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Research Article

Establishment and Characterization of a Highly Tumourigenic and Cancer Stem Cell Enriched Pancreatic Cancer Cell Line as a Well Defined Model System

  • Johannes Fredebohm mail,

    J.Fredebohm@dkfz-heidelberg.de

    Affiliation: Functional Genome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Michael Boettcher,

    Affiliation: Functional Genome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Christian Eisen,

    Affiliation: Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Matthias M. Gaida,

    Affiliation: Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany

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  • Anette Heller,

    Affiliation: European Pancreas Center, University Hospital of Heidelberg, Heidelberg, Germany

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  • Shereen Keleg,

    Affiliation: European Pancreas Center, University Hospital of Heidelberg, Heidelberg, Germany

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  • Jörg Tost,

    Affiliation: Institut de Génomique, Centre National de Génotypage, Evry, France

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  • Karin M. Greulich-Bode,

    Affiliation: Genetics of Skin Carcinogenesis, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Agnes Hotz-Wagenblatt,

    Affiliation: Functional Proteome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Mark Lathrop,

    Affiliation: Institut de Génomique, Centre National de Génotypage, Evry, France

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  • Nathalia A. Giese,

    Affiliation: European Pancreas Center, University Hospital of Heidelberg, Heidelberg, Germany

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  • Jörg D. Hoheisel

    Affiliation: Functional Genome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany

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  • Published: November 12, 2012
  • DOI: 10.1371/journal.pone.0048503

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