Table S1. One Way ANCOVA - Affymetrix Array of Genes HIV vs HIV/MDD "© 2000-2009 Ingenuity Systems, Inc. All rights reserved." Symbol Entrez Gene Name Affymetrix p-value Fold Change Location Type COL4A2 " collagen, type IV, alpha 2" COL4A2 0 1.255 Extracellular Space other ZAP70 zeta-chain (TCR) associated protein kinase 70kDa ZAP70 0.0004 1.258 Plasma Membrane kinase SVIL supervillin SVIL 0.0005 1.675 Plasma Membrane other PNKP polynucleotide kinase 3'-phosphatase PNKP 0.0006 -1.242 Nucleus kinase KIAA1949 KIAA1949 KIAA1949 0.0006 1.554 Unknown other C11ORF30 chromosome 11 open reading frame 30 C11orf30 0.0008 -1.122 Nucleus other GADD45B " growth arrest and DNA-damage-inducible, beta" GADD45B 0.001 2.601 Cytoplasm other KIAA1009 KIAA1009 KIAA1009 0.0011 -1.333 Nucleus other DDO D-aspartate oxidase DDO 0.0012 -1.302 Cytoplasm enzyme ATP6V0D2 " ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2" ATP6V0D2 0.0014 1.093 Unknown transporter PIPOX pipecolic acid oxidase PIPOX 0.0014 -1.209 Cytoplasm enzyme SRR serine racemase SRR 0.0016 1.233 Cytoplasm enzyme CLEC11A " C-type lectin domain family 11, member A" CLEC11A 0.002 1.326 Extracellular Space growth factor CNOT2 " CCR4-NOT transcription complex, subunit 2" CNOT2 0.0023 -1.176 Nucleus transcription regulator CD44 CD44 molecule (Indian blood group) CD44 0.0024 1.461 Plasma Membrane other MINA MYC induced nuclear antigen MINA 0.0025 1.096 Nucleus other SRGN serglycin SRGN 0.0027 2.31 Extracellular Space other CSDA cold shock domain protein A CSDA 0.0028 2.782 Nucleus transcription regulator FBXW5 F-box and WD repeat domain containing 5 FBXW5 0.0029 1.09 Cytoplasm other CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 CDC42EP4 0.003 1.356 Cytoplasm other NPAS4 neuronal PAS domain protein 4 NPAS4 0.0032 1.569 Nucleus transcription regulator PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 PRPSAP1 0.0033 -1.128 Extracellular Space other AKAP3 A kinase (PRKA) anchor protein 3 AKAP3 0.0034 -1.246 Cytoplasm other ICAM1 intercellular adhesion molecule 1 ICAM1 0.0034 1.937 Plasma Membrane transmembrane receptor FCGR1B " Fc fragment of IgG, high affinity Ib, receptor (CD64)" FCGR1B 0.0034 2.596 Plasma Membrane transmembrane receptor LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog LYN 0.0038 1.591 Cytoplasm kinase PTPLA " protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A" PTPLA 0.0038 -1.193 Unknown phosphatase HSPB8 heat shock 22kDa protein 8 HSPB8 0.0039 1.513 Cytoplasm kinase FAM110B " family with sequence similarity 110, member B" FAM110B 0.004 1.347 Unknown other MTBP " Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa" MTBP 0.004 -1.199 Unknown other TGFB1 " transforming growth factor, beta 1" TGFB1 0.004 1.467 Extracellular Space growth factor CSF2RA (includes EG:1438) " colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)" CSF2RA 0.004 1.323 Plasma Membrane transmembrane receptor ACOT9 acyl-CoA thioesterase 9 ACOT9 0.0041 1.303 Cytoplasm enzyme MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 0.0041 1.163 Nucleus kinase CRTC2 CREB regulated transcription coactivator 2 CRTC2 0.0043 1.121 Nucleus other CENPF " centromere protein F, 350/400ka (mitosin)" CENPF 0.0043 -1.235 Nucleus other COL4A1 " collagen, type IV, alpha 1" COL4A1 0.0045 1.514 Extracellular Space other FSTL3 follistatin-like 3 (secreted glycoprotein) FSTL3 0.0045 1.498 Extracellular Space other MED28 mediator complex subunit 28 MED28 0.0048 -1.198 Nucleus other MYCBP c-myc binding protein MYCBP 0.005 -1.168 Nucleus transcription regulator PBEF1 nicotinamide phosphoribosyltransferase PBEF1 0.005 2.413 Extracellular Space cytokine ADAMTS9 " ADAM metallopeptidase with thrombospondin type 1 motif, 9" ADAMTS9 0.0052 1.656 Extracellular Space peptidase SLC29A2 " solute carrier family 29 (nucleoside transporters), member 2" SLC29A2 0.0053 -1.102 Cytoplasm transporter SYT9 synaptotagmin IX SYT9 0.0055 -1.118 Plasma Membrane transporter FZD1 frizzled homolog 1 (Drosophila) FZD1 0.0056 -1.453 Plasma Membrane G-protein coupled receptor ADCY7 adenylate cyclase 7 ADCY7 0.0058 1.237 Plasma Membrane enzyme SLC25A25 " solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25" SLC25A25 0.006 1.353 Cytoplasm transporter SNX1 sorting nexin 1 SNX1 0.0061 -1.289 Cytoplasm transporter OVOL1 ovo-like 1(Drosophila) OVOL1 0.0062 1.138 Nucleus transcription regulator RPLP1 " ribosomal protein, large, P1" RPLP1 0.0067 1.122 Cytoplasm other NFATC2 " nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" NFATC2 0.0068 1.196 Nucleus transcription regulator YARS tyrosyl-tRNA synthetase YARS 0.0069 1.281 Cytoplasm enzyme GADD45A " growth arrest and DNA-damage-inducible, alpha" GADD45A 0.0071 2.319 Nucleus other ARHGAP8 Rho GTPase activating protein 8 ARHGAP8 0.0072 1.369 Cytoplasm other NTHL1 nth endonuclease III-like 1 (E. coli) NTHL1 0.0073 -1.218 Nucleus enzyme HCK hemopoietic cell kinase HCK 0.0074 1.875 Cytoplasm kinase KRT17 keratin 17 KRT17 0.0079 -1.301 Cytoplasm other TNFAIP3 " tumor necrosis factor, alpha-induced protein 3" TNFAIP3 0.008 1.39 Nucleus other HDGF hepatoma-derived growth factor (high-mobility group protein 1-like) HDGF 0.0082 1.162 Extracellular Space growth factor RBMS1 " RNA binding motif, single stranded interacting protein 1" RBMS1 0.0084 1.31 Nucleus other MDM4 Mdm4 p53 binding protein homolog (mouse) MDM4 0.0086 -1.279 Nucleus other HCST hematopoietic cell signal transducer HCST 0.0087 1.579 Plasma Membrane other MIB2 mindbomb homolog 2 (Drosophila) MIB2 0.0088 1.324 Nucleus transcription regulator ZIC1 " Zic family member 1 (odd-paired homolog, Drosophila)" ZIC1 0.0092 2.111 Nucleus transcription regulator LAPTM5 lysosomal multispanning membrane protein 5 LAPTM5 0.0092 2.498 Plasma Membrane other NDE1 nudE nuclear distribution gene E homolog 1 (A. nidulans) NDE1 0.0093 -1.489 Nucleus other RGS10 regulator of G-protein signaling 10 RGS10 0.0095 2.041 Cytoplasm other PICALM phosphatidylinositol binding clathrin assembly protein PICALM 0.0095 -1.217 Cytoplasm other TMPRSS3 " transmembrane protease, serine 3" TMPRSS3 0.0097 1.179 Plasma Membrane peptidase ASXL1 additional sex combs like 1 (Drosophila) ASXL1 0.0098 1.138 Nucleus other EARS2 " glutamyl-tRNA synthetase 2, mitochondrial (putative)" EARS2 0.0102 -1.242 Unknown enzyme TIMP1 TIMP metallopeptidase inhibitor 1 TIMP1 0.0102 2.259 Extracellular Space other DSE dermatan sulfate epimerase DSE 0.0104 1.5 Cytoplasm other ZSCAN21 zinc finger and SCAN domain containing 21 ZSCAN21 0.0105 -1.15 Nucleus transcription regulator FES feline sarcoma oncogene FES 0.0109 1.218 Cytoplasm kinase AHNAK AHNAK nucleoprotein AHNAK 0.0112 1.329 Nucleus other TOM1L1 target of myb1 (chicken)-like 1 TOM1L1 0.0114 -1.108 Cytoplasm other FOXP2 (includes EG:93986) forkhead box P2 FOXP2 0.0116 -1.208 Nucleus transcription regulator LIMK2 LIM domain kinase 2 LIMK2 0.0118 1.275 Cytoplasm kinase NODAL nodal homolog (mouse) NODAL 0.012 1.18 Extracellular Space growth factor RPL36AL ribosomal protein L36a-like RPL36AL 0.012 1.124 Cytoplasm other SOCS3 suppressor of cytokine signaling 3 SOCS3 0.012 5.199 Cytoplasm other PITPNC1 " phosphatidylinositol transfer protein, cytoplasmic 1" PITPNC1 0.0121 1.58 Cytoplasm transporter DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 DDX17 0.0124 -1.941 Nucleus enzyme RPL22 ribosomal protein L22 RPL22 0.0127 1.12 Nucleus other USP37 ubiquitin specific peptidase 37 USP37 0.0127 -1.319 Nucleus peptidase FAM152A " family with sequence similarity 152, member A" C1orf121 0.0129 1.07 Unknown other HDAC5 histone deacetylase 5 HDAC5 0.0129 -1.128 Nucleus transcription regulator FOSB FBJ murine osteosarcoma viral oncogene homolog B FOSB 0.0131 1.487 Nucleus transcription regulator LY86 lymphocyte antigen 86 LY86 0.0132 1.278 Plasma Membrane other INSM1 insulinoma-associated 1 INSM1 0.0134 -1.283 Nucleus other CXCL14 chemokine (C-X-C motif) ligand 14 CXCL14 0.0135 2.259 Extracellular Space cytokine SLC34A1 " solute carrier family 34 (sodium phosphate), member 1" SLC34A1 0.0135 -1.109 Plasma Membrane transporter BMP8B bone morphogenetic protein 8b BMP8B 0.0136 -1.305 Extracellular Space growth factor C1QTNF5 C1q and tumor necrosis factor related protein 5 C1QTNF5 0.0136 1.283 Plasma Membrane transmembrane receptor FCER1G " Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide" FCER1G 0.0137 2.234 Plasma Membrane transmembrane receptor BNIPL BCL2/adenovirus E1B 19kD interacting protein like BNIPL 0.0141 1.091 Cytoplasm other PLS1 (includes EG:5357) plastin 1 (I isoform) PLS1 0.0141 -1.191 Cytoplasm other BBS9 Bardet-Biedl syndrome 9 BBS9 0.0142 -1.198 Extracellular Space other ARRB1 " arrestin, beta 1" ARRB1 0.0144 -1.406 Cytoplasm other NR1D2 " nuclear receptor subfamily 1, group D, member 2" NR1D2 0.0146 -1.486 Nucleus ligand-dependent nuclear receptor ITGB3 " integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ITGB3 0.0147 -1.281 Plasma Membrane transmembrane receptor ARHGEF2 rho/rac guanine nucleotide exchange factor (GEF) 2 ARHGEF2 0.015 -1.321 Cytoplasm other DUSP8 dual specificity phosphatase 8 DUSP8 0.0151 1.238 Nucleus phosphatase NID1 nidogen 1 NID1 0.0151 2.665 Extracellular Space other IFITM2 interferon induced transmembrane protein 2 (1-8D) IFITM2 0.0155 2.043 Plasma Membrane other PLD1 " phospholipase D1, phosphatidylcholine-specific" PLD1 0.0155 -1.241 Cytoplasm enzyme SULT2A1 " sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1" SULT2A1 0.0158 1.054 Cytoplasm enzyme BRWD1 bromodomain and WD repeat domain containing 1 BRWD1 0.016 -1.358 Nucleus transcription regulator FCGR1A " Fc fragment of IgG, high affinity Ia, receptor (CD64)" FCGR1A 0.0161 2.095 Plasma Membrane transmembrane receptor ANXA2 annexin A2 ANXA2 0.0163 1.709 Plasma Membrane other RWDD2B RWD domain containing 2B RWDD2B 0.0163 -1.412 Unknown other RAC2 " ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" RAC2 0.0166 1.343 Cytoplasm enzyme TEKT1 tektin 1 TEKT1 0.0168 1.152 Cytoplasm other PIK3CB " phosphoinositide-3-kinase, catalytic, beta polypeptide" PIK3CB 0.0169 -1.095 Cytoplasm kinase ACTC1 " actin, alpha, cardiac muscle 1" ACTC1 0.017 1.16 Cytoplasm other FXYD3 FXYD domain containing ion transport regulator 3 FXYD3 0.017 1.212 Plasma Membrane ion channel AP4B1 " adaptor-related protein complex 4, beta 1 subunit" AP4B1 0.0171 -1.405 Cytoplasm transporter CDKN1A " cyclin-dependent kinase inhibitor 1A (p21, Cip1)" CDKN1A 0.0171 1.612 Nucleus kinase ENSA endosulfine alpha ENSA 0.0174 -1.32 Unknown transporter TRIM15 tripartite motif-containing 15 TRIM15 0.0175 -1.222 Unknown other MED12 mediator complex subunit 12 MED12 0.0178 -1.159 Nucleus transcription regulator TRPM7 " transient receptor potential cation channel, subfamily M, member 7" TRPM7 0.018 -1.291 Plasma Membrane kinase EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 EIF2AK1 0.0184 -1.557 Cytoplasm kinase FPR1 formyl peptide receptor 1 FPR1 0.0184 2.3 Plasma Membrane G-protein coupled receptor MS4A7 " membrane-spanning 4-domains, subfamily A, member 7" MS4A7 0.0184 2.868 Unknown other SAG S-antigen; retina and pineal gland (arrestin) SAG 0.0184 1.19 Cytoplasm other RIPK2 receptor-interacting serine-threonine kinase 2 RIPK2 0.0185 1.17 Plasma Membrane kinase FAM129A " family with sequence similarity 129, member A" FAM129A 0.0186 1.514 Unknown other TAGLN transgelin TAGLN 0.0187 1.6 Cytoplasm other NCF2 neutrophil cytosolic factor 2 NCF2 0.0189 1.331 Cytoplasm enzyme LRRN2 leucine rich repeat neuronal 2 LRRN2 0.019 -1.221 Plasma Membrane other FCGR2A " Fc fragment of IgG, low affinity IIa, receptor (CD32)" FCGR2A 0.0193 2.067 Plasma Membrane transmembrane receptor DCN decorin DCN 0.0195 1.508 Extracellular Space other ACTA2 (includes EG:59) " actin, alpha 2, smooth muscle, aorta" ACTA2 0.0197 1.734 Cytoplasm other SYNE1 " spectrin repeat containing, nuclear envelope 1" SYNE1 0.0197 -1.315 Nucleus other PDPN podoplanin PDPN 0.0204 1.144 Plasma Membrane transporter KIF5B kinesin family member 5B KIF5B 0.0205 -1.358 Cytoplasm other OTUD7B OTU domain containing 7B OTUD7B 0.021 -1.291 Cytoplasm peptidase MEIS1 Meis homeobox 1 MEIS1 0.0211 -1.525 Nucleus transcription regulator ACOX3 " acyl-Coenzyme A oxidase 3, pristanoyl" ACOX3 0.0212 1.121 Cytoplasm enzyme JUNB jun B proto-oncogene JUNB 0.0215 1.825 Nucleus transcription regulator ADORA1 adenosine A1 receptor ADORA1 0.0219 -1.321 Plasma Membrane G-protein coupled receptor RNASE7 " ribonuclease, RNase A family, 7" RNASE7 0.0219 1.065 Extracellular Space enzyme EIF3K " eukaryotic translation initiation factor 3, subunit K" EIF3K 0.0221 -1.122 Cytoplasm translation regulator THBS1 thrombospondin 1 THBS1 0.0222 1.211 Extracellular Space other UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) UPF3A 0.0222 1.286 Nucleus transporter ADAM22 ADAM metallopeptidase domain 22 ADAM22 0.0223 1.123 Plasma Membrane peptidase NLRP3 " NLR family, pyrin domain containing 3" NLRP3 0.0225 1.187 Cytoplasm other ZBTB10 zinc finger and BTB domain containing 10 ZBTB10 0.0226 -1.358 Nucleus other NSD1 -- NSD1 0.0227 -1.269 Nucleus transcription regulator PPAT phosphoribosyl pyrophosphate amidotransferase PPAT 0.0227 -1.423 Cytoplasm enzyme SAT1 spermidine/spermine N1-acetyltransferase 1 SAT1 0.0227 1.478 Cytoplasm enzyme CH25H cholesterol 25-hydroxylase CH25H 0.0229 1.924 Cytoplasm enzyme WWP2 WW domain containing E3 ubiquitin protein ligase 2 WWP2 0.0229 1.163 Cytoplasm enzyme CSF3R colony stimulating factor 3 receptor (granulocyte) CSF3R 0.023 1.212 Plasma Membrane transmembrane receptor CLIC1 chloride intracellular channel 1 CLIC1 0.0233 1.491 Nucleus ion channel REG3A regenerating islet-derived 3 alpha REG3A 0.0233 1.226 Extracellular Space growth factor TMOD1 tropomodulin 1 TMOD1 0.0233 1.18 Cytoplasm enzyme OVOL2 ovo-like 2 (Drosophila) OVOL2 0.0234 1.149 Nucleus transcription regulator GALNT2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) GALNT2 0.0235 1.338 Cytoplasm enzyme ZFP36 " zinc finger protein 36, C3H type, homolog (mouse)" ZFP36 0.0235 2.269 Nucleus transcription regulator IRF1 interferon regulatory factor 1 IRF1 0.0238 1.488 Nucleus transcription regulator CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) CDC14B 0.0239 -1.101 Nucleus phosphatase TDRD3 tudor domain containing 3 TDRD3 0.0239 -1.215 Unknown other USP5 ubiquitin specific peptidase 5 (isopeptidase T) USP5 0.024 1.107 Cytoplasm peptidase FEZF2 FEZ family zinc finger 2 FEZF2 0.0242 -1.614 Unknown other CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 CHST7 0.0246 1.359 Cytoplasm enzyme COG4 component of oligomeric golgi complex 4 COG4 0.0247 -1.226 Cytoplasm transporter CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) CNDP2 0.0249 1.069 Cytoplasm peptidase MLLT4 " myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4" MLLT4 0.0249 -1.333 Nucleus other COX5A cytochrome c oxidase subunit Va COX5A 0.0251 1.12 Cytoplasm enzyme TRIM66 tripartite motif-containing 66 TRIM66 0.0252 1.198 Nucleus transcription regulator LST1 leukocyte specific transcript 1 LST1 0.0255 1.261 Plasma Membrane other PER1 period homolog 1 (Drosophila) PER1 0.0256 1.179 Nucleus other TAF8 " TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa" TAF8 0.0256 -1.141 Nucleus transcription regulator LAIR1 leukocyte-associated immunoglobulin-like receptor 1 LAIR1 0.0257 1.37 Plasma Membrane transmembrane receptor ZFYVE16 " zinc finger, FYVE domain containing 16" ZFYVE16 0.0258 -1.19 Nucleus transporter HDAC7A histone deacetylase 7 HDAC7A 0.0259 1.203 Nucleus transcription regulator SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) SUV420H1 0.026 -1.462 Nucleus enzyme CARHSP1 " calcium regulated heat stable protein 1, 24kDa" CARHSP1 0.0262 -1.363 Cytoplasm other OXTR oxytocin receptor OXTR 0.0262 1.312 Plasma Membrane G-protein coupled receptor PPP2R1B " protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform" PPP2R1B 0.0263 -1.188 Unknown phosphatase ZFPM1 " zinc finger protein, multitype 1" ZFPM1 0.0263 1.305 Nucleus transcription regulator ZYX zyxin ZYX 0.0263 1.229 Plasma Membrane other GFPT1 glutamine-fructose-6-phosphate transaminase 1 GFPT1 0.0264 1.191 Cytoplasm enzyme CXCL16 chemokine (C-X-C motif) ligand 16 CXCL16 0.0265 1.286 Extracellular Space cytokine TF transferrin TF 0.0265 -1.144 Extracellular Space transporter MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) MAFF 0.0267 2.105 Nucleus transcription regulator IFIT2 interferon-induced protein with tetratricopeptide repeats 2 IFIT2 0.027 -1.241 Unknown other SCARA3 " scavenger receptor class A, member 3" SCARA3 0.0271 1.54 Plasma Membrane transmembrane receptor GCKR glucokinase (hexokinase 4) regulator GCKR 0.0273 1.177 Nucleus other JAK3 " Janus kinase 3 (a protein tyrosine kinase, leukocyte)" JAK3 0.0274 1.361 Cytoplasm kinase TCF7L1 " transcription factor 7-like 1 (T-cell specific, HMG-box)" TCF7L1 0.0274 1.306 Nucleus transcription regulator CUL4B cullin 4B CUL4B 0.0275 1.269 Unknown other ZNF91 zinc finger protein 91 ZNF91 0.0275 -1.587 Nucleus transcription regulator PIM1 pim-1 oncogene PIM1 0.0276 1.252 Cytoplasm kinase PCTK1 PCTAIRE protein kinase 1 PCTK1 0.0277 -1.106 Cytoplasm kinase DPYSL3 dihydropyrimidinase-like 3 DPYSL3 0.0278 -1.473 Cytoplasm enzyme HCLS1 hematopoietic cell-specific Lyn substrate 1 HCLS1 0.0278 2.45 Nucleus transcription regulator CYBA " cytochrome b-245, alpha polypeptide" CYBA 0.0279 1.713 Cytoplasm enzyme MED6 mediator complex subunit 6 MED6 0.0281 -1.153 Nucleus transcription regulator SERPINA1 " serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1" SERPINA1 0.0281 2.181 Extracellular Space other BRD4 bromodomain containing 4 BRD4 0.0284 -1.165 Nucleus kinase HLA-DPB1 " major histocompatibility complex, class II, DP beta 1" HLA-DPB1 0.0285 1.667 Plasma Membrane transmembrane receptor TYROBP TYRO protein tyrosine kinase binding protein TYROBP 0.0285 2.294 Plasma Membrane other IFITM3 interferon induced transmembrane protein 3 (1-8U) IFITM3 0.0286 1.776 Plasma Membrane other ANPEP alanyl (membrane) aminopeptidase ANPEP 0.0287 -1.173 Plasma Membrane peptidase CCNC cyclin C CCNC 0.0287 1.183 Nucleus other MTMR15 myotubularin related protein 15 MTMR15 0.0288 -1.252 Unknown other ICAM3 intercellular adhesion molecule 3 ICAM3 0.0292 1.344 Plasma Membrane other POLR1C " polymerase (RNA) I polypeptide C, 30kDa" POLR1C 0.0293 -1.112 Nucleus enzyme PRKCQ " protein kinase C, theta" PRKCQ 0.0293 -1.437 Cytoplasm kinase ADAM30 ADAM metallopeptidase domain 30 ADAM30 0.0296 -1.159 Plasma Membrane peptidase ALDH1L1 " aldehyde dehydrogenase 1 family, member L1" ALDH1L1 0.0296 1.245 Cytoplasm enzyme PKN2 protein kinase N2 PKN2 0.0299 -1.131 Cytoplasm kinase VASN vasorin VASN 0.0301 1.431 Plasma Membrane other HIF1AN " hypoxia-inducible factor 1, alpha subunit inhibitor" HIF1AN 0.0303 -1.354 Nucleus enzyme IL6 " interleukin 6 (interferon, beta 2)" IL6 0.0303 1.232 Extracellular Space cytokine ZNF155 zinc finger protein 155 ZNF155 0.0304 -1.261 Nucleus transcription regulator SP1 Sp1 transcription factor SP1 0.0306 -1.099 Nucleus transcription regulator XPO5 exportin 5 XPO5 0.0306 1.146 Nucleus transporter SNF1LK2 SNF1-like kinase 2 SNF1LK2 0.0308 1.191 Cytoplasm kinase AKR1C2 " aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)" AKR1C2 0.031 1.166 Cytoplasm enzyme ARHGAP22 Rho GTPase activating protein 22 ARHGAP22 0.0311 -1.227 Cytoplasm other RPS24 (includes EG:6229) ribosomal protein S24 RPS24 0.0311 1.098 Cytoplasm other CEBPD " CCAAT/enhancer binding protein (C/EBP), delta" CEBPD 0.0312 1.794 Nucleus transcription regulator MICA MHC class I polypeptide-related sequence A MICA 0.0312 1.502 Plasma Membrane other GALK1 galactokinase 1 GALK1 0.0313 1.1 Cytoplasm kinase SLC7A7 " solute carrier family 7 (cationic amino acid transporter, y+ system), member 7" SLC7A7 0.0314 1.161 Plasma Membrane transporter COQ7 " coenzyme Q7 homolog, ubiquinone (yeast)" COQ7 0.0316 1.139 Cytoplasm other P2RX7 " purinergic receptor P2X, ligand-gated ion channel, 7" P2RX7 0.0316 -1.501 Plasma Membrane ion channel PHKB (includes EG:5257) " phosphorylase kinase, beta" PHKB 0.0318 -1.158 Cytoplasm kinase FGL2 fibrinogen-like 2 FGL2 0.0319 1.589 Extracellular Space peptidase DBF4B DBF4 homolog B (S. cerevisiae) DBF4B 0.0323 -1.323 Nucleus other RUNX1 runt-related transcription factor 1 RUNX1 0.0326 1.388 Nucleus transcription regulator CCBL1 " cysteine conjugate-beta lyase, cytoplasmic" CCBL1 0.0327 1.127 Cytoplasm enzyme PAWR " PRKC, apoptosis, WT1, regulator" PAWR 0.0327 1.119 Nucleus transcription regulator HRC histidine rich calcium binding protein HRC 0.0328 1.064 Cytoplasm other LRRC8C " leucine rich repeat containing 8 family, member C" LRRC8C 0.033 -1.17 Cytoplasm other LRRC37A3 " leucine rich repeat containing 37, member A3" LRRC37A3 0.0331 -1.146 Unknown other IL4R interleukin 4 receptor IL4R 0.0332 1.328 Plasma Membrane transmembrane receptor ABCD2 " ATP-binding cassette, sub-family D (ALD), member 2" ABCD2 0.0333 -1.182 Cytoplasm transporter ACOX1 " acyl-Coenzyme A oxidase 1, palmitoyl" ACOX1 0.0333 -1.394 Cytoplasm enzyme RIN2 Ras and Rab interactor 2 RIN2 0.0334 1.193 Cytoplasm other TCEA2 " transcription elongation factor A (SII), 2" TCEA2 0.0337 1.254 Nucleus transcription regulator AIF1 allograft inflammatory factor 1 AIF1 0.0338 1.613 Nucleus other WNT2B " wingless-type MMTV integration site family, member 2B" WNT2B 0.034 -1.152 Extracellular Space other C1ORF34 tetratricopeptide repeat domain 39A C1orf34 0.0341 -1.371 Unknown other AKAP13 A kinase (PRKA) anchor protein 13 AKAP13 0.0342 1.179 Cytoplasm other AFF1 " AF4/FMR2 family, member 1" AFF1 0.0343 1.166 Nucleus transcription regulator DBNL drebrin-like DBNL 0.0344 -1.168 Cytoplasm other IL10 interleukin 10 IL10 0.0344 1.106 Extracellular Space cytokine RPS13 ribosomal protein S13 RPS13 0.0347 1.124 Cytoplasm other FCGR3B " Fc fragment of IgG, low affinity IIIb, receptor (CD16b)" FCGR3B 0.0348 1.391 Plasma Membrane transmembrane receptor RND3 Rho family GTPase 3 RND3 0.0349 1.665 Cytoplasm enzyme SPTLC2 (includes EG:9517) " serine palmitoyltransferase, long chain base subunit 2" SPTLC2 0.0349 -1.488 Cytoplasm enzyme SLITRK2 " SLIT and NTRK-like family, member 2" SLITRK2 0.0351 -1.511 Unknown other CLEC7A " C-type lectin domain family 7, member A" CLEC7A 0.0352 1.474 Plasma Membrane transmembrane receptor SLC9A3R1 " solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1" SLC9A3R1 0.0352 1.308 Plasma Membrane other BAG3 BCL2-associated athanogene 3 BAG3 0.0353 1.692 Cytoplasm other ATP1B3 " ATPase, Na+/K+ transporting, beta 3 polypeptide" ATP1B3 0.0357 1.368 Plasma Membrane transporter CISH cytokine inducible SH2-containing protein CISH 0.0358 1.238 Cytoplasm other NCOA7 nuclear receptor coactivator 7 NCOA7 0.0362 -1.12 Nucleus other PTPRC " protein tyrosine phosphatase, receptor type, C" PTPRC 0.0362 2.19 Plasma Membrane phosphatase IKZF2 IKAROS family zinc finger 2 (Helios) IKZF2 0.0363 -1.627 Nucleus transcription regulator IL7R interleukin 7 receptor IL7R 0.0364 1.095 Plasma Membrane transmembrane receptor TBXAS1 thromboxane A synthase 1 (platelet) TBXAS1 0.0364 1.433 Plasma Membrane enzyme VPRBP Vpr (HIV-1) binding protein VPRBP 0.0365 1.277 Unknown other DNAJB5 " DnaJ (Hsp40) homolog, subfamily B, member 5" DNAJB5 0.0366 1.262 Unknown other HYI hydroxypyruvate isomerase homolog (E. coli) HYI 0.0366 1.089 Unknown enzyme MPO myeloperoxidase MPO 0.0366 1.133 Cytoplasm enzyme CYP2J2 " cytochrome P450, family 2, subfamily J, polypeptide 2" CYP2J2 0.0367 -1.412 Cytoplasm enzyme MED17 mediator complex subunit 17 MED17 0.0367 -1.156 Nucleus transcription regulator TLR2 toll-like receptor 2 TLR2 0.0367 1.448 Plasma Membrane transmembrane receptor RNASE6 " ribonuclease, RNase A family, k6" RNASE6 0.0369 1.71 Extracellular Space enzyme ZFP36L2 " zinc finger protein 36, C3H type-like 2" ZFP36L2 0.0369 2.151 Nucleus transcription regulator HMGA1 high mobility group AT-hook 1 HMGA1 0.037 1.25 Nucleus transcription regulator SKP2 S-phase kinase-associated protein 2 (p45) SKP2 0.0371 1.121 Nucleus other EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 EIF4EBP1 0.0372 1.368 Cytoplasm translation regulator PARVG " parvin, gamma" PARVG 0.0375 1.411 Cytoplasm other PDCL phosducin-like PDCL 0.0378 -1.134 Cytoplasm enzyme IPO9 importin 9 IPO9 0.038 1.101 Nucleus transporter MED20 mediator complex subunit 20 MED20 0.038 -1.195 Nucleus transcription regulator TNFRSF1A " tumor necrosis factor receptor superfamily, member 1A" TNFRSF1A 0.038 1.386 Plasma Membrane transmembrane receptor PIGG " phosphatidylinositol glycan anchor biosynthesis, class G" PIGG 0.0381 1.14 Cytoplasm other DGCR14 DiGeorge syndrome critical region gene 14 DGCR14 0.0382 -1.454 Nucleus other CYP2U1 " cytochrome P450, family 2, subfamily U, polypeptide 1" CYP2U1 0.0383 -1.158 Unknown enzyme EMP1 epithelial membrane protein 1 EMP1 0.0385 1.22 Plasma Membrane other HEXIM1 hexamethylene bis-acetamide inducible 1 HEXIM1 0.0385 -1.53 Nucleus transcription regulator DPH5 DPH5 homolog (S. cerevisiae) DPH5 0.0387 -1.237 Unknown enzyme EGR2 " early growth response 2 (Krox-20 homolog, Drosophila)" EGR2 0.0387 1.247 Nucleus transcription regulator GM2A GM2 ganglioside activator GM2A 0.0387 -1.081 Cytoplasm enzyme HMOX2 heme oxygenase (decycling) 2 HMOX2 0.0387 -1.15 Cytoplasm enzyme TNS3 tensin 3 TNS3 0.0387 -1.389 Unknown phosphatase CD4 CD4 molecule CD4 0.0393 1.312 Plasma Membrane transmembrane receptor FBXO15 F-box protein 15 FBXO15 0.0395 -1.324 Unknown other IRF6 interferon regulatory factor 6 IRF6 0.0395 1.151 Nucleus transcription regulator DHFR dihydrofolate reductase DHFR 0.0396 -1.38 Unknown enzyme RPL35A ribosomal protein L35a RPL35A 0.04 1.073 Cytoplasm other TYRO3 TYRO3 protein tyrosine kinase TYRO3 0.0401 -1.24 Plasma Membrane kinase HLA-DRB1 " major histocompatibility complex, class II, DR beta 1" HLA-DRB1 0.0402 1.693 Plasma Membrane transmembrane receptor CCR1 chemokine (C-C motif) receptor 1 CCR1 0.0405 1.49 Plasma Membrane G-protein coupled receptor NPHP3 nephronophthisis 3 (adolescent) NPHP3 0.0406 1.146 Unknown other TTF2 " transcription termination factor, RNA polymerase II" TTF2 0.0406 -1.085 Nucleus transcription regulator CD93 CD93 molecule CD93 0.0407 1.909 Plasma Membrane other CDH6 " cadherin 6, type 2, K-cadherin (fetal kidney)" CDH6 0.0407 -1.289 Plasma Membrane other LRRC1 leucine rich repeat containing 1 LRRC1 0.0408 -1.481 Cytoplasm other PIK3R3 " phosphoinositide-3-kinase, regulatory subunit 3 (gamma)" PIK3R3 0.0408 1.228 Cytoplasm kinase ANKRD15 KN motif and ankyrin repeat domains 1 ANKRD15 0.0411 1.061 Nucleus transcription regulator GART " phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" GART 0.0412 -1.367 Cytoplasm enzyme SOX1 SRY (sex determining region Y)-box 1 SOX1 0.0412 1.479 Nucleus transcription regulator ELMOD2 ELMO/CED-12 domain containing 2 ELMOD2 0.0413 -1.11 Unknown other HYDIN hydrocephalus inducing homolog (mouse) HYDIN 0.0414 1.09 Unknown other IFT172 intraflagellar transport 172 homolog (Chlamydomonas) IFT172 0.0414 -1.219 Nucleus other ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 ARNTL2 0.0417 -1.321 Nucleus transcription regulator MKLN1 " muskelin 1, intracellular mediator containing kelch motifs" MKLN1 0.0417 -1.29 Cytoplasm other PLA2G5 " phospholipase A2, group V" PLA2G5 0.0418 1.188 Extracellular Space enzyme HEYL hairy/enhancer-of-split related with YRPW motif-like HEYL 0.042 1.198 Nucleus transcription regulator HOXC10 homeobox C10 HOXC10 0.0421 -1.165 Nucleus transcription regulator CAPRIN2 caprin family member 2 CAPRIN2 0.0425 1.226 Cytoplasm other ALG1 " asparagine-linked glycosylation 1 homolog (S. cerevisiae, beta-1,4-mannosyltransferase)" ALG1 0.0426 1.222 Cytoplasm enzyme HAPLN3 hyaluronan and proteoglycan link protein 3 HAPLN3 0.0428 1.174 Extracellular Space other DMD dystrophin DMD 0.0429 1.064 Plasma Membrane other HAMP hepcidin antimicrobial peptide HAMP 0.0429 2.051 Extracellular Space other INTS7 integrator complex subunit 7 INTS7 0.0429 -1.4 Unknown other FZD5 frizzled homolog 5 (Drosophila) FZD5 0.0431 -1.429 Plasma Membrane G-protein coupled receptor MSI2 musashi homolog 2 (Drosophila) MSI2 0.0432 -1.204 Cytoplasm other MAN1A2 " mannosidase, alpha, class 1A, member 2" MAN1A2 0.0433 -1.294 Cytoplasm enzyme JAG1 jagged 1 (Alagille syndrome) JAG1 0.0435 1.807 Extracellular Space growth factor RDH10 retinol dehydrogenase 10 (all-trans) RDH10 0.0436 1.171 Unknown enzyme FRAS1 Fraser syndrome 1 FRAS1 0.0437 -1.831 Extracellular Space other KLF9 Kruppel-like factor 9 KLF9 0.0438 1.164 Nucleus transcription regulator ADAM28 ADAM metallopeptidase domain 28 ADAM28 0.0439 1.333 Plasma Membrane peptidase XDH xanthine dehydrogenase XDH 0.0439 1.161 Cytoplasm enzyme KIF2C kinesin family member 2C KIF2C 0.0441 1.092 Nucleus other BDH2 " 3-hydroxybutyrate dehydrogenase, type 2" BDH2 0.0442 -1.3 Extracellular Space enzyme SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 SLC25A2 0.0442 1.151 Cytoplasm transporter ATXN1 ataxin 1 ATXN1 0.0443 -1.343 Nucleus other FUS fusion (involved in t(12;16) in malignant liposarcoma) FUS 0.0443 1.116 Nucleus transcription regulator POLG " polymerase (DNA directed), gamma" POLG 0.0446 -1.203 Cytoplasm enzyme CYB561 cytochrome b-561 CYB561 0.0449 -1.25 Cytoplasm enzyme ANO6 anoctamin 6 TMEM16F 0.045 1.108 Unknown other SIRT5 sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) SIRT5 0.0451 -1.209 Cytoplasm enzyme SLC11A1 " solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1" SLC11A1 0.0451 1.54 Plasma Membrane transporter GNB1L " guanine nucleotide binding protein (G protein), beta polypeptide 1-like" GNB1L 0.0452 1.187 Unknown other KRT5 keratin 5 KRT5 0.0452 1.142 Cytoplasm other MKL2 MKL/myocardin-like 2 MKL2 0.0455 1.343 Nucleus transcription regulator SHMT1 serine hydroxymethyltransferase 1 (soluble) SHMT1 0.0457 -1.143 Cytoplasm enzyme PLCE1 " phospholipase C, epsilon 1" PLCE1 0.0458 1.176 Cytoplasm enzyme CDH3 " cadherin 3, type 1, P-cadherin (placental)" CDH3 0.0459 1.302 Plasma Membrane other CCNL1 cyclin L1 CCNL1 0.046 -1.189 Nucleus other ZNF350 zinc finger protein 350 ZNF350 0.046 -1.269 Nucleus transcription regulator CLIC5 chloride intracellular channel 5 CLIC5 0.0462 -1.559 Cytoplasm ion channel IL13RA1 " interleukin 13 receptor, alpha 1" IL13RA1 0.0463 1.559 Plasma Membrane transmembrane receptor COL1A2 " collagen, type I, alpha 2" COL1A2 0.0465 1.371 Extracellular Space other HTATIP K(lysine) acetyltransferase 5 HTATIP 0.0465 1.141 Nucleus transcription regulator DNAH17 " dynein, axonemal, heavy chain 17" DNAH17 0.0466 -1.505 Cytoplasm other ARC activity-regulated cytoskeleton-associated protein ARC 0.0467 1.372 Cytoplasm other MYOZ2 myozenin 2 MYOZ2 0.0468 -1.082 Cytoplasm other CCR10 chemokine (C-C motif) receptor 10 CCR10 0.047 1.185 Plasma Membrane G-protein coupled receptor XPO7 exportin 7 XPO7 0.0471 1.103 Nucleus transporter AKNA AT-hook transcription factor AKNA 0.0473 1.15 Unknown other TNFRSF1B " tumor necrosis factor receptor superfamily, member 1B" TNFRSF1B 0.0473 1.653 Plasma Membrane transmembrane receptor APIP APAF1 interacting protein APIP 0.0474 1.136 Unknown other ODF2 outer dense fiber of sperm tails 2 ODF2 0.0475 1.296 Cytoplasm other SNF1LK SNF1-like kinase SNF1LK 0.0475 1.693 Cytoplasm kinase ATG7 ATG7 autophagy related 7 homolog (S. cerevisiae) ATG7 0.0476 1.268 Cytoplasm enzyme SMARCC1 " SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" SMARCC1 0.0477 -1.134 Nucleus transcription regulator CDKN1C " cyclin-dependent kinase inhibitor 1C (p57, Kip2)" CDKN1C 0.0479 -1.275 Nucleus other TRIM35 tripartite motif-containing 35 TRIM35 0.0479 -1.147 Cytoplasm other BTG2 " BTG family, member 2" BTG2 0.048 1.449 Nucleus transcription regulator GJB1 " gap junction protein, beta 1, 32kDa" GJB1 0.048 -1.339 Plasma Membrane transporter PCTK3 PCTAIRE protein kinase 3 PCTK3 0.0481 -2.071 Cytoplasm kinase TGDS " TDP-glucose 4,6-dehydratase" TGDS 0.0482 -1.249 Unknown enzyme C14ORF106 chromosome 14 open reading frame 106 C14orf106 0.0483 1.044 Nucleus other PDLIM4 PDZ and LIM domain 4 PDLIM4 0.0485 2.518 Cytoplasm other BLVRA biliverdin reductase A BLVRA 0.0486 1.244 Cytoplasm enzyme GPR56 G protein-coupled receptor 56 GPR56 0.0487 1.329 Plasma Membrane G-protein coupled receptor TGFBR1 " transforming growth factor, beta receptor 1" TGFBR1 0.0487 1.066 Plasma Membrane kinase ZNF326 zinc finger protein 326 ZNF326 0.0487 -1.175 Nucleus transcription regulator FGFR1OP FGFR1 oncogene partner FGFR1OP 0.049 -1.197 Cytoplasm other COX10 " COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)" COX10 0.0491 1.118 Cytoplasm enzyme F3 " coagulation factor III (thromboplastin, tissue factor)" F3 0.0491 2.922 Plasma Membrane transmembrane receptor SFXN5 sideroflexin 5 SFXN5 0.0491 1.09 Cytoplasm transporter IRAK3 interleukin-1 receptor-associated kinase 3 IRAK3 0.0492 1.125 Extracellular Space kinase PRKD2 protein kinase D2 PRKD2 0.0493 1.179 Cytoplasm kinase TLE3 " transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)" TLE3 0.0494 1.124 Nucleus other ZNF133 zinc finger protein 133 ZNF133 0.0494 -1.109 Nucleus transcription regulator ERGIC2 ERGIC and golgi 2 ERGIC2 0.0498 -1.064 Unknown other ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 0.0499 -1.171 Plasma Membrane enzyme ASXL3 additional sex combs like 3 (Drosophila) ASXL3 0.05 1.289 Unknown other ADM adrenomedullin -- Extracellular Space other AGT " angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" -- Extracellular Space other ALAS1 " aminolevulinate, delta-, synthase 1" -- Cytoplasm enzyme ALOX5AP arachidonate 5-lipoxygenase-activating protein -- Plasma Membrane other AR androgen receptor -- Nucleus ligand-dependent nuclear receptor ARHGAP1 Rho GTPase activating protein 1 -- Cytoplasm other ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -- Cytoplasm other ARPC5 " actin related protein 2/3 complex, subunit 5, 16kDa" -- Cytoplasm other ATRX " alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)" -- Nucleus transcription regulator BARD1 BRCA1 associated RING domain 1 -- Nucleus transcription regulator BIRC2 baculoviral IAP repeat-containing 2 -- Cytoplasm other BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -- Cytoplasm other BRCA1 " breast cancer 1, early onset" -- Nucleus transcription regulator BTG1 " B-cell translocation gene 1, anti-proliferative" -- Nucleus transcription regulator CAPN8 calpain 8 -- Cytoplasm peptidase CASP3 " caspase 3, apoptosis-related cysteine peptidase" -- Cytoplasm peptidase CASP8 " caspase 8, apoptosis-related cysteine peptidase" -- Nucleus peptidase CASP9 " caspase 9, apoptosis-related cysteine peptidase" -- Cytoplasm peptidase CBFA2T3 " core-binding factor, runt domain, alpha subunit 2; translocated to, 3" -- Nucleus transcription regulator CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence -- Nucleus transcription regulator CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b -- Nucleus other CBX5 " chromobox homolog 5 (HP1 alpha homolog, Drosophila)" -- Nucleus other CBX8 " chromobox homolog 8 (Pc class homolog, Drosophila)" -- Nucleus other CCNE2 (includes EG:9134) cyclin E2 -- Nucleus other CD38 CD38 molecule -- Plasma Membrane enzyme CD40LG CD40 ligand -- Extracellular Space cytokine CDC25A cell division cycle 25 homolog A (S. pombe) -- Nucleus phosphatase CDC7 cell division cycle 7 homolog (S. cerevisiae) -- Nucleus kinase CDH11 " cadherin 11, type 2, OB-cadherin (osteoblast)" -- Plasma Membrane other CDH2 " cadherin 2, type 1, N-cadherin (neuronal)" -- Plasma Membrane other CDKN2A " cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)" -- Nucleus transcription regulator CDT1 chromatin licensing and DNA replication factor 1 -- Nucleus other CEBPA " CCAAT/enhancer binding protein (C/EBP), alpha" -- Nucleus transcription regulator CEP350 centrosomal protein 350kDa -- Cytoplasm other CLCN3 chloride channel 3 -- Plasma Membrane ion channel CNOT6 " CCR4-NOT transcription complex, subunit 6" -- Nucleus other COG2 component of oligomeric golgi complex 2 -- Cytoplasm transporter COL4A3 (includes EG:1285) " collagen, type IV, alpha 3 (Goodpasture antigen)" -- Extracellular Space other CRYGA (includes EG:1418) " crystallin, gamma A" -- Unknown other CTNNB1 " catenin (cadherin-associated protein), beta 1, 88kDa" -- Nucleus transcription regulator CUL1 cullin 1 -- Nucleus enzyme CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) -- Extracellular Space cytokine DAD1 defender against cell death 1 -- Cytoplasm enzyme DDB1 " damage-specific DNA binding protein 1, 127kDa" -- Nucleus other DEF6 differentially expressed in FDCP 6 homolog (mouse) -- Extracellular Space other DLG1 " discs, large homolog 1 (Drosophila)" -- Plasma Membrane kinase DLG2 " discs, large homolog 2, chapsyn-110 (Drosophila)" -- Plasma Membrane kinase DLG4 " discs, large homolog 4 (Drosophila)" -- Plasma Membrane kinase DNAH2 " dynein, axonemal, heavy chain 2" -- Unknown other DYNC1I1 " dynein, cytoplasmic 1, intermediate chain 1" -- Cytoplasm other DYNLL1 " dynein, light chain, LC8-type 1" -- Cytoplasm other DYNLT1 " dynein, light chain, Tctex-type 1" -- Cytoplasm other DYNLT3 " dynein, light chain, Tctex-type 3" -- Cytoplasm other EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -- Cytoplasm translation regulator EIF4E eukaryotic translation initiation factor 4E -- Cytoplasm translation regulator ERBB2 " v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" -- Plasma Membrane kinase ERBB2IP erbb2 interacting protein -- Extracellular Space cytokine ERBB2IP PREDICTED erbb2 interacting protein -- Extracellular Space cytokine FAS " Fas (TNF receptor superfamily, member 6)" -- Plasma Membrane transmembrane receptor FBXO32 F-box protein 32 -- Cytoplasm enzyme FCGR3A " Fc fragment of IgG, low affinity IIIa, receptor (CD16a)" -- Plasma Membrane transmembrane receptor FGF2 fibroblast growth factor 2 (basic) -- Extracellular Space growth factor FIGLA folliculogenesis specific basic helix-loop-helix -- Nucleus other FRAP1 FK506 binding protein 12-rapamycin associated protein 1 -- Nucleus kinase FZD2 frizzled homolog 2 (Drosophila) -- Plasma Membrane G-protein coupled receptor GABARAP GABA(A) receptor-associated protein -- Cytoplasm transporter GALNAC4S-6ST B cell RAG associated protein -- Plasma Membrane enzyme GARS glycyl-tRNA synthetase -- Cytoplasm enzyme GBP1 (includes EG:2633) " guanylate binding protein 1, interferon-inducible, 67kDa" -- Cytoplasm enzyme GLI2 GLI-Kruppel family member GLI2 -- Nucleus transcription regulator GLI3 GLI-Kruppel family member GLI3 -- Nucleus transcription regulator GRIP1 glutamate receptor interacting protein 1 -- Plasma Membrane other HAVCR1 hepatitis A virus cellular receptor 1 -- Plasma Membrane other HDAC2 histone deacetylase 2 -- Nucleus transcription regulator HNF1A HNF1 homeobox A -- Nucleus transcription regulator HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -- Nucleus transporter HOXA9 homeobox A9 -- Nucleus transcription regulator HSP90AA1 " heat shock protein 90kDa alpha (cytosolic), class A member 1" -- Cytoplasm other HSPB1 heat shock 27kDa protein 1 -- Cytoplasm other IER2 immediate early response 2 -- Cytoplasm other IFNG " interferon, gamma" -- Extracellular Space cytokine IGF1 insulin-like growth factor 1 (somatomedin C) -- Extracellular Space growth factor IL13 interleukin 13 -- Extracellular Space cytokine IL1B " interleukin 1, beta" -- Extracellular Space cytokine IL4 interleukin 4 -- Extracellular Space cytokine INS1 insulin I -- Extracellular Space other ITPR1 " inositol 1,4,5-triphosphate receptor, type 1" -- Cytoplasm ion channel JARID1B " jumonji, AT rich interactive domain 1B" -- Nucleus transcription regulator KLRB1C killer cell lectin-like receptor subfamily B member 1C -- Plasma Membrane other KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog -- Cytoplasm enzyme LHCGR luteinizing hormone/choriogonadotropin receptor -- Plasma Membrane G-protein coupled receptor MARK3 MAP/microtubule affinity-regulating kinase 3 -- Cytoplasm kinase MCM5 minichromosome maintenance complex component 5 -- Nucleus enzyme MDM2 (includes EG:4193) Mdm2 p53 binding protein homolog (mouse) -- Nucleus transcription regulator MFRP membrane frizzled-related protein -- Plasma Membrane transmembrane receptor MLH1 " mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)" -- Nucleus other MMP2 " matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)" -- Extracellular Space peptidase MMP9 " matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" -- Extracellular Space peptidase MYC v-myc myelocytomatosis viral oncogene homolog (avian) -- Nucleus transcription regulator MYCBP2 MYC binding protein 2 -- Nucleus enzyme NCOR1 nuclear receptor co-repressor 1 -- Nucleus transcription regulator NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -- Cytoplasm enzyme NFAM1 NFAT activating protein with ITAM motif 1 -- Plasma Membrane transmembrane receptor NFE2 " nuclear factor (erythroid-derived 2), 45kDa" -- Nucleus transcription regulator NFE2L2 nuclear factor (erythroid-derived 2)-like 2 -- Nucleus transcription regulator NFYB " nuclear transcription factor Y, beta" -- Nucleus transcription regulator NPHP1 nephronophthisis 1 (juvenile) -- Nucleus other NR3C1 " nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)" -- Nucleus ligand-dependent nuclear receptor NR5A1 " nuclear receptor subfamily 5, group A, member 1" -- Nucleus ligand-dependent nuclear receptor OPRK1 " opioid receptor, kappa 1" -- Plasma Membrane G-protein coupled receptor PCBP2 poly(rC) binding protein 2 -- Nucleus other PDE4A " phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)" -- Cytoplasm enzyme PDGFRB " platelet-derived growth factor receptor, beta polypeptide" -- Plasma Membrane kinase PIAS3 " protein inhibitor of activated STAT, 3" -- Nucleus transcription regulator PIGF " phosphatidylinositol glycan anchor biosynthesis, class F" -- Cytoplasm enzyme PIGO " phosphatidylinositol glycan anchor biosynthesis, class O" -- Cytoplasm enzyme PLAT " plasminogen activator, tissue" -- Extracellular Space peptidase PLS3 plastin 3 (T isoform) -- Cytoplasm other PPP1CA " protein phosphatase 1, catalytic subunit, alpha isoform" -- Cytoplasm phosphatase PRDM5 PR domain containing 5 -- Nucleus other PRKDC " protein kinase, DNA-activated, catalytic polypeptide" -- Nucleus kinase PSEN1 presenilin 1 -- Plasma Membrane peptidase PTGER3 prostaglandin E receptor 3 (subtype EP3) -- Plasma Membrane G-protein coupled receptor PTPN6 " protein tyrosine phosphatase, non-receptor type 6" -- Cytoplasm phosphatase PTPRJ " protein tyrosine phosphatase, receptor type, J" -- Plasma Membrane phosphatase RAC1 " ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" -- Cytoplasm enzyme RAD23B RAD23 homolog B (S. cerevisiae) -- Nucleus other RAD51 " RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)" -- Nucleus enzyme RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) -- Cytoplasm enzyme RAMP2 receptor (G protein-coupled) activity modifying protein 2 -- Plasma Membrane other RARA " retinoic acid receptor, alpha" -- Nucleus ligand-dependent nuclear receptor RASA1 RAS p21 protein activator (GTPase activating protein) 1 -- Cytoplasm transporter RB1 retinoblastoma 1 -- Nucleus transcription regulator RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -- Cytoplasm enzyme RET ret proto-oncogene -- Plasma Membrane kinase RPSA ribosomal protein SA -- Plasma Membrane transmembrane receptor RXRA " retinoid X receptor, alpha" -- Nucleus ligand-dependent nuclear receptor SCD stearoyl-CoA desaturase (delta-9-desaturase) -- Cytoplasm enzyme SIRPA signal-regulatory protein alpha -- Plasma Membrane phosphatase SLC25A10 " solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10" -- Cytoplasm transporter SLC26A2 " solute carrier family 26 (sulfate transporter), member 2" -- Plasma Membrane transporter SMARCA4 " SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" -- Nucleus transcription regulator SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -- Nucleus other SOX4 SRY (sex determining region Y)-box 4 -- Nucleus transcription regulator SPTLC1 " serine palmitoyltransferase, long chain base subunit 1" -- Cytoplasm enzyme SREBF1 sterol regulatory element binding transcription factor 1 -- Nucleus transcription regulator SRF serum response factor (c-fos serum response element-binding transcription factor) -- Nucleus transcription regulator SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) -- Nucleus enzyme SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -- Nucleus transcription regulator SUZ12 suppressor of zeste 12 homolog (Drosophila) -- Nucleus enzyme TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -- Nucleus transcription regulator TBP TATA box binding protein -- Nucleus transcription regulator TCF7L2 " transcription factor 7-like 2 (T-cell specific, HMG-box)" -- Nucleus transcription regulator TCL1A T-cell leukemia/lymphoma 1A -- Nucleus other TFDP1 transcription factor Dp-1 -- Nucleus transcription regulator TGFA " transforming growth factor, alpha" -- Extracellular Space growth factor TGIF1 TGFB-induced factor homeobox 1 -- Nucleus transcription regulator TNF " tumor necrosis factor (TNF superfamily, member 2)" -- Extracellular Space cytokine TNFAIP2 " tumor necrosis factor, alpha-induced protein 2" -- Extracellular Space other TNFRSF12A " tumor necrosis factor receptor superfamily, member 12A" -- Plasma Membrane other TP53 tumor protein p53 -- Nucleus transcription regulator TRIM24 tripartite motif-containing 24 -- Nucleus transcription regulator TSC22D1 " TSC22 domain family, member 1" -- Nucleus transcription regulator USP24 ubiquitin specific peptidase 24 -- Unknown peptidase USP25 ubiquitin specific peptidase 25 -- Unknown peptidase USP9X " ubiquitin specific peptidase 9, X-linked" -- Plasma Membrane peptidase VAV1 vav 1 guanine nucleotide exchange factor -- Nucleus transcription regulator VCAM1 vascular cell adhesion molecule 1 -- Plasma Membrane other VHL von Hippel-Lindau tumor suppressor -- Nucleus other WISP2 WNT1 inducible signaling pathway protein 2 -- Extracellular Space growth factor XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -- Nucleus enzyme XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -- Nucleus enzyme YBX2 Y box binding protein 2 -- Cytoplasm translation regulator YEATS4 YEATS domain containing 4 -- Nucleus transcription regulator YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 -- Cytoplasm kinase ZHX2 zinc fingers and homeoboxes 2 -- Nucleus transcription regulator ZNF217 zinc finger protein 217 -- Nucleus transcription regulator