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Research Article

Induction of Tumor Cell Death through Targeting Tubulin and Evoking Dysregulation of Cell Cycle Regulatory Proteins by Multifunctional Cinnamaldehydes

  • Amrita A. Nagle,

    Affiliation: Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore

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  • Fei-Fei Gan,

    Affiliation: Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore

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  • Gavin Jones,

    Affiliation: Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, London, United Kingdom

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  • Choon-Leng So,

    Affiliation: Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore

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  • Geoffrey Wells,

    Affiliation: Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, London, United Kingdom

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  • Eng-Hui Chew mail

    phaceh@nus.edu.sg

    Affiliation: Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore

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  • Published: November 21, 2012
  • DOI: 10.1371/journal.pone.0050125

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