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Research Article

Prostatic Acid Phosphatase Is Required for the Antinociceptive Effects of Thiamine and Benfotiamine

  • Julie K. Hurt,

    Affiliation: Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

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  • Jennifer L. Coleman,

    Affiliation: Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

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  • Brendan J. Fitzpatrick,

    Affiliation: Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

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  • Bonnie Taylor-Blake,

    Affiliation: Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

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  • Arlene S. Bridges,

    Affiliation: Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

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  • Pirkko Vihko,

    Affiliation: Department of Clinical Medicine, Division of Clinical Chemistry, HUSLAB, University of Helsinki, Helsinki, Finland

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  • Mark J. Zylka mail

    zylka@med.unc.edu

    Affiliation: Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

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  • Published: October 31, 2012
  • DOI: 10.1371/journal.pone.0048562

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