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Research Article

A Host Transcriptional Signature for Presymptomatic Detection of Infection in Humans Exposed to Influenza H1N1 or H3N2

  • Christopher W. Woods equal contributor mail,

    equal contributor Contributed equally to this work with: Christopher W. Woods, Micah T. McClain

    chris.woods@duke.edu (CW); geoffrey.ginsburg@duke.edu (GG)

    Affiliations: Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America, Durham Veteran’s Affairs Medical Center, Durham, North Carolina, United States of America

    X
  • Micah T. McClain equal contributor,

    equal contributor Contributed equally to this work with: Christopher W. Woods, Micah T. McClain

    Affiliations: Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America, Durham Veteran’s Affairs Medical Center, Durham, North Carolina, United States of America

    X
  • Minhua Chen,

    Affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina, United States of America

    X
  • Aimee K. Zaas,

    Affiliations: Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Bradly P. Nicholson,

    Affiliation: Durham Veteran’s Affairs Medical Center, Durham, North Carolina, United States of America

    X
  • Jay Varkey,

    Affiliation: Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Timothy Veldman,

    Affiliation: Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Stephen F. Kingsmore,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Yongsheng Huang,

    Affiliation: Center for Computational Biology and Bioinformatics, University of Michigan, Ann Arobor, Michigan, United States of America

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  • Robert Lambkin-Williams,

    Affiliation: Retroscreen Virology, London, United Kingdom

    X
  • Anthony G. Gilbert,

    Affiliation: Retroscreen Virology, London, United Kingdom

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  • Alfred O. Hero III,

    Affiliation: Center for Computational Biology and Bioinformatics, University of Michigan, Ann Arobor, Michigan, United States of America

    X
  • Elizabeth Ramsburg,

    Affiliation: Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Seth Glickman,

    Affiliation: Department of Emergency Medicine, University of North Carolina-Chapel-Hill, Chapel Hill, North Carolina, United States of America

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  • Joseph E. Lucas,

    Affiliation: Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Lawrence Carin,

    Affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina, United States of America

    X
  • Geoffrey S. Ginsburg mail

    chris.woods@duke.edu (CW); geoffrey.ginsburg@duke.edu (GG)

    Affiliation: Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Published: January 09, 2013
  • DOI: 10.1371/journal.pone.0052198

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