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Research Article

The Relative Timing of Mutations in a Breast Cancer Genome

  • Scott Newman,

    Affiliation: Hutchison/MRC Research Centre and Department of Pathology, University of Cambridge, Cambridge, United Kingdom

    Current address: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Karen D. Howarth,

    Affiliation: Hutchison/MRC Research Centre and Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Chris D. Greenman,

    Affiliation: Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom

    Current address: The Genome Analysis Centre, Norwich Research Park, Norwich, United Kingdom

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  • Graham R. Bignell,

    Affiliation: Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom

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  • Simon Tavaré,

    Affiliation: CRUK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom

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  • Paul A. W. Edwards mail

    pawe1@cam.ac.uk

    Affiliation: Hutchison/MRC Research Centre and Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Published: June 10, 2013
  • DOI: 10.1371/journal.pone.0064991

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