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Research Article

The Plant-Derived Glucocorticoid Receptor Agonist Endiandrin A Acts as Co-Stimulator of Colonic Epithelial Sodium Channels (ENaC) via SGK-1 and MAPKs

  • Dana Kuntzsch,

    Affiliation: Department of Gastroenterology, Division of Nutritional Medicine, Charité, Campus Benjamin Franklin, Berlin, Germany

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  • Theresa Bergann,

    Affiliation: Department of Gastroenterology, Division of Nutritional Medicine, Charité, Campus Benjamin Franklin, Berlin, Germany

    Current address: Institute of Biochemistry, Charité, Campus Virchow Klinikum, Berlin, Germany

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  • Petra Dames,

    Affiliation: Department of Gastroenterology, Division of Nutritional Medicine, Charité, Campus Benjamin Franklin, Berlin, Germany

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  • Anja Fromm,

    Affiliation: Institute of Clinical Physiology, Charité, Campus Benjamin Franklin, Berlin, Germany

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  • Michael Fromm,

    Affiliation: Institute of Clinical Physiology, Charité, Campus Benjamin Franklin, Berlin, Germany

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  • Rohan A. Davis,

    Affiliation: Eskitis Institute, Griffith University, Brisbane, Queensland, Australia

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  • Matthias F. Melzig,

    Affiliation: Institute of Pharmacy, Pharmaceutical Biology, Freie Universität Berlin, Berlin, Germany

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  • Joerg D. Schulzke mail

    joerg.schulzke@charite.de

    Affiliation: Department of Gastroenterology, Division of Nutritional Medicine, Charité, Campus Benjamin Franklin, Berlin, Germany

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  • Published: November 13, 2012
  • DOI: 10.1371/journal.pone.0049426

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