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{\title Template - Research Article - General}{\subject Template for research manuscripts}{\author Emma Veitch}{\operator nicole}{\creatim\yr2008\mo5\dy18\hr21\min43}{\revtim\yr2008\mo5\dy18\hr22\min8}{\version8}{\edmins23}{\nofpages4}{\nofwords999}
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Extent of mucosal damage created by custom-defined magnitude\cell \hich\af0\dbch\af13\loch\f0 Initial damage = Magnitude * Magnitude + a normally distributed random number with mean = 0 and standard deviation = 1000\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow1\irowband1\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow2\irowband2\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Extent of mucosal damage induced by TNF-}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \hich\af0\dbch\af13\loch\f0 If TNF-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 >0.1, damage + 1\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow3\irowband3\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow4\irowband4\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Effect of the 4-hr resonant voice exercise on mucosa\cell \hich\af0\dbch\af13\loch\f0 If the time step is between 1 and 3, create a damage = 10 + a normally distributed random number with mean = 0 and standard deviation = 10\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow5\irowband5\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow6\irowband6\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Effect of the 4-hr spontaneous speech on mucosa
\cell \hich\af0\dbch\af13\loch\f0 If the time step is between 1 and 3, create a damage = 30 + a normally distributed random number with mean = 0 and standard deviation = 10\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow7\irowband7\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow8\irowband8\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  secreted by platelets\cell \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol"
 \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + number of platelet/10\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow9\irowband9\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow10\irowband10\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Platelet diffusion coefficient\cell 
\hich\af0\dbch\af13\loch\f0 Platelet = 1 unit/step\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow11\irowband11\ltrrow
\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow12\irowband12\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Inflammatory mediator diffusion speed \cell 
\hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 = 1 unit/step
\par \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 = 1 unit/step
\par \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = 1 unit/step
\par \hich\af0\dbch\af13\loch\f0 IL-10 = 1 unit/step\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow13\irowband13\ltrrow
\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow14\irowband14\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Collagen diffusion coefficient\cell 
\hich\af0\dbch\af13\loch\f0 0.5 unit/step\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow15\irowband15\ltrrow
\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow16\irowband16\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Inflammatory mediator degradation speed\cell 
\hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 = 0.2 unit/step
\par \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 = 0.2 unit/step
\par \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = 0.2 unit/step
\par \hich\af0\dbch\af13\loch\f0 IL-10 = 0.25 unit/step\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow17\irowband17\ltrrow
\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow18\irowband18\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Collagen degradation coefficient\cell 
\hich\af0\dbch\af13\loch\f0 0.99 unit/step\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow19\irowband19\ltrrow
\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow20\irowband20\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16461299 \hich\af0\dbch\af13\loch\f0 Collagen repairs}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 tissue }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 damage\cell 
\hich\af0\dbch\af13\loch\f0 If collagen>1, the damaged tissue that \hich\af0\dbch\af13\loch\f0 underne\hich\af0\dbch\af13\loch\f0 ath }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16461299 \hich\af0\dbch\af13\loch\f0 is repaired}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14185899 \hich\af0\dbch\af13\loch\f0  by }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 the collagen.\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow21\irowband21\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow22\irowband22\ltrrow\ts11\trgaph108\trleft-108\trbrdrt\brdrs\brdrw10 \trbrdrb\brdrs\brdrw10 
\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkborder\tbllkshading\tbllkfont\tbllkcolor\tbllkbestfit\tbllkhdrrows\tbllkhdrcols\tblind0\tblindtype3 \clvertalt\clbrdrt
\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrtbl \clbrdrb\brdrnone \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\trowd \irow23\irowband23\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Initial number of neutrophils\cell \hich\af0\dbch\af13\loch\f0 60\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow23\irowband23\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow24\irowband24\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Number of neutrophils recruited relating to }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 tissue }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 damage\cell \hich\af0\dbch\af13\loch\f0 2 * (damage / magnitude}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\super\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 2}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  ) + 1\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow25\irowband25\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow26\irowband26\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429\charrsid4591706 \trowd \irow27\irowband27\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Platelets chemoattract neutrophils \cell 
\hich\af0\dbch\af13\loch\f0 If platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 >platelet}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 >platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 left, 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 t\hich\af0\dbch\af13\loch\f0 he }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 neutrophil\hich\af0\dbch\af13\loch\f0  turns 90}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  right. 
\par \hich\af0\dbch\af13\loch\f0 If platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 >platelet}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 the n}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 eutrophil turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  left. \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow28\irowband28\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow29\irowband29\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  chemoattracts neutrophils\cell \hich\af0\dbch\af13\loch\f0 
If TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMB
OL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TNF-}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left, }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0 t\hich\af0\dbch\af13\loch\f0 he }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 neutrophil turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  right. }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid2756603 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 If TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
{\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0 the n}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 eutrophil turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  left. \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow30\irowband30\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 TGF\hich\af0\dbch\af13\loch\f0 -}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 
\hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  chemoattracts neutrophils\cell \hich\af0\dbch\af13\loch\f0 If TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
{\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
and TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL
 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left, }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14185899 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 neutrophil turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL
 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  right. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid14185899 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 If TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-}
{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 the n}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
eutrophil turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  left. \cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow31\irowband31\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow32\irowband32\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  chemoattracts neutrophils\cell \hich\af0\dbch\af13\loch\f0 
If IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMB
OL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > IL-1}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left, }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 th\hich\af0\dbch\af13\loch\f0 e }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 neutrophil turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  right. }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid8343429 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 If IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
{\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 the n}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 eutrophil turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  left. \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow33\irowband33\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow34\irowband34\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Area of mucosal damage that activates neutrophils\cell 
\hich\af0\dbch\af13\loch\f0 If }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 neutrophil migrat\hich\af0\dbch\af13\loch\f0 
es to the area that has the damage greater than (magnitude + total-damage * 2), }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
neutrophil is activated}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow35\irowband35\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow36\irowband36\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 (and IL-10)  stimulates (and inhibits) activation of neutrophils\cell \hich\af0\dbch\af13\loch\f0 If TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  - (IL-10 *\hich\af0\dbch\af13\loch\f0  5000) > 0.1, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 neutrophil is activated}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow37\irowband37\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow38\irowband38\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  secreted by activated neutrophil\cell 
\hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 =  TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0   + (0.1 * ( 1 / (TGF-}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  * 0.5 +  IL-10 * 5) )\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\strike\insrsid9127220\charrsid4591706 \trowd \irow39\irowband39\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow40\irowband40\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0 N}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 eutrophil lifespan\cell \hich\af0\dbch\af13\loch\f0 2 to 4 days\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \trowd \irow41\irowband41\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow42\irowband42\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 IL-10 inhibits activated neutrophil survival\cell 
\hich\af0\dbch\af13\loch\f0 If total-IL-10 > 1, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 neutrophil age \hich\f0 \endash 
\loch\f0  0.5\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow43\irowband43\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\trowd \irow44\irowband44\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil 
\cellx8748\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow44\irowband44\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrtbl 
\clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\trowd \irow45\irowband45\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Initial number of residential macrophages \cell \hich\af0\dbch\af13\loch\f0 120\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow45\irowband45\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow46\irowband46\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Magnitude of damage to recruit resting macrophage \cell 
\hich\af0\dbch\af13\loch\f0 If damage > magnitude * 1.2, resting macrophage will be recruited}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow47\irowband47\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow48\irowband48\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Number of macrophages recruited  relating to damage\cell 
\hich\af0\dbch\af13\loch\f0 4 * damage / magnitude}{\rtlch\fcs1 \af0 \ltrch\fcs0 \super\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 2  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 +  1\cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow49\irowband49\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow50\irowband50\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Platelets chemoattract macrophages\cell 
\hich\af0\dbch\af13\loch\f0 If platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 >platelet}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 >platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 left, 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0 t}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 he }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
macrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  right. 

\par \hich\af0\dbch\af13\loch\f0 If platelet}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 >platelet}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid8343429 \hich\af0\dbch\af13\loch\f0  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 the m}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 acrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  left. \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow51\irowband51\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 chemoattracts macrophages\cell \hich\af0\dbch\af13\loch\f0 If TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL
 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and TNF-}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left, 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 t\hich\af0\dbch\af13\loch\f0 he }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 macrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  right. 
\par \hich\af0\dbch\af13\loch\f0 If TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt
\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8343429 \hich\af0\dbch\af13\loch\f0 the m}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 acrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  left. \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow52\irowband52\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow53\irowband53\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  chemoattracts macrophages\cell \hich\af0\dbch\af13\loch\f0 If TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-
}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMB
OL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 
\hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 macrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  right. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid14185899 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 If TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-}
{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 the m}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
acrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  left. \cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow54\irowband54\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow55\irowband55\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  chemoattracts macrophages\cell \hich\af0\dbch\af13\loch\f0 
If IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMB
OL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > IL-1}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left,}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \sub\insrsid14185899 \hich\af0\dbch\af13\loch\f0  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 t\hich\af0\dbch\af13\loch\f0 he }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 macrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  right. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid14185899 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 If IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
{\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid14185899 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 the m}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 acrophage turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  left. \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow56\irowband56\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\trowd \irow57\irowband57\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrtbl 
\clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow57\irowband57\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrtbl 
\clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\trowd \irow58\irowband58\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Area of mucosal damage that activates macrophages\cell \hich\af0\dbch\af13\loch\f0 If }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
macrophage migrates to the area that has the damage greater than (magnitude + total-damage) * 0.01, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 macrophage is activated}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow58\irowband58\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow59\irowband59\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ,TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  (and IL-10) stimulates (and inhibits) activation of mac
\hich\af0\dbch\af13\loch\f0 rophages\cell \hich\af0\dbch\af13\loch\f0 If IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  - IL-10 > 400, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
macrophage is activated}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow60\irowband60\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow61\irowband61\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Inflammatory mediators secreted by activated macrophages under voice rest condition\cell }{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TNF-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 + 0.1 * (1 / (1 + TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899\charrsid14185899 
\hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + total-IL-10)) * (1 + total-TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
{\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 + total-IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14185899\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899 \hich\af0\dbch\af13\loch\f0  +40}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 )
\par \hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + 1 * (1 / (1 \hich\af0\dbch\af13\loch\f0 + TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbo
l" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899\charrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  + total-IL-10)) * (1 + total-TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  * 30 + total-IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + 40)
\par \hich\af0\dbch\af13\loch\f0 IL-10 = IL-10 + 2 + (total-IL-10 * 0.001)
\par \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + (1+ total-I\hich\af0\dbch\af13\loch\f0 
L-10 + total-TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 )\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 
\trowd \irow62\irowband62\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \trowd \irow63\irowband63\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Inflammatory mediators secreted by activated macrophages under resonant voice condition\cell }{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TNF-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + 0.1 * (1 / (1 + 
\hich\af0\dbch\af13\loch\f0 TGF\hich\af0\dbch\af13\loch\f0 -}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid14185899\charrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + total-IL-10)) * (1 + total-TNF-}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
+ total-IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  * 0.5 +40 )
\par \hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + 1 * (1 / (1+ TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}
{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899\charrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 + total-IL-10)) * (1 + total-TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  * 10 + total-IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + 40)
\par \hich\af0\dbch\af13\loch\f0 IL-10 = IL-10 + 1 + (total-IL-10 * 0.01)
\par \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + (1+ total-IL-10 + total-TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt
\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 )\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 
\af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \trowd \irow64\irowband64\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \trowd \irow65\irowband65\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Inflammatory mediators secreted by activated macrophages under spontaneous speech condition\cell }{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TNF-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 + 0.1 * (1 / (1 + TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899\charrsid14185899 
\hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + total-IL-10)) * (1 + \hich\af0\dbch\af13\loch\f0 total-TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 + total-IL-1}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid14185899\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  * 0.5 +40)
\par \hich\af0\dbch\af13\loch\f0 IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + 1 * (1 / (1+ TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}
{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899\charrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 * 0.8 + total-IL-10)) * (1 + total-TNF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  * 50 + total-IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + 40)
\par \hich\af0\dbch\af13\loch\f0 IL-10 = IL-10 + 1.5 + (total-IL-10 * 0.001)
\par \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  + (1+ total-IL-10 + total-TNF-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 )\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \trowd \irow66\irowband66\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \trowd \irow67\irowband67\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Tim}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 
\hich\af0\dbch\af13\loch\f0 e period that macrophages }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11471449 \hich\af0\dbch\af13\loch\f0 may }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 kill}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  neutrophils\cell \hich\af0\dbch\af13\loch\f0 During 3.8-4.8 day post-jury\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow68\irowband68\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Probability of macrophages killing neutrophils\cell 
\hich\af0\dbch\af13\loch\f0 90% chance after 4-5 post-damage days\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow69\irowband69\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow70\irowband70\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Macrophage lifespan\cell \hich\af0\dbch\af13\loch\f0 5-9 days
\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow71\irowband71\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid4591706 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid9127220\charrsid4591706 \trowd \irow72\irowband72\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Initial number of residential fibroblasts\cell 
\hich\af0\dbch\af13\loch\f0 250\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow73\irowband73\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow74\irowband74\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Magnitude of damage to recruit tissue fibroblasts \cell 
\hich\af0\dbch\af13\loch\f0 If damage > magnitude * 1.2, tissue fibroblasts will be recruited.\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \trowd \irow75\irowband75\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow76\irowband76\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Number of tissue fibroblasts being recruited related to damage
\cell \hich\af0\dbch\af13\loch\f0 4 * damage / magnitude}{\rtlch\fcs1 \af0 \ltrch\fcs0 \super\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 2  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 +  1
\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow77\irowband77\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow78\irowband78\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  ch\hich\af0\dbch\af13\loch\f0 emoattracts tissue fibroblasts\cell \hich\af0\dbch\af13\loch\f0 If TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt
\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 > TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 ahead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 and TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
{\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the
\hich\af0\dbch\af13\loch\f0  \hich\af0\dbch\af13\loch\f0 t}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\delrsid9397400\charrsid4591706 \hich\af0\dbch\af13\loch\f0 issue }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0 fibroblast turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  right. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid135524 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 If TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 left}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 > TGF-}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\sub\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 right, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\delrsid9397400\charrsid4591706 \hich\af0\dbch\af13\loch\f0 t}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 
he t}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 issue fibroblast turns 90}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 176 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  left. \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \trowd \irow79\irowband79\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow80\irowband80\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\delrsid9397400\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Tissue }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 fibroblasts differentiate to activated fibroblasts\cell \hich\af0\dbch\af13\loch\f0 If }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 tissue fibroblast migrates to t\hich\af0\dbch\af13\loch\f0 he area that has the damage greater than TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
{\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11471449 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  > 0.1, }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the \hich\af0\dbch\af13\loch\f0 tissue fibroblast}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  differentiate}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 s}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  to activated fibroblast.\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow81\irowband81\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow82\irowband82\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Proliferation of activated fibroblasts\cell 
\hich\af0\dbch\af13\loch\f0 If }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 activated fibroblast ages 3-13 days, }{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid135524 \hich\af0\dbch\af13\loch\f0 the }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 fibroblast proliferates}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 .
}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow83\irowband83\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell 
}\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow84\irowband84\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11471449 \hich\af0\dbch\af13\loch\f0 Fibroblast}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11471449 \hich\af0\dbch\af13\loch\f0 p\hich\af0\dbch\af13\loch\f0 roliferation}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 are stimulated by IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 , TNF-}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 97 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  and TGF-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\cell \hich\af0\dbch\af13\loch\f0 1 + 0.001 * (total-TGF}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899\charrsid10359331 \hich\af0\dbch\af13\loch\f0 -}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899\charrsid4591706 
{\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
 * 0.5 + total-TNF * 0.5 + total-IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  * 0.5)\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow85\irowband85\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow86\irowband86\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Inflammatory mediators secreted by activated fibroblasts\cell }
{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid10359331 \hich\af0\dbch\af13\loch\f0 TNF-}{\rtlch\fcs1 \af280 \ltrch\fcs0 \f280\insrsid9127220\charrsid4591706 \loch\af280\dbch\af13\hich\f280 \'e1}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid10359331 \hich\af0\dbch\af13\loch\f0  = TNF-}{\rtlch\fcs1 \af280 \ltrch\fcs0 \f280\insrsid9127220\charrsid4591706 \loch\af280\dbch\af13\hich\f280 \'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid2756603 \hich\af0\dbch\af13\loch\f0  + 0.2 * (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid10359331 \hich\af0\dbch\af13\loch\f0 1 / (1 + total-TGF-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid10359331 \hich\af0\dbch\af13\loch\f0  + total-IL-10))
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  = TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Sy
mbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2756603 \hich\af0\dbch\af13\loch\f0  + (}{\rtlch\fcs1 \af280 \ltrch\fcs0 
\f280\insrsid9127220\charrsid4591706 \hich\af280\dbch\af13\loch\f280 \hich\f280 1 + total-TNF-\'e1\loch\f280  * 0.5 + total-IL-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 10 * 0.5 )\cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow87\irowband87\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \trowd \irow88\irowband88\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow}\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Collagen secreted by activated fibroblasts\cell }{\rtlch\fcs1 
\af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 Collagen = Collagen + 2 * (1 + total-TGF-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol"
 \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid14185899\charrsid14185899 \hich\af0\dbch\af13\loch\f0 1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 
\hich\af0\dbch\af13\loch\f0  * 2) / (1 + total-IL-1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 {\field{\*\fldinst SYMBOL 98 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0  * 0.5)\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \trowd \irow89\irowband89\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone 
\clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\trowd \irow90\irowband90\ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil 
\cellx8748\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \cell \cell }\pard \ltrpar
\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1036\langfe1033\langnp1036\insrsid9127220\charrsid4591706 \trowd \irow90\irowband90\ltrrow
\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrtbl 
\clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrtbl \clbrdrl\brdrtbl \clbrdrb\brdrtbl \clbrdrr\brdrtbl \cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row \ltrrow
}\trowd \irow91\irowband91\lastrow \ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrtbl \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrtbl \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid9127220 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 \hich\af0\dbch\af13\loch\f0 
Fibroblast lifespan\cell \hich\af0\dbch\af13\loch\f0 3-5 days\cell }\pard \ltrpar\ql \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid4591706 
\trowd \irow91\irowband91\lastrow \ltrrow\ts11\trgaph108\trleft-108\trftsWidth1\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblrsid4591706\tbllkhdrrows\tbllklastrow\tbllkhdrcols\tbllklastcol
\tblind0\tblindtype3 \clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrtbl \clbrdrr\brdrnone \cltxlrtb\clftsWidth1\clshdrawnil \cellx3385\clvertalt\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrtbl \clbrdrr\brdrnone 
\cltxlrtb\clftsWidth1\clshdrawnil \cellx8748\row }\pard\plain \ltrpar\s31\ql \li0\ri0\sl360\slmult1\nowidctlpar\tqc\tx4320\tqr\tx8640\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid9127220 \rtlch\fcs1 \af0\afs20\alang1025 
\ltrch\fcs0 \fs24\lang1033\langfe1041\kerning2\loch\af39\hich\af39\dbch\af13\cgrid\langnp1033\langfenp1041 {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1024\langfe1024\noproof\langfenp1028\insrsid11471449 
{\shpgrp{\*\shpinst\shpleft480\shptop491\shpright10440\shpbottom2691\shpfhdr0\shpbxcolumn\shpbxignore\shpbypara\shpbyignore\shpwr3\shpwrk0\shpfblwtxt0\shpz0\shplid1026
{\sp{\sn groupLeft}{\sv 1080}}{\sp{\sn groupTop}{\sv 6640}}{\sp{\sn groupRight}{\sv 11040}}{\sp{\sn groupBottom}{\sv 8840}}{\sp{\sn fFlipH}{\sv 0}}{\sp{\sn fFlipV}{\sv 0}}{\sp{\sn fLockRotation}{\sv 0}}{\sp{\sn fLockAspectRatio}{\sv 1}}
{\sp{\sn fLockPosition}{\sv 0}}{\sp{\sn lidRegroup}{\sv 0}}{\sp{\sn posh}{\sv 0}}{\sp{\sn posrelh}{\sv 3}}{\sp{\sn posv}{\sv 0}}{\sp{\sn posrelv}{\sv 3}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fAllowOverlap}{\sv 1}}{\sp{\sn fBehindDocument}{\sv 0}}
{\sp{\sn dgmt}{\sv 0}}{\sp{\sn fPseudoInline}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shp{\*\shpinst\shplid1027{\sp{\sn relLeft}{\sv 1080}}{\sp{\sn relTop}{\sv 6640}}{\sp{\sn relRight}{\sv 11040}}
{\sp{\sn relBottom}{\sv 8840}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 75}}{\sp{\sn fLockText}{\sv 1}}{\sp{\sn cxk}{\sv 0}}{\sp{\sn fShadowOK}{\sv 1}}{\sp{\sn f3DOK}{\sv 1}}{\sp{\sn fLineOK}{\sv 1}}
{\sp{\sn fFillOK}{\sv 1}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn fNoFillHitTest}{\sv 1}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fPreferRelativeResize}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}}{\shprslt{\*\do\dobxcolumn\dobypara\dodhgt8192
\dpgroup\dpcount2\dpx480\dpy491\dpxsize9960\dpysize2200\dppolygon\dppolycount4\dpptx0\dppty0\dpptx0\dppty2200\dpptx9960\dppty2200\dpptx9960\dppty0\dpx0\dpy0\dpxsize9960\dpysize2200
\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat0\dplinehollow\dpendgroup\dpx0\dpy0\dpxsize0\dpysize0}}}}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\insrsid9127220\charrsid5330707 
\par }\pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid9127220 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1033\langfe1033\loch\af0\hich\af0\dbch\af13\cgrid\langnp1033\langfenp1033 {
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid5330707 
\par }\pard \ltrpar\ql \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid2103953 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9127220\charrsid12723961 
\par }}