15 57.89 42.05 58.33 68.97 33.96 31.13 38.78 57.66 47.59 45.07 42.24 29.08 44.04 46.67 41.92 53.55 54.84 43.51 37.89 36.07 39.47 35.48 41.16 53.09 55.26 51.04 48.22 43.27 42.74 45.28 45.21 40 32.47 49.19 57.14 48.98 32.2 55.77 50 62 32.26 53.85 42.96 50.91 53.85 46.67 68.33 50 30.61 36.59 42.12 63.01 49.66 41.38 55.56 37.21 60.47 55.56 52.38 32.26 37.04 35.43 33.72 32.86 36.78 32.58 58.49 48.03 50.5 46.53 43.57 34.31 51.92 34.18 36.02 40 39.25 30.91 41.78 44.44 62.79 18.35 0.000142 0.006409 K cassette UPF3B chrX - chrX:118972491-118975038 chrX:118972491-118974608;chrX:118974648-118975038 chrX:118974609-118974647 0 0 0 0 0 0 0 0 0 0 0 NA 0 0 0 0 0 0.91 0 0 0 0 0 0 0 0 0 0 0 0 11.76 4.41 0 0 0 15.15 0 0 2.86 33.33 0 3.17 0 0 0 0 2.99 8.06 0 0 0 3.64 14.29 2.88 0 0 7.32 0 0 5.41 0 0 0 0 0 0 0 0 0 21.21 0 0 0 0 0 0 0 0 3.92 0 4.35 14 4.65 0 0 0 7.37 0 0 0 0 0 0 0 2.94 0 14.93 0 0 0 0 0 0 8.99 6.17 5.17 3.41 0 0 0 7.14 0 0 0 0 4.88 11.86 0 0 0 0 7.78 0 5.88 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 9.73 0 0 10.17 0 0 0 0 0 0 0 0 0 0 34.29 11.63 3.08 0 4.08 0 0 2 0 4.29 10.11 0 0 2.22 0 13.39 13.39 0.000075 0.003971 K cassette USP25 chr21 + chr21:17214860-17236586 chr21:17214860-17222095;chr21:17222192-17236586 chr21:17222096-17222191 17.65 3.9 10.34 3.7 2.3 0 6.02 5.45 11.58 0 4 NA 2.5 7.5 2.44 0 6.06 1.92 9.09 0 11.29 3.23 7.89 13.04 0 0 2.44 4.84 10.42 14.04 9.84 9.62 NA 2.56 2.67 15 4.55 9.26 10.71 23.08 9.52 NA 7.14 2.7 1.92 4.88 3.77 11.36 5.41 3.03 4.76 17.65 5.56 3.75 3.23 7.27 10 5.71 8.7 8.11 8.33 8.33 6.78 2.22 4.26 4.35 5.71 2.94 4.26 19.23 13.33 3.57 9.26 10.91 13.56 11.11 15.15 10.87 1.92 10.53 9.52 16.28 7.14 8.51 9.21 0 11.36 10.61 7.81 5.88 18.75 25.4 5.26 8.33 3.95 10.96 2.53 5 7.89 4.17 6.12 4.48 15.38 9.09 4.23 1.69 3.28 6.85 3.7 2.7 3.7 4.92 1.64 4.17 12.75 6.67 5.77 18.29 5.77 8.51 2.38 3.39 0 5 1.85 3.03 8.33 10.42 14.52 4.69 7.55 7.69 5.88 4.35 6.78 5.56 17.39 12.73 2 6.82 3.85 2.5 8.16 2.56 8.33 7.69 8.33 5 18.75 2.56 NA 1.96 6.25 3.23 0 5 4 2.94 2.08 23.73 4.26 7.14 2.38 3.7 2.22 4.35 6.06 15.38 6.06 8.33 8 8 5.71 21.16 15.45 0.000054 0.003066 K alternative_acceptor USP33 chr1 - chr1:78187587-78187708 chr1:78187611-78187708 chr1:78187587-78187610 chr1:78187586-78187587 NA 100 50.88 46 66.67 100 59.52 36.07 48.72 68 76.09 NA 62.5 67.92 44.83 51.35 78.79 56.1 69.7 0 58.14 100 67.92 52.78 100 44.44 54.84 55 51.92 56.41 68.29 55.56 100 37.14 60.53 100 63.27 59.52 52 100 58.33 53.85 54.29 77.27 100 64.29 55 58.18 45.45 66.67 60.47 83.87 100 62.16 60 80 73.68 67.74 47.22 60.87 68.18 72.41 73.81 59.46 54.55 69.57 57.5 72.22 55.1 100 60 55.26 48 66.67 53.19 65.22 75 50 63.41 45.24 53.57 60.53 71.11 54.17 56 30.56 100 47.62 62.86 73.53 100 100 50 56.41 62 64.1 51.28 68.09 53.45 100 60.56 71.67 63.64 69.23 80.49 57.58 62.75 58.62 68.18 NA 100 55.56 59.02 NA 73.47 70.37 66.67 58.24 100 68.85 68.18 63.83 68.75 59.52 60.32 55 59.09 53.66 55.56 68.75 100 100 48.94 56.76 57.5 54.84 62.79 55.17 57.69 50 100 53.19 NA 76.92 70.97 60 52.17 72.41 NA 0 NA 100 58.46 63.33 59.09 71.43 66.67 47.06 71.74 100 62.16 52.94 64.29 50 56.41 65.22 61.7 58.7 56.76 55.56 58.06 62.86 60.47 100 39.53 0.000262 0.018316 K cassette USP8 chr15 + chr15:50774263-50781997 chr15:50774263-50776471;chr15:50776559-50781997 chr15:50776472-50776558 70.97 48.39 56.96 60 57.63 100 36.36 61.54 43.24 60 59.65 NA 47.92 52.73 100 100 41.07 48.98 58.33 36.84 54.79 54.84 49.15 41.94 52.08 53.45 44.71 63.83 52.63 41.67 43.66 65.85 55.56 36.11 57.61 69.44 59.02 54.39 45.98 59.26 41.67 52.63 47.83 56.36 100 46.15 42.55 53.52 57.45 70 52 68.42 75 57.63 46.94 46.15 63.27 48.15 69.23 44.44 46.81 54 52.78 47.37 56.45 60 55.56 50 43.01 80 38.03 41.07 55.56 47.73 41.67 48.39 54.41 48.98 51.22 64.15 59.38 53.85 49.18 62.5 44.44 71.05 50 35.42 62.07 59.38 48.84 68.09 34.55 46.97 46.58 53.85 63.64 52.54 47.17 45.83 52.17 56 62.96 64.58 74.14 55.56 50 52.86 50 70.97 52.94 55.07 46.67 45.45 35.44 28.57 52.31 41.67 45 54.79 48.28 46.48 52.87 50 74.51 39.53 44.64 57.58 44.79 100 67.8 71.79 54.55 52.63 62.07 55.74 61.73 69.57 61.29 47.17 73.33 62.9 64.44 39.13 63.83 59.49 38.89 60 NA 72.31 NA 62.16 58.7 68 53.7 43.64 66.67 50 50 81.63 48.98 64.86 41.86 52 57.14 70.97 53.73 40.91 49.23 44.44 59.26 43.9 52.91 68.93 16.03 0.001306 0.028484 N cassette UTRN chr6 + chr6:145142155-145148746 chr6:145142155-145148483;chr6:145148523-145148746 chr6:145148484-145148522 18.75 7.14 10.74 39.71 27.08 NA NA 8.82 18.82 20.59 12.33 0 40.7 5.13 28.95 9.26 21.33 23.85 10.94 0 8.82 18.18 9.57 35.71 8.33 16.13 0 13.89 18.24 18.46 15.85 13.33 12.96 55.17 7.55 23.64 13.33 11.28 21.43 26.09 26.19 10.53 5.8 13.73 0 10 10.34 22.64 11.96 7.14 15.79 62.96 15.62 27.08 22.73 17.31 23.53 30.23 11.11 13.73 7.69 23.81 40.79 23.08 18.29 20 14.04 27.08 19.12 26.42 21.74 21.59 8.33 25.71 26.32 2.94 20.73 35.94 14.89 8.33 NA 20.45 7.62 29.79 11.11 6.67 8.11 21.88 25.53 15.94 0 25.29 10.71 15.38 8.16 14.96 31.67 0 27.59 18.6 14.55 5.19 0 27.27 41.3 21.5 18.75 20.55 21.13 21.59 8.62 20 16.07 0 21.43 22.22 8.93 27.27 6.67 10.64 26.67 20.34 16.95 30.59 14.71 11.11 10.29 14.93 17.19 13.97 0 28.57 6.45 10.87 11.29 0 24.53 16.18 9.62 21.18 4.17 3.54 11.43 13.73 30.23 17.06 20 8.22 NA 10.64 NA 24.06 14.49 18.42 46.67 21.05 16.67 13.04 20.65 31.17 25.86 20.59 17.81 5.56 41.07 0 29.73 24.39 13.79 22.22 23.33 28.57 16.16 26.26 10.1 0.002526 0.046509 N alternative_acceptor VAMP4 chr1 - chr1:171679955-171688310 chr1:171686389-171688310 chr1:171679955-171686388 chr1:171679954-171679955 NA 13.46 9.43 27.91 23.53 10 NA 7.14 10.91 15.62 12 NA 23.08 17.07 17.24 22 20.45 8.7 16.67 5.56 16.67 38.46 16.67 12.5 5.88 13.33 15 10.34 10 15 16.22 11.11 NA 11.11 12.2 38.1 14.63 13.16 11.11 84.88 23.53 20 9.52 11.11 11.11 15.79 7.14 17.39 10.53 14.29 7.69 31.58 13.04 15.38 14.63 13.04 15.38 10.91 11.36 16.67 25.71 20.59 18.52 17.24 17.02 12 22.22 16.67 11.11 34.04 16.67 14 16.67 25.93 11.36 11.43 21.31 13.04 15.56 14.29 22.22 24 23.08 11.11 23.91 30.77 14.81 15.38 17.5 11.11 40 27.78 18.42 15.15 25 18.75 33.33 12.5 11.76 27.27 8.51 10.84 2.78 11.11 22.73 23.81 11.11 20.37 8.57 35.29 8.2 15.56 19.74 19.05 7.02 18.18 11.11 21.54 12.5 14.93 25.42 19.64 22.22 15.38 15.62 9.09 16.67 41.67 15.62 21.57 6.82 15.79 11.43 19.35 23.81 17.65 10.64 17.86 25 17.5 18.75 21.43 NA 18.52 13.04 7.25 22.22 10.34 6.82 21.43 NA 9.09 21.88 15.38 11.76 31.25 18.6 21.43 18.07 32.89 14.89 9.68 10 9.09 11.11 10 8.51 19.51 11.11 19.35 13.64 11.76 15.38 33.47 18.09 0.000087 0.007199 K cassette VRK3 chr19 - chr19:50511084-50519280 chr19:50511084-50512492;chr19:50512643-50519280 chr19:50512493-50512642 82.22 85.71 75.68 54.84 82.14 74.51 87.93 92.31 100 100 85.53 100 88.89 81.43 100 100 100 100 100 100 81.4 100 65.31 92.78 84.27 100 90.8 87.72 92.94 94.32 89.86 80 86.25 87.59 95.28 72.97 89.29 93.27 89.06 81.67 71.67 75.47 93.33 100 100 91.84 88.64 91.21 86.32 93.75 100 75.34 76 76.54 88.14 87.14 70.59 85.06 92.31 80.56 84.88 83.33 88.89 86.67 86.11 89.39 100 90.48 88.89 87.91 91.46 100 83.58 88.37 88.31 85.48 78.46 84.29 91.18 93.81 81.36 87.5 82.67 81.08 91.8 100 100 100 90.14 100 100 67.27 81.43 78.72 87.06 60.47 89.55 76.34 92.63 93.24 100 92.04 92.09 100 100 89.55 100 100 95.45 79.75 94.68 89.29 84.21 80.61 92.13 100 100 92.11 100 100 90.43 83.51 86.72 92.86 87.64 92.96 73.08 100 90.72 75.76 93.46 88.3 89.62 92.65 100 85.61 100 100 90 100 83.53 94.44 100 93.7 77.78 86.96 100 100 82.28 79.82 67 92.93 100 91.4 63.08 84.62 100 100 100 73.24 89.33 100 92 83.33 73.58 87.84 90 90.28 85.15 84.78 88 88.33 89.86 74.29 -15.57 0.001677 0.034541 K cassette WAC chr10 + chr10:28879762-28897114 chr10:28879762-28884661;chr10:28884971-28897114 chr10:28884662-28884970 86.46 92.2 92.68 94.32 89.67 92.91 97.7 92.94 89.58 89.92 89.57 100 93.67 89.14 91.01 89.62 92.03 94.81 89.42 90.95 82.1 78.34 87.5 88.89 89.11 92.78 84.95 90.15 85.57 87.88 89.84 92.93 100 83.78 90.81 85.54 90.62 88.87 90.45 77.37 87.3 94.79 85.09 86.57 89.95 87.14 85.44 86.07 92.9 89.68 87.64 75 88.69 88.85 91.34 87 95.91 92.79 82.87 89.41 85.95 91 91.44 92.38 86.82 87.19 86.87 87.87 93.3 81.4 90.2 85.86 91.48 91.62 85.71 90.76 89.91 87.94 86.91 91.76 89.5 92.77 88.04 86.39 90.13 93.38 95.74 92.13 92.61 90.09 87.11 76.63 92.05 90.85 89.57 92.13 87.94 80.87 88.79 92.38 89.87 89.06 85.87 91.07 93.91 89.67 89.11 88.46 88.51 96.54 89.34 91.6 95.29 100 86.35 93.79 81.97 89.83 92.4 94.14 92.23 92.14 89.29 91.03 89.32 90.06 90.97 94.17 88.89 92.38 79.63 90.56 86.4 96.02 80.57 82.79 88.68 92.34 91.92 88.6 89.42 88.15 92.63 89.8 87.11 86.19 85.57 90.1 89.63 84.04 100 92.56 87.14 88.24 88.24 89.84 87.93 88.05 90.19 76.14 87.22 89.76 92.18 86.7 96.07 81.86 88.89 90.89 90.43 92.88 93.63 89.81 89.81 77 -12.81 0.000063 0.003482 N cassette WAPAL chr10 - chr10:88232102-88233634 chr10:88232102-88232368;chr10:88232522-88233634 chr10:88232369-88232521 100 83.64 79.7 82.67 79.8 100 100 65.82 63.55 69.33 83.5 100 100 76.74 61.17 70.79 74.51 80.65 80.9 71.43 71.59 100 76.15 78.67 82.05 59.65 70.89 78.21 73.53 78.57 71.13 84.15 100 62.86 74.36 60.42 73.33 82.56 81.91 73.96 100 84.75 100 76.53 100 72.45 68.63 84.75 77.53 100 81.03 67.65 67.35 79.82 64.94 100 100 83.75 91.03 67.52 86.84 100 85.26 79.65 82.61 84.91 77.01 64.84 86 66.98 79.38 81.03 72.5 92.16 76.77 78 78.05 79.13 89.04 66.2 77.19 78.31 76.39 100 77.1 100 100 84.31 78.76 79.49 81.25 77.46 86.15 77.78 79.49 85.51 89.11 74.29 79.49 100 100 73.83 100 100 87.5 82.14 76.24 100 79.49 100 79.1 84.38 100 100 80.87 77.6 72.73 89.61 78.87 77.53 100 100 82.83 83.52 86.29 84.31 69.84 100 73.24 85.71 72.73 100 72.09 83.13 100 67.74 67.74 100 85.59 100 84.62 69.33 100 73.68 68.57 77.27 100 75.95 100 100 100 100 75.64 80.95 80.3 82.93 100 68.06 84.25 67.65 81.08 100 67.33 79.75 85.29 88.64 100 83.75 83.17 78.81 75.86 73.33 81.03 67.65 -13.38 0.001523 0.032072 N alternative_acceptor WDR27 chr6 - chr6:170070790-170072350 chr6:170071054-170072350 chr6:170070790-170071053 chr6:170070789-170070790 NA NA 56.1 50 100 NA NA 23.53 50 39.47 37.5 100 54.55 38.46 25.93 56.52 55.88 48.48 59.57 NA 33.33 NA 41.38 46.15 38.46 NA NA 30 35 53.33 50 52.94 100 13.04 NA 100 68 29.41 25 100 NA 66.67 NA 33.33 31.25 40.91 NA 29.63 46.88 60 34.29 73.08 60 51.43 28.57 38.89 NA 31.25 47.06 34.62 46.67 52.94 53.85 44.83 50 40 47.37 54.55 33.33 55.88 66.67 42.11 43.75 40 37.5 41.67 52.94 NA 52.5 35.71 100 48.48 42.86 16.67 41.94 NA 17.39 26.92 47.06 32.5 NA 100 64 66.67 28.57 NA 28.57 52.83 50 41.67 63.33 42.86 17.24 40 64.15 33.33 31.11 40 30 NA 27.27 56 44.44 NA 44.44 44.83 52.94 44.83 58.82 30.56 35.42 69.23 30 50 54.29 21.05 18.18 58.82 37.84 NA 36 45.95 NA 100 33.33 NA 50 50 45.16 NA 60.87 39.39 NA 50 35.48 NA 30 56 NA NA NA NA 35.42 63.64 34.29 43.48 52 56.25 45.45 70.27 50 40.62 30.43 45.83 45.45 18.18 38.64 40.43 46.67 66.67 50 NA 44.44 86.54 42.1 0.000223 0.016117 K alternative_acceptor WDR6 chr3 + chr3:49044965-49049067 chr3:49044965-49048853 chr3:49048854-49049067 chr3:49049067-49049068 65.79 55.56 67.86 51.02 57.58 68 87.91 100 25 39.39 57.58 NA 56.82 60 36 44 49.33 54.1 47.62 34.78 50 66.67 67.86 38.71 57.61 33.33 50 56.1 45.71 45.65 49.18 50 65.85 48.54 66.67 80 69.86 36.13 46.67 73.53 72.92 46.67 44.29 55.77 69.23 46 50 42.86 57.75 44.19 65.52 78.08 60.61 59.09 48.05 42.7 55.88 42.86 38.6 53.76 38.16 58.23 58.06 61.9 44.44 66.67 40.52 55.56 53.33 70.34 38.24 28.21 50.45 34.19 58.49 39.44 54.39 51.79 48.39 34.29 70.18 33.68 67.27 62.86 42.65 69.77 23.53 35.48 36.84 36.14 42.86 86.11 36.54 100 45.33 65 74.36 53.49 31.33 36.36 44.74 32.14 35.82 44.19 50 32.84 36.72 27.66 41.56 66.67 33.33 57 44.35 52.5 32.56 29.57 59.46 45.65 73.68 32.22 35.19 34.12 45.68 37.1 56.16 30.51 61.36 62.07 39.42 71.05 44.44 50 37.04 53.19 32.43 44.44 54.17 66.67 73.17 58.82 61.67 45.71 52.63 28.98 60 56.52 23.64 50 21.05 69.57 100 100 37.76 48.39 74.29 65.31 36.9 57.78 45.26 77.61 56.9 43.59 42.42 57.69 64.79 58.54 44.29 52.33 58.18 69.62 53.12 56.6 50 77.84 27.84 0.000138 0.010653 N alternative_acceptor WDR77 chr1 - chr1:111984012-111984646 chr1:111984227-111984646 chr1:111984012-111984226 chr1:111984011-111984012 32.61 21.57 33.91 39.22 31.88 30 45.45 31.67 18.75 25 19.05 16.13 29.17 32.31 7.29 42.11 32.65 31.25 26.13 1.89 27.59 13.73 27.5 35.05 27.85 16.05 24.53 26.97 36.11 35.37 25.64 26.56 26.42 43.59 25 39.47 37.11 29.66 37.86 43.75 53.85 23.08 30 32.39 28.57 11.65 29.55 29.03 39.74 40.74 19 46.61 50 30.88 27.27 28.99 36 27.63 34.65 27.72 39.81 44.83 40.28 27.12 41.03 42 38.2 24.72 28.57 48.6 33.64 26.25 37.63 34.82 40.57 34.38 51.02 32.67 39.45 21.24 36.51 40.43 32.39 37.88 28.33 24.14 26.39 31.91 30.3 19.18 18.03 46.81 22.22 20 25 36.84 31.88 30.19 31.19 21.57 26.24 33.62 25.25 28.05 36.63 18.8 27.01 24.62 28.06 14.61 27.97 25.29 39.13 9.88 18.95 29.41 22.78 25.14 30.59 39.33 22.22 32.14 29.89 39.51 35.48 18.25 28.81 55.56 24.78 33.33 15.79 14.86 11.27 28.57 14.58 7.14 39.02 52.94 26.05 47.37 25 30.67 35.71 35.16 34.83 29.25 42.86 20.41 23.44 11.84 7.23 23.61 31.48 31.58 49.18 40.38 38.75 60.29 33.33 43.82 29.07 24.24 25.86 35 45.16 28.93 24.17 41.56 30.97 36.67 40.85 46.67 29.66 45.22 15.56 0.000444 0.025668 N cassette WHSC1 chr4 + chr4:1936990-1941380 chr4:1936990-1940177;chr4:1940260-1941380 chr4:1940178-1940259 100 100 85.71 100 100 100 100 100 79.07 100 100 NA 100 76.27 100 100 90.28 100 100 100 86.44 100 100 100 100 100 100 88.79 100 100 92.31 100 100 100 100 100 100 100 91.76 92.41 85 95.15 100 100 100 100 100 100 100 85.71 100 86.11 100 100 100 100 100 90.77 100 100 92.86 85.94 100 94.12 100 100 100 100 90.28 82.05 100 92.31 100 100 81.82 90.14 80.95 94.38 100 92.68 100 100 100 100 93.88 100 100 100 91.96 96.05 100 89.33 100 100 100 100 100 91.46 100 100 100 91.3 100 100 100 90.41 95.83 100 92.77 100 100 91.94 100 100 100 100 93.75 100 100 100 100 89.66 93.27 89.86 100 100 100 100 100 100 90.72 100 100 100 100 100 100 100 100 100 100 100 100 100 100 84.44 100 100 100 100 100 100 92.94 100 100 100 100 100 94 90.48 100 100 100 100 94.12 100 94.74 93.67 94.49 100 100 92.75 100 89.91 -10.09 0.000449 0.01397 K alternative_acceptor WHSC1 chr4 + chr4:1957577-1957813 chr4:1957577-1957709 chr4:1957710-1957813 chr4:1957813-1957814 100 100 100 88.57 100 100 78.26 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 82 100 100 90.2 78.43 100 100 100 100 100 93.07 100 100 100 100 100 72.55 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 79.37 100 100 100 100 100 91.55 100 100 91.8 100 100 100 100 100 100 100 100 100 100 100 87.69 100 100 100 100 100 100 100 100 100 90.79 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 92.65 100 100 100 NA 100 100 100 100 80 91.23 94.05 100 100 100 100 100 100 100 100 87.5 100 100 100 100 100 100 100 100 80.69 -19.31 0.000001 0.000094 N coord_cassette YEATS4 chr12 + chr12:69756688-69764485 chr12:69756688-69759412;chr12:69759480-69759569;chr12:69759665-69764485 chr12:69759413-69759479;chr12:69759570-69759664 100 83.82 100 100 100 100 100 100 81.48 100 100 100 100 100 100 100 100 87.5 100 100 100 100 100 91.89 100 100 100 100 91.8 100 100 100 100 100 100 69.77 89.61 100 93.06 79.41 100 100 100 100 100 77.97 100 91.67 100 100 100 91.8 100 100 100 100 100 91.67 100 100 100 100 100 85.96 90 89.29 100 100 100 91.07 88.24 100 100 90.77 100 100 100 90.43 100 100 100 100 82.35 100 100 100 100 100 100 88.75 100 79.52 100 100 100 100 100 89.02 100 100 100 100 100 100 92.21 91.07 100 100 100 100 100 100 100 100 100 100 87.69 100 100 100 84.21 100 100 100 80 82.05 100 100 100 100 100 100 100 100 100 100 83.82 100 100 100 100 100 100 100 84.88 100 100 100 100 100 100 100 100 100 100 100 100 100 100 85.71 100 100 100 100 100 100 90 100 100 100 100 100 100 82.61 -17.39 0 0.000015 N alternative_acceptor ZBTB44 chr11 - chr11:130108452-130109706;chr11:130108503-130109706 chr11:130108449-130109706 chr11:130108449-130108451;chr11:130108452-130108502 chr11:130108448-130108449;chr11:130108451-130108452 NA 13.75 11.46 16.47 20.59 0 21.05 0 24.29 26.92 16 NA 16.39 0 0 21.93 28.09 17.28 18.75 0 20.34 0 0 20.56 24.76 0 0 15.98 11.63 19.15 16.67 20.55 0 0 18.52 29.51 0 18.39 25.49 30.43 27.78 11.59 18.37 7.69 0 21.84 0 13.92 16.18 28.12 17.07 22.22 17.95 7.04 21.88 0 0 20.99 17.28 14.29 20.51 25.42 0 18.6 15.66 0 21.98 16.88 18.75 20.78 11.9 15.75 11.11 14.41 23.64 13.79 23.46 15.05 17.33 28.32 13.51 0 0 0 13.51 0 0 14.81 20.54 18.75 0 37.78 14.81 0 10.71 0 19.4 0 16.67 18.18 21.15 18.6 34.04 0 15.17 21.55 24.62 13.18 16.25 11.11 0 21.43 14.41 0 21.79 15.93 10.2 14.95 0 15.79 18 20.25 12.86 17.31 18.42 15.15 24.32 21.43 8.93 13.04 0 0 17.33 9.09 0 25 17.78 0 15.25 0 0 15.56 0 15.79 17.02 23.08 14.89 12 0 0 0 0 9.52 19.7 19.23 0 15.96 0 18.75 23.68 14.29 30.95 18.42 12.77 20.97 0 19.3 29.36 20 7.69 8.77 29.55 15.17 26.59 11.42 0.000289 0.019795 N alternative_acceptor ZFAND2A chr7 - chr7:1192768-1195088 chr7:1192878-1195088 chr7:1192768-1192877 chr7:1192767-1192768 100 100 NA 100 100 100 74.11 100 100 100 100 100 NA 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 65.85 82.14 100 NA 100 NA 100 100 76.19 100 100 100 73.91 100 NA 100 100 100 100 100 100 100 100 100 70.37 100 100 100 100 100 100 NA 100 NA 100 77.14 NA 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 100 75.86 100 100 100 73.53 100 NA 100 100 78.95 100 100 100 NA NA 100 NA 100 100 100 NA 83.33 100 100 100 NA NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NA 100 100 100 100 100 100 NA 83.78 100 100 NA 100 100 100 100 100 100 NA 100 NA NA 100 100 NA 100 72.73 100 100 100 NA 100 100 100 100 100 NA 82.05 100 100 100 100 100 100 100 100 70.59 100 100 100 100 100 100 88.09 -11.91 0.00091 0.03934 K alternative_acceptor ZMIZ2 chr7 + chr7:44796139-44796641 chr7:44796139-44796545 chr7:44796546-44796641 chr7:44796641-44796642 100 84.21 100 100 100 100 81.82 100 81.48 100 100 100 100 100 100 86.96 80 76.92 81.08 100 83.72 100 100 82.81 84.48 100 100 89.09 100 90 80 100 100 78.7 100 60.98 87.5 91.14 87.8 71.43 100 100 84.38 100 100 100 100 83.02 100 86.96 100 74.07 77.05 66.67 88.64 87.34 100 86.54 75.47 100 100 100 100 100 89.04 83.33 100 83.67 84.31 82.69 100 100 89.39 83.33 88.73 100 84.62 89.36 84 77.27 75.93 80.49 100 81.63 83.33 100 100 88.89 84.91 83.65 100 75 71.43 100 80 100 NA 79.37 86 100 80.26 89.74 90.48 85 70.59 100 87.32 83.33 88.89 100 81.91 100 87.1 100 81.82 88.31 100 100 100 85.07 100 83.33 89.74 100 100 88.75 85.29 100 91.43 75 80.77 100 100 100 100 100 100 100 100 100 100 100 100 85 100 84.44 100 72.34 75 100 NA 100 79.59 100 86.27 79.41 100 88 90.2 57.14 87.3 88.52 100 81.48 83.67 77.42 100 79.17 91.07 100 82.93 86.21 90.48 72.75 -17.73 0.000065 0.005711 K cassette ZMYM2 chr13 + chr13:20534167-20567202 chr13:20534167-20544164;chr13:20544212-20567202 chr13:20544165-20544211 NA 20.41 35.44 21.79 20.93 22.22 56.82 39.22 17.74 31.58 26.32 NA 26.09 21.43 27.03 18.02 36.05 33.33 27.85 0 26.53 0 11.76 33.33 35 0 0 43.59 40.43 20 21.95 28.57 27.78 15.38 38.64 11.43 23.53 18.28 24.62 9.43 23.53 20.99 23.44 34 34.21 22.86 0 14.61 18 22.22 11.36 17.5 26.09 32.08 28.57 35.9 31.37 28.3 25.68 19.35 28.33 27.96 32.86 20.29 30.49 28.57 16.09 14.67 29.51 20.63 25 20.31 24.71 20.48 14.29 26.92 27.08 28.57 23.38 26.67 22.37 14 24.49 29.79 25.51 12.5 0 20.37 29.07 20 30.91 8.82 16.95 38.18 28.21 28.21 28.57 25.68 22.43 20.97 14.06 30.61 23.53 27.59 34.44 23.61 25 25.27 32.79 56.52 16.39 31.91 33.66 26.47 22.54 24.44 19.35 13.79 15.38 30.91 26.26 26.58 25.68 23.91 23.73 12.77 28.12 36.36 22.67 32.14 27.91 18.64 13.89 26.23 39.47 0 10 20 13.04 24.14 46.88 19.51 37.84 12.5 28.95 28.38 25 23.44 20.51 NA NA 24.14 24.69 31.37 18.48 19.72 28.4 23.29 22.99 14.08 25 21.67 18.75 33.9 25.71 33.33 19.74 20 21.33 18.46 28.38 27.87 24.71 12.75 -11.96 0.00178 0.036195 K cassette ZMYND11 chr10 + chr10:255989-282777 chr10:255989-267134;chr10:267297-282777 chr10:267135-267296 100 78.33 87.04 62.96 100 58.82 NA 72.34 67.92 74.32 85.71 100 81.63 81.58 86.84 81.82 75 76.92 78.22 100 85.96 24 77.61 82.26 100 42.59 69.84 100 70 80 83.87 82.69 100 85.11 75.47 63.16 80.7 79.35 100 63.04 65 NA 78.38 89.47 100 88.89 76.92 77.32 86.36 77.94 73.55 72.73 71.05 79.76 68.29 80 68 72.13 81.36 72.73 70.77 60 74.19 100 83.7 79.41 80.56 78.87 83.33 68.6 68.89 65.38 80.61 78.67 72.73 78.05 61.9 72.46 85.48 77.78 75.61 67.65 80 74.07 85.82 100 58.33 76.27 81.37 76.19 100 70.18 80.7 100 79.41 70.37 69.44 77.03 84.85 100 77.94 65.82 71.43 86.05 81.33 89.61 84.27 77.68 69.81 100 89.55 83.05 67.5 100 87.5 80.21 80 80.58 100 85.23 76.39 76.79 77.55 67.95 84.09 76.36 80.77 84.85 80 73.02 71.74 66 100 83.08 63.89 100 75.68 53.33 64 NA 73.08 100 100 78.05 80.39 74.29 60.47 76.67 100 100 NA 61.11 75.71 72.92 72.13 79.49 90.16 80.43 67.33 60.32 81.4 100 84.93 82.76 61.02 80 80.6 84.13 81.63 86.89 100 79.25 79.76 65.88 -13.88 0.001974 0.039151 K cassette ZNF618 chr9 + chr9:116795009-116798579 chr9:116795009-116797470;chr9:116797516-116798579 chr9:116797471-116797515 NA 0 11.11 0 0 NA 13.04 0 0 0 0 NA 0 NA 0 NA 8.33 0 0 0 NA NA 0 17.39 28 NA 0 13.33 0 NA 0 0 NA NA NA 10 0 13.89 7.69 13.64 20 NA 0 5.56 NA 0 27.27 11.54 13.33 0 0 24.14 0 22.22 11.11 22.73 NA NA 0 10 11.76 NA NA 15.15 14.29 16.67 11.76 11.11 0 12.5 0 4.44 0 0 0 9.09 0 13.79 0 0 NA 0 0 0 NA NA 0 0 7.55 5.71 NA 12 0 0 0 NA 31.25 11.43 0 20.69 0 22.22 3.12 0 8 4.76 12.82 0 0 NA NA 0 12.5 0 0 12.9 0 11.76 0 0 0 0 20 5 0 0 NA 0 0 0 0 0 0 0 NA 0 0 5.56 0 NA 0 NA 0 8.33 NA 12.5 0 6.9 NA NA NA NA 0 NA 0 NA 23.53 0 4.76 17.5 NA 8.33 0 0 12.9 NA 0 0 0 5.88 0 15.79 0 13.07 13.07 0.001479 0.031411 K cassette ZNF692 chr1 - chr1:249150146-249150712 chr1:249150146-249150571;chr1:249150622-249150712 chr1:249150572-249150621 chr1:249149924-249150145;chr1:249150713-249150761 100 100 100 100 100 100 82.98 100 100 100 55 NA 100 100 100 100 81.58 100 100 100 100 100 NA 100 100 100 100 100 100 100 79.41 100 100 84 100 68.75 88.64 87.23 73.68 76.92 50 100 100 100 100 100 100 84.09 100 100 75.86 80.7 100 100 100 100 NA 79.55 81.25 77.27 100 85.71 NA 100 100 89.58 100 100 100 100 85.71 100 86.79 100 100 100 100 68.75 80.77 100 74.07 100 100 65.22 100 100 100 100 100 81.13 100 NA 100 NA 79.63 NA NA 100 100 88.74 100 89.13 81.16 100 87.5 100 92.19 100 100 NA 100 100 100 100 89.8 84.09 100 88.41 100 100 100 100 76.6 86.11 100 86.3 100 NA 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 93.06 100 100 100 100 100 100 100 NA 100 77.46 78.26 80.65 100 100 100 72.41 100 100 100 100 100 100 100 100 100 100 100 100 100 76.92 -23.08 0.001166 0.026172 K cassette ZNF75A chr16 + chr16:3362769-3366911 chr16:3362769-3363048;chr16:3363176-3366911 chr16:3363049-3363175 NA 100 100 NA 100 NA NA NA 83.87 100 100 NA 100 100 NA 100 100 100 59.09 NA 100 NA NA 100 60 NA NA 61.54 100 100 100 NA 100 100 NA 61.54 100 100 63.33 65.96 NA 100 100 79.17 100 NA NA 81.08 100 100 100 59.26 76.92 100 100 100 NA 87.5 80 100 100 100 NA 100 79.31 100 100 100 100 67.31 70 100 100 86.96 NA 83.87 100 64.71 71.43 100 NA 83.33 100 100 73.17 NA 100 75 68.18 80 NA NA NA 100 69.7 100 100 50 82.35 100 100 100 100 77.27 78.95 77.27 100 78.95 100 100 76.19 100 100 100 100 100 100 84.48 100 100 100 83.33 100 82.35 82.35 78.57 100 100 100 59.26 100 NA 100 64.52 NA 100 100 100 100 100 100 100 NA 100 100 100 NA 100 NA NA NA NA 100 100 NA 100 NA 100 75.76 80.77 78.12 100 100 60 NA 100 100 100 100 NA 76.19 64.29 100 65.96 -34.04 0.000276 0.010372 K cassette ZRANB2 chr1 - chr1:71530821-71532458 chr1:71530821-71531360;chr1:71531436-71532458 chr1:71531361-71531435 27.27 40.4 48.45 43.9 50.89 28.57 65.11 56.88 33.33 61.62 38.2 100 58.16 55.21 35.58 61.96 51.65 45.65 45.71 22.73 48.89 42.31 53.49 56.88 65 33.33 43.1 53.12 50.65 52 45.83 51.11 100 55.56 35.16 63.24 54.96 43.01 45.26 68.67 48.48 33.33 63.04 46.9 40 37.5 52.24 55.56 44 57.61 32.06 73.74 52.7 40.96 46.05 58.93 44.59 57.14 54.12 55.43 58.1 59.14 54.55 38.95 50 59.13 73.48 60.92 57.29 65.12 61.17 45.78 54.26 58.76 52.13 50 64.29 50 59.02 55.03 50 51.61 47.27 64.29 48.67 31.25 65.82 42 42.95 44.86 56 55.56 67.02 48.1 61.11 49.06 34.57 52.71 50.79 58.49 58.49 49.39 43.06 42.86 55.7 47.85 50.89 68.31 55.65 36.67 46.08 54.37 34.73 44.68 45.27 41.25 41.67 55.24 52.1 52.54 50.45 56.16 47.93 56.02 48.04 54.26 35.29 60.61 63.33 40.56 39.42 25.22 40.74 45.38 56.1 46.55 46.43 61.4 60.71 26.79 55.32 58.65 37.14 50.7 62.6 51.47 44.32 46.15 52.17 25 35.71 36.67 57.92 41.24 45.71 50.56 61.62 58.44 63.36 71.28 62.03 46.15 48.72 57.81 39.45 50 59.62 51.76 47.32 53.52 35.53 43.75 50.56 66.9 16.34 0.000443 0.013931