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Research Article

IL-13 Promotes Collagen Accumulation in Crohn’s Disease Fibrosis by Down-Regulation of Fibroblast MMP Synthesis: A Role for Innate Lymphoid Cells?

  • Jennifer R. Bailey,

    Affiliation: School of Veterinary Science, University of Bristol, Bristol, United Kingdom

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  • Paul W. Bland equal contributor,

    equal contributor Contributed equally to this work with: Paul W. Bland, John F. Tarlton

    Affiliations: School of Veterinary Science, University of Bristol, Bristol, United Kingdom, Mucosal Immunobiology and Vaccine Center (MIVAC), Department of Microbiology and Immunology, University of Gothenburg, Gothenburg, Sweden

    X
  • John F. Tarlton equal contributor mail,

    equal contributor Contributed equally to this work with: Paul W. Bland, John F. Tarlton

    John.Tarlton@bris.ac.uk

    Affiliation: School of Veterinary Science, University of Bristol, Bristol, United Kingdom

    X
  • Iain Peters,

    Affiliation: Molecular Testing, Innovation Centre, University of Exeter, Exeter, United Kingdom

    X
  • Moganaden Moorghen,

    Affiliation: Histopathology Department, St Mark’s Hospital, Harrow, United Kingdom

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  • Paul A. Sylvester,

    Affiliation: Department of Surgery, Bristol Royal Infirmary, Bristol, United Kingdom

    X
  • Christopher S. J. Probert,

    Affiliation: Department of Gastroenterology, University of Liverpool, Liverpool, United Kingdom

    X
  • Christine V. Whiting

    Affiliation: School of Veterinary Science, University of Bristol, Bristol, United Kingdom

    X
  • Published: December 31, 2012
  • DOI: 10.1371/journal.pone.0052332

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