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Research Article

Anti-Platelet Therapy with Clopidogrel Prevents Endothelial Dysfunction and Vascular Remodeling in Aortas from Hypertensive Rats

  • Fernanda R. Giachini mail,

    fernandagiachini@hotmail.com

    Affiliation: Institute of Biological Sciences and Health, Federal University of Mato Grosso, Barra do Garças, MT, Brazil

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  • Romulo Leite,

    Affiliation: School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, MG, Brazil

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  • David A. Osmond,

    Affiliation: Department of Physiology, Georgia Regents University, Augusta, Georgia, United States of America

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  • Victor V. Lima,

    Affiliation: Institute of Biological Sciences and Health, Federal University of Mato Grosso, Barra do Garças, MT, Brazil

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  • Edward W. Inscho,

    Affiliation: Department of Physiology, Georgia Regents University, Augusta, Georgia, United States of America

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  • R. Clinton Webb,

    Affiliation: Department of Physiology, Georgia Regents University, Augusta, Georgia, United States of America

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  • Rita C. Tostes

    Affiliation: Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, SP, Brazil

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  • Published: March 17, 2014
  • DOI: 10.1371/journal.pone.0091890

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