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Open Access
Peer-reviewed
Research Article
Rule-Based Models of the Interplay between Genetic and Environmental Factors in Childhood Allergy
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Susanne Bornelöv ,
Contributed equally to this work with: Susanne Bornelöv, Annika Sääf
Affiliation Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden
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Annika Sääf ,
Contributed equally to this work with: Susanne Bornelöv, Annika Sääf
Affiliation Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Erik Melén,
Affiliations Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Sachs' Children's Hospital, South General Hospital, Stockholm, Sweden
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Anna Bergström,
Affiliation Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Behrooz Torabi Moghadam,
Affiliation Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden
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Ville Pulkkinen,
Affiliation Research Programs Unit, Biomedicum, University of Helsinki and Folkhälsan Institute of Genetics, Helsinki, Finland
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Nathalie Acevedo,
Affiliations Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, Department of Medicine Solna, Translational Immunology Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden
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Christina Orsmark Pietras,
Affiliation Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
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Markus Ege,
Affiliation Dr von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany
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Charlotte Braun-Fahrländer,
Affiliations Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, Department of Public Health, University of Basel, Basel, Switzerland
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Josef Riedler,
Affiliation Department of Children and Young Adults' Medicine, Kardinal Schwarzenberg Hospital, Schwarzach, Austria
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Gert Doekes,
Affiliation Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
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Michael Kabesch,
Affiliation Department of Pediatric Pneumology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany
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Marianne van Hage,
Affiliation Clinical Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden
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Juha Kere,
Affiliations Research Programs Unit, Biomedicum, University of Helsinki and Folkhälsan Institute of Genetics, Helsinki, Finland, Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
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Annika Scheynius,
Affiliation Department of Medicine Solna, Translational Immunology Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden
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Cilla Söderhäll,
Affiliation Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
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Göran Pershagen ,
* E-mail: goran.pershagen@ki.se
¶Jointly directed the work.
Affiliation Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Jan Komorowski
¶Jointly directed the work.
Affiliations Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden, Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw, Warsaw, Poland
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Rule-Based Models of the Interplay between Genetic and Environmental Factors in Childhood Allergy
- Susanne Bornelöv,
- Annika Sääf,
- Erik Melén,
- Anna Bergström,
- Behrooz Torabi Moghadam,
- Ville Pulkkinen,
- Nathalie Acevedo,
- Christina Orsmark Pietras,
- Markus Ege,
- Charlotte Braun-Fahrländer
- Published: November 19, 2013
- https://doi.org/10.1371/journal.pone.0080080