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Research Article

Transfusion of CXCR4-Primed Endothelial Progenitor Cells Reduces Cerebral Ischemic Damage and Promotes Repair in db/db Diabetic Mice

  • Ji Chen equal contributor,

    equal contributor Contributed equally to this work with: Ji Chen, Jianying Chen, Shuzhen Chen

    Affiliations: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

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  • Jianying Chen equal contributor,

    equal contributor Contributed equally to this work with: Ji Chen, Jianying Chen, Shuzhen Chen

    Affiliation: Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

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  • Shuzhen Chen equal contributor,

    equal contributor Contributed equally to this work with: Ji Chen, Jianying Chen, Shuzhen Chen

    Affiliation: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

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  • Cheng Zhang,

    Affiliation: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

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  • Liangqing Zhang,

    Affiliation: Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

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  • Xiang Xiao,

    Affiliation: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

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  • Avik Das,

    Affiliation: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

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  • Yuhui Zhao,

    Affiliations: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China

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  • Bin Yuan,

    Affiliations: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

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  • Mariana Morris,

    Affiliation: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

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  • Bin Zhao ,

    Affiliation: Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

    These authors also contributed equally to this work.

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  • Yanfang Chen mail

    yanfang.chen@wright.edu

    Affiliations: Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

    These authors also contributed equally to this work.

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  • Published: November 21, 2012
  • DOI: 10.1371/journal.pone.0050105

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