Gene Set Class Comparison Results

Description of the problem:

Number of classes: 2
Column of the Experiment Descriptors sheet that defines class variable: OBNSC vs heNSC
Number of genes that passed filtering criteria: 18037
Type of Gene Sets: Gene Ontology
Number of total investigated Gene Sets: 3875
Type of univariate test used: Two-sample T-test
Random variance model was not used because distribution assumptions of this model were not satisfied.

Tests used to find significant gene sets are: LS/KS permutation test, Efron-Tibshirani's GSA maxmean test
The threshold of determining significant gene sets is 0.005
LS/KS permutation test finds gene sets which have more genes differentially expressed among the phenotype classes than expected by chance.
Efron-Tibshirani's test uses 'maxmean' statistics to identify gene sets differentially expressed.

Summary of Results:

325 out of 3875 investigated gene sets passed the 0.005 significance threshold
LS/KS permutation test found 125 significant gene sets.
Efron-Tibshirani's maxmean test found 240 significant gene sets (under 200 permutations).
By Gene Ontologies:
    41 out of the 307 investigated Cellular Component (CC) categories are significant.
    45 out of the 620 investigated Molecular Function (MF) categories are significant.
    239 out of the 2948 investigated Biological Process (BP) categories are significant.

Table - Table of Gene Sets: 325 gene sets sorted by LS permutation p-value (significant p-values are in red)
To access the list of genes within each gene set, click the hyperlinked number of genes for each gene set.

class 1:1, class 2:2


	GO category	GO ontology	GO term	Number of genes	Heatmap link	LS permutation p-value	KS permutation p-value	Efron-Tibshirani's GSA test p-value
1	GO:0051351	BP	positive regulation of ligase activity	90	heatmap	0.00001	0.00012	< 0.005 (+)
2	GO:0051443	BP	positive regulation of ubiquitin-protein ligase activity	88	heatmap	0.00001	0.00008	< 0.005 (+)
3	GO:0000502	CC	proteasome complex	82	heatmap	0.00001	0.0002	< 0.005 (+)
4	GO:0005746	CC	mitochondrial respiratory chain	64	heatmap	0.00001	0.00001	0.01 (+)
5	GO:0015934	CC	large ribosomal subunit	74	heatmap	0.00001	0.00001	< 0.005 (+)
6	GO:0015935	CC	small ribosomal subunit	73	heatmap	0.00001	0.00001	< 0.005 (+)
7	GO:0070469	CC	respiratory chain	67	heatmap	0.00001	0.00001	< 0.005 (+)
8	GO:0015078	MF	hydrogen ion transmembrane transporter activity	88	heatmap	0.00001	0.00001	< 0.005 (+)
9	GO:0051439	BP	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	86	heatmap	0.00001	0.00033	0.02 (+)
10	GO:0045737	BP	positive regulation of cyclin-dependent protein kinase activity	14	heatmap	0.00002	0.00188	0.02 (+)
11	GO:0016469	CC	proton-transporting two-sector ATPase complex	56	heatmap	0.00003	0.00003	0.025 (+)
12	GO:0051436	BP	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	81	heatmap	0.00004	0.00048	0.02 (+)
13	GO:0046930	CC	pore complex	84	heatmap	0.00005	0.00003	0.25 (+)
14	GO:0031145	BP	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	81	heatmap	0.00005	0.00116	0.02 (+)
15	GO:0006220	BP	pyrimidine nucleotide metabolic process	37	heatmap	0.00008	0.01686	0.095 (+)
16	GO:0016679	MF	oxidoreductase activity, acting on diphenols and related substances as donors	8	heatmap	0.00008	0.00311	< 0.005 (+)
17	GO:0016681	MF	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	8	heatmap	0.00008	0.00311	< 0.005 (+)
18	GO:0045275	CC	respiratory chain complex III	6	heatmap	0.00008	0.0001	< 0.005 (+)
19	GO:0022904	BP	respiratory electron transport chain	63	heatmap	0.00011	0.00027	< 0.005 (+)
20	GO:0033178	CC	proton-transporting two-sector ATPase complex, catalytic domain	21	heatmap	0.00014	0.00481	< 0.005 (+)
21	GO:0005643	CC	nuclear pore	75	heatmap	0.00015	0.00006	0.285 (+)
22	GO:0006413	BP	translational initiation	66	heatmap	0.00015	0.0001	0.06 (+)
23	GO:0015985	BP	energy coupled proton transport, down electrochemical gradient	49	heatmap	0.0002	0.00016	0.025 (+)
24	GO:0015986	BP	ATP synthesis coupled proton transport	49	heatmap	0.0002	0.00016	0.025 (+)
25	GO:0045259	CC	proton-transporting ATP synthase complex	33	heatmap	0.00021	0.00069	0.04 (+)
26	GO:0015992	BP	proton transport	67	heatmap	0.00029	0.0001	0.025 (+)
27	GO:0042773	BP	ATP synthesis coupled electron transport	52	heatmap	0.00029	0.00008	0.025 (+)
28	GO:0042775	BP	mitochondrial ATP synthesis coupled electron transport	52	heatmap	0.00029	0.00008	0.025 (+)
29	GO:0000377	BP	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	95	heatmap	0.00029	0.01897	0.11 (+)
30	GO:0000398	BP	nuclear mRNA splicing, via spliceosome	95	heatmap	0.00029	0.01897	0.11 (+)
31	GO:0016126	BP	sterol biosynthetic process	48	heatmap	0.00033	0.01875	< 0.005 (+)
32	GO:0051352	BP	negative regulation of ligase activity	87	heatmap	0.00033	0.00242	0.02 (+)
33	GO:0051444	BP	negative regulation of ubiquitin-protein ligase activity	87	heatmap	0.00033	0.00242	0.02 (+)
34	GO:0016655	MF	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	45	heatmap	0.00038	0.00029	0.01 (+)
35	GO:0019829	MF	cation-transporting ATPase activity	41	heatmap	0.00044	0.00089	< 0.005 (+)
36	GO:0030964	CC	NADH dehydrogenase complex	38	heatmap	0.00044	0.00008	0.01 (+)
37	GO:0045271	CC	respiratory chain complex I	38	heatmap	0.00044	0.00008	0.01 (+)
38	GO:0022618	BP	ribonucleoprotein complex assembly	72	heatmap	0.00044	0.01429	0.075 (+)
39	GO:0008173	MF	RNA methyltransferase activity	18	heatmap	0.00046	0.00427	0.105 (+)
40	GO:0000079	BP	regulation of cyclin-dependent protein kinase activity	66	heatmap	0.0005	0.00467	0.115 (+)
41	GO:0009219	BP	pyrimidine deoxyribonucleotide metabolic process	11	heatmap	0.00055	0.16801	< 0.005 (+)
42	GO:0006446	BP	regulation of translational initiation	47	heatmap	0.00058	0.00176	0.035 (+)
43	GO:0016651	MF	oxidoreductase activity, acting on NADH or NADPH	73	heatmap	0.00066	0.00269	< 0.005 (+)
44	GO:0007032	BP	endosome organization	18	heatmap	0.00067	0.01644	0.175 (+)
45	GO:0005753	CC	mitochondrial proton-transporting ATP synthase complex	28	heatmap	0.00068	0.00115	0.04 (+)
46	GO:0015002	MF	heme-copper terminal oxidase activity	19	heatmap	0.00072	0.01173	< 0.005 (+)
47	GO:0016675	MF	oxidoreductase activity, acting on heme group of donors	19	heatmap	0.00072	0.01173	< 0.005 (+)
48	GO:0016676	MF	oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	19	heatmap	0.00072	0.01173	< 0.005 (+)
49	GO:0031397	BP	negative regulation of protein ubiquitination	100	heatmap	0.00073	0.00484	0.02 (+)
50	GO:0005732	CC	small nucleolar ribonucleoprotein complex	22	heatmap	0.00073	0.0013	0.075 (+)
51	GO:0005775	CC	vacuolar lumen	6	heatmap	0.00078	0.00087	< 0.005 (+)
52	GO:0006839	BP	mitochondrial transport	84	heatmap	0.00085	0.001	< 0.005 (+)
53	GO:0016090	BP	prenol metabolic process	7	heatmap	0.00088	0.0279	0.015 (+)
54	GO:0016093	BP	polyprenol metabolic process	7	heatmap	0.00088	0.0279	0.015 (+)
55	GO:0006733	BP	oxidoreduction coenzyme metabolic process	47	heatmap	0.00093	0.00545	0.07 (+)
56	GO:0006818	BP	hydrogen transport	70	heatmap	0.001	0.00035	0.025 (+)
57	GO:0016585	CC	chromatin remodeling complex	84	heatmap	0.00103	0.0058	0.17 (+)
58	GO:0006754	BP	ATP biosynthetic process	96	heatmap	0.00104	0.00007	0.025 (+)
59	GO:0000313	CC	organellar ribosome	36	heatmap	0.00104	0.00181	0.14 (+)
60	GO:0005761	CC	mitochondrial ribosome	36	heatmap	0.00104	0.00181	0.14 (+)
61	GO:0009120	BP	deoxyribonucleoside metabolic process	6	heatmap	0.00106	0.05484	0.02 (+)
62	GO:0003954	MF	NADH dehydrogenase activity	37	heatmap	0.00108	0.00011	0.035 (+)
63	GO:0050136	MF	NADH dehydrogenase (quinone) activity	37	heatmap	0.00108	0.00011	0.035 (+)
64	GO:0016407	MF	acetyltransferase activity	67	heatmap	0.00117	0.00643	0.09 (+)
65	GO:0043297	BP	apical junction assembly	5	heatmap	0.00129	0.00673	< 0.005 (+)
66	GO:0046496	BP	nicotinamide nucleotide metabolic process	34	heatmap	0.0013	0.00595	0.04 (+)
67	GO:0006626	BP	protein targeting to mitochondrion	35	heatmap	0.00144	0.00008	0.13 (+)
68	GO:0070585	BP	protein localization in mitochondrion	35	heatmap	0.00144	0.00008	0.13 (+)
69	GO:0005793	CC	ER-Golgi intermediate compartment	54	heatmap	0.00149	0.00207	0.15 (+)
70	GO:0015036	MF	disulfide oxidoreductase activity	20	heatmap	0.00153	0.01039	0.035 (+)
71	GO:0016860	MF	intramolecular oxidoreductase activity	36	heatmap	0.00157	0.01254	0.085 (+)
72	GO:0000123	CC	histone acetyltransferase complex	59	heatmap	0.00171	0.0164	0.055 (-)
73	GO:0034220	BP	ion transmembrane transport	89	heatmap	0.0018	0.00043	< 0.005 (+)
74	GO:0031902	CC	late endosome membrane	57	heatmap	0.0018	0.04378	0.19 (+)
75	GO:0022624	CC	proteasome accessory complex	17	heatmap	0.0018	0.01149	0.035 (+)
76	GO:0009451	BP	RNA modification	48	heatmap	0.00187	0.0019	0.145 (+)
77	GO:0010340	MF	carboxyl-O-methyltransferase activity	7	heatmap	0.00192	0.00614	0.06 (+)
78	GO:0051998	MF	protein carboxyl O-methyltransferase activity	7	heatmap	0.00192	0.00614	0.06 (+)
79	GO:0009060	BP	aerobic respiration	44	heatmap	0.00197	0.02884	0.205 (+)
80	GO:0008757	MF	S-adenosylmethionine-dependent methyltransferase activity	84	heatmap	0.00199	0.0064	0.155 (+)
81	GO:0005839	CC	proteasome core complex	24	heatmap	0.00222	0.00961	< 0.005 (+)
82	GO:0000307	CC	cyclin-dependent protein kinase holoenzyme complex	20	heatmap	0.00225	0.03801	< 0.005 (+)
83	GO:0042274	BP	ribosomal small subunit biogenesis	19	heatmap	0.00227	0.12176	0.005 (+)
84	GO:0010923	BP	negative regulation of phosphatase activity	9	heatmap	0.00227	0.02141	< 0.005 (-)
85	GO:0032515	BP	negative regulation of phosphoprotein phosphatase activity	9	heatmap	0.00227	0.02141	< 0.005 (-)
86	GO:0009262	BP	deoxyribonucleotide metabolic process	33	heatmap	0.0023	0.3103	0.05 (+)
87	GO:0016591	CC	DNA-directed RNA polymerase II, holoenzyme	75	heatmap	0.00259	0.00084	0.12 (+)
88	GO:0016667	MF	oxidoreductase activity, acting on sulfur group of donors	41	heatmap	0.0026	0.01797	0.035 (+)
89	GO:0000314	CC	organellar small ribosomal subunit	12	heatmap	0.00267	0.0215	0.125 (+)
90	GO:0019362	BP	pyridine nucleotide metabolic process	36	heatmap	0.00272	0.01139	0.04 (+)
91	GO:0006477	BP	protein amino acid sulfation	5	heatmap	0.00277	0.08207	0.085 (+)
92	GO:0070938	CC	contractile ring	5	heatmap	0.00297	0.01177	0.015 (+)
93	GO:0043666	BP	regulation of phosphoprotein phosphatase activity	17	heatmap	0.00305	0.03412	0.155 (+)
94	GO:0000118	CC	histone deacetylase complex	42	heatmap	0.00332	0.01537	0.07 (+)
95	GO:0051149	BP	positive regulation of muscle cell differentiation	16	heatmap	0.00342	0.00842	< 0.005 (-)
96	GO:0006275	BP	regulation of DNA replication	54	heatmap	0.00356	0.09182	0.09 (+)
97	GO:0042625	MF	ATPase activity, coupled to transmembrane movement of ions	68	heatmap	0.00382	0.00039	< 0.005 (+)
98	GO:0009086	BP	methionine biosynthetic process	9	heatmap	0.00417	0.03637	< 0.005 (-)
99	GO:0008080	MF	N-acetyltransferase activity	57	heatmap	0.00433	0.02722	0.26 (+)
100	GO:0009116	BP	nucleoside metabolic process	65	heatmap	0.00437	0.00565	0.16 (+)
101	GO:0016574	BP	histone ubiquitination	13	heatmap	0.00457	0.1326	0.01 (+)
102	GO:0006984	BP	ER-nucleus signaling pathway	34	heatmap	0.00462	0.15113	0.18 (+)
103	GO:0046356	BP	acetyl-CoA catabolic process	29	heatmap	0.00474	0.02293	0.22 (+)
104	GO:0045261	CC	proton-transporting ATP synthase complex, catalytic core F(1)	10	heatmap	0.00477	0.02584	0.025 (+)
105	GO:0008033	BP	tRNA processing	72	heatmap	0.00484	0.00132	0.165 (+)
106	GO:0006352	BP	transcription initiation	89	heatmap	0.00487	0.00134	0.085 (-)
107	GO:0048806	BP	genitalia development	17	heatmap	0.00518	0.06274	< 0.005 (-)
108	GO:0003729	MF	mRNA binding	72	heatmap	0.00584	0.00158	< 0.005 (-)
109	GO:0048144	BP	fibroblast proliferation	38	heatmap	0.00627	0.07128	< 0.005 (-)
110	GO:0048145	BP	regulation of fibroblast proliferation	38	heatmap	0.00627	0.07128	< 0.005 (-)
111	GO:0009067	BP	aspartate family amino acid biosynthetic process	17	heatmap	0.00657	0.02681	< 0.005 (-)
112	GO:0006555	BP	methionine metabolic process	13	heatmap	0.00746	0.00773	< 0.005 (-)
113	GO:0033176	CC	proton-transporting V-type ATPase complex	19	heatmap	0.00805	0.0038	< 0.005 (+)
114	GO:0019348	BP	dolichol metabolic process	5	heatmap	0.00866	0.0878	< 0.005 (-)
115	GO:0042026	BP	protein refolding	16	heatmap	0.00949	0.04918	< 0.005 (+)
116	GO:0016638	MF	oxidoreductase activity, acting on the CH-NH2 group of donors	8	heatmap	0.0095	0.04943	< 0.005 (+)
117	GO:0006694	BP	steroid biosynthetic process	83	heatmap	0.0098	0.02274	< 0.005 (+)
118	GO:0006695	BP	cholesterol biosynthetic process	35	heatmap	0.01014	0.06254	< 0.005 (+)
119	GO:0045445	BP	myoblast differentiation	26	heatmap	0.01091	0.01034	< 0.005 (-)
120	GO:0005838	CC	proteasome regulatory particle	13	heatmap	0.01153	0.00948	< 0.005 (+)
121	GO:0006611	BP	protein export from nucleus	26	heatmap	0.01187	0.00966	< 0.005 (+)
122	GO:0016251	MF	general RNA polymerase II transcription factor activity	48	heatmap	0.01436	0.00909	< 0.005 (-)
123	GO:0009066	BP	aspartate family amino acid metabolic process	23	heatmap	0.01625	0.0166	< 0.005 (-)
124	GO:0060323	BP	head morphogenesis	13	heatmap	0.01637	0.03273	< 0.005 (-)
125	GO:0043189	CC	H4/H2A histone acetyltransferase complex	24	heatmap	0.01656	0.06782	< 0.005 (+)
126	GO:0043516	BP	regulation of DNA damage response, signal transduction by p53 class mediator	14	heatmap	0.01729	0.01876	< 0.005 (+)
127	GO:0000380	BP	alternative nuclear mRNA splicing, via spliceosome	12	heatmap	0.01738	0.00067	0.515 (-)
128	GO:0032182	MF	small conjugating protein binding	39	heatmap	0.01908	0.00353	0.14 (+)
129	GO:0051427	MF	hormone receptor binding	96	heatmap	0.02009	0.0009	< 0.005 (-)
130	GO:0006999	BP	nuclear pore organization	8	heatmap	0.02164	0.00102	0.015 (-)
131	GO:0006596	BP	polyamine biosynthetic process	9	heatmap	0.02296	0.03714	< 0.005 (+)
132	GO:0031122	BP	cytoplasmic microtubule organization	7	heatmap	0.02351	0.12196	< 0.005 (+)
133	GO:0006734	BP	NADH metabolic process	8	heatmap	0.02456	0.26853	< 0.005 (-)
134	GO:0051147	BP	regulation of muscle cell differentiation	31	heatmap	0.02589	0.03316	< 0.005 (-)
135	GO:0048199	BP	vesicle targeting, to, from or within Golgi	14	heatmap	0.02633	0.00195	0.065 (+)
136	GO:0001836	BP	release of cytochrome c from mitochondria	32	heatmap	0.02636	0.17571	< 0.005 (-)
137	GO:0035140	BP	arm morphogenesis	5	heatmap	0.02788	0.07926	< 0.005 (-)
138	GO:0071680	BP	response to indole-3-methanol	9	heatmap	0.02792	0.28239	< 0.005 (-)
139	GO:0042303	BP	molting cycle	28	heatmap	0.02837	0.33948	< 0.005 (-)
140	GO:0042633	BP	hair cycle	28	heatmap	0.02837	0.33948	< 0.005 (-)
141	GO:0043030	BP	regulation of macrophage activation	9	heatmap	0.02869	0.00558	< 0.005 (+)
142	GO:0060343	BP	trabecula formation	11	heatmap	0.02927	0.06767	< 0.005 (-)
143	GO:0003727	MF	single-stranded RNA binding	35	heatmap	0.0303	0.0251	< 0.005 (-)
144	GO:0014009	BP	glial cell proliferation	5	heatmap	0.03205	0.07926	< 0.005 (-)
145	GO:0014010	BP	Schwann cell proliferation	5	heatmap	0.03205	0.07926	< 0.005 (-)
146	GO:0051153	BP	regulation of striated muscle cell differentiation	27	heatmap	0.03224	0.0424	< 0.005 (-)
147	GO:0019211	MF	phosphatase activator activity	5	heatmap	0.03295	0.10683	< 0.005 (+)
148	GO:0050919	BP	negative chemotaxis	12	heatmap	0.03349	0.40324	< 0.005 (-)
149	GO:0016820	MF	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	95	heatmap	0.03411	0.00237	< 0.005 (+)
150	GO:0031057	BP	negative regulation of histone modification	7	heatmap	0.03486	0.12501	< 0.005 (+)
151	GO:0051155	BP	positive regulation of striated muscle cell differentiation	7	heatmap	0.03592	0.12189	< 0.005 (-)
152	GO:0035257	MF	nuclear hormone receptor binding	87	heatmap	0.03629	0.00318	< 0.005 (-)
153	GO:0009948	BP	anterior/posterior axis specification	13	heatmap	0.03632	0.0659	< 0.005 (-)
154	GO:0008299	BP	isoprenoid biosynthetic process	20	heatmap	0.03695	0.45465	< 0.005 (+)
155	GO:0042987	BP	amyloid precursor protein catabolic process	17	heatmap	0.03724	0.25964	< 0.005 (-)
156	GO:0008637	BP	apoptotic mitochondrial changes	42	heatmap	0.03858	0.12791	< 0.005 (-)
157	GO:0043492	MF	ATPase activity, coupled to movement of substances	94	heatmap	0.03961	0.00302	< 0.005 (+)
158	GO:0046912	MF	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	7	heatmap	0.04017	0.12402	< 0.005 (+)
159	GO:0032512	BP	regulation of protein phosphatase type 2B activity	5	heatmap	0.04047	0.10254	< 0.005 (-)
160	GO:0061041	BP	regulation of wound healing	35	heatmap	0.04103	0.04459	< 0.005 (+)
161	GO:0042626	MF	ATPase activity, coupled to transmembrane movement of substances	93	heatmap	0.04143	0.00394	< 0.005 (+)
162	GO:0071780	BP	mitotic cell cycle G2/M transition checkpoint	5	heatmap	0.04196	0.07523	< 0.005 (-)
163	GO:0060431	BP	primary lung bud formation	5	heatmap	0.04562	0.39288	< 0.005 (-)
164	GO:0032351	BP	negative regulation of hormone metabolic process	5	heatmap	0.04716	0.05829	< 0.005 (+)
165	GO:0032353	BP	negative regulation of hormone biosynthetic process	5	heatmap	0.04716	0.05829	< 0.005 (+)
166	GO:0090032	BP	negative regulation of steroid hormone biosynthetic process	5	heatmap	0.04716	0.05829	< 0.005 (+)
167	GO:0051920	MF	peroxiredoxin activity	11	heatmap	0.04752	0.00199	0.05 (+)
168	GO:0007063	BP	regulation of sister chromatid cohesion	8	heatmap	0.04841	0.33079	< 0.005 (-)
169	GO:0046825	BP	regulation of protein export from nucleus	10	heatmap	0.0492	0.14884	< 0.005 (+)
170	GO:0005902	CC	microvillus	37	heatmap	0.0496	0.49412	< 0.005 (+)
171	GO:0035112	BP	genitalia morphogenesis	5	heatmap	0.05041	0.39288	< 0.005 (-)
172	GO:0031528	CC	microvillus membrane	13	heatmap	0.05061	0.21041	< 0.005 (+)
173	GO:0019843	MF	rRNA binding	31	heatmap	0.05073	0.08516	< 0.005 (+)
174	GO:0016717	MF	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	5	heatmap	0.05153	0.22061	< 0.005 (+)
175	GO:0006390	BP	transcription from mitochondrial promoter	7	heatmap	0.05208	0.29012	< 0.005 (-)
176	GO:0010894	BP	negative regulation of steroid biosynthetic process	9	heatmap	0.05267	0.00485	< 0.005 (+)
177	GO:0045939	BP	negative regulation of steroid metabolic process	9	heatmap	0.05267	0.00485	< 0.005 (+)
178	GO:0048742	BP	regulation of skeletal muscle fiber development	23	heatmap	0.05429	0.05616	< 0.005 (-)
179	GO:0033599	BP	regulation of mammary gland epithelial cell proliferation	9	heatmap	0.05573	0.04894	< 0.005 (-)
180	GO:0050818	BP	regulation of coagulation	35	heatmap	0.05778	0.09516	< 0.005 (+)
181	GO:0001942	BP	hair follicle development	27	heatmap	0.05835	0.39117	< 0.005 (-)
182	GO:0022404	BP	molting cycle process	27	heatmap	0.05835	0.39117	< 0.005 (-)
183	GO:0022405	BP	hair cycle process	27	heatmap	0.05835	0.39117	< 0.005 (-)
184	GO:0009452	BP	RNA capping	6	heatmap	0.05847	0.00224	0.14 (+)
185	GO:0003338	BP	metanephros morphogenesis	7	heatmap	0.05871	0.16515	< 0.005 (-)
186	GO:0030522	BP	intracellular receptor mediated signaling pathway	89	heatmap	0.05898	0.02294	< 0.005 (-)
187	GO:0045995	BP	regulation of embryonic development	22	heatmap	0.06043	0.10632	< 0.005 (-)
188	GO:0050435	BP	beta-amyloid metabolic process	11	heatmap	0.06102	0.25829	< 0.005 (-)
189	GO:0045661	BP	regulation of myoblast differentiation	12	heatmap	0.06132	0.0694	< 0.005 (-)
190	GO:0003401	BP	axis elongation	5	heatmap	0.06144	0.20707	< 0.005 (+)
191	GO:0060602	BP	branch elongation of an epithelium	5	heatmap	0.06144	0.20707	< 0.005 (+)
192	GO:0016579	BP	protein deubiquitination	44	heatmap	0.06171	0.03594	< 0.005 (-)
193	GO:0031576	BP	G2/M transition checkpoint	26	heatmap	0.06338	0.16811	< 0.005 (-)
194	GO:0048008	BP	platelet-derived growth factor receptor signaling pathway	24	heatmap	0.0659	0.04764	< 0.005 (-)
195	GO:0060438	BP	trachea development	5	heatmap	0.06888	0.39288	< 0.005 (-)
196	GO:0060439	BP	trachea morphogenesis	5	heatmap	0.06888	0.39288	< 0.005 (-)
197	GO:0035258	MF	steroid hormone receptor binding	55	heatmap	0.0692	0.01856	< 0.005 (-)
198	GO:0060993	BP	kidney morphogenesis	9	heatmap	0.07523	0.07879	< 0.005 (-)
199	GO:0051055	BP	negative regulation of lipid biosynthetic process	20	heatmap	0.07674	0.09659	< 0.005 (-)
200	GO:0030521	BP	androgen receptor signaling pathway	57	heatmap	0.07993	0.02488	< 0.005 (-)
201	GO:0060688	BP	regulation of morphogenesis of a branching structure	17	heatmap	0.08349	0.14779	< 0.005 (-)
202	GO:0016202	BP	regulation of striated muscle tissue development	40	heatmap	0.08828	0.03566	< 0.005 (-)
203	GO:0004457	MF	lactate dehydrogenase activity	5	heatmap	0.08832	0.66734	< 0.005 (+)
204	GO:0060479	BP	lung cell differentiation	8	heatmap	0.0899	0.30171	< 0.005 (-)
205	GO:0048641	BP	regulation of skeletal muscle tissue development	27	heatmap	0.09133	0.0424	< 0.005 (-)
206	GO:0048286	BP	lung alveolus development	21	heatmap	0.09221	0.23357	< 0.005 (-)
207	GO:0006613	BP	cotranslational protein targeting to membrane	16	heatmap	0.09559	0.00343	0.075 (+)
208	GO:0033180	CC	proton-transporting V-type ATPase, V1 domain	7	heatmap	0.09584	0.42313	< 0.005 (+)
209	GO:0010830	BP	regulation of myotube differentiation	6	heatmap	0.09707	0.1675	< 0.005 (-)
210	GO:0006612	BP	protein targeting to membrane	34	heatmap	0.09786	0.0022	0.115 (+)
211	GO:0070509	BP	calcium ion import	6	heatmap	0.09801	0.03804	< 0.005 (-)
212	GO:0070588	BP	calcium ion transmembrane transport	6	heatmap	0.09801	0.03804	< 0.005 (-)
213	GO:0090279	BP	regulation of calcium ion import	6	heatmap	0.09801	0.03804	< 0.005 (-)
214	GO:0030518	BP	steroid hormone receptor signaling pathway	76	heatmap	0.09954	0.02674	< 0.005 (-)
215	GO:0071363	BP	cellular response to growth factor stimulus	18	heatmap	0.10205	0.2217	< 0.005 (-)
216	GO:0015662	MF	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	48	heatmap	0.10304	0.00878	< 0.005 (+)
217	GO:0006720	BP	isoprenoid metabolic process	40	heatmap	0.1131	0.82238	< 0.005 (+)
218	GO:0001656	BP	metanephros development	27	heatmap	0.11395	0.14719	< 0.005 (-)
219	GO:0001706	BP	endoderm formation	5	heatmap	0.11527	0.39288	< 0.005 (-)
220	GO:0031229	CC	intrinsic to nuclear inner membrane	5	heatmap	0.11543	0.31224	< 0.005 (-)
221	GO:0010559	BP	regulation of glycoprotein biosynthetic process	16	heatmap	0.11629	0.22102	< 0.005 (-)
222	GO:0060571	BP	morphogenesis of an epithelial fold	11	heatmap	0.11659	0.2482	< 0.005 (-)
223	GO:0008203	BP	cholesterol metabolic process	79	heatmap	0.11835	0.21018	< 0.005 (+)
224	GO:0004869	MF	cysteine-type endopeptidase inhibitor activity	23	heatmap	0.11998	0.00496	0.06 (+)
225	GO:0048634	BP	regulation of muscle organ development	41	heatmap	0.12393	0.05916	< 0.005 (-)
226	GO:0032653	BP	regulation of interleukin-10 production	6	heatmap	0.12611	0.16442	< 0.005 (+)
227	GO:0060572	BP	morphogenesis of an epithelial bud	9	heatmap	0.12675	0.41436	< 0.005 (-)
228	GO:0014014	BP	negative regulation of gliogenesis	8	heatmap	0.12936	0.32699	< 0.005 (-)
229	GO:0004448	MF	isocitrate dehydrogenase activity	7	heatmap	0.13293	0.24204	< 0.005 (-)
230	GO:0090030	BP	regulation of steroid hormone biosynthetic process	6	heatmap	0.14344	0.18172	< 0.005 (+)
231	GO:0014902	BP	myotube differentiation	18	heatmap	0.14349	0.37104	< 0.005 (-)
232	GO:0043583	BP	ear development	56	heatmap	0.14454	0.04058	< 0.005 (-)
233	GO:0010543	BP	regulation of platelet activation	8	heatmap	0.14513	0.60795	< 0.005 (-)
234	GO:0006661	BP	phosphatidylinositol biosynthetic process	7	heatmap	0.15075	0.36525	< 0.005 (-)
235	GO:0010389	BP	regulation of G2/M transition of mitotic cell cycle	8	heatmap	0.1528	0.11854	< 0.005 (-)
236	GO:0072001	BP	renal system development	80	heatmap	0.15892	0.54831	< 0.005 (-)
237	GO:0014909	BP	smooth muscle cell migration	24	heatmap	0.16309	0.08807	< 0.005 (-)
238	GO:0021781	BP	glial cell fate commitment	8	heatmap	0.16756	0.12377	< 0.005 (-)
239	GO:0045601	BP	regulation of endothelial cell differentiation	6	heatmap	0.1699	0.1994	< 0.005 (-)
240	GO:0010457	BP	centriole-centriole cohesion	6	heatmap	0.17076	0.1994	< 0.005 (-)
241	GO:0014910	BP	regulation of smooth muscle cell migration	22	heatmap	0.17279	0.06571	< 0.005 (-)
242	GO:0007492	BP	endoderm development	16	heatmap	0.18332	0.22102	< 0.005 (-)
243	GO:0055002	BP	striated muscle cell development	68	heatmap	0.18826	0.45133	< 0.005 (-)
244	GO:0010829	BP	negative regulation of glucose transport	5	heatmap	0.19047	0.30565	< 0.005 (+)
245	GO:0001822	BP	kidney development	79	heatmap	0.19048	0.58133	< 0.005 (-)
246	GO:0010464	BP	regulation of mesenchymal cell proliferation	18	heatmap	0.19185	0.28565	< 0.005 (-)
247	GO:0034765	BP	regulation of ion transmembrane transport	35	heatmap	0.19195	0.09878	< 0.005 (-)
248	GO:0060684	BP	epithelial-mesenchymal cell signaling	5	heatmap	0.19273	0.53004	< 0.005 (-)
249	GO:0010463	BP	mesenchymal cell proliferation	20	heatmap	0.19568	0.20344	< 0.005 (-)
250	GO:0022409	BP	positive regulation of cell-cell adhesion	14	heatmap	0.19595	0.48582	< 0.005 (+)
251	GO:0042147	BP	retrograde transport, endosome to Golgi	12	heatmap	0.19667	0.41516	< 0.005 (-)
252	GO:0014704	CC	intercalated disc	13	heatmap	0.20422	0.21041	< 0.005 (-)
253	GO:0044291	CC	cell-cell contact zone	13	heatmap	0.20422	0.21041	< 0.005 (-)
254	GO:0014812	BP	muscle cell migration	26	heatmap	0.21023	0.11572	< 0.005 (-)
255	GO:0031572	BP	G2/M transition DNA damage checkpoint	23	heatmap	0.21118	0.29402	< 0.005 (-)
256	GO:0044453	CC	nuclear membrane part	6	heatmap	0.21523	0.45874	< 0.005 (-)
257	GO:0007440	BP	foregut morphogenesis	8	heatmap	0.21978	0.39178	< 0.005 (-)
258	GO:0001709	BP	cell fate determination	20	heatmap	0.22418	0.17748	< 0.005 (-)
259	GO:0031128	BP	developmental induction	17	heatmap	0.22749	0.14779	< 0.005 (-)
260	GO:0045168	BP	cell-cell signaling involved in cell fate commitment	17	heatmap	0.22749	0.14779	< 0.005 (-)
261	GO:2000027	BP	regulation of organ morphogenesis	40	heatmap	0.22982	0.30191	< 0.005 (-)
262	GO:0022829	MF	wide pore channel activity	11	heatmap	0.23239	0.31232	< 0.005 (+)
263	GO:0034661	BP	ncRNA catabolic process	5	heatmap	0.23396	0.16219	< 0.005 (-)
264	GO:0022011	BP	myelination in the peripheral nervous system	7	heatmap	0.24738	0.20028	< 0.005 (-)
265	GO:0032292	BP	ensheathment of axons in the peripheral nervous system	7	heatmap	0.24738	0.20028	< 0.005 (-)
266	GO:0060795	BP	cell fate commitment involved in the formation of primary germ layers	12	heatmap	0.24921	0.53354	< 0.005 (-)
267	GO:0051148	BP	negative regulation of muscle cell differentiation	11	heatmap	0.24931	0.30063	< 0.005 (-)
268	GO:0032613	BP	interleukin-10 production	7	heatmap	0.24968	0.41649	< 0.005 (+)
269	GO:0003156	BP	regulation of organ formation	15	heatmap	0.25035	0.23021	< 0.005 (-)
270	GO:0008212	BP	mineralocorticoid metabolic process	5	heatmap	0.25442	0.79107	< 0.005 (+)
271	GO:0032341	BP	aldosterone metabolic process	5	heatmap	0.25442	0.79107	< 0.005 (+)
272	GO:0032344	BP	regulation of aldosterone metabolic process	5	heatmap	0.25442	0.79107	< 0.005 (+)
273	GO:0010560	BP	positive regulation of glycoprotein biosynthetic process	7	heatmap	0.25582	0.48299	< 0.005 (-)
274	GO:0048593	BP	camera-type eye morphogenesis	44	heatmap	0.25724	0.1595	< 0.005 (-)
275	GO:0060428	BP	lung epithelium development	7	heatmap	0.26376	0.71674	< 0.005 (-)
276	GO:0021772	BP	olfactory bulb development	10	heatmap	0.26838	0.58231	< 0.005 (-)
277	GO:0070848	BP	response to growth factor stimulus	25	heatmap	0.27456	0.36138	< 0.005 (-)
278	GO:0048546	BP	digestive tract morphogenesis	16	heatmap	0.28675	0.42243	< 0.005 (-)
279	GO:0060445	BP	branching involved in salivary gland morphogenesis	13	heatmap	0.28897	0.78534	< 0.005 (-)
280	GO:0007431	BP	salivary gland development	17	heatmap	0.31598	0.63796	< 0.005 (-)
281	GO:0007435	BP	salivary gland morphogenesis	17	heatmap	0.31598	0.63796	< 0.005 (-)
282	GO:0051591	BP	response to cAMP	35	heatmap	0.31942	0.63716	< 0.005 (+)
283	GO:0060487	BP	lung epithelial cell differentiation	5	heatmap	0.32517	0.53004	< 0.005 (-)
284	GO:0071664	CC	catenin-TCF7L2 complex	6	heatmap	0.32573	0.58108	< 0.005 (-)
285	GO:0030324	BP	lung development	84	heatmap	0.3309	0.55397	< 0.005 (-)
286	GO:0060541	BP	respiratory system development	91	heatmap	0.33586	0.57742	< 0.005 (-)
287	GO:0060767	BP	epithelial cell proliferation involved in prostate gland development	8	heatmap	0.33871	0.39178	< 0.005 (-)
288	GO:0060441	BP	epithelial tube branching involved in lung morphogenesis	15	heatmap	0.34198	0.87856	< 0.005 (-)
289	GO:0048660	BP	regulation of smooth muscle cell proliferation	41	heatmap	0.34601	0.56779	< 0.005 (-)
290	GO:0010092	BP	specification of organ identity	11	heatmap	0.34904	0.63918	< 0.005 (-)
291	GO:0032330	BP	regulation of chondrocyte differentiation	11	heatmap	0.3501	0.63918	< 0.005 (-)
292	GO:0008210	BP	estrogen metabolic process	10	heatmap	0.35146	0.41755	< 0.005 (-)
293	GO:0021988	BP	olfactory lobe development	11	heatmap	0.35476	0.61265	< 0.005 (-)
294	GO:0033057	BP	reproductive behavior in a multicellular organism	6	heatmap	0.35715	0.23453	< 0.005 (-)
295	GO:0005313	MF	L-glutamate transmembrane transporter activity	7	heatmap	0.36692	0.74279	< 0.005 (+)
296	GO:0002065	BP	columnar/cuboidal epithelial cell differentiation	6	heatmap	0.37005	0.46469	< 0.005 (-)
297	GO:0001759	BP	induction of an organ	13	heatmap	0.37019	0.35675	< 0.005 (-)
298	GO:0051924	BP	regulation of calcium ion transport	58	heatmap	0.37115	0.15888	< 0.005 (-)
299	GO:0030323	BP	respiratory tube development	87	heatmap	0.38028	0.53857	< 0.005 (-)
300	GO:0050819	BP	negative regulation of coagulation	19	heatmap	0.40609	0.3386	< 0.005 (-)
301	GO:0015074	BP	DNA integration	14	heatmap	0.40974	0.00343	0.185 (+)
302	GO:0048659	BP	smooth muscle cell proliferation	42	heatmap	0.41361	0.64659	< 0.005 (-)
303	GO:0045670	BP	regulation of osteoclast differentiation	20	heatmap	0.43188	0.88755	< 0.005 (-)
304	GO:0009084	BP	glutamine family amino acid biosynthetic process	16	heatmap	0.43618	0.72201	< 0.005 (+)
305	GO:0030195	BP	negative regulation of blood coagulation	18	heatmap	0.43749	0.39532	< 0.005 (-)
306	GO:0034332	BP	adherens junction organization	10	heatmap	0.4823	0.45912	< 0.005 (-)
307	GO:0060768	BP	regulation of epithelial cell proliferation involved in prostate gland development	7	heatmap	0.48245	0.48299	< 0.005 (-)
308	GO:0030168	BP	platelet activation	25	heatmap	0.4838	0.66342	< 0.005 (-)
309	GO:0006656	BP	phosphatidylcholine biosynthetic process	10	heatmap	0.48971	0.63948	< 0.005 (-)
310	GO:0042762	BP	regulation of sulfur metabolic process	6	heatmap	0.49192	0.78499	< 0.005 (-)
311	GO:0051176	BP	positive regulation of sulfur metabolic process	6	heatmap	0.49192	0.78499	< 0.005 (-)
312	GO:0046890	BP	regulation of lipid biosynthetic process	44	heatmap	0.49301	0.34266	< 0.005 (-)
313	GO:0030316	BP	osteoclast differentiation	24	heatmap	0.51522	0.8574	< 0.005 (-)
314	GO:0016833	MF	oxo-acid-lyase activity	8	heatmap	0.52644	0.31491	< 0.005 (-)
315	GO:0060425	BP	lung morphogenesis	18	heatmap	0.55469	0.90111	< 0.005 (-)
316	GO:0048730	BP	epidermis morphogenesis	14	heatmap	0.57303	0.68874	< 0.005 (-)
317	GO:0035272	BP	exocrine system development	20	heatmap	0.60507	0.88143	< 0.005 (-)
318	GO:0001933	BP	negative regulation of protein amino acid phosphorylation	41	heatmap	0.69008	0.86242	< 0.005 (+)
319	GO:0045638	BP	negative regulation of myeloid cell differentiation	23	heatmap	0.74313	0.8285	< 0.005 (-)
320	GO:0019865	MF	immunoglobulin binding	12	heatmap	0.78423	0.89304	< 0.005 (-)
321	GO:0002762	BP	negative regulation of myeloid leukocyte differentiation	12	heatmap	0.79936	0.87454	< 0.005 (-)
322	GO:0014046	BP	dopamine secretion	8	heatmap	0.82474	0.83797	< 0.005 (-)
323	GO:0014059	BP	regulation of dopamine secretion	8	heatmap	0.82474	0.83797	< 0.005 (-)
324	GO:0050804	BP	regulation of synaptic transmission	100	heatmap	0.91574	0.85457	< 0.005 (-)
325	GO:0050654	BP	chondroitin sulfate proteoglycan metabolic process	14	heatmap	0.9278	0.79277	< 0.005 (-)

Links to the genes within gene sets:
Gene Sets 1 - 100 ... Gene Sets 101 - 200 ... Gene Sets 201 - 300 ... Gene Sets 301 - 325

Filtering parameters:

R version 2.12.0 (2010-10-15)
Name of the project file: Hany_Project.xls
Time of the analysis: Fri Sep 30 15:06:38 2011

BRB-ArrayTools Version: 4.2.0 - Beta_2 (June 2011)
Project annotated by SOURCE (source.stanford.edu), searched by gene identifier: Symbol, on 7/22/2011 3:40:29 PM

Spot Filters: OFF

Average the replicate spots within an array: OFF

Normalization:

Normalize (center) each array using quantile normalization.

Gene Filters: OFF

Gene Subsets:
INCLUDE ONLY genes in any of the following genelists:
(Analysis:present_plosonedata);
(Analysis:Presenti in tutti OBNSC)