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Research Article

Sensitivity to Lysosome-Dependent Cell Death Is Directly Regulated by Lysosomal Cholesterol Content

  • Hanna Appelqvist mail,

    hanna.appelqvist@liu.se

    Affiliation: Experimental Pathology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden

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  • Linnea Sandin,

    Affiliation: Experimental Pathology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden

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  • Karin Björnström,

    Affiliations: Anaesthesiology, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden, Department of Anaesthesiology UHL, County Council of Östergötland, Linköping, Sweden

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  • Paul Saftig,

    Affiliation: Biochemical Institute, Christian-Albrechts-University Kiel, Kiel, Germany

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  • Brett Garner,

    Affiliations: Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, Australia, School of Biological Sciences, University of Wollongong, Wollongong, Australia

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  • Karin Öllinger,

    Affiliations: Experimental Pathology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden, Department of Clinical Pathology and Clinical Genetics, County Council of Östergötland, Linköping, Sweden

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  • Katarina Kågedal

    Affiliation: Experimental Pathology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden

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  • Published: November 16, 2012
  • DOI: 10.1371/journal.pone.0050262

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