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Research Article

Transcutaneous Application of Carbon Dioxide (CO2) Induces Mitochondrial Apoptosis in Human Malignant Fibrous Histiocytoma In Vivo

  • Yasuo Onishi,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Teruya Kawamoto mail,

    trykwmt@med.kobe-u.ac.jp

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Takeshi Ueha,

    Affiliation: NeoChemir Inc., Gokodori, Chuo-ku, Kobe, Hyogo, Japan

    X
  • Kenta Kishimoto,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Hitomi Hara,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Naomasa Fukase,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Mitsunori Toda,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Risa Harada,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Masaya Minoda,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Yoshitada Sakai,

    Affiliation: Faculty of Health Care Sciences, Himeji Dokkyo University, Kami-Ohno, Himeji, Hyogo, Japan

    X
  • Masahiko Miwa,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Masahiro Kurosaka,

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Toshihiro Akisue

    Affiliation: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kusunoki-cho, Chuo-ku, Kobe, Japan

    X
  • Published: November 15, 2012
  • DOI: 10.1371/journal.pone.0049189

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